用累积比数模型分析有序数据是有效的,但也存在两方面的问题:其一,数据模型在'有序'的表现上是模糊的;其二,无法对各相邻的类之间作显著性检验。但对这两方面的讨论有时是需要的,比较常见的问题是想要了解在解释变量 X 的作用下...用累积比数模型分析有序数据是有效的,但也存在两方面的问题:其一,数据模型在'有序'的表现上是模糊的;其二,无法对各相邻的类之间作显著性检验。但对这两方面的讨论有时是需要的,比较常见的问题是想要了解在解释变量 X 的作用下,反应变量 Y 在不同相邻类中的变化情况,即所谓的'关节点'问题,如冠心病研究。展开更多
Three breeds of sows were observed to investigate the relationship between Single Nucleotide Polymorphisms(SNPs) in Mu Opioid Receptor(MOR)and stereotypic behaviour,such as,sham-chewing,bar biting and standing sti...Three breeds of sows were observed to investigate the relationship between Single Nucleotide Polymorphisms(SNPs) in Mu Opioid Receptor(MOR)and stereotypic behaviour,such as,sham-chewing,bar biting and standing still in order to better understand the mechanism of stereotypic development of the animals in restrained conditions.MOR exon 2 partial sequences were amplified to analyze single nucleotide polymorphisms by PCR-SSCP.One SNP,a silence mutant was found.A significant difference (P〈0.01)was found in the frequency of genotypes in these 3 breeds where only the BB genotype,which was identical to that published in GenBank,was found in the Duroc breed,while no AA genotype was found in Landrace,3 genotypes AA,BB and AB were found in Yorkshire.The result also indicated that the individuals with AA and AB genotypes tended to be more active in sham-chewing than those with the BB genotype(P〈0.05).The overall results of this study suggested that sham-chewing of sows may be subjected to both genetic control and environmental conditions,but activity level was more likely to be affected by their environment.We can putatively draw the conclusion that MOR gene has effect on the sham-chewing behavioral traits of sow.展开更多
文摘用累积比数模型分析有序数据是有效的,但也存在两方面的问题:其一,数据模型在'有序'的表现上是模糊的;其二,无法对各相邻的类之间作显著性检验。但对这两方面的讨论有时是需要的,比较常见的问题是想要了解在解释变量 X 的作用下,反应变量 Y 在不同相邻类中的变化情况,即所谓的'关节点'问题,如冠心病研究。
基金Supported by National Natural Sciences Foundation of China(39970533)
文摘Three breeds of sows were observed to investigate the relationship between Single Nucleotide Polymorphisms(SNPs) in Mu Opioid Receptor(MOR)and stereotypic behaviour,such as,sham-chewing,bar biting and standing still in order to better understand the mechanism of stereotypic development of the animals in restrained conditions.MOR exon 2 partial sequences were amplified to analyze single nucleotide polymorphisms by PCR-SSCP.One SNP,a silence mutant was found.A significant difference (P〈0.01)was found in the frequency of genotypes in these 3 breeds where only the BB genotype,which was identical to that published in GenBank,was found in the Duroc breed,while no AA genotype was found in Landrace,3 genotypes AA,BB and AB were found in Yorkshire.The result also indicated that the individuals with AA and AB genotypes tended to be more active in sham-chewing than those with the BB genotype(P〈0.05).The overall results of this study suggested that sham-chewing of sows may be subjected to both genetic control and environmental conditions,but activity level was more likely to be affected by their environment.We can putatively draw the conclusion that MOR gene has effect on the sham-chewing behavioral traits of sow.