Cocrystallization integrates the merits of high energy and insensitivity between energetic molecules to obtain energetics with satisfying performance.However,how to obtain supramolecular synthons accurately and rapidl...Cocrystallization integrates the merits of high energy and insensitivity between energetic molecules to obtain energetics with satisfying performance.However,how to obtain supramolecular synthons accurately and rapidly for predicting the structure and property of cocrystal remains a challenging problem.In this research,an efficient systematic search approach to predict CL-20/2,4-DNI cocrystal has been proposed that 2,4-DNI revolves around CL-20 with a stoichiometric ratio of 1:1 in accordance with the specified rules(hydrogen bond length:2.2-3.0 Å;search radius:6.5 Å;the number of hydrogen bond:1-3).Eight possible supramolecular synthons were obtained by combining quantum chemistry with molecular mechanics.Crystal structure prediction indicated that there are four structures in cocrystal,namely P21/c,P212121,Pbca and Pna21,and CL-20/2,4-DNI cocrystal is likely to be P21/c and the corresponding cell parameters are Z=4,a=8.28 Å,b=12.17 Å,c=20.42 Å,α=90°,β=96.94°,γ=90°,and ρ=1.9353 g/cm^(3).To further study the intermolecular interaction of CL-20/2,4-DNI cocrystal,a series of theoretical analyses were employed including intermolecular interaction energy,electrostatic potential(ESP),Density of State(DOS),Hirshfeld surface analysis.The C-H…O hydrogen bonds are demonstrated as the predominant driving forces in the cocrystal formation.The mechanical properties and detonation properties of CL-20/2,4-DNI cocrystal implies that the cocrystal shows better ductility and excellent detonation performances(9257 m/s,39.27 GPa)and can serve as a promising energetic material.Cocrystal structure predicted was compared with the experimental one to verify the accuracy of systematic search approach.There is a less than 8.8%error between experiment and predict results,indicating the systematic search approach has extremely high reliability and accuracy.The systematic search approach can be a new strategy to search supramolecular synthons and identify structures effectively and does have the potential to promote the development of energetic cocrystal by theoretical design.展开更多
The family Osmundaceae receives much concern of palaeobotanists for its peculiar sporangia and phylogenetic relationship.Abundant osmundaceous fossils have been reported in China.So far,about 34 species ascribed to se...The family Osmundaceae receives much concern of palaeobotanists for its peculiar sporangia and phylogenetic relationship.Abundant osmundaceous fossils have been reported in China.So far,about 34 species ascribed to seven genera of Osmundaceae have been documented except for three morphogenera.展开更多
Based on the metallogenetic geology conditions, the H, O, C and S isotopic compositions were measured by MAT-251 mass spectrometer, and Pb isotope and Rb-Sr dating were carried with MAT-261 multi-acceptor mass spectro...Based on the metallogenetic geology conditions, the H, O, C and S isotopic compositions were measured by MAT-251 mass spectrometer, and Pb isotope and Rb-Sr dating were carried with MAT-261 multi-acceptor mass spectrometer. The results show that the δ^180 values of gold-bearing vein quartz from different levels are 1.19%-1.42%. The calculated δ^180 values of ore fluids are 0.55%-0.78%, and 319 values are from -8.64% to -6.66%. The calculated values of δ^34SH2s by the δ^34Spy values in quartz veins display sulfur isotope compositions from -0.053% to ＋0.413%. Carbon isotope compositions of carbonates are from -0.612% to 0.140%. The mole ratios of ^206Pb to ^204Pb, ^207Pb to ^204Pb and ^208Pb to ^204Pb in auriferous quartz vein are 16.987-17.545, 15.342-15.623, and 38.254-38.744, respectively. The age of the Zhuanghe gold deposit determined by Rb-Sr isochron of the fluid inclusions in quartzes is （143.0±5.8） Ma. These isotopic data suggest that the metallogenetic fluids are generated from magmatic hydrotherm and the origin of ore-forming matters is related to the deep-derived magmatic activities. Meanwhile, the metallogenetic epoch of the Zhuanghe gold deposit is in Yanshanian period.展开更多
OBJECTIVE To systematically assess the efficacy and safety of acupuncture in treating acute tonsillitis,providing a reference for clinical decision-making.METHODS We searched PubMed,CENTRAL,Embase,Web of Science,China...OBJECTIVE To systematically assess the efficacy and safety of acupuncture in treating acute tonsillitis,providing a reference for clinical decision-making.METHODS We searched PubMed,CENTRAL,Embase,Web of Science,China National Knowledge Infrastruc⁃ture,China Biomedical,clinical research registra⁃tion platforms,grey literature,and the reference lists of the selected studies from inception to Oct.30,2022.The risk of bias assessment used Rev⁃Man.Meta-analysis was performed using STATA with Hedges′g value.In addition,we performed subgroup analysis,meta-regression,and publica⁃tion bias detection with Harbord′s and Egger′s tests.RESULTS We included 19 randomized controlled trials comprising 1701 patients,of which 1 study was assessed high risk of bias.The primary outcome,the response rate,revealed that acupuncture was more effective than antibi⁃otics.The secondary outcomes showed that the difference in the reduction of the VAS scores,sore throat time,and white blood cell counts was statistically significant with acupuncture compared to antibiotics.However,the difference in modulat⁃ing neutrophil percentage and C-reactive protein was not statistically significant.Besides,acupuncture treatments showed a lower incidence of adverse events than antibiotics.CONCLUSION Acupuncture therapy on acute tonsillitis is safe,and the response rate is superior to antibiotics.For alleviating sore throat symptoms,shortening sore throat time,and improving immune in fl am mation index,acupuncture has positive signi fi cance.Nevertheless,because of the limitations of this study,our conclusions should be inter⁃preted with caution.Future efforts still need more high-quality trials to improve the methodology and reporting quality.展开更多
In order to estimate the systematic error in the processof maneuvering target adaptive tracking, a new method is proposed.The proposed method is a linear tracking scheme basedon a modified input estimation approach. A...In order to estimate the systematic error in the processof maneuvering target adaptive tracking, a new method is proposed.The proposed method is a linear tracking scheme basedon a modified input estimation approach. A special augmentationin the state space model is considered, in which both the systematicerror and the unknown input vector are attached to thestate vector. Then, an augmented state model and a measurementmodel are established in the case of systematic error, andthe corresponding filter formulas are also given. In the proposedscheme, the original state, the acceleration and the systematicerror vector can be estimated simultaneously. This method can notonly solve the maneuvering target adaptive tracking problem in thecase of systematic error, but also give the system error value inreal time. Simulation results show that the proposed tracking algorithmoperates in both the non-maneuvering and the maneuveringmodes, and the original state, the acceleration and the systematicerror vector can be estimated simultaneously.展开更多
Two variants of systematic resampling （S-RS） are proposed to increase the diversity of particles and thereby improve the performance of particle filtering when it is utilized for detection in Bell Laboratories Layer...Two variants of systematic resampling （S-RS） are proposed to increase the diversity of particles and thereby improve the performance of particle filtering when it is utilized for detection in Bell Laboratories Layered Space-Time （BLAST） systems. In the first variant, Markov chain Monte Carlo transition is integrated in the S-RS procedure to increase the diversity of particles with large importance weights. In the second one, all particles are first partitioned into two sets according to their importance weights, and then a double S-RS is introduced to increase the diversity of particles with small importance weights. Simulation results show that both variants can improve the bit error performance efficiently compared with the standard S-P^S with little increased complexity.展开更多
1 Introduction
Recent improvements in the precision of Li and B isotope measurements have demonstrated the potential of these elements in tracing a wide range of geological processes. The Li and B isotope sys... 1 Introduction
Recent improvements in the precision of Li and B isotope measurements have demonstrated the potential of these elements in tracing a wide range of geological processes. The Li and B isotope systematics of ultrahigh-pressure (UHP) metamorphic rocks provides a unique opportunity to investigate the behaviour of Li and B during fluid-rock interaction at high temperatures and very high pressures and to constrain the fluid budget and the recycling of subducted crustal materials into the mantle during UHP metamorphism.
……展开更多
A controversial taxon,Hipparion plocodus,is reviewed in the present study.Hi.plocodus has been confirmed to be a valid species with definite diagnostic characteristics,represented by cranial specimens from Baode,Shanx...A controversial taxon,Hipparion plocodus,is reviewed in the present study.Hi.plocodus has been confirmed to be a valid species with definite diagnostic characteristics,represented by cranial specimens from Baode,Shanxi Province.The phylogenetic analysis performed in the present study,with a new matrix,shows that Hi.plocodus forms a monophyletic group with a European species,Hippotherium malpassii.Actually,no close relationship between so-called Hm.malpassii and the genus Hippotherium has been identified,and the record of stratigraphic range of this genus in late stage of Late Miocene is currently absent.Herein previously Hi.plocodus and Hm.malpassii have both attributed into“Hipparion”before the discovery of better material.Evolutionary stages and correlative absolute age showed that these two species should derive independently from some primitive clade.During the late stage of the Late Miocene,the development of the Asian summer monsoon enhanced the humidity of China,with forest and wood habitats expanding considerably under this setting.As the result,one Eurasian closed-habitat lineage thus extended its range into China,which had become very suited for it,give rise to“Hi.”plocodus.展开更多
The transportation sector’s reliance on petroleum fuels exacerbates environmental issues,emphasizing the need for sustainable development.Online electric vehicle(EV)car-hailing services present a key opportunity for ...The transportation sector’s reliance on petroleum fuels exacerbates environmental issues,emphasizing the need for sustainable development.Online electric vehicle(EV)car-hailing services present a key opportunity for EV adoption.This study develops a model based on heuristic and systematic information processing,examining the impacts of factors such as perceived risk,information need,and experience and knowledge on users’utilization of online electric vehicle carhailing services.The results indicate that users’experience and knowledge increase their information need and promote both heuristic and systematic processing,leading to positive attitude change,although they don’t significantly affect perceived risk.Perceived risk increases information need and supports supports systematic processing but negatively impacts attitude change.Greater information enhances systematic processing and attitude change.Perceived risk and information need do not affect attitude change via heuristic processing.Finally,the paper concludes with implications and directions for future research.展开更多
Crop chemical regulation using plant growth regulators(PGRs)represents a key strategy for achieving high-efficiency cotton production in China.This review synthesizes four decades of research on mepiquat chloride(MC),...Crop chemical regulation using plant growth regulators(PGRs)represents a key strategy for achieving high-efficiency cotton production in China.This review synthesizes four decades of research on mepiquat chloride(MC),an inhibitory PGR pivotal to optimizing cotton growth architecture,stress resilience,and yield-quality parameters.We detail MC's stage-specific roles—from root development and flowering acceleration to canopy optimization and assimilate partitioning—and its mechanistic interactions with hormones(e.g.,gibberellin suppression,cytokinin enhancement)under biotic/abiotic stresses.Furthermore,we conceptualize MC deployment into three evolutionary tiers:(1)symptom-guided remedial application,(2)systemic growth-stage programming,and(3)integrated management with agronomic practices.These paradigms,supported by field validation across China's cotton belts,offer a roadmap for precision regulation.Future advancements in nano-formulations,digital agriculture,and PGR synergism are discussed to unlock next-generation yield frontiers.展开更多
Stroke&Vascular Neurology(SVN)新近上线的文章“Risk factors of haemorrhagic transformation for acute ischemic stroke in Chinese patients receiving intravenous recombinant tissue plasminogen activator:a systematic r...Stroke&Vascular Neurology(SVN)新近上线的文章“Risk factors of haemorrhagic transformation for acute ischemic stroke in Chinese patients receiving intravenous recombinant tissue plasminogen activator:a systematic review and meta-analysis”,由四川大学华西医院神经内科何俐教授团队共同完成。展开更多
OBJECTIVE To assess the effi⁃cacy and safety of acupuncture-related treat⁃ments for postherpetic neuralgia(PHN),identify the most effective acupuncture and related treat⁃ments.METHODS PubMed,Cochrane Central Register ...OBJECTIVE To assess the effi⁃cacy and safety of acupuncture-related treat⁃ments for postherpetic neuralgia(PHN),identify the most effective acupuncture and related treat⁃ments.METHODS PubMed,Cochrane Central Register of Controlled Trials,Embase,Web of Science,and four Chinese databases,a clinical research registration platform,and grey literature were searched.We evaluated the risk of bias and quality in the included studies and per⁃formed a Bayesian multiple network meta-analysis.RESULTS We included 29 randomized controlled trials comprising 1973 patients,of which approximately 17.24%showed a high risk of bias.According to the Jadad scale,2,16,and 11 studies were high,medium,and low quality,respectively.The pairwise meta-analysis results revealed that the efficacy of all acupuncture-related treatments for pain relief related to PHN showed the difference was statistically significant com⁃pared with that of antiepileptics.The network meta-analysis results showed that pricking and cupping plus antiepileptics were the most effective,followed by electroacupuncture(EA)plus antiepileptics for pain relief in patients with PHN.EA plus antiepileptics ranked the best regarding reduced Pittsburgh Sleep Quality Index and Self-Rating Depression Scale scores in patients with PHN.No results were found regarding total response rate or quality of life among this study.Acupuncture-related treatments showed a lower incidence of adverse events than that of antiepi⁃leptics-related treatments.CONCLUSION Acu⁃puncture-related therapies may be potential treat⁃ment options for PHN and are relatively safe.Pricking and cupping plus antiepileptics are the most effective techniques for pain relief.EA plus antiepileptics is the best approach for improving insomnia and depression symptoms of PHN.展开更多
A group of graphical models and mathematical models a re used to describe the methods of mass customization (MC). The relationships am ong the models and methods are shown in Fig.1. Fig.1 Relationships among optimizat...A group of graphical models and mathematical models a re used to describe the methods of mass customization (MC). The relationships am ong the models and methods are shown in Fig.1. Fig.1 Relationships among optimization methods for MCThe methods for MC relate to both of product and process, also customized quanti ty and deepness. The methods for MC are integrated by the work in the paper, whi ch can help to understand and use MC better. The optimization and standardization of product is the key for MC. Increasing op timization breadth in product family can help to decrease the customization quan tity in every section of production process. Increasing optimization deepness in products family can help to move the CODCP backward in production process. At the same time, the optimization and standardization of product is the key to reduce cost of customized product. The optimization of the integration of pr oduct and process is the key to reduce lead time of customized product.展开更多
2019年6月24日,《柳叶刀》杂志发表了题为“Mortality,morbidity,and risk factors in China and its province,1990—2017:A systematic analysis for the Global Burden of Disease study 2017”的文章。研究表明,过去近三十年来,中...2019年6月24日,《柳叶刀》杂志发表了题为“Mortality,morbidity,and risk factors in China and its province,1990—2017:A systematic analysis for the Global Burden of Disease study 2017”的文章。研究表明,过去近三十年来,中国慢性非传染性疾病死亡率大幅增加,同时孕产妇和儿童死亡率的持续下降。中风、缺血性心脏病以及肺癌等慢性疾病已成为中国居民过早死亡的主要原因。展开更多
2019年6月4日,《美国临床营养学杂志》( The American Journal of Clinical Nutrition )在线发表王福俤教授团队和闵军霞教授团队最新研究成果论文“Zinc supplementation improves glycemic control for diabetes prevention and manag...2019年6月4日,《美国临床营养学杂志》( The American Journal of Clinical Nutrition )在线发表王福俤教授团队和闵军霞教授团队最新研究成果论文“Zinc supplementation improves glycemic control for diabetes prevention and management: a systematic review and meta-analysis of randomized controlled trials”(https://doi.org/10.1093/ajcn/nqz041),肯定补锌可用于2型糖尿病和妊娠期糖尿病预防及治疗,为糖尿病防控提供了新的视角和策略。展开更多
OBJECTIVE To explore the efficacy of Jiaotai pill(JTW)and JTW modified prescriptions(JTW^(+))plus benzodiazepines(BDZ)for insomnia in China by systematic review and network meta-analysis,especially optimization ratio(...OBJECTIVE To explore the efficacy of Jiaotai pill(JTW)and JTW modified prescriptions(JTW^(+))plus benzodiazepines(BDZ)for insomnia in China by systematic review and network meta-analysis,especially optimization ratio(_(m:n))between Coptis chinensis and Cinnamo.METHODS Randomized controlled trials(RCTs)regarding JTW and JTW^(+)+BDZ for insomina were comprehensively searched in CNKI,VIP,Wanfang,and PubMed,Cochrane Library,OVID,Embase databases from their inception to December 2017.The risk of bias was assessed by the Cochrane collaboration′s tool and Jadad scale.Systematic review and network meta-analysis were performed to evaluate the relative risk(RR)plus 95%confidence interval(95%CI)or prediction interval(95%PrI),and draw surface under the cumulative ranking curves(SUCRA)by Stata 14.0 and RevMan 5.0 software.RESULTS A total of 13 RCTs(1 RCT was omitted by sensitivity analysis)with 1040 patients were included.Overall heterogeneity was acceptable,except publication bias.Based on classical meta-analysis,JTW and JTW_(m:n)^(+)+BDZ,such as JTW_(2:1)^(+)+BDZ,JTW_(5:1)^(+)+BDZ,JTW_(6:1)^(+)+BDZ,JTW_(10:1)^(+)+BDZ,had more efficacy than BDZ.Based on network meta-analysis,JTW and JTW_(m:n)^(+)+BDZ,such as JTW_(2:1)^(+)+BDZ,JTW_(6:1)^(+)+BDZ,JTW_(10:1)^(+)+BDZ,had more efficacy than BDZ;meanwhile,SUCRA showed the best rank of JTW/JTW+(BDZ<JTW_(m:n)^(+)+BDZ<JTW)for insomina,as same as that of JTW_(m:n)+(BDZ<JTW_(5:1)^(+)+BDZ<JTW_(10:1)^(+)+BDZ<JTW_(2:1)^(+)+BDZ<JTW_(6:1)^(+)+BDZ).CONCLUSION Based on the existing clinical evidence,JTW has efficacy for insomnia,but the optimization ratio between Coptis chinensis and cinnamo of JTW_(m:n)^(+)+BDZ for insomnia needs more supports.展开更多
基金the support of the National Natural Science Foundation of China(No.22005090)Beijing Institute of Technology Research Fund Program for Young Scholars+2 种基金the National Natural Science Foundation of China(No.11672040 and No.21801016)Open Research Fund Program of Science and Technology on Aerospace Chemical Power Laboratory(STACPL120201B02)the State Key Laboratory of Explosion Science and Technology(No.YB2016-17)。
文摘Cocrystallization integrates the merits of high energy and insensitivity between energetic molecules to obtain energetics with satisfying performance.However,how to obtain supramolecular synthons accurately and rapidly for predicting the structure and property of cocrystal remains a challenging problem.In this research,an efficient systematic search approach to predict CL-20/2,4-DNI cocrystal has been proposed that 2,4-DNI revolves around CL-20 with a stoichiometric ratio of 1:1 in accordance with the specified rules(hydrogen bond length:2.2-3.0 Å;search radius:6.5 Å;the number of hydrogen bond:1-3).Eight possible supramolecular synthons were obtained by combining quantum chemistry with molecular mechanics.Crystal structure prediction indicated that there are four structures in cocrystal,namely P21/c,P212121,Pbca and Pna21,and CL-20/2,4-DNI cocrystal is likely to be P21/c and the corresponding cell parameters are Z=4,a=8.28 Å,b=12.17 Å,c=20.42 Å,α=90°,β=96.94°,γ=90°,and ρ=1.9353 g/cm^(3).To further study the intermolecular interaction of CL-20/2,4-DNI cocrystal,a series of theoretical analyses were employed including intermolecular interaction energy,electrostatic potential(ESP),Density of State(DOS),Hirshfeld surface analysis.The C-H…O hydrogen bonds are demonstrated as the predominant driving forces in the cocrystal formation.The mechanical properties and detonation properties of CL-20/2,4-DNI cocrystal implies that the cocrystal shows better ductility and excellent detonation performances(9257 m/s,39.27 GPa)and can serve as a promising energetic material.Cocrystal structure predicted was compared with the experimental one to verify the accuracy of systematic search approach.There is a less than 8.8%error between experiment and predict results,indicating the systematic search approach has extremely high reliability and accuracy.The systematic search approach can be a new strategy to search supramolecular synthons and identify structures effectively and does have the potential to promote the development of energetic cocrystal by theoretical design.
文摘The family Osmundaceae receives much concern of palaeobotanists for its peculiar sporangia and phylogenetic relationship.Abundant osmundaceous fossils have been reported in China.So far,about 34 species ascribed to seven genera of Osmundaceae have been documented except for three morphogenera.
基金Project(20040491502) supported by the Doctoral Education Program Fund of Ministry of Education, China
文摘Based on the metallogenetic geology conditions, the H, O, C and S isotopic compositions were measured by MAT-251 mass spectrometer, and Pb isotope and Rb-Sr dating were carried with MAT-261 multi-acceptor mass spectrometer. The results show that the δ^180 values of gold-bearing vein quartz from different levels are 1.19%-1.42%. The calculated δ^180 values of ore fluids are 0.55%-0.78%, and 319 values are from -8.64% to -6.66%. The calculated values of δ^34SH2s by the δ^34Spy values in quartz veins display sulfur isotope compositions from -0.053% to ＋0.413%. Carbon isotope compositions of carbonates are from -0.612% to 0.140%. The mole ratios of ^206Pb to ^204Pb, ^207Pb to ^204Pb and ^208Pb to ^204Pb in auriferous quartz vein are 16.987-17.545, 15.342-15.623, and 38.254-38.744, respectively. The age of the Zhuanghe gold deposit determined by Rb-Sr isochron of the fluid inclusions in quartzes is （143.0±5.8） Ma. These isotopic data suggest that the metallogenetic fluids are generated from magmatic hydrotherm and the origin of ore-forming matters is related to the deep-derived magmatic activities. Meanwhile, the metallogenetic epoch of the Zhuanghe gold deposit is in Yanshanian period.
文摘OBJECTIVE To systematically assess the efficacy and safety of acupuncture in treating acute tonsillitis,providing a reference for clinical decision-making.METHODS We searched PubMed,CENTRAL,Embase,Web of Science,China National Knowledge Infrastruc⁃ture,China Biomedical,clinical research registra⁃tion platforms,grey literature,and the reference lists of the selected studies from inception to Oct.30,2022.The risk of bias assessment used Rev⁃Man.Meta-analysis was performed using STATA with Hedges′g value.In addition,we performed subgroup analysis,meta-regression,and publica⁃tion bias detection with Harbord′s and Egger′s tests.RESULTS We included 19 randomized controlled trials comprising 1701 patients,of which 1 study was assessed high risk of bias.The primary outcome,the response rate,revealed that acupuncture was more effective than antibi⁃otics.The secondary outcomes showed that the difference in the reduction of the VAS scores,sore throat time,and white blood cell counts was statistically significant with acupuncture compared to antibiotics.However,the difference in modulat⁃ing neutrophil percentage and C-reactive protein was not statistically significant.Besides,acupuncture treatments showed a lower incidence of adverse events than antibiotics.CONCLUSION Acupuncture therapy on acute tonsillitis is safe,and the response rate is superior to antibiotics.For alleviating sore throat symptoms,shortening sore throat time,and improving immune in fl am mation index,acupuncture has positive signi fi cance.Nevertheless,because of the limitations of this study,our conclusions should be inter⁃preted with caution.Future efforts still need more high-quality trials to improve the methodology and reporting quality.
基金supported by the National Natural Science Foundation of China(91538201)
文摘In order to estimate the systematic error in the processof maneuvering target adaptive tracking, a new method is proposed.The proposed method is a linear tracking scheme basedon a modified input estimation approach. A special augmentationin the state space model is considered, in which both the systematicerror and the unknown input vector are attached to thestate vector. Then, an augmented state model and a measurementmodel are established in the case of systematic error, andthe corresponding filter formulas are also given. In the proposedscheme, the original state, the acceleration and the systematicerror vector can be estimated simultaneously. This method can notonly solve the maneuvering target adaptive tracking problem in thecase of systematic error, but also give the system error value inreal time. Simulation results show that the proposed tracking algorithmoperates in both the non-maneuvering and the maneuveringmodes, and the original state, the acceleration and the systematicerror vector can be estimated simultaneously.
基金supported by the National Natural Science Foundation of China(6047209860502046U0635003).
文摘Two variants of systematic resampling （S-RS） are proposed to increase the diversity of particles and thereby improve the performance of particle filtering when it is utilized for detection in Bell Laboratories Layered Space-Time （BLAST） systems. In the first variant, Markov chain Monte Carlo transition is integrated in the S-RS procedure to increase the diversity of particles with large importance weights. In the second one, all particles are first partitioned into two sets according to their importance weights, and then a double S-RS is introduced to increase the diversity of particles with small importance weights. Simulation results show that both variants can improve the bit error performance efficiently compared with the standard S-P^S with little increased complexity.
文摘 1 Introduction
Recent improvements in the precision of Li and B isotope measurements have demonstrated the potential of these elements in tracing a wide range of geological processes. The Li and B isotope systematics of ultrahigh-pressure (UHP) metamorphic rocks provides a unique opportunity to investigate the behaviour of Li and B during fluid-rock interaction at high temperatures and very high pressures and to constrain the fluid budget and the recycling of subducted crustal materials into the mantle during UHP metamorphism.
……
文摘A controversial taxon,Hipparion plocodus,is reviewed in the present study.Hi.plocodus has been confirmed to be a valid species with definite diagnostic characteristics,represented by cranial specimens from Baode,Shanxi Province.The phylogenetic analysis performed in the present study,with a new matrix,shows that Hi.plocodus forms a monophyletic group with a European species,Hippotherium malpassii.Actually,no close relationship between so-called Hm.malpassii and the genus Hippotherium has been identified,and the record of stratigraphic range of this genus in late stage of Late Miocene is currently absent.Herein previously Hi.plocodus and Hm.malpassii have both attributed into“Hipparion”before the discovery of better material.Evolutionary stages and correlative absolute age showed that these two species should derive independently from some primitive clade.During the late stage of the Late Miocene,the development of the Asian summer monsoon enhanced the humidity of China,with forest and wood habitats expanding considerably under this setting.As the result,one Eurasian closed-habitat lineage thus extended its range into China,which had become very suited for it,give rise to“Hi.”plocodus.
基金supported by the National Natural Science Foundation of China(72374061)the Ministry of Education Humanities and Social Science Research Youth Project(22YJC630056)+2 种基金the Anhui Provincial Natural Science Foundation(2208085UD02)the Scientific Research Fund of the Hunan Provincial Education Department(23C0677)the Changsha Municipal Planning Project of Philosophy and Social Sciences(2025CSSKKT25)。
文摘The transportation sector’s reliance on petroleum fuels exacerbates environmental issues,emphasizing the need for sustainable development.Online electric vehicle(EV)car-hailing services present a key opportunity for EV adoption.This study develops a model based on heuristic and systematic information processing,examining the impacts of factors such as perceived risk,information need,and experience and knowledge on users’utilization of online electric vehicle carhailing services.The results indicate that users’experience and knowledge increase their information need and promote both heuristic and systematic processing,leading to positive attitude change,although they don’t significantly affect perceived risk.Perceived risk increases information need and supports supports systematic processing but negatively impacts attitude change.Greater information enhances systematic processing and attitude change.Perceived risk and information need do not affect attitude change via heuristic processing.Finally,the paper concludes with implications and directions for future research.
基金supported by the National Key Research and Development Program Projects of China(2024YFD2300600)the China Agriculture Research System(CARS-15-16)。
文摘Crop chemical regulation using plant growth regulators(PGRs)represents a key strategy for achieving high-efficiency cotton production in China.This review synthesizes four decades of research on mepiquat chloride(MC),an inhibitory PGR pivotal to optimizing cotton growth architecture,stress resilience,and yield-quality parameters.We detail MC's stage-specific roles—from root development and flowering acceleration to canopy optimization and assimilate partitioning—and its mechanistic interactions with hormones(e.g.,gibberellin suppression,cytokinin enhancement)under biotic/abiotic stresses.Furthermore,we conceptualize MC deployment into three evolutionary tiers:(1)symptom-guided remedial application,(2)systemic growth-stage programming,and(3)integrated management with agronomic practices.These paradigms,supported by field validation across China's cotton belts,offer a roadmap for precision regulation.Future advancements in nano-formulations,digital agriculture,and PGR synergism are discussed to unlock next-generation yield frontiers.
文摘Stroke&Vascular Neurology(SVN)新近上线的文章“Risk factors of haemorrhagic transformation for acute ischemic stroke in Chinese patients receiving intravenous recombinant tissue plasminogen activator:a systematic review and meta-analysis”,由四川大学华西医院神经内科何俐教授团队共同完成。
基金National Key Research and Development plan for the Modernization of Traditional Chinese Medicine (2018YFC1707700)National Key Research and Development plan for the Modernization of Traditional Chinese Medicine (2018YFC1707706)National Administration of Traditional Chinese Medicine Evidencebased Capacity Building Project (2019XZZXZJ005)
文摘OBJECTIVE To assess the effi⁃cacy and safety of acupuncture-related treat⁃ments for postherpetic neuralgia(PHN),identify the most effective acupuncture and related treat⁃ments.METHODS PubMed,Cochrane Central Register of Controlled Trials,Embase,Web of Science,and four Chinese databases,a clinical research registration platform,and grey literature were searched.We evaluated the risk of bias and quality in the included studies and per⁃formed a Bayesian multiple network meta-analysis.RESULTS We included 29 randomized controlled trials comprising 1973 patients,of which approximately 17.24%showed a high risk of bias.According to the Jadad scale,2,16,and 11 studies were high,medium,and low quality,respectively.The pairwise meta-analysis results revealed that the efficacy of all acupuncture-related treatments for pain relief related to PHN showed the difference was statistically significant com⁃pared with that of antiepileptics.The network meta-analysis results showed that pricking and cupping plus antiepileptics were the most effective,followed by electroacupuncture(EA)plus antiepileptics for pain relief in patients with PHN.EA plus antiepileptics ranked the best regarding reduced Pittsburgh Sleep Quality Index and Self-Rating Depression Scale scores in patients with PHN.No results were found regarding total response rate or quality of life among this study.Acupuncture-related treatments showed a lower incidence of adverse events than that of antiepi⁃leptics-related treatments.CONCLUSION Acu⁃puncture-related therapies may be potential treat⁃ment options for PHN and are relatively safe.Pricking and cupping plus antiepileptics are the most effective techniques for pain relief.EA plus antiepileptics is the best approach for improving insomnia and depression symptoms of PHN.
文摘A group of graphical models and mathematical models a re used to describe the methods of mass customization (MC). The relationships am ong the models and methods are shown in Fig.1. Fig.1 Relationships among optimization methods for MCThe methods for MC relate to both of product and process, also customized quanti ty and deepness. The methods for MC are integrated by the work in the paper, whi ch can help to understand and use MC better. The optimization and standardization of product is the key for MC. Increasing op timization breadth in product family can help to decrease the customization quan tity in every section of production process. Increasing optimization deepness in products family can help to move the CODCP backward in production process. At the same time, the optimization and standardization of product is the key to reduce cost of customized product. The optimization of the integration of pr oduct and process is the key to reduce lead time of customized product.
文摘2019年6月24日,《柳叶刀》杂志发表了题为“Mortality,morbidity,and risk factors in China and its province,1990—2017:A systematic analysis for the Global Burden of Disease study 2017”的文章。研究表明,过去近三十年来,中国慢性非传染性疾病死亡率大幅增加,同时孕产妇和儿童死亡率的持续下降。中风、缺血性心脏病以及肺癌等慢性疾病已成为中国居民过早死亡的主要原因。
文摘2019年6月4日,《美国临床营养学杂志》( The American Journal of Clinical Nutrition )在线发表王福俤教授团队和闵军霞教授团队最新研究成果论文“Zinc supplementation improves glycemic control for diabetes prevention and management: a systematic review and meta-analysis of randomized controlled trials”(https://doi.org/10.1093/ajcn/nqz041),肯定补锌可用于2型糖尿病和妊娠期糖尿病预防及治疗,为糖尿病防控提供了新的视角和策略。
基金National Science and Technology Major Project of China(SQ2017ZX090301064)National Natural Science Foundation of China(81302887)+1 种基金Shandong Science and Technology Development Program(2014GSF119034)and Shandong Science and Technology Development Program of Traditional Chinese Medicine(2017-115,2019-0222)。
文摘OBJECTIVE To explore the efficacy of Jiaotai pill(JTW)and JTW modified prescriptions(JTW^(+))plus benzodiazepines(BDZ)for insomnia in China by systematic review and network meta-analysis,especially optimization ratio(_(m:n))between Coptis chinensis and Cinnamo.METHODS Randomized controlled trials(RCTs)regarding JTW and JTW^(+)+BDZ for insomina were comprehensively searched in CNKI,VIP,Wanfang,and PubMed,Cochrane Library,OVID,Embase databases from their inception to December 2017.The risk of bias was assessed by the Cochrane collaboration′s tool and Jadad scale.Systematic review and network meta-analysis were performed to evaluate the relative risk(RR)plus 95%confidence interval(95%CI)or prediction interval(95%PrI),and draw surface under the cumulative ranking curves(SUCRA)by Stata 14.0 and RevMan 5.0 software.RESULTS A total of 13 RCTs(1 RCT was omitted by sensitivity analysis)with 1040 patients were included.Overall heterogeneity was acceptable,except publication bias.Based on classical meta-analysis,JTW and JTW_(m:n)^(+)+BDZ,such as JTW_(2:1)^(+)+BDZ,JTW_(5:1)^(+)+BDZ,JTW_(6:1)^(+)+BDZ,JTW_(10:1)^(+)+BDZ,had more efficacy than BDZ.Based on network meta-analysis,JTW and JTW_(m:n)^(+)+BDZ,such as JTW_(2:1)^(+)+BDZ,JTW_(6:1)^(+)+BDZ,JTW_(10:1)^(+)+BDZ,had more efficacy than BDZ;meanwhile,SUCRA showed the best rank of JTW/JTW+(BDZ<JTW_(m:n)^(+)+BDZ<JTW)for insomina,as same as that of JTW_(m:n)+(BDZ<JTW_(5:1)^(+)+BDZ<JTW_(10:1)^(+)+BDZ<JTW_(2:1)^(+)+BDZ<JTW_(6:1)^(+)+BDZ).CONCLUSION Based on the existing clinical evidence,JTW has efficacy for insomnia,but the optimization ratio between Coptis chinensis and cinnamo of JTW_(m:n)^(+)+BDZ for insomnia needs more supports.
