A novel synthesis of several isocyanates by direct electrocatalytical carbonylation of corresponding amines can proceed through an electrochemically regenerable palladium(Ⅱ) catalyst in combination with copper acetat...A novel synthesis of several isocyanates by direct electrocatalytical carbonylation of corresponding amines can proceed through an electrochemically regenerable palladium(Ⅱ) catalyst in combination with copper acetate as cocatalyst with an excellent conversion and selectivity under mild conditions. The results show that Pd(PPh 3) 2Cl 2 was the best catalyst. For aromatic amines, the main products were the corresponding isocyanates. And for aliphatic amines, various products were detected.展开更多
A series of aromatic cyanohydrins and their O silyl ethers have been synthesized by trimethylsilylcyanation of aromatic aldehydes using a catalyst generated in situ from optically active R (+) 1,1 2 bisnaphthol with...A series of aromatic cyanohydrins and their O silyl ethers have been synthesized by trimethylsilylcyanation of aromatic aldehydes using a catalyst generated in situ from optically active R (+) 1,1 2 bisnaphthol with n butyl lithium. Mandelonitrile was prepared in an isolated yield 70% with more than \{e.e.\} =60%. The effect of solvents and the amount of catalyst on enantioselectivity was also investigated.展开更多
文摘A novel synthesis of several isocyanates by direct electrocatalytical carbonylation of corresponding amines can proceed through an electrochemically regenerable palladium(Ⅱ) catalyst in combination with copper acetate as cocatalyst with an excellent conversion and selectivity under mild conditions. The results show that Pd(PPh 3) 2Cl 2 was the best catalyst. For aromatic amines, the main products were the corresponding isocyanates. And for aliphatic amines, various products were detected.
文摘A series of aromatic cyanohydrins and their O silyl ethers have been synthesized by trimethylsilylcyanation of aromatic aldehydes using a catalyst generated in situ from optically active R (+) 1,1 2 bisnaphthol with n butyl lithium. Mandelonitrile was prepared in an isolated yield 70% with more than \{e.e.\} =60%. The effect of solvents and the amount of catalyst on enantioselectivity was also investigated.
