Cardiac hypertrophy is intensively related with the morbidity of heart failure,atherosclerosis and stroke.The rat models of left ventricular hypertrophy caused by abdominal aorta constriction and the method of subtrac...Cardiac hypertrophy is intensively related with the morbidity of heart failure,atherosclerosis and stroke.The rat models of left ventricular hypertrophy caused by abdominal aorta constriction and the method of subtractive hybridization to isolate genes expressing differently were used during cardiac hypertrophy.24 cDNA segments were isolated and identified by colony and dot hybridization.Sequence homogenous comparison showed that some of them were very similar to known genes or segments,others were limitedly homogenous and the rest were not found to be significantly homogenous.展开更多
文摘Cardiac hypertrophy is intensively related with the morbidity of heart failure,atherosclerosis and stroke.The rat models of left ventricular hypertrophy caused by abdominal aorta constriction and the method of subtractive hybridization to isolate genes expressing differently were used during cardiac hypertrophy.24 cDNA segments were isolated and identified by colony and dot hybridization.Sequence homogenous comparison showed that some of them were very similar to known genes or segments,others were limitedly homogenous and the rest were not found to be significantly homogenous.
