Objective To evaluate levels of lead(Pb) and cadmium(Cd) in the breast milk in the second postpartum month,to investigate the relationship between Pb/Cd levels in breast milk and some sociodemographic parameters,and t...Objective To evaluate levels of lead(Pb) and cadmium(Cd) in the breast milk in the second postpartum month,to investigate the relationship between Pb/Cd levels in breast milk and some sociodemographic parameters,and to explore whether these levels affect the infants' physical status or the mothers' psychological status(postpartum depression).Methods A cross-sectional study was conducted between November 2009 and December 2010.Altogether 170 healthy mothers were enrolled from Nanjing Maternity and Child Health Care Hospital.The inclusion criteria were:voluntary to participate in this study,healthy,with no chronic disease,breastfeeding in the second postpartum month,living in a suburban but not non-industrial area of Nanjing,and not occupationally exposed to toxic metals.All the mothers completed a questionnaire and were evaluated based on the Edinburgh Postpartum Depression Scale(EPDS) to identify the risk of postpartum depression.Pb and Cd levels in breast milk were determined by inductively coupled plasma mass spectroscopy.The infants of these mothers were examined for their z scores of weight for age,length for age,head circumference for age,and body mass index for age.Results The median breast milk levels of Pb and Cd were 40.6 μg/L and 0.67 μg/L,respectively.In 164(96.5%) of the 170 samples,Pb levels were higher than the limit reported by the World Health Organization(> 5 μg/L).Breast milk Cd level was > 1 μg/L in 54(31.8%) mothers.The mothers with a history of anemia had a higher breast milk Pb level than those without a history of anemia(41.1 μg/L vs.37.9 μg/L,P = 0.050).The median breast milk Cd level in those who were active and passive smokers during pregnancy was significantly higher than that in non-smokers(0.88 μg/L vs.0.00 μg/L,P = 0.025).The breast milk Cd level in the mothers not taking iron and vitamin supplements for 2 months postpartum was higher than in those taking the supplements(iron supplement:0.74 μg/L vs.0.00 μg/L,P = 0.025;vitamin supplement:0.78 μg/L vs.0.00 μg/L,P = 0.005).Breast milk Cd level at the second postpartum month was negatively correlated with the z scores of head circumference(r = 0.248,P = 0.042) and weight for age at birth(r = 0.241,P = 0.024) in girls.No correlation was found between the breast milk Pb/Cd levels and the EPDS scores.Conclusion Considering the high levels of Pb and Cd in breast milk in this study,breast milk monitoring programs are necessary.展开更多
Once a train stops in a tunnel section and requires emergency evacuation,the large distance between stations and long walking distances in the underground spaces of suburban railway systems pose potential risks to the...Once a train stops in a tunnel section and requires emergency evacuation,the large distance between stations and long walking distances in the underground spaces of suburban railway systems pose potential risks to the evacuation process on tunnel platforms,especially in complex environments.This study utilized Virtual Reality(VR)technology to construct a virtual experimental platform for tunnel evacuation in suburban railway systems,simulating different combinations of smoke and obstacle conditions.By requiring participants to wear VR glasses and walk on an omnidirectional treadmill for moving,as well as complete psychological questionnaires,the study reveals the influences of No Guiding(NG)signs,Wall-Guided(WG)signs,and Central axis Guidance(CG)signs on the movement abilities and psychological behaviors of participants contrastively.The results show that either smoke conditions or obstacle positions affect the mental stress of participants,and the guidance sign has a positive effect on reducing the mental stress.There is an inverse relationship between mental stress and movement abilities.WG and CG signs respectively lead participants to walk closer to walls and along the central axis,which is conducive to reducing the variation in participants’behavior characteristics when circumventing obstacles on the wall side or track side under smoke conditions,respectively.Additionally,CG signs reduce the speed fluctuations of participants before circumventing obstacles,improving the stability of the distance from the wall and speed under smoke conditions,compared to NG and WG signs.These findings contribute to understanding the evacuation psychological-behavioral-movement characteristics of pedestrians on evacuation platforms in suburban railway tunnels and provide a basis for improving the safety design of evacuation guidance signs.展开更多
近年来,随着市域(郊)铁路的发展,网络化、公交化、智能化已成为市域(郊)铁路基本运营需求;当前的信号制式已不能完全满足需求,实现中国列车运行控制系统(China Train Control System,CTCS)与基于通信的列车运行控制系统(Communication B...近年来,随着市域(郊)铁路的发展,网络化、公交化、智能化已成为市域(郊)铁路基本运营需求;当前的信号制式已不能完全满足需求,实现中国列车运行控制系统(China Train Control System,CTCS)与基于通信的列车运行控制系统(Communication Based Train Control System,CBTC)之间的互联互通成为亟待解决的问题。通过分析CTCS与CBTC之间的差异,对几种解决方案进行探讨,详细介绍对CTCS和CBTC信号系统进行适应性修改以及对两种制式进行兼容的解决方案。部分方案已经过实验室测试验证或车辆厂内验证,证明了方案的有效性,可为市域(郊)铁路列控系统的发展提供技术基础和借鉴。展开更多
基金supported by Nanjing Maternity and Child Health Care Hospital
文摘Objective To evaluate levels of lead(Pb) and cadmium(Cd) in the breast milk in the second postpartum month,to investigate the relationship between Pb/Cd levels in breast milk and some sociodemographic parameters,and to explore whether these levels affect the infants' physical status or the mothers' psychological status(postpartum depression).Methods A cross-sectional study was conducted between November 2009 and December 2010.Altogether 170 healthy mothers were enrolled from Nanjing Maternity and Child Health Care Hospital.The inclusion criteria were:voluntary to participate in this study,healthy,with no chronic disease,breastfeeding in the second postpartum month,living in a suburban but not non-industrial area of Nanjing,and not occupationally exposed to toxic metals.All the mothers completed a questionnaire and were evaluated based on the Edinburgh Postpartum Depression Scale(EPDS) to identify the risk of postpartum depression.Pb and Cd levels in breast milk were determined by inductively coupled plasma mass spectroscopy.The infants of these mothers were examined for their z scores of weight for age,length for age,head circumference for age,and body mass index for age.Results The median breast milk levels of Pb and Cd were 40.6 μg/L and 0.67 μg/L,respectively.In 164(96.5%) of the 170 samples,Pb levels were higher than the limit reported by the World Health Organization(> 5 μg/L).Breast milk Cd level was > 1 μg/L in 54(31.8%) mothers.The mothers with a history of anemia had a higher breast milk Pb level than those without a history of anemia(41.1 μg/L vs.37.9 μg/L,P = 0.050).The median breast milk Cd level in those who were active and passive smokers during pregnancy was significantly higher than that in non-smokers(0.88 μg/L vs.0.00 μg/L,P = 0.025).The breast milk Cd level in the mothers not taking iron and vitamin supplements for 2 months postpartum was higher than in those taking the supplements(iron supplement:0.74 μg/L vs.0.00 μg/L,P = 0.025;vitamin supplement:0.78 μg/L vs.0.00 μg/L,P = 0.005).Breast milk Cd level at the second postpartum month was negatively correlated with the z scores of head circumference(r = 0.248,P = 0.042) and weight for age at birth(r = 0.241,P = 0.024) in girls.No correlation was found between the breast milk Pb/Cd levels and the EPDS scores.Conclusion Considering the high levels of Pb and Cd in breast milk in this study,breast milk monitoring programs are necessary.
基金supported by the National Natural Science Foundation of China(Grant Number 52472322)the Shanghai Sailing Program(Grant Number 21YF1415800)+1 种基金the Open Project of Key Laboratory of Advanced Public Transportation Science(Grant Number 2023-APTS-05)the Shanghai SASAC Enterprise Innovation and Capability Enhancement Project(Grant Number 2022016,2023020).
文摘Once a train stops in a tunnel section and requires emergency evacuation,the large distance between stations and long walking distances in the underground spaces of suburban railway systems pose potential risks to the evacuation process on tunnel platforms,especially in complex environments.This study utilized Virtual Reality(VR)technology to construct a virtual experimental platform for tunnel evacuation in suburban railway systems,simulating different combinations of smoke and obstacle conditions.By requiring participants to wear VR glasses and walk on an omnidirectional treadmill for moving,as well as complete psychological questionnaires,the study reveals the influences of No Guiding(NG)signs,Wall-Guided(WG)signs,and Central axis Guidance(CG)signs on the movement abilities and psychological behaviors of participants contrastively.The results show that either smoke conditions or obstacle positions affect the mental stress of participants,and the guidance sign has a positive effect on reducing the mental stress.There is an inverse relationship between mental stress and movement abilities.WG and CG signs respectively lead participants to walk closer to walls and along the central axis,which is conducive to reducing the variation in participants’behavior characteristics when circumventing obstacles on the wall side or track side under smoke conditions,respectively.Additionally,CG signs reduce the speed fluctuations of participants before circumventing obstacles,improving the stability of the distance from the wall and speed under smoke conditions,compared to NG and WG signs.These findings contribute to understanding the evacuation psychological-behavioral-movement characteristics of pedestrians on evacuation platforms in suburban railway tunnels and provide a basis for improving the safety design of evacuation guidance signs.
文摘近年来,随着市域(郊)铁路的发展,网络化、公交化、智能化已成为市域(郊)铁路基本运营需求;当前的信号制式已不能完全满足需求,实现中国列车运行控制系统(China Train Control System,CTCS)与基于通信的列车运行控制系统(Communication Based Train Control System,CBTC)之间的互联互通成为亟待解决的问题。通过分析CTCS与CBTC之间的差异,对几种解决方案进行探讨,详细介绍对CTCS和CBTC信号系统进行适应性修改以及对两种制式进行兼容的解决方案。部分方案已经过实验室测试验证或车辆厂内验证,证明了方案的有效性,可为市域(郊)铁路列控系统的发展提供技术基础和借鉴。
