The uncoupling protein(UCP)is a member of the mitochondrial membrane transporter family,which plays an important role in energy metabolism.In the present study,the UCP gene was considered as a candidate gene for chick...The uncoupling protein(UCP)is a member of the mitochondrial membrane transporter family,which plays an important role in energy metabolism.In the present study,the UCP gene was considered as a candidate gene for chicken growth traits,and the association of UCP gene SNPs with growth rate was investigated in the eighth generation of NEAUHLF broiler lines.Two SNPs were found in chicken UCP gene,and the association analysis results showed that both the individual and combination of chicken UCPgene SNPs were significantly associated with body weight of 7 weeks(BW7)and carcass weight(CW)(P〈0.05),and the combination had much significant effects than the single SNP.This research suggested that the UCP gene could be a candidate gene or linked to a major gene which affected growth traits in chicken.展开更多
最近,一种新的呼吸链解偶联产热机制,被哈佛大学科学家公诸于世。经典呼吸链理论认为：解偶联蛋白-1（uncoupling protein 1,UCP1）是机体主要产热因子,其特异性表达在棕色脂肪细胞、米色脂肪细胞的线粒体内膜,并可将线粒体外膜H＋势能...最近,一种新的呼吸链解偶联产热机制,被哈佛大学科学家公诸于世。经典呼吸链理论认为：解偶联蛋白-1（uncoupling protein 1,UCP1）是机体主要产热因子,其特异性表达在棕色脂肪细胞、米色脂肪细胞的线粒体内膜,并可将线粒体外膜H＋势能转化为热能;由于该过程无ATP产生,而只产生热量,因此,亦称为解偶联呼吸（uncoupled respiration）。哈佛大学Dana-Farber癌症中心Spiegelman博士领导的研究组,展开更多
基金Supported by the Earmarked Fund for Modern Agro-industry Technology Research System(CARS-42)Program for Innovation Research Team in University of Heilongjiang Province(2010td02)
文摘The uncoupling protein(UCP)is a member of the mitochondrial membrane transporter family,which plays an important role in energy metabolism.In the present study,the UCP gene was considered as a candidate gene for chicken growth traits,and the association of UCP gene SNPs with growth rate was investigated in the eighth generation of NEAUHLF broiler lines.Two SNPs were found in chicken UCP gene,and the association analysis results showed that both the individual and combination of chicken UCPgene SNPs were significantly associated with body weight of 7 weeks(BW7)and carcass weight(CW)(P〈0.05),and the combination had much significant effects than the single SNP.This research suggested that the UCP gene could be a candidate gene or linked to a major gene which affected growth traits in chicken.
文摘最近,一种新的呼吸链解偶联产热机制,被哈佛大学科学家公诸于世。经典呼吸链理论认为：解偶联蛋白-1（uncoupling protein 1,UCP1）是机体主要产热因子,其特异性表达在棕色脂肪细胞、米色脂肪细胞的线粒体内膜,并可将线粒体外膜H＋势能转化为热能;由于该过程无ATP产生,而只产生热量,因此,亦称为解偶联呼吸（uncoupled respiration）。哈佛大学Dana-Farber癌症中心Spiegelman博士领导的研究组,
