Background:The present investigation tested the efficacy of the Tennant Biomodulator,a novel pain management intervention that uses biofeedback-modulated electrical stimulation,to reduce chronic pain and its psychosoc...Background:The present investigation tested the efficacy of the Tennant Biomodulator,a novel pain management intervention that uses biofeedback-modulated electrical stimulation,to reduce chronic pain and its psychosocial sequelae in a sample of current and former military service members.The Tennant Biomodulator used on its most basic setting was compared to two commonly used,non-pharmacological pain treatments—traditional Chinese acupuncture and transcutaneous electrical nerve stimulation(TENS)—in a comparative efficacy,randomized,open-label trial.Methods:Participants included 100 active duty and retired service men and women with chronic pain undergoing treatment at the Brooke Army Medical Center in Texas,USA,randomly assigned to receive six,weekly sessions of either Tennant Biomodulator treatment,traditional Chinese acupuncture,or TENS,in addition to usual care.Recruitment was conducted between May 2010 to September 2013.Outcome measures were collected at intake,before and after each treatment session,and at a 1-month follow-up.Intent-to-treat analyses were used throughout,with mixed models used to investigate main effects of group,time,and group×time interactions with consideration given to quadratic effects.Outcomes measured included ratings of chronic pain,pain-related functional disability,and symptoms of post-traumatic stress disorder(PTSD)and depression.Results:On average,regardless of their treatment group,participants exhibited a 16%reduction in pain measured by the Brooke Army Medical Center’s Clinic Pain Log[F(1,335)=55.7,P<0.0001]and an 11%reduction in pain-related disability measured by the Million Visual Analog Scale[MVAS:F(1,84)=28.3,P<0.0001]from baseline to the end of treatment,but no one treatment performed better than the other,and the reductions in pain and pain-related disability were largely lost by 1-month follow-up.Symptoms of PTSD and depression did not change significantly as a function of time or group.Conclusions:Findings build on previous work suggesting that traditional Chinese acupuncture and TENS can reduce pain and its functional sequelae without risks associated with pharmacological pain management.The Tennant Biomodulator used on its most basic setting performs as well as these other interventions.Based on the present findings,large,randomized controlled trials on the Tennant Biomodulator are indicated.Future work should test this device using its full range of settings for pain-related psychological health.Trial registration:Clincialtrials.gov(NCT01752010);registered December 14,2012.展开更多
目的:系统评价经皮神经电刺激(TENS)对脑卒中患者上肢功能的影响。方法:全面检索8个数据库,包括中国知网、中国维普、万方、PubMed、Web of Science、EMBASE、Cochrane Library、CINAHL,严格按照纳入排除标准进行文献的筛选。采用Cochr...目的:系统评价经皮神经电刺激(TENS)对脑卒中患者上肢功能的影响。方法:全面检索8个数据库,包括中国知网、中国维普、万方、PubMed、Web of Science、EMBASE、Cochrane Library、CINAHL,严格按照纳入排除标准进行文献的筛选。采用Cochrane系统对纳入文献进行质量评价,采用Revman 5.4.1软件进行Meta分析。结果:共纳入了11项随机对照研究,包括559名患者,Meta分析结果显示,TENS可以提高脑卒中上肢功能障碍患者的Fugl-Meyer上肢评估(FMA-UE)量表评分(MD=5.77,95%CI:3.12,8.42)、降低改良Ashworth肌张力评定(MAS)量表评分(MD=-0.38,95%CI:-0.65,-0.11)、提高改良Barthel指数(MBI)评分(MD=10.68,95%CI:8.28,13.09)。亚组分析结果显示,是否偏瘫不是产生异质性的来源。结论:TENS可以提高脑卒中上肢功能障碍患者的FMA-UE量表和MBI评分,降低MAS量表评分,对脑卒中患者的上肢功能恢复有积极影响。展开更多
目的观察经皮神经电刺激(transcutaneous electric nervous stimulation,TENS)用于玻璃体切除联合眼内填充术后面向下体位患者相关疼痛的临床效果。方法便利抽样选取2018年11-12月某院眼科住院的行玻璃体切除联合硅油或气体填充术后需...目的观察经皮神经电刺激(transcutaneous electric nervous stimulation,TENS)用于玻璃体切除联合眼内填充术后面向下体位患者相关疼痛的临床效果。方法便利抽样选取2018年11-12月某院眼科住院的行玻璃体切除联合硅油或气体填充术后需保持面向下体位患者60例60眼,随机分为观察组和对照组。对照组采用常规护理方法,观察组在常规护理的基础上于术后面向下体位2h后予经皮神经电刺激治疗30min。治疗前后采用面部疼痛评分量表(faces pain scale,FPS)对两组患者相关疼痛进行评分。结果术后面向下体位2.5h,观察组面部疼痛评分量表评分较治疗前及对照组显著降低(均P<0.01)。结论经皮神经电刺激可改善玻璃体切除联合眼内填充术后面向下体位患者的相关疼痛,效果确切,值得临床推广应用。展开更多
基金funding source was grant#W81XWH-06-2-0279 from the United States Army Medical Research Acquisition Activity through the Telemedicine and Advanced Technology Research Centerwhich was provided to the Samueli Institutefunding was provided as a gift to the Samueli Institute by an anonymous donor with no conflicts of interest to declare。
文摘Background:The present investigation tested the efficacy of the Tennant Biomodulator,a novel pain management intervention that uses biofeedback-modulated electrical stimulation,to reduce chronic pain and its psychosocial sequelae in a sample of current and former military service members.The Tennant Biomodulator used on its most basic setting was compared to two commonly used,non-pharmacological pain treatments—traditional Chinese acupuncture and transcutaneous electrical nerve stimulation(TENS)—in a comparative efficacy,randomized,open-label trial.Methods:Participants included 100 active duty and retired service men and women with chronic pain undergoing treatment at the Brooke Army Medical Center in Texas,USA,randomly assigned to receive six,weekly sessions of either Tennant Biomodulator treatment,traditional Chinese acupuncture,or TENS,in addition to usual care.Recruitment was conducted between May 2010 to September 2013.Outcome measures were collected at intake,before and after each treatment session,and at a 1-month follow-up.Intent-to-treat analyses were used throughout,with mixed models used to investigate main effects of group,time,and group×time interactions with consideration given to quadratic effects.Outcomes measured included ratings of chronic pain,pain-related functional disability,and symptoms of post-traumatic stress disorder(PTSD)and depression.Results:On average,regardless of their treatment group,participants exhibited a 16%reduction in pain measured by the Brooke Army Medical Center’s Clinic Pain Log[F(1,335)=55.7,P<0.0001]and an 11%reduction in pain-related disability measured by the Million Visual Analog Scale[MVAS:F(1,84)=28.3,P<0.0001]from baseline to the end of treatment,but no one treatment performed better than the other,and the reductions in pain and pain-related disability were largely lost by 1-month follow-up.Symptoms of PTSD and depression did not change significantly as a function of time or group.Conclusions:Findings build on previous work suggesting that traditional Chinese acupuncture and TENS can reduce pain and its functional sequelae without risks associated with pharmacological pain management.The Tennant Biomodulator used on its most basic setting performs as well as these other interventions.Based on the present findings,large,randomized controlled trials on the Tennant Biomodulator are indicated.Future work should test this device using its full range of settings for pain-related psychological health.Trial registration:Clincialtrials.gov(NCT01752010);registered December 14,2012.
文摘目的:系统评价经皮神经电刺激(TENS)对脑卒中患者上肢功能的影响。方法:全面检索8个数据库,包括中国知网、中国维普、万方、PubMed、Web of Science、EMBASE、Cochrane Library、CINAHL,严格按照纳入排除标准进行文献的筛选。采用Cochrane系统对纳入文献进行质量评价,采用Revman 5.4.1软件进行Meta分析。结果:共纳入了11项随机对照研究,包括559名患者,Meta分析结果显示,TENS可以提高脑卒中上肢功能障碍患者的Fugl-Meyer上肢评估(FMA-UE)量表评分(MD=5.77,95%CI:3.12,8.42)、降低改良Ashworth肌张力评定(MAS)量表评分(MD=-0.38,95%CI:-0.65,-0.11)、提高改良Barthel指数(MBI)评分(MD=10.68,95%CI:8.28,13.09)。亚组分析结果显示,是否偏瘫不是产生异质性的来源。结论:TENS可以提高脑卒中上肢功能障碍患者的FMA-UE量表和MBI评分,降低MAS量表评分,对脑卒中患者的上肢功能恢复有积极影响。
