Seven 2-tert-butyl-4-chloro-5-（3′-aryl-2′-oxo-5′-oxazolidinylmethoxy）-3（2H）pyridazinones were synthesized via the reaction of aryl isocyanates and 2-tert-butyl-4-chloro-5-（2,3-epoxypropyloxy）-3（2H）（pyridaz...Seven 2-tert-butyl-4-chloro-5-（3′-aryl-2′-oxo-5′-oxazolidinylmethoxy）-3（2H）pyridazinones were synthesized via the reaction of aryl isocyanates and 2-tert-butyl-4-chloro-5-（2,3-epoxypropyloxy）-3（2H）（pyridazinones） prepared by the reaction of 2-tert-butyl-4-chloro-5-hydroxy-3（2H）pyridazinones with epichlorohydrin. The structures of the title compounds were confirmed by 1H NMR, HR MS and IR. The （bioassay） tests showed the inhibition of compound 2b and that of compound 2c against Colletotrichum （lagenarium） under （500 mg/L） were 33% and 50%, respectively.展开更多
Acylation of 2-amio-5-aryl-1,3,4-oxadiazoles with acyl chlorides and trichloroacetic acid to afford eleven new -N--[5-aryl-1,3,4-oxadiazol-2-yl]-substituted amides. The required oxadiazole precursors are prepared by o...Acylation of 2-amio-5-aryl-1,3,4-oxadiazoles with acyl chlorides and trichloroacetic acid to afford eleven new -N--[5-aryl-1,3,4-oxadiazol-2-yl]-substituted amides. The required oxadiazole precursors are prepared by oxidative cyclization of corresponding aldehyde semicarbazones. The structures of the synthesized compounds are elucidated by elemental analysis、 1HNMR、IR and MS. They are screened for their larvicidal activities against wild fruit and antibiotic activities.展开更多
文摘Seven 2-tert-butyl-4-chloro-5-（3′-aryl-2′-oxo-5′-oxazolidinylmethoxy）-3（2H）pyridazinones were synthesized via the reaction of aryl isocyanates and 2-tert-butyl-4-chloro-5-（2,3-epoxypropyloxy）-3（2H）（pyridazinones） prepared by the reaction of 2-tert-butyl-4-chloro-5-hydroxy-3（2H）pyridazinones with epichlorohydrin. The structures of the title compounds were confirmed by 1H NMR, HR MS and IR. The （bioassay） tests showed the inhibition of compound 2b and that of compound 2c against Colletotrichum （lagenarium） under （500 mg/L） were 33% and 50%, respectively.
文摘Acylation of 2-amio-5-aryl-1,3,4-oxadiazoles with acyl chlorides and trichloroacetic acid to afford eleven new -N--[5-aryl-1,3,4-oxadiazol-2-yl]-substituted amides. The required oxadiazole precursors are prepared by oxidative cyclization of corresponding aldehyde semicarbazones. The structures of the synthesized compounds are elucidated by elemental analysis、 1HNMR、IR and MS. They are screened for their larvicidal activities against wild fruit and antibiotic activities.
