Objective:Pelvic floor dysfunction is common among pregnant and postpartum women and significantly impacts quality of life.This study aims to translate the German Pelvic Floor Questionnaire for Pregnant and Postpartum...Objective:Pelvic floor dysfunction is common among pregnant and postpartum women and significantly impacts quality of life.This study aims to translate the German Pelvic Floor Questionnaire for Pregnant and Postpartum Women into Chinese and to evaluate its reliability and validity in the Chinese population.Methods:The questionnaire was translated using the Brislin model.A cross-sectional study was conducted among pregnant and postpartum women to assess the content validity,construct validity,Cronbach’sαcoefficient,test-retest reliability,and split-half reliability of the Chinese version.Results:A total of 72 women were included,with 6.9% being pregnant and 93.1% postpartum;the age was(32.3±3.6)years.The Chinese version of the questionnaire contains 4 dimensions and 45 items.The content validity index of individual items ranged from 0.833 to 1.000,with a scale-level content validity index of 0.977 and intraclass correlation coefficients(ICCs)exceeding 0.90.The overall Cronbach’s α coefficient was 0.891,with subscale coefficients ranging from 0.732 to 0.884(all ICCs>0.70).The testretest reliability of the total scale was 0.833,and for the 4 dimensions,bladder,bowel,prolapse,and sexual function,the values were 0.776,0.579,0.732,and 0.645,respectively.The split-half reliability was 0.74.Conclusion:The Chinese version of the questionnaire demonstrated good reliability and validity,indicating its applicability in assessing pelvic floor dysfunction and associated risk factors during pregnancy and postpartum.展开更多
A tracking stability control problem for the vertical electric stabilization system of moving tank based on adaptive robust servo control is addressed.This paper mainly focuses on two types of possibly fast timevaryin...A tracking stability control problem for the vertical electric stabilization system of moving tank based on adaptive robust servo control is addressed.This paper mainly focuses on two types of possibly fast timevarying but bounded uncertainty within the vertical electric stabilization system:model parameter uncertainty and uncertain nonlinearity.First,the vertical electric stabilization system is constructed as an uncertain nonlinear dynamic system that can reflect the practical mechanics transfer process of the system.Second,the dynamical equation in the form of state space is established by designing the angular tracking error.Third,the comprehensive parameter of system uncertainty is designed to estimate the most conservative effects of uncertainty.Finally,an adaptive robust servo control which can effectively handle the combined effects of complex nonlinearity and uncertainty is proposed.The feasibility of the proposed control strategy under the practical physical condition is validated through the tests on the experimental platform.This paper pioneers the introduction of the internal nonlinearity and uncertainty of the vertical electric stabilization system into the settlement of the tracking stability control problem,and validates the advanced servo control strategy through experiment for the first time.展开更多
In order to provide relay communication supports for future Chinese lunar exploration program,Queqiao-2 relay communication satellite was developed.Queqiao-2 can perform scientific observations with three kinds of sci...In order to provide relay communication supports for future Chinese lunar exploration program,Queqiao-2 relay communication satellite was developed.Queqiao-2 can perform scientific observations with three kinds of scientific instruments on board.The system design of Queqiao-2,including mission orbit and transfer orbit design,configuration and layout design,housekeeping and information flow design,power supply and distribution design,GNC and propulsion system design,communication links design,etc.,was accomplished through comprehensive tradeoff and evaluation on technical maturity,availability,schedule,cost,and so on.With a view to reducing development risk,both the platform and relay communication payloads were developed based on significant heritage from previous Queqiao relay satellite and other relevant spacecraft.Queqiao-2 features flexible system architecture to support multiple frequencies,modulations,data rates and software reconfigurations to meet new user requirements.Subsequent to a successful launch on March 20,2024,by means of 5 orbit maneuvers,Queqiao-2 was inserted into a highly elliptical frozen mission orbit around the moon with a 24h period on schedule.Following on-orbit tests and calibrations,Queqiao-2 has possessed the capacity to provide reliable relay communication services to multiple lunar exploration missions,as well as the capacity to perform scientific observations.Under the support of Queqiao-2,Chang′e-6 achieved its ambitious mission goal to collect and return samples from the moon′s mysterious far side.In the meanwhile,Queqiao-2 has also paved the way for the following Chinese lunar exploration missions including Chang′e-7 and Chang′e-8.The design life time of Queqiao-2 is more than 8 years.Benefit from flexibility and extensibility of relay communication system design,it is convenient to provide relay communication services for future lunar exploration missions of both China and other countries.In addition,innovative scientific observations would be performed during the period that no relay communication task is arranged.The system design of Queqiao-2 reflects the development philosophy of technical innovations and inheritance integration.Based on highly flexible and extensible system architecture,multiple and concurrent relay communication mission requirements can be met.It can provide strong supports for future lunar exploration missions.Successful launching,orbit entering and on-orbit tests of Queqiao-2 verified the correct design principle and versatility.By means of Queqiao-2,more innovative scientific outcomes are anticipated and lunar exploration activities can be facilitated.展开更多
To accelerate the practicality of electromagnetic railguns,it is necessary to use a combination of threedimensional numerical simulation and experiments to study the mechanism of bore damage.In this paper,a three-dime...To accelerate the practicality of electromagnetic railguns,it is necessary to use a combination of threedimensional numerical simulation and experiments to study the mechanism of bore damage.In this paper,a three-dimensional numerical model of the augmented railgun with four parallel unconventional rails is introduced to simulate the internal ballistic process and realize the multi-physics field coupling calculation of the rail gun,and a test experiment of a medium-caliber electromagnetic launcher powered by pulse formation network(PFN)is carried out.Various test methods such as spectrometer,fiber grating and high-speed camera are used to test several parameters such as muzzle initial velocity,transient magnetic field strength and stress-strain of rail.Combining the simulation results and experimental data,the damage condition of the contact surface is analyzed.展开更多
Technological trends in the automotive industry toward a software-defined and autonomous vehicle require a reassessment of today’s vehicle development process.The validation process soaringly shapes after starting wi...Technological trends in the automotive industry toward a software-defined and autonomous vehicle require a reassessment of today’s vehicle development process.The validation process soaringly shapes after starting with hardware-in-the-loop testing of control units and reproducing real-world maneuvers and physical interaction chains.Here,the road-to-rig approach offers a vast potential to reduce validation time and costs significantly.The present research study investigates the maneuver reproduction of drivability phenomena at a powertrain test bed.Although drivability phenomena occur in the frequency range of most up to 30∙Hz,the design and characteristics substantially impact the test setup’s validity.By utilization of modal analysis,the influence of the test bed on the mechanical characteristic is shown.Furthermore,the sensitivity of the natural modes of each component,from either specimen or test bed site,is determined.In contrast,the uncertainty of the deployed measurement equipment also affects the validity.Instead of an accuracy class indication,we apply the ISO/IEC Guide 98 to the measurement equipment and the test bed setup to increase the fidelity of the validation task.In conclusion,the present paper contributes to a traceable validity determination of the road-to-rig approach by providing objective metrics and methods.展开更多
中药不论在直接抑制肿瘤生长,还是辅助西医治疗肿瘤方面都发挥着不容忽视的作用.本文经检索中国知网、万方、维普、Pubmed、Web of Science等数据库,纳入中药汤剂联合化疗治疗非小细胞肺癌(NSCLC)的随机对照试验,通过Meta、用药规律、...中药不论在直接抑制肿瘤生长,还是辅助西医治疗肿瘤方面都发挥着不容忽视的作用.本文经检索中国知网、万方、维普、Pubmed、Web of Science等数据库,纳入中药汤剂联合化疗治疗非小细胞肺癌(NSCLC)的随机对照试验,通过Meta、用药规律、网络药理学和细胞实验等分析方法系统评价中药联合化疗治疗NSCLC的疗效、安全性及作用机制,最终纳入56篇文献进行统计分析,共4992例患者、57首处方、172味中药.结果显示,中药联合化疗治疗组的1年生存率、肝功能损伤、总有效率、胃肠道不良反应等方面均优于单纯化疗组.用药频次>20的有7味:药味以甘苦为主,药性以寒温为主,主要归为肺经和肝经.得到5个高频药物聚类,关联规则分析得到置信度最高的4条药物组合为:天花粉-麦冬、玉竹-麦冬、北沙参-玉竹-麦冬、白术-黄芪-党参.收集到核心中药成分潜在作用靶点与NSCLC交集靶点126个;PPI分析得到3个核心靶点:AKT1、EGFR、SRC;KEGG分析表明关键通路为PI3K-Akt信号通路;筛选得到3个关键成分:木犀草素、槲皮素、山柰酚;分子对接结果表明关键成分和核心靶点均能稳定结合.细胞实验结果表明,木犀草素可有效抑制A549细胞的增殖、活力和迁移,诱导其发生凋亡,并使其形态发生变化.本文结果表明,中药联合化疗治疗NSCLC可以提高其临床疗效、降低化疗的毒副作用;黄芪、麦冬、党参、北沙参等核心中药多种成分可通过多靶点、多途径协同治疗NSCLC;关键中药的核心成分木犀草素可抑制A549细胞的增殖、活力和迁移,并可诱导其发生凋亡.展开更多
传统CNN算法在花生荚果外观识别任务中存在内存密集型和计算密集型问题,以及其在资源受限的边缘终端上部署困难,基于此,该研究提出了一种高效的花生荚果识别模型——PPINET(peanut pod identification network),以适应嵌入式设备的资源...传统CNN算法在花生荚果外观识别任务中存在内存密集型和计算密集型问题,以及其在资源受限的边缘终端上部署困难,基于此,该研究提出了一种高效的花生荚果识别模型——PPINET(peanut pod identification network),以适应嵌入式设备的资源限制需求。该模型通过结合深度可分离卷积和倒残差结构显著降低参数量和计算量,同时保留特征提取能力,并引入MQA(multi-query attention)模块增强关键特征提取,并利用TuNAS(easy-to-tune and scalable implementation of efficient neural architecture search with weight sharing)策略优化模型结构,使其在资源受限设备上表现优异。此外,采用ResNet(residual neural network)进行知识蒸馏配合三折交叉验证训练提升精度,最终量化为RKNN格式并在瑞芯微RK3588上实现NPU加速部署。PPINET模型尺寸仅为1.85 MB,参数量为0.49 M,浮点运算数为0.30G。PPINET在花生荚果分类中表现优异,准确率达98.65%,在RK3588上推理速度达321 fps。该模型具备较高的识别准确率和快速的识别速度,能够实现花生荚果的实时精准检测。展开更多
基金supported by the Natural Science Foundation of Hunan Province(2024JJ6626)the Hunan Provincial Key Laboratory of Regional Hereditary Birth Defects Prevention and Control(HPKL202320),China.
文摘Objective:Pelvic floor dysfunction is common among pregnant and postpartum women and significantly impacts quality of life.This study aims to translate the German Pelvic Floor Questionnaire for Pregnant and Postpartum Women into Chinese and to evaluate its reliability and validity in the Chinese population.Methods:The questionnaire was translated using the Brislin model.A cross-sectional study was conducted among pregnant and postpartum women to assess the content validity,construct validity,Cronbach’sαcoefficient,test-retest reliability,and split-half reliability of the Chinese version.Results:A total of 72 women were included,with 6.9% being pregnant and 93.1% postpartum;the age was(32.3±3.6)years.The Chinese version of the questionnaire contains 4 dimensions and 45 items.The content validity index of individual items ranged from 0.833 to 1.000,with a scale-level content validity index of 0.977 and intraclass correlation coefficients(ICCs)exceeding 0.90.The overall Cronbach’s α coefficient was 0.891,with subscale coefficients ranging from 0.732 to 0.884(all ICCs>0.70).The testretest reliability of the total scale was 0.833,and for the 4 dimensions,bladder,bowel,prolapse,and sexual function,the values were 0.776,0.579,0.732,and 0.645,respectively.The split-half reliability was 0.74.Conclusion:The Chinese version of the questionnaire demonstrated good reliability and validity,indicating its applicability in assessing pelvic floor dysfunction and associated risk factors during pregnancy and postpartum.
基金supported in part by the Nation Natural Science Foundation of China under Grant No.52175099China Postdoctoral Science Foundation under Grant No.2020M671494Jiangsu Planned Projects for Postdoctoral Research Funds under Grant No.2020Z179。
文摘A tracking stability control problem for the vertical electric stabilization system of moving tank based on adaptive robust servo control is addressed.This paper mainly focuses on two types of possibly fast timevarying but bounded uncertainty within the vertical electric stabilization system:model parameter uncertainty and uncertain nonlinearity.First,the vertical electric stabilization system is constructed as an uncertain nonlinear dynamic system that can reflect the practical mechanics transfer process of the system.Second,the dynamical equation in the form of state space is established by designing the angular tracking error.Third,the comprehensive parameter of system uncertainty is designed to estimate the most conservative effects of uncertainty.Finally,an adaptive robust servo control which can effectively handle the combined effects of complex nonlinearity and uncertainty is proposed.The feasibility of the proposed control strategy under the practical physical condition is validated through the tests on the experimental platform.This paper pioneers the introduction of the internal nonlinearity and uncertainty of the vertical electric stabilization system into the settlement of the tracking stability control problem,and validates the advanced servo control strategy through experiment for the first time.
文摘In order to provide relay communication supports for future Chinese lunar exploration program,Queqiao-2 relay communication satellite was developed.Queqiao-2 can perform scientific observations with three kinds of scientific instruments on board.The system design of Queqiao-2,including mission orbit and transfer orbit design,configuration and layout design,housekeeping and information flow design,power supply and distribution design,GNC and propulsion system design,communication links design,etc.,was accomplished through comprehensive tradeoff and evaluation on technical maturity,availability,schedule,cost,and so on.With a view to reducing development risk,both the platform and relay communication payloads were developed based on significant heritage from previous Queqiao relay satellite and other relevant spacecraft.Queqiao-2 features flexible system architecture to support multiple frequencies,modulations,data rates and software reconfigurations to meet new user requirements.Subsequent to a successful launch on March 20,2024,by means of 5 orbit maneuvers,Queqiao-2 was inserted into a highly elliptical frozen mission orbit around the moon with a 24h period on schedule.Following on-orbit tests and calibrations,Queqiao-2 has possessed the capacity to provide reliable relay communication services to multiple lunar exploration missions,as well as the capacity to perform scientific observations.Under the support of Queqiao-2,Chang′e-6 achieved its ambitious mission goal to collect and return samples from the moon′s mysterious far side.In the meanwhile,Queqiao-2 has also paved the way for the following Chinese lunar exploration missions including Chang′e-7 and Chang′e-8.The design life time of Queqiao-2 is more than 8 years.Benefit from flexibility and extensibility of relay communication system design,it is convenient to provide relay communication services for future lunar exploration missions of both China and other countries.In addition,innovative scientific observations would be performed during the period that no relay communication task is arranged.The system design of Queqiao-2 reflects the development philosophy of technical innovations and inheritance integration.Based on highly flexible and extensible system architecture,multiple and concurrent relay communication mission requirements can be met.It can provide strong supports for future lunar exploration missions.Successful launching,orbit entering and on-orbit tests of Queqiao-2 verified the correct design principle and versatility.By means of Queqiao-2,more innovative scientific outcomes are anticipated and lunar exploration activities can be facilitated.
文摘To accelerate the practicality of electromagnetic railguns,it is necessary to use a combination of threedimensional numerical simulation and experiments to study the mechanism of bore damage.In this paper,a three-dimensional numerical model of the augmented railgun with four parallel unconventional rails is introduced to simulate the internal ballistic process and realize the multi-physics field coupling calculation of the rail gun,and a test experiment of a medium-caliber electromagnetic launcher powered by pulse formation network(PFN)is carried out.Various test methods such as spectrometer,fiber grating and high-speed camera are used to test several parameters such as muzzle initial velocity,transient magnetic field strength and stress-strain of rail.Combining the simulation results and experimental data,the damage condition of the contact surface is analyzed.
文摘Technological trends in the automotive industry toward a software-defined and autonomous vehicle require a reassessment of today’s vehicle development process.The validation process soaringly shapes after starting with hardware-in-the-loop testing of control units and reproducing real-world maneuvers and physical interaction chains.Here,the road-to-rig approach offers a vast potential to reduce validation time and costs significantly.The present research study investigates the maneuver reproduction of drivability phenomena at a powertrain test bed.Although drivability phenomena occur in the frequency range of most up to 30∙Hz,the design and characteristics substantially impact the test setup’s validity.By utilization of modal analysis,the influence of the test bed on the mechanical characteristic is shown.Furthermore,the sensitivity of the natural modes of each component,from either specimen or test bed site,is determined.In contrast,the uncertainty of the deployed measurement equipment also affects the validity.Instead of an accuracy class indication,we apply the ISO/IEC Guide 98 to the measurement equipment and the test bed setup to increase the fidelity of the validation task.In conclusion,the present paper contributes to a traceable validity determination of the road-to-rig approach by providing objective metrics and methods.
文摘中药不论在直接抑制肿瘤生长,还是辅助西医治疗肿瘤方面都发挥着不容忽视的作用.本文经检索中国知网、万方、维普、Pubmed、Web of Science等数据库,纳入中药汤剂联合化疗治疗非小细胞肺癌(NSCLC)的随机对照试验,通过Meta、用药规律、网络药理学和细胞实验等分析方法系统评价中药联合化疗治疗NSCLC的疗效、安全性及作用机制,最终纳入56篇文献进行统计分析,共4992例患者、57首处方、172味中药.结果显示,中药联合化疗治疗组的1年生存率、肝功能损伤、总有效率、胃肠道不良反应等方面均优于单纯化疗组.用药频次>20的有7味:药味以甘苦为主,药性以寒温为主,主要归为肺经和肝经.得到5个高频药物聚类,关联规则分析得到置信度最高的4条药物组合为:天花粉-麦冬、玉竹-麦冬、北沙参-玉竹-麦冬、白术-黄芪-党参.收集到核心中药成分潜在作用靶点与NSCLC交集靶点126个;PPI分析得到3个核心靶点:AKT1、EGFR、SRC;KEGG分析表明关键通路为PI3K-Akt信号通路;筛选得到3个关键成分:木犀草素、槲皮素、山柰酚;分子对接结果表明关键成分和核心靶点均能稳定结合.细胞实验结果表明,木犀草素可有效抑制A549细胞的增殖、活力和迁移,诱导其发生凋亡,并使其形态发生变化.本文结果表明,中药联合化疗治疗NSCLC可以提高其临床疗效、降低化疗的毒副作用;黄芪、麦冬、党参、北沙参等核心中药多种成分可通过多靶点、多途径协同治疗NSCLC;关键中药的核心成分木犀草素可抑制A549细胞的增殖、活力和迁移,并可诱导其发生凋亡.
