According to the current situation of repair and supply for valuable spare parts in the weapon equipment of the PLA,using the research results of the repairable spare parts inventory theory,an inventory model of the v...According to the current situation of repair and supply for valuable spare parts in the weapon equipment of the PLA,using the research results of the repairable spare parts inventory theory,an inventory model of the valuable spare parts in three-echelon repair and supply system is established by expanding the classical METRIC model and theory,and the genetic algorithm is utilized to solve the model.In the algorithm,the chromosome representation and initial population production,the crossover and mutation operators are designed.By using an example,a simulation analysis is carried out to verify the model's correctness.展开更多
针对以往船舶备件需求预测精度不高,无法满足船舶综合保障的实际问题,文章建立一种基于改进红狐优化算法(improved red fox optimization,IRFO)的支持向量机回归(support vector regression,SVR)的船舶备件预测模型。为进一步提高红狐...针对以往船舶备件需求预测精度不高,无法满足船舶综合保障的实际问题,文章建立一种基于改进红狐优化算法(improved red fox optimization,IRFO)的支持向量机回归(support vector regression,SVR)的船舶备件预测模型。为进一步提高红狐优化算法(red fox optimization,RFO)的寻优精度,重构其全局搜索公式,并融合精英反向学习策略。采用基准测试函数对IRFO算法进行仿真实验,实验表明,IRFO算法比RFO算法、粒子群算法、灰狼优化算法寻优能力更强,综合性能更优。基于船舶备件历史数据,建立IRFO-SVR船舶备件预测模型,通过对比其他模型的预测结果,表明IRFO-SVR的预测效果更佳。展开更多
Spare parts are critical to scheduled maintenance and fault repair, and can directly affect the readiness and combat capability of equipment. Equipmentrs capacity of carrying spares is influenced by its storage space ...Spare parts are critical to scheduled maintenance and fault repair, and can directly affect the readiness and combat capability of equipment. Equipmentrs capacity of carrying spares is influenced by its storage space and scales, so it is necessary to consider economic factors, e.g. spares cost, as well as non-economic ones, such as spares volume, mass and scale, when optimizing spares configuration. Aiming at this problem, the optimization model based on multi-constraints for carrying spares is built by METRIC theory and system analysis. Through the introduction of Lagrange factors, the spares cost is transformed to shadow price, and the optimization method for carrying spares and the dynamic adjustment policy of Lagrange factors are proposed. The result of a given example is analyzed, and demonstrates that the proposed model can be optimized with all constraints, and the research can provide a new way for carrying spares optimization.展开更多
Objective: To investigate the role of spinal glial cells activation in neuropathic pain in a recently developed spared nerve injury (SNI) animal model by Decosterd and Woolf. Methods: A lesion was made to two of the t...Objective: To investigate the role of spinal glial cells activation in neuropathic pain in a recently developed spared nerve injury (SNI) animal model by Decosterd and Woolf. Methods: A lesion was made to two of the three terminal branches of the sciatic nerve of rats (tibial and common peroneal nerves) leaving the sural nerve intact. Continuous intrathe-cal administration of propentofylline, a glial modulating agent, 1 d before and 5 d after operation, was performed to disrupt spinal cord glia function. The vehicle was intrathecally administrated as control. The paw withdrawal threshold to mechanical stimulation (paw withdrawal mechaical threshold PWMT), body mass and motor function were determined pre- and post-surgery. Results: It produced a prolonged mechanical allodynia in the medial and lateral part of the ipsilateral hind paw in SNL models. The treatment with propentofylline significantly prevented the development of mechanical allodynia located in either medial or lateral plantar surface. Rats in two groups showed normal motor function and body weight increase. Conclusion: SNI model can be applied as a useful method with little variance in searching the mechanism of neuropathic pain. These study suggest that spinal glia activation may contribute to mechanical allodynia induced by SNI.展开更多
Objective:Nephron-sparing surgery(NSS) for small renal masses offers a similar functional and oncological outcome to that of radical surgery.Laparoendoscopic single-site surgery(LESS) emerges as an advanced alternativ...Objective:Nephron-sparing surgery(NSS) for small renal masses offers a similar functional and oncological outcome to that of radical surgery.Laparoendoscopic single-site surgery(LESS) emerges as an advanced alternative for reduced invasiveness and improves cosmesis;LESS is developing quickly and its indications have been expanded,but still in its infancy.The aim of this paper is to report our preliminary experience in transumbilical LESS partial nephrectomy(LESS-PN),so as to assess its utility, safety and efficacy.Methods:From August 2009 to October 2010,3 patients underwent transumbilical LESS-PN via a novel multi-channel TriPort by a single experienced urologist in our institution.Patient demographics,perioperative and follow-up data were prospectively collected and analyzed.Results:All the three procedures were successfully completed.A 5-mm ancillary trocar was utilized in all 3 cases.The mean operative duration was 226.3(210-254 min) with an estimated blood loss of 56.7 ml (20-100 ml).Mean warm ischemia time was 35.7 min(19-48 min).One patient was transfused due to postoperative bleeding. The recovery was uneventful and mean length of postoperative stay was 13 days(12-14 days).At the latest follow-up,all patients remained symptom-free and had normal renal function without evidence of recurrence,and they were delighted for a hidden transumbilical scar.Conclusion:Transumbilical LESS-PN is a feasible and safe procedure albeit extremely technically challenging.Surgical outcomes at a median follow-up of 2 years are promising,while currently it should be reserved for highly selected patients with favorable tumor anatomy and performed by a very experienced laparoscopic surgeon.展开更多
基金Sponsored by the Foundation of National Defense Research(2008-76320)
文摘According to the current situation of repair and supply for valuable spare parts in the weapon equipment of the PLA,using the research results of the repairable spare parts inventory theory,an inventory model of the valuable spare parts in three-echelon repair and supply system is established by expanding the classical METRIC model and theory,and the genetic algorithm is utilized to solve the model.In the algorithm,the chromosome representation and initial population production,the crossover and mutation operators are designed.By using an example,a simulation analysis is carried out to verify the model's correctness.
文摘针对以往船舶备件需求预测精度不高,无法满足船舶综合保障的实际问题,文章建立一种基于改进红狐优化算法(improved red fox optimization,IRFO)的支持向量机回归(support vector regression,SVR)的船舶备件预测模型。为进一步提高红狐优化算法(red fox optimization,RFO)的寻优精度,重构其全局搜索公式,并融合精英反向学习策略。采用基准测试函数对IRFO算法进行仿真实验,实验表明,IRFO算法比RFO算法、粒子群算法、灰狼优化算法寻优能力更强,综合性能更优。基于船舶备件历史数据,建立IRFO-SVR船舶备件预测模型,通过对比其他模型的预测结果,表明IRFO-SVR的预测效果更佳。
基金supported in part by the General Armament Department Pre-research Foundation in 12th FiveYear(No.51304010206)the National Defense Pre-research Project in 13th Five-Year (No.41404050502)
文摘Spare parts are critical to scheduled maintenance and fault repair, and can directly affect the readiness and combat capability of equipment. Equipmentrs capacity of carrying spares is influenced by its storage space and scales, so it is necessary to consider economic factors, e.g. spares cost, as well as non-economic ones, such as spares volume, mass and scale, when optimizing spares configuration. Aiming at this problem, the optimization model based on multi-constraints for carrying spares is built by METRIC theory and system analysis. Through the introduction of Lagrange factors, the spares cost is transformed to shadow price, and the optimization method for carrying spares and the dynamic adjustment policy of Lagrange factors are proposed. The result of a given example is analyzed, and demonstrates that the proposed model can be optimized with all constraints, and the research can provide a new way for carrying spares optimization.
文摘Objective: To investigate the role of spinal glial cells activation in neuropathic pain in a recently developed spared nerve injury (SNI) animal model by Decosterd and Woolf. Methods: A lesion was made to two of the three terminal branches of the sciatic nerve of rats (tibial and common peroneal nerves) leaving the sural nerve intact. Continuous intrathe-cal administration of propentofylline, a glial modulating agent, 1 d before and 5 d after operation, was performed to disrupt spinal cord glia function. The vehicle was intrathecally administrated as control. The paw withdrawal threshold to mechanical stimulation (paw withdrawal mechaical threshold PWMT), body mass and motor function were determined pre- and post-surgery. Results: It produced a prolonged mechanical allodynia in the medial and lateral part of the ipsilateral hind paw in SNL models. The treatment with propentofylline significantly prevented the development of mechanical allodynia located in either medial or lateral plantar surface. Rats in two groups showed normal motor function and body weight increase. Conclusion: SNI model can be applied as a useful method with little variance in searching the mechanism of neuropathic pain. These study suggest that spinal glia activation may contribute to mechanical allodynia induced by SNI.
基金Supported by the Military Major Project for Clinical High-tech and Innovative Technology of China(2010gxjs057)the Municipal Hospitals' Project for Emerging and Frontier Technology of Shanghai(SHDC12010115)the Project for the Key Discipline of Shanghai
文摘Objective:Nephron-sparing surgery(NSS) for small renal masses offers a similar functional and oncological outcome to that of radical surgery.Laparoendoscopic single-site surgery(LESS) emerges as an advanced alternative for reduced invasiveness and improves cosmesis;LESS is developing quickly and its indications have been expanded,but still in its infancy.The aim of this paper is to report our preliminary experience in transumbilical LESS partial nephrectomy(LESS-PN),so as to assess its utility, safety and efficacy.Methods:From August 2009 to October 2010,3 patients underwent transumbilical LESS-PN via a novel multi-channel TriPort by a single experienced urologist in our institution.Patient demographics,perioperative and follow-up data were prospectively collected and analyzed.Results:All the three procedures were successfully completed.A 5-mm ancillary trocar was utilized in all 3 cases.The mean operative duration was 226.3(210-254 min) with an estimated blood loss of 56.7 ml (20-100 ml).Mean warm ischemia time was 35.7 min(19-48 min).One patient was transfused due to postoperative bleeding. The recovery was uneventful and mean length of postoperative stay was 13 days(12-14 days).At the latest follow-up,all patients remained symptom-free and had normal renal function without evidence of recurrence,and they were delighted for a hidden transumbilical scar.Conclusion:Transumbilical LESS-PN is a feasible and safe procedure albeit extremely technically challenging.Surgical outcomes at a median follow-up of 2 years are promising,while currently it should be reserved for highly selected patients with favorable tumor anatomy and performed by a very experienced laparoscopic surgeon.
