The scintiphotos and ultrasonophotos of 186 patients with focal and diffuse diseases of liver were collected and analysed. All the data were get from the in-patients of China-Japan Friendship Hospital. The Sigma 438 t...The scintiphotos and ultrasonophotos of 186 patients with focal and diffuse diseases of liver were collected and analysed. All the data were get from the in-patients of China-Japan Friendship Hospital. The Sigma 438 typedγ camera (USA) was used. Fifteen min after 99mTc-phytate were injected i.v., If any defect region was found, it was recorded as a SOL; the SSA 90A, SAL 77A and SAL 50A US scanners (Japan) were used, if any abnormal echo pattern was found, it was a SOL. Of 134 patients have done both examinations during 7 days, 122 patients had coincident results occupied 91.0%. For detection of SOL, the sensitivity of scintigraphy is 94.1%, specificity is 94.2%, accuracy is 94.8%; the sensitivity of US is 100%, specificity is 89.7%, the accuracy is 95.6%. The hepatic blood flow and blood pool study showed that 104 from 115 patients were coincident (90.4%). The spleen and liver accumulation ratio determination showed that 51 from 64 subjects were coincident (80.0%). The characteristic features of scintigraphy and US graphy were described in hepatoma, hemangioma, cyst abscess and cirrhosis. The advantages of these examinations were discussed and concluded that their procedures are valuable and widely available.展开更多
Objective To evaluate the feasibility of whole body diffusion weighted imaging (DWI) in bone metastasis detection using bone scintigraphy as comparison. Methods Forty-five patients with malignancy history were enrolle...Objective To evaluate the feasibility of whole body diffusion weighted imaging (DWI) in bone metastasis detection using bone scintigraphy as comparison. Methods Forty-five patients with malignancy history were enrolled in our study. All the patients received the whole body DWI and bone scintigraphy scan within 1 week. The magnetic resonance (MR) examination was performed on 3.0T MR scanner using embedded body coil. The images were reviewed separately by two radiologists and two nuclear medicine physicians, who were blinded to the results of the other imaging modality. The sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of the two techniques for detecting bone metastasis were analyzed. Results A total of 181 metastatic lesions in 77 regions of 34 patients were detected by whole body DWI, and 167 metastatic lesions in 76 regions of 31 patients were identified by bone scintigraphy. The patient-based sensitivity and PPV of whole body DWI and bone scintigraphy were similar (89.5% vs. 81.6%, 97.1% vs. 91.2%), whereas, the patient-based specificity and NPV of whole body DWI were obviously higher than those of bone scintigraphy (85.7% vs. 57.1%, 60.0% vs. 36.4%). Ten regions negative in scintigraphy but positive in whole body DWI, mainly located in spine, pelvis, and femur; nine regions only detected by scintigraphy, mainly located in skull, sternum, clavicle, and scapula. The region-based sensitivity and specificity of whole body DWI were slightly higher than those of bone scintigraphy (89.5% vs. 88.4%, 95.6% vs. 87.6%). Conclusion Whole body DWI reveals excellent concordance with bone scintigraphy regarding detection of bone metastasis, and the two techniques are complementary for each other.展开更多
Amyloidosis is a multisystem disease that is characterized by deposition of fibrils in extracellular tissue,which mainly involves the kidney,heart,and autonomic nervous system.Two types of amyloidosis typically infilt...Amyloidosis is a multisystem disease that is characterized by deposition of fibrils in extracellular tissue,which mainly involves the kidney,heart,and autonomic nervous system.Two types of amyloidosis typically infiltrate the heart,including immunoglobulin light-chain(AL)and amyloid transthyretin(ATTR).ATTR is further subdivided into wild-type ATTR and variant ATTR caused by point mutations in the TTR gene.[1]Wild-type ATTR is considered as not uncommon in older patients with heart failure.Recently,a comprehensive set of consensus recommendations for the suspicion and diagnosis of ATTR was published,with particular focus on the combined application of noninvasive methods.[2]We present here a case of wild-type TTR cardiac amyloidosis(ATTRwt-CA),which was diagnosed by noninvasive modalities,and provide an overview of the recommended diagnostic approach of CA.Furthermore,to the best of our knowledge,this is the first Chinese case of ATTRwt-CA reported to date.展开更多
Stress fracture（SF）in military recruits in China was investigated using<sup>99m</sup>Tc-MDP bone scintigraphy in a randomized sample of 432 injured who wereclinically screened from 1060 recruits during b...Stress fracture（SF）in military recruits in China was investigated using<sup>99m</sup>Tc-MDP bone scintigraphy in a randomized sample of 432 injured who wereclinically screened from 1060 recruits during basic training.The relationship between SFand training intensity was discussed.It was shown that the total incidence was 32.5%.There were two peaks during 9 training-weeks:one was in the 2nd week,and the otherin the 7th.Infantry soldiers had a more intensive training and,therefore a higher inci-dence than in artillery and service troops.Although SF was found in most ofweight-bearing bones,tibia was most commonly fractured（67%）.The findings suggestthat SF is a major training-related injury in military recruits and improperly strengthenedtraining can increase the incidence.展开更多
基金The Project was supported by the International Atomic Energy Agency
文摘The scintiphotos and ultrasonophotos of 186 patients with focal and diffuse diseases of liver were collected and analysed. All the data were get from the in-patients of China-Japan Friendship Hospital. The Sigma 438 typedγ camera (USA) was used. Fifteen min after 99mTc-phytate were injected i.v., If any defect region was found, it was recorded as a SOL; the SSA 90A, SAL 77A and SAL 50A US scanners (Japan) were used, if any abnormal echo pattern was found, it was a SOL. Of 134 patients have done both examinations during 7 days, 122 patients had coincident results occupied 91.0%. For detection of SOL, the sensitivity of scintigraphy is 94.1%, specificity is 94.2%, accuracy is 94.8%; the sensitivity of US is 100%, specificity is 89.7%, the accuracy is 95.6%. The hepatic blood flow and blood pool study showed that 104 from 115 patients were coincident (90.4%). The spleen and liver accumulation ratio determination showed that 51 from 64 subjects were coincident (80.0%). The characteristic features of scintigraphy and US graphy were described in hepatoma, hemangioma, cyst abscess and cirrhosis. The advantages of these examinations were discussed and concluded that their procedures are valuable and widely available.
文摘Objective To evaluate the feasibility of whole body diffusion weighted imaging (DWI) in bone metastasis detection using bone scintigraphy as comparison. Methods Forty-five patients with malignancy history were enrolled in our study. All the patients received the whole body DWI and bone scintigraphy scan within 1 week. The magnetic resonance (MR) examination was performed on 3.0T MR scanner using embedded body coil. The images were reviewed separately by two radiologists and two nuclear medicine physicians, who were blinded to the results of the other imaging modality. The sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of the two techniques for detecting bone metastasis were analyzed. Results A total of 181 metastatic lesions in 77 regions of 34 patients were detected by whole body DWI, and 167 metastatic lesions in 76 regions of 31 patients were identified by bone scintigraphy. The patient-based sensitivity and PPV of whole body DWI and bone scintigraphy were similar (89.5% vs. 81.6%, 97.1% vs. 91.2%), whereas, the patient-based specificity and NPV of whole body DWI were obviously higher than those of bone scintigraphy (85.7% vs. 57.1%, 60.0% vs. 36.4%). Ten regions negative in scintigraphy but positive in whole body DWI, mainly located in spine, pelvis, and femur; nine regions only detected by scintigraphy, mainly located in skull, sternum, clavicle, and scapula. The region-based sensitivity and specificity of whole body DWI were slightly higher than those of bone scintigraphy (89.5% vs. 88.4%, 95.6% vs. 87.6%). Conclusion Whole body DWI reveals excellent concordance with bone scintigraphy regarding detection of bone metastasis, and the two techniques are complementary for each other.
基金the National Key Research and Development Program of China(2016YFC0901500).
文摘Amyloidosis is a multisystem disease that is characterized by deposition of fibrils in extracellular tissue,which mainly involves the kidney,heart,and autonomic nervous system.Two types of amyloidosis typically infiltrate the heart,including immunoglobulin light-chain(AL)and amyloid transthyretin(ATTR).ATTR is further subdivided into wild-type ATTR and variant ATTR caused by point mutations in the TTR gene.[1]Wild-type ATTR is considered as not uncommon in older patients with heart failure.Recently,a comprehensive set of consensus recommendations for the suspicion and diagnosis of ATTR was published,with particular focus on the combined application of noninvasive methods.[2]We present here a case of wild-type TTR cardiac amyloidosis(ATTRwt-CA),which was diagnosed by noninvasive modalities,and provide an overview of the recommended diagnostic approach of CA.Furthermore,to the best of our knowledge,this is the first Chinese case of ATTRwt-CA reported to date.
文摘Stress fracture（SF）in military recruits in China was investigated using<sup>99m</sup>Tc-MDP bone scintigraphy in a randomized sample of 432 injured who wereclinically screened from 1060 recruits during basic training.The relationship between SFand training intensity was discussed.It was shown that the total incidence was 32.5%.There were two peaks during 9 training-weeks:one was in the 2nd week,and the otherin the 7th.Infantry soldiers had a more intensive training and,therefore a higher inci-dence than in artillery and service troops.Although SF was found in most ofweight-bearing bones,tibia was most commonly fractured（67%）.The findings suggestthat SF is a major training-related injury in military recruits and improperly strengthenedtraining can increase the incidence.
