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Structural design of the fluted shaped charge liner using multi-section optimization method 被引量:1
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作者 Shengjie Sun Jianwei Jiang +2 位作者 Shuyou Wang Jianbing Men Mei Li 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2023年第7期249-262,共14页
Spin effect of the small diameter shaped charge results in the centrifugal stress during the jet stretching process. Consequently, the jet scatters, which deceases the jet penetration capability. In the present study,... Spin effect of the small diameter shaped charge results in the centrifugal stress during the jet stretching process. Consequently, the jet scatters, which deceases the jet penetration capability. In the present study, a multi-section method was proposed to design the spin-compensation liner. The spincompensation rate(SCR) of the liner was defined as the specific angular velocity that a fluted liner can offset. Based on the plain stress theory, SPH numerical method was applied to study the converging process of the 2D fluted structure. The spin-compensation mechanism of the fluted structure was illustrated. Then, nine cross sections were chosen along the liner axis equidistantly. On each of the section, a 2D fluted structure was designed to offset a given initial angular velocity. After, the optimized fluted structures were integrated into a 3D fluted liner. Jet appearances of the normal liner and the fluted liners under different initial angular velocities were compared, which verifies the practicality of the multi-sectional method. The multi-section optimization method provides a new efficient method of designing the shaped charge liner for a specific usage. 展开更多
关键词 Fluted liner Spin-compensation SPH structural optimization
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A hybrid cuckoo search algorithm with feasibility-based rule for constrained structural optimization 被引量:5
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作者 龙文 张文专 +1 位作者 黄亚飞 陈义雄 《Journal of Central South University》 SCIE EI CAS 2014年第8期3197-3204,共8页
Constrained optimization problems are very important as they are encountered in many science and engineering applications.As a novel evolutionary computation technique,cuckoo search(CS) algorithm has attracted much at... Constrained optimization problems are very important as they are encountered in many science and engineering applications.As a novel evolutionary computation technique,cuckoo search(CS) algorithm has attracted much attention and wide applications,owing to its easy implementation and quick convergence.A hybrid cuckoo pattern search algorithm(HCPS) with feasibility-based rule is proposed for solving constrained numerical and engineering design optimization problems.This algorithm can combine the stochastic exploration of the cuckoo search algorithm and the exploitation capability of the pattern search method.Simulation and comparisons based on several well-known benchmark test functions and structural design optimization problems demonstrate the effectiveness,efficiency and robustness of the proposed HCPS algorithm. 展开更多
关键词 constrained optimization problem cuckoo search algorithm pattem search feasibility-based rule engineeringoptimization
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Optimization on Inlet Deflectors Structural Parameters of a Natural Draft Counter-flow Wet Cooling Tower 被引量:1
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作者 HU Danmei ZONG Tao +1 位作者 ZHANG Zhichao ZHANG Jianping 《中国电机工程学报》 EI CSCD 北大核心 2013年第11期I0005-I0005,共1页
The cooling process of cooling water is veryimportant in power generation industry.The performanceof cooling towers has a great effect on security,stabilityand economy of power plants.The energy savingproblems of the ... The cooling process of cooling water is veryimportant in power generation industry.The performanceof cooling towers has a great effect on security,stabilityand economy of power plants.The energy savingproblems of the cooling tower have always beenneglected previously.With the aim of energy saving inthe power plants nowadays,improving the coolingefficiency of the cooling tower has important andpractical significance. 展开更多
关键词 cooling tower heat and mass transfer DEFLECTOR numerical simulation optimization
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Optimization of structural parameters for spatial flexible redundant manipulators with maximum ratio of load to mass 被引量:1
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作者 ZHANG Xu-ping YU Yue-qing 《光学精密工程》 EI CAS CSCD 北大核心 2005年第5期561-569,共9页
Optimization of structural parameters aimed at improving the load carrying capacity of spatial flexible redundant manipulators is presented in this paper. In order to increase the ratio of load to mass of robots, the ... Optimization of structural parameters aimed at improving the load carrying capacity of spatial flexible redundant manipulators is presented in this paper. In order to increase the ratio of load to mass of robots, the cross-sectional parameters and constructional parameters are optimized respectively. The cross-sectional and configurational parameters are optimized simultaneously. The numerical simulation of a 4R spatial manipulator is performed. The results show that the load capacity of robots has been greatly improved through the optimization strategies proposed in this paper. 展开更多
关键词 调节器 结构参数 机器人 动力性质 KED
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Status and Development of Rapid Detection Technology for Tunnel Structural Defects 被引量:3
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作者 LIU Xuezeng FANG Maoliu +3 位作者 WU Dexing LI Yinping LIU Xingen LI Gang 《隧道建设(中英文)》 北大核心 2025年第4期657-676,I0005-I0024,共40页
Based on inspection data,the authors analyze and summarize the main types and distribution characteristics of tunnel structural defects.These defects are classified into three types:surface defects,internal defects,an... Based on inspection data,the authors analyze and summarize the main types and distribution characteristics of tunnel structural defects.These defects are classified into three types:surface defects,internal defects,and defects behind the structure.To address the need for rapid detection of different defect types,the current state of rapid detection technologies and equipment,both domestically and internationally,is systematically reviewed.The research reveals that surface defect detection technologies and equipment have developed rapidly in recent years.Notably,the integration of machine vision and laser scanning technologies have significantly improved detection efficiency and accuracy,achieving crack detection precision of up to 0.1 mm.However,the non-contact rapid detection of internal and behind-the-structure defects remains constrained by hardware limitations,with traditional detection remaining dominant.Nevertheless,phased array radar,ultrasonic,and acoustic vibration detection technologies have become research hotspots in recent years,offering promising directions for detecting these challenging defect types.Additionally,the application of multisensor fusion technology in rapid detection equipment has further enhanced detection capabilities.Devices such as cameras,3D laser scanners,infrared thermal imagers,and radar demonstrate significant advantages in rapid detection.Future research in tunnel inspection should prioritize breakthroughs in rapid detection technologies for internal and behind-the-structure defects.Efforts should also focus on developing multifunctional integrated detection vehicles that can simultaneously inspect both surface and internal structures.Furthermore,progress in fully automated,intelligent systems with precise defect identification and real-time reporting will be essential to significantly improve the efficiency and accuracy of tunnel inspection. 展开更多
关键词 TUNNEL structural defect inspection techniques inspection equipment rapid inspection
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Structural Color Dynamic Graphics Display Based on Microlens Array 被引量:1
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作者 LI Xue-han LIU Ling-zhi +1 位作者 HUANG Min LI Xiu 《印刷与数字媒体技术研究》 北大核心 2025年第2期162-168,共7页
It is of great scientific significance to construct a 3D dynamic structural color with a special color effect based on the microlens array.However,the problems of imperfect mechanisms and poor color quality need to be... It is of great scientific significance to construct a 3D dynamic structural color with a special color effect based on the microlens array.However,the problems of imperfect mechanisms and poor color quality need to be solved.A method of 3D structural color turning on periodic metasurfaces fabricated by the microlens array and self-assembly technology was proposed in this study.In the experiment,Polydimethylsiloxane(PDMS)flexible film was used as a substrate,and SiO2 microspheres were scraped into grooves of the PDMS film to form 3D photonic crystal structures.By adjusting the number of blade-coated times and microsphere concentrations,high-saturation structural color micropatterns were obtained.These films were then matched with microlens arrays to produce dynamic graphics with iridescent effects.The results showed that by blade-coated two times and SiO2 microsphere concentrations of 50%are the best conditions.This method demonstrates the potential for being widely applied in the anticounterfeiting printing and ultra-high-resolution display. 展开更多
关键词 structural color Microlens array Dynamic graphics display Moirémagnification Optical anti-counterfeiting
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Multi-objective optimization of grinding process parameters for improving gear machining precision 被引量:1
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作者 YOU Tong-fei HAN Jiang +4 位作者 TIAN Xiao-qing TANG Jian-ping LU Yi-guo LI Guang-hui XIA Lian 《Journal of Central South University》 2025年第2期538-551,共14页
The gears of new energy vehicles are required to withstand higher rotational speeds and greater loads,which puts forward higher precision essentials for gear manufacturing.However,machining process parameters can caus... The gears of new energy vehicles are required to withstand higher rotational speeds and greater loads,which puts forward higher precision essentials for gear manufacturing.However,machining process parameters can cause changes in cutting force/heat,resulting in affecting gear machining precision.Therefore,this paper studies the effect of different process parameters on gear machining precision.A multi-objective optimization model is established for the relationship between process parameters and tooth surface deviations,tooth profile deviations,and tooth lead deviations through the cutting speed,feed rate,and cutting depth of the worm wheel gear grinding machine.The response surface method(RSM)is used for experimental design,and the corresponding experimental results and optimal process parameters are obtained.Subsequently,gray relational analysis-principal component analysis(GRA-PCA),particle swarm optimization(PSO),and genetic algorithm-particle swarm optimization(GA-PSO)methods are used to analyze the experimental results and obtain different optimal process parameters.The results show that optimal process parameters obtained by the GRA-PCA,PSO,and GA-PSO methods improve the gear machining precision.Moreover,the gear machining precision obtained by GA-PSO is superior to other methods. 展开更多
关键词 worm wheel gear grinding machine gear machining precision machining process parameters multi objective optimization
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Max-Min Security Rate Optimization in STAR-RIS Aided Secure MIMO Systems
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作者 HUANG Jinhao MIAO Ling +1 位作者 SUO Long ZHOU Wen 《电讯技术》 北大核心 2025年第10期1657-1664,共8页
The simultaneous transmitting and reflecting reconfigurable intelligent surface(STAR-RIS)can independently adjust surface’s reflection and transmission coefficients so as to enhance space coverage.For a multiple-inpu... The simultaneous transmitting and reflecting reconfigurable intelligent surface(STAR-RIS)can independently adjust surface’s reflection and transmission coefficients so as to enhance space coverage.For a multiple-input multiple-output(MIMO)communication system with a STAR-RIS,a base station(BS),an eavesdropper,and multiple users,the system security rate is studied.A joint design of the power allocation at the transmitter and phase shift matrices for reflection and transmission at the STAR-RIS is conducted,in order to maximize the worst achievable security data rate(ASDR).Since the problem is nonconvex and hence challenging,a particle swarm optimization(PSO)based algorithm is developed to tackle the problem.Both the cases of continuous and discrete phase shift matrices at the STAR-RIS are considered.Simulation results demonstrate the effectiveness of the proposed algorithm and shows the benefits of using STAR-RIS in MIMO mutliuser systems. 展开更多
关键词 multiple-input multiple-output(MIMO) reflecting reconfigurable intelligent surface(STAR-RIS) particle swarm optimization(PSO) max-min security rate optimization
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A high output power 340 GHz balanced frequency doubler designed based on linear optimization method
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作者 LIU Zhi-Cheng ZHOU Jing-Tao +5 位作者 MENG Jin WEI Hao-Miao YANG Cheng-Yue SU Yong-Bo JIN Zhi JIA Rui 《红外与毫米波学报》 北大核心 2025年第2期184-191,共8页
In this paper,a linear optimization method(LOM)for the design of terahertz circuits is presented,aimed at enhancing the simulation efficacy and reducing the time of the circuit design workflow.This method enables the ... In this paper,a linear optimization method(LOM)for the design of terahertz circuits is presented,aimed at enhancing the simulation efficacy and reducing the time of the circuit design workflow.This method enables the rapid determination of optimal embedding impedance for diodes across a specific bandwidth to achieve maximum efficiency through harmonic balance simulations.By optimizing the linear matching circuit with the optimal embedding impedance,the method effectively segregates the simulation of the linear segments from the nonlinear segments in the frequency multiplier circuit,substantially improving the speed of simulations.The design of on-chip linear matching circuits adopts a modular circuit design strategy,incorporating fixed load resistors to simplify the matching challenge.Utilizing this approach,a 340 GHz frequency doubler was developed and measured.The results demonstrate that,across a bandwidth of 330 GHz to 342 GHz,the efficiency of the doubler remains above 10%,with an input power ranging from 98 mW to 141mW and an output power exceeding 13 mW.Notably,at an input power of 141 mW,a peak output power of 21.8 mW was achieved at 334 GHz,corresponding to an efficiency of 15.8%. 展开更多
关键词 linear optimization method(LOM) three-dimensional electromagnetic model(3D-EM) Harmonic impedance optimization Schottky planar diode Terahertz frequency doubler
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Effects of Ultrasound-Assisted Alkaline Extraction on the Structural and Emulsifying Properties of Chickpea Protein Isolate
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作者 ZHANG Yixue YANG Qing +4 位作者 CHENG Teng ZHENG Ruihan MA Wuchao HE Xiangli LI Ke 《食品科学》 北大核心 2025年第19期236-247,共12页
This study aimed to investigate the effect of ultrasound-assisted alkaline extraction(UAE)(at 20 kHz and different powers of 0,200,300,400,500 and 600 W for 10 min)on the yield,structure and emulsifying properties of ... This study aimed to investigate the effect of ultrasound-assisted alkaline extraction(UAE)(at 20 kHz and different powers of 0,200,300,400,500 and 600 W for 10 min)on the yield,structure and emulsifying properties of chickpea protein isolate(CPI).Compared with the non-ultrasound group,ultrasound treatment at 400 W resulted in the largest increase in CPI yield,and both the particle size and turbidity decreased with increasing ultrasound power from 0 to 400 W.The scanning electron microscope results showed a uniform structural distribution of CPI.Moreover,itsα-helix content increased,β-sheet content decreased,and total sulfhydryl group content and endogenous fluorescence intensity rose,illustrating that UAE changed the secondary and tertiary structure of CPI.At 400 W,the solubility of the emulsion increased to 63.18%,and the best emulsifying properties were obtained;the emulsifying activity index(EAI)and emulsifying stability index(ESI)increased by 85.42%and 46.78%,respectively.Furthermore,the emulsion droplets formed were smaller and more uniform.In conclusion,proper UAE power conditions increased the extraction yield and protein content of CPI,and effectively improved its structure and emulsifying characteristics. 展开更多
关键词 CHICKPEA ULTRASOUND extraction yield protein structure functional properties
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Energy Efficiency Operating Indicator Forecasting and Speed Design Optimization for Polar Ice Class Merchant Vessels
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作者 LU Yu LI Chen−ran +3 位作者 ZHU Xiang−hang LI Shi−an GU Zhu−hao LIU She−wen 《船舶力学》 北大核心 2025年第6期901-911,共11页
In order to accurately forecast the main engine fuel consumption and reduce the Energy Efficiency Operational Indicator(EEOI)of merchant ships in polar ice areas,the energy transfer relationship between ship-machine-p... In order to accurately forecast the main engine fuel consumption and reduce the Energy Efficiency Operational Indicator(EEOI)of merchant ships in polar ice areas,the energy transfer relationship between ship-machine-propeller is studied by analyzing the complex force situation during ship navigation and building a MATLAB/Simulink simulation platform based on multi-environmental resistance,propeller efficiency,main engine power,fuel consumption,fuel consumption rate and EEOI calculation module.Considering the environmental factors of wind,wave and ice,the route is divided into sections,the calculation of main engine power,main engine fuel consumption and EEOI for each section is completed,and the speed design is optimized based on the simulation model for each section.Under the requirements of the voyage plan,the optimization results show that the energy efficiency operation index of the whole route is reduced by 3.114%and the fuel consumption is reduced by 9.17 t. 展开更多
关键词 Energy Efficiency Operational Indicator ice-class ships segment division design optimization
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Design and optimization of quadrupole and sextupole magnets for Shenzhen Innovation Light-source Facility storage ring
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作者 Zhu Jiawu Zhang Miao Wang Yong 《强激光与粒子束》 北大核心 2025年第7期83-90,共8页
As an advanced 4^(th) generation synchrotron radiation facility,the Shenzhen Innovation Light-source Facility(SILF)storage ring is based on multi-bend achromat(MBA)lattices,enabling one to two orders of magnitude redu... As an advanced 4^(th) generation synchrotron radiation facility,the Shenzhen Innovation Light-source Facility(SILF)storage ring is based on multi-bend achromat(MBA)lattices,enabling one to two orders of magnitude reduction in beam emittance compared to the 3^(rd) generation storage ring.This significantly enhance the radiation brightness and coherence.The multipole magnets of many types for SILF storage ring are under preliminary design,which require high integral field homogeneity.As a result,a dedicated pole tip optimization procedure with high efficiency is developed for quadrupole and sextupole magnets with Opera-2D^(■)python script.The procedure considers also the 3D field effect which makes the optimization more straightforward.In this paper,the design of the quadrupole and sextupole magnets for SILF storage ring is first presented,followed by a detailed description of the implemented pole shape optimization method. 展开更多
关键词 synchrotron radiation facility quadrupole magnet sextupole magnet pole shape optimization
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A Modified PRP-HS Hybrid Conjugate Gradient Algorithm for Solving Unconstrained Optimization Problems
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作者 LI Xiangli WANG Zhiling LI Binglan 《应用数学》 北大核心 2025年第2期553-564,共12页
In this paper,we propose a three-term conjugate gradient method for solving unconstrained optimization problems based on the Hestenes-Stiefel(HS)conjugate gradient method and Polak-Ribiere-Polyak(PRP)conjugate gradien... In this paper,we propose a three-term conjugate gradient method for solving unconstrained optimization problems based on the Hestenes-Stiefel(HS)conjugate gradient method and Polak-Ribiere-Polyak(PRP)conjugate gradient method.Under the condition of standard Wolfe line search,the proposed search direction is the descent direction.For general nonlinear functions,the method is globally convergent.Finally,numerical results show that the proposed method is efficient. 展开更多
关键词 Conjugate gradient method Unconstrained optimization Sufficient descent condition Global convergence
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Numerical Analysis on Influence of Preset Bubble in a Fluidfilled Structure on the Characteristics of Projectile Penetration and Structural Failure
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作者 WU Meng−meng HOU Hai−liang +3 位作者 LI Dian LI Yong−qing XIA Wei−xue YANG Shao−hong 《船舶力学》 北大核心 2025年第6期924-940,共17页
In this paper,the failure caused by HRAM loads which were generated by high-speed projectile penetration,and protection technology of the fluid-filled structure were explored.A bubble was preset on the projectile traj... In this paper,the failure caused by HRAM loads which were generated by high-speed projectile penetration,and protection technology of the fluid-filled structure were explored.A bubble was preset on the projectile trajectory in a fluid-filled structure.Based on the reflection and transmission phenomena of pressure waves at the gas-liquid interface and the compressibility characteristics of gases,a numerical analysis was conducted on the influence of preset bubble on projectile penetration and structural failure characteristics.The results indicate that the secondary water-entry impact phenomenon occurs when a preset bubble exists on the projectile trajectory,leading to the secondary water entry impact loads.The rarefaction waves reflected on the surface of the preset bubble cause the attenuation ratio of the initial impact pressure peak to reach 68.8%and the total specific impulse attenuation ratio to reach 48.6%.Furthermore,the larger the bubble,the faster the projectile,and the more obvious the attenuation effect.Moreover,due to the compressibility of the bubble,the global deformation attenuation ratio of the front and rear walls can reach over 80%.However,the larger the bubble size,the faster the projectile velocity,the smaller the local deformation attenuation effect of the rear wall,and the more severe the failure at the perforation of the rear wall. 展开更多
关键词 fluid-filled structure preset bubble HRAM loads PROJECTILE PENETRATION ATTENUATION
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Some studies on stochastic optimization based quantitative risk management
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作者 HU Zhaolin 《运筹学学报(中英文)》 北大核心 2025年第3期135-159,共25页
Risk management often plays an important role in decision making un-der uncertainty.In quantitative risk management,assessing and optimizing risk metrics requires eficient computing techniques and reliable theoretical... Risk management often plays an important role in decision making un-der uncertainty.In quantitative risk management,assessing and optimizing risk metrics requires eficient computing techniques and reliable theoretical guarantees.In this pa-per,we introduce several topics on quantitative risk management and review some of the recent studies and advancements on the topics.We consider several risk metrics and study decision models that involve the metrics,with a main focus on the related com-puting techniques and theoretical properties.We show that stochastic optimization,as a powerful tool,can be leveraged to effectively address these problems. 展开更多
关键词 stochastic optimization quantitative risk management risk measure computing technique statistical property
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Design of broadband achromatic far-infrared metalens based on chalcogenide glass using parameterized topology optimization
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作者 ZHOU Yun-fei ZOU Lin-er +1 位作者 CHENG Yang-bing SHEN Yun 《中国光学(中英文)》 北大核心 2025年第6期1475-1483,共9页
Metalens technology has been applied extensively in miniaturized and integrated infrared imaging systems.However,due to the high phase dispersion of unit structures,metalens often exhibits chromatic aberration,making ... Metalens technology has been applied extensively in miniaturized and integrated infrared imaging systems.However,due to the high phase dispersion of unit structures,metalens often exhibits chromatic aberration,making broadband achromatic infrared imaging challenging to achieve.In this paper,six different unit structures based on chalcogenide glass are constructed,and their phase-dispersion parameters are analyzed to establish a database.On this basis,using chromatic aberration compensation and parameterized adjoint topology optimization,a broadband achromatic metalens with a numerical aperture of 0.5 is designed by arranging these six unit structures in the far-infrared band.Simulation results show that the metalens achieves near diffraction-limited focusing within the operating wavelength range of 9−11μm,demonstrating the good performance of achromatic aberration with flat focusing efficiency of 54%−58%across all wavelengths. 展开更多
关键词 metalens chalcogenide glass topology optimization high efficiency long wave infrared broadband operation
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An Algorithm for Cloud-based Web Service Combination Optimization Through Plant Growth Simulation
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作者 Li Qiang Qin Huawei +1 位作者 Qiao Bingqin Wu Ruifang 《系统仿真学报》 北大核心 2025年第2期462-473,共12页
In order to improve the efficiency of cloud-based web services,an improved plant growth simulation algorithm scheduling model.This model first used mathematical methods to describe the relationships between cloud-base... In order to improve the efficiency of cloud-based web services,an improved plant growth simulation algorithm scheduling model.This model first used mathematical methods to describe the relationships between cloud-based web services and the constraints of system resources.Then,a light-induced plant growth simulation algorithm was established.The performance of the algorithm was compared through several plant types,and the best plant model was selected as the setting for the system.Experimental results show that when the number of test cloud-based web services reaches 2048,the model being 2.14 times faster than PSO,2.8 times faster than the ant colony algorithm,2.9 times faster than the bee colony algorithm,and a remarkable 8.38 times faster than the genetic algorithm. 展开更多
关键词 cloud-based service scheduling algorithm resource constraint load optimization cloud computing plant growth simulation algorithm
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Multi-objective optimization of top-level arrangement for flight test
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作者 WANG Yunong BI Wenhao +2 位作者 FAN Qiucen XU Shuangfei ZHANG An 《Journal of Systems Engineering and Electronics》 2025年第3期714-724,共11页
The lack of systematic and scientific top-level arrangement in the field of civil aircraft flight test leads to the problems of long duration and high cost.Based on the flight test activity,mathematical models of flig... The lack of systematic and scientific top-level arrangement in the field of civil aircraft flight test leads to the problems of long duration and high cost.Based on the flight test activity,mathematical models of flight test duration and cost are established to set up the framework of flight test process.The top-level arrangement for flight test is optimized by multi-objective algorithm to reduce the duration and cost of flight test.In order to verify the necessity and validity of the mathematical models and the optimization algorithm of top-level arrangement,real flight test data is used to make an example calculation.Results show that the multi-objective optimization results of the top-level flight arrangement are better than the initial arrangement data,which can shorten the duration,reduce the cost,and improve the efficiency of flight test. 展开更多
关键词 flight test top-level arrangement flight test optimization multi-objective optimization
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Layout configuration and joint scheduling optimization of green-grey-blue integrated system for urban stormwater management:Current status and future directions
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作者 DUAN Tingting LI Pengfeng +4 位作者 KHU Soonthiam HUANG Peng TIAN Tengfei LIU Qian ZHANG Yuting 《水利水电技术(中英文)》 北大核心 2025年第7期77-108,共32页
[Objective]Under the combined impact of climate change and urbanization,urban rainstorm flood disasters occur frequently,seriously restricting urban safety and sustainable development.Relying on traditional grey infra... [Objective]Under the combined impact of climate change and urbanization,urban rainstorm flood disasters occur frequently,seriously restricting urban safety and sustainable development.Relying on traditional grey infrastructure such as pipe networks for urban stormwater management is not enough to deal with urban rainstorm flood disasters under extreme rainfall events.The integration of green,grey and blue systems(GGB-integrated system)is gradually gaining recognition in the field of global flood prevention.It is necessary to further clarify the connotation,technical and engineering implementation strategies of the GGB-integrated system,to provide support for the resilient city construction.[Methods]Through literature retrieval and analysis,the relevant research and progress related to the layout optimization and joint scheduling optimization of the GGBintegrated system were systematically reviewed.In response to existing limitations and future engineering application requirements,key supporting technologies including the utilization of overground emergency storage spaces,safety protection of underground important infrastructure and multi-departmental collaboration,were proposed.A layout optimization framework and a joint scheduling framework for the GGB-integrated system were also developed.[Results]Current research on layout optimization predominantly focuses on the integration of green system and grey system,with relatively fewer studies incorporating blue system infrastructure into the optimization process.Moreover,these studies tend to be on a smaller scale with simpler scenarios,which do not fully capture the complexity of real-world systems.Additionally,optimization objective tend to prioritize environmental and economic goals,while social and ecological factors are less frequently considered.Current research on joint scheduling optimization is often limited to small-scale plots,with insufficient attention paid to the entire system.There is a deficiency in method for real-time,automated determination of optimal control strategies for combinations of multiple system facilities based on actual rainfall-runoff processes.Additionally,the application of emergency facilities during extreme conditions is not sufficiently addressed.Furthermore,both layout optimization and joint scheduling optimization lack consideration of the mute feed effect of flood and waterlogging in urban,watershed and regional scales.[Conclusion]Future research needs to improve the theoretical framework for layout optimization and joint scheduling optimization of GGB-integrated system.Through the comprehensive application of the Internet of things,artificial intelligence,coupling model development,multi-scale analysis,multi-scenario simulation,and the establishment of multi-departmental collaboration mechanisms,it can enhance the flood resilience of urban areas in response to rainfall events of varying intensities,particularly extreme rainfall events. 展开更多
关键词 excessive rainfall runoff green-grey-blue integrated system emergency response intelligent control optimization framework multi-departmental collaboration climate change flood
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Novel Structural Features of Isoflavone Synthase from Medicago truncatula Shed Light on Its Unique Enzymatic Mechanism
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作者 SHI Chao YE Zhao-Yang +12 位作者 XU Fei DU Xiang-Ning CHEN Zhang-Xin GU Ming-Yue DENG Jie WANG Wei LIU Liang-Yu WANG Mei-Ying SU Xiao-Dong LIU He-Li SHANG Ming-Ying HUANG Li-Xin CHANG Zhen-Zhan 《中国生物化学与分子生物学报》 北大核心 2025年第8期1204-1213,I0003-I0008,共16页
Isoflavones which mainly distributed in leguminous plants have plenty of health benefits.Isoflavone synthase(IFS)is a membrane-associated cytochrome P450 enzyme(CYP450)which carries out the unique aryl-ring migration ... Isoflavones which mainly distributed in leguminous plants have plenty of health benefits.Isoflavone synthase(IFS)is a membrane-associated cytochrome P450 enzyme(CYP450)which carries out the unique aryl-ring migration and hydroxylation.So far,few crystal structures of plant P450s have been obtained.We determined the crystal structure of IFS from Medicago truncatula at 1.9 by MAD method using a selenomethionine substituted crystal and conducted molecular docking and mutagenesis study.The structure of IFS complexed with imidazole exhibits the helix Iα-loop-helix Iβmotif which corresponds to helix I of other P 450s.Compared with structures of common P450s,IFS/imidazole structure contains an extra domain,i.e.,theγ-domain.The structure reveals a homodimer in which theγ-domain of one molecule interacts with theβ-domain of another.The plane of heme group makes an angle of approximately 40°with the helix Iα-loop-helix Iβmotif.Molecular docking combined with mutagenesis study suggested that Trp-128 and Asp-300 might play important roles in substrate binding and recognition.Phe-301,Ser-303 and Gly-305 from the helix Iα-loop-helix Iβmotif may play important roles in the aryl-ring migration.These novel structural features reveal insights into the unique reaction mechanism of IFS and provide a basis for engineering IFS in leguminous crops for health purpose. 展开更多
关键词 cytochrome P450 enzyme(CYP450) isoflavone synthase(IFS) crystal structure HOMODIMER
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