Thermal diffusion of Si atoms at the interface in Mo/Si multilayers was observed with an imaging type soft X ray emission microscope developed by us. It was possible to observe the diffusion with 0.2nm depth resolutio...Thermal diffusion of Si atoms at the interface in Mo/Si multilayers was observed with an imaging type soft X ray emission microscope developed by us. It was possible to observe the diffusion with 0.2nm depth resolution in the direction normal to the interface by comparing the emission intensity for exactly the same position. The diffusion coefficient of Si atoms in Mo at 600℃ was roughly estimated to be 6.0×10 17 cm 2/s.展开更多
The principle of laser optical feedback microscope was presented and demonstrated. Three methods to advance the vertical resolution of laser optical feedback microscope were experimentally studied. The first one is to...The principle of laser optical feedback microscope was presented and demonstrated. Three methods to advance the vertical resolution of laser optical feedback microscope were experimentally studied. The first one is to detect the two polarized lights’ intensities separately with a Wollaston prism instead of to detect the whole light’s intensity. The second is that both of the two orthogonally polarized lights of a birefringent dual frequency laser are fed back. The third one is that only one of the orthogonally polarized lights is fed back. The experimental results show that the modes competition between orthogonally polarized lights can be used to improve the vertical resolution of laser optical feedback microscope effectively.展开更多
The design and fabrication processes of a novel scanner with minimized coupling motions for a high-speed atomic force microscope （AFM） were addressed. An appropriate design modification was proposed through the anal...The design and fabrication processes of a novel scanner with minimized coupling motions for a high-speed atomic force microscope （AFM） were addressed. An appropriate design modification was proposed through the analyses of the dynamic characteristics of existing linear motion stages using a dynamic analysis program, Recurdyn. Because the scanning speed of each direction may differ, the linear motion stage for a high-speed scanner was designed to have different resonance frequencies for the modes, with one dominant displacement in the desired directions. This objective was achieved by using one-direction flexure mechanisms for each direction and mounting one stage for fast motion on the other stage for slow motion. This unsymmetrical configuration separated the frequencies of two vibration modes with one dominant displacement in each desired direction, and hence suppressed the coupling between motions in two directions. A pair of actuators was used for each axis to decrease the crosstalk between the two motions and give a sufficient force to actuate the slow motion stage, which carried the fast motion stage, A lossy material, such as grease, was inserted into the flexure hinge to suppress vibration problems that occurred when using an input triangular waveforrn. With these design modifications and the vibration suppression method, a novel scanner with a scanning speed greater than 20 Hz is achieved.展开更多
A fiber-optic confocal microscope has been analyzed by Fourier optics.It is found that the detected light intensity has three parts,each of which is depennted on the coupled lens,the detective lens,and the part compri...A fiber-optic confocal microscope has been analyzed by Fourier optics.It is found that the detected light intensity has three parts,each of which is depennted on the coupled lens,the detective lens,and the part comprised of the fiber and the microprobe.The simulated results show that the less the value of the parameter A is,which is dependent on the fiber and microprobe,the higher the axial resolution of the system is. For the case,as A→∞, the axial resolution is zero,which is corresponding to the conventional microscope.as A≤1,the axial resolution changes slightly,and is close to the optimal value,which is corresponding to the perfect confocal microscope.when the reflective loss takes place at the end of fiber,the contrast of axial intensity will decrease.All that will help the design of endoscope with confocal microscope at cellular level.展开更多
It is well known that β-BBO is a new type nonlinear optical crystal discovered in our institute and now β-BBO is widely used in the fields of laser and nonlinear optics. However, there are still some inclusions in ...It is well known that β-BBO is a new type nonlinear optical crystal discovered in our institute and now β-BBO is widely used in the fields of laser and nonlinear optics. However, there are still some inclusions in β-BBO crystal grown by flux method. Using AEM technique, we have studied the shape, composition and structure of inclusions which is very helpful to the explanation of the formation of inclusions.展开更多
The realization of real-time thermal feedback for monitoring photothermal therapy(PTT)under near-infrared(NIR)light irradiation is of great interest and challenge for antitumor therapy.Herein,by assembling highly effi...The realization of real-time thermal feedback for monitoring photothermal therapy(PTT)under near-infrared(NIR)light irradiation is of great interest and challenge for antitumor therapy.Herein,by assembling highly efficient photothermal conversion gold nanorods and a temperature-responsive probe((E)-4-(4-(diethylamino)styryl)-1-methylpyridin-1-ium,PyS)within MOF-199,an intelligent nanoplatform(AMPP)was fabricated for simultaneous chemodynamic therapy and NIR light-induced temperature-feedback PTT.The fluorescence intensity and temperature of the PyS probe are linearly related due to the restriction of the rotation of the characteristic monomethine bridge.Moreover,the copper ions resulting from the degradation of MOF-199 in an acidic microenvironment can convert H_(2)O_(2)into•OH,resulting in tumor ablation through a Fenton-like reaction,and this process can be accelerated by increasing the temperature.This study establishes a feasible platform for fabricating highly sensitive temperature sensors for efficient temperature-feedback PTT.展开更多
以硅橡胶为基体,添加无机填料制备的耐热涂层在耐热防腐方面有重要应用前景。采用自制改性硅橡胶作基体,添加不同配比的高岭土、二氧化硅和氧化铝,制备了复合涂层。采用扫描电子显微镜(scanning electron microscopy,SEM)观察了硅橡胶...以硅橡胶为基体,添加无机填料制备的耐热涂层在耐热防腐方面有重要应用前景。采用自制改性硅橡胶作基体,添加不同配比的高岭土、二氧化硅和氧化铝,制备了复合涂层。采用扫描电子显微镜(scanning electron microscopy,SEM)观察了硅橡胶基体中无机填料的分散状况,采用热重分析仪(thermogravimetric analyzer,TGA)对复合涂层的热解温度和失重率进行了分析。结果表明:在复合体系中,无机填料与基体的相容性较好,分散均匀;与基体材料相比,无机填料的添加可有效提高复合材料的耐热性。填料质量分数为20%的复合涂层,其在800℃时质量残留率比自制改性硅橡胶的基体提高了10%以上。展开更多
文摘Thermal diffusion of Si atoms at the interface in Mo/Si multilayers was observed with an imaging type soft X ray emission microscope developed by us. It was possible to observe the diffusion with 0.2nm depth resolution in the direction normal to the interface by comparing the emission intensity for exactly the same position. The diffusion coefficient of Si atoms in Mo at 600℃ was roughly estimated to be 6.0×10 17 cm 2/s.
文摘The principle of laser optical feedback microscope was presented and demonstrated. Three methods to advance the vertical resolution of laser optical feedback microscope were experimentally studied. The first one is to detect the two polarized lights’ intensities separately with a Wollaston prism instead of to detect the whole light’s intensity. The second is that both of the two orthogonally polarized lights of a birefringent dual frequency laser are fed back. The third one is that only one of the orthogonally polarized lights is fed back. The experimental results show that the modes competition between orthogonally polarized lights can be used to improve the vertical resolution of laser optical feedback microscope effectively.
基金Work(R0A-2007-000-20042-0) partly supported by the Second Stage of Brain Korea 21 Projectspartly by the Korea Science and Engineering Foundation (KOSEF) through the National Research Laboratory Program funded by the Ministry of Science and Technology of Korea
文摘The design and fabrication processes of a novel scanner with minimized coupling motions for a high-speed atomic force microscope （AFM） were addressed. An appropriate design modification was proposed through the analyses of the dynamic characteristics of existing linear motion stages using a dynamic analysis program, Recurdyn. Because the scanning speed of each direction may differ, the linear motion stage for a high-speed scanner was designed to have different resonance frequencies for the modes, with one dominant displacement in the desired directions. This objective was achieved by using one-direction flexure mechanisms for each direction and mounting one stage for fast motion on the other stage for slow motion. This unsymmetrical configuration separated the frequencies of two vibration modes with one dominant displacement in each desired direction, and hence suppressed the coupling between motions in two directions. A pair of actuators was used for each axis to decrease the crosstalk between the two motions and give a sufficient force to actuate the slow motion stage, which carried the fast motion stage, A lossy material, such as grease, was inserted into the flexure hinge to suppress vibration problems that occurred when using an input triangular waveforrn. With these design modifications and the vibration suppression method, a novel scanner with a scanning speed greater than 20 Hz is achieved.
文摘A fiber-optic confocal microscope has been analyzed by Fourier optics.It is found that the detected light intensity has three parts,each of which is depennted on the coupled lens,the detective lens,and the part comprised of the fiber and the microprobe.The simulated results show that the less the value of the parameter A is,which is dependent on the fiber and microprobe,the higher the axial resolution of the system is. For the case,as A→∞, the axial resolution is zero,which is corresponding to the conventional microscope.as A≤1,the axial resolution changes slightly,and is close to the optimal value,which is corresponding to the perfect confocal microscope.when the reflective loss takes place at the end of fiber,the contrast of axial intensity will decrease.All that will help the design of endoscope with confocal microscope at cellular level.
文摘It is well known that β-BBO is a new type nonlinear optical crystal discovered in our institute and now β-BBO is widely used in the fields of laser and nonlinear optics. However, there are still some inclusions in β-BBO crystal grown by flux method. Using AEM technique, we have studied the shape, composition and structure of inclusions which is very helpful to the explanation of the formation of inclusions.
基金supported by the National Natural Science Foundation of China(22171001,22305001,51972001,52372073)the Natural Science Foundation of Anhui Province of China(2108085MB49).
文摘The realization of real-time thermal feedback for monitoring photothermal therapy(PTT)under near-infrared(NIR)light irradiation is of great interest and challenge for antitumor therapy.Herein,by assembling highly efficient photothermal conversion gold nanorods and a temperature-responsive probe((E)-4-(4-(diethylamino)styryl)-1-methylpyridin-1-ium,PyS)within MOF-199,an intelligent nanoplatform(AMPP)was fabricated for simultaneous chemodynamic therapy and NIR light-induced temperature-feedback PTT.The fluorescence intensity and temperature of the PyS probe are linearly related due to the restriction of the rotation of the characteristic monomethine bridge.Moreover,the copper ions resulting from the degradation of MOF-199 in an acidic microenvironment can convert H_(2)O_(2)into•OH,resulting in tumor ablation through a Fenton-like reaction,and this process can be accelerated by increasing the temperature.This study establishes a feasible platform for fabricating highly sensitive temperature sensors for efficient temperature-feedback PTT.
文摘以硅橡胶为基体,添加无机填料制备的耐热涂层在耐热防腐方面有重要应用前景。采用自制改性硅橡胶作基体,添加不同配比的高岭土、二氧化硅和氧化铝,制备了复合涂层。采用扫描电子显微镜(scanning electron microscopy,SEM)观察了硅橡胶基体中无机填料的分散状况,采用热重分析仪(thermogravimetric analyzer,TGA)对复合涂层的热解温度和失重率进行了分析。结果表明:在复合体系中,无机填料与基体的相容性较好,分散均匀;与基体材料相比,无机填料的添加可有效提高复合材料的耐热性。填料质量分数为20%的复合涂层,其在800℃时质量残留率比自制改性硅橡胶的基体提高了10%以上。
