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Risk adjustable optimal operation for electricity-hydrogen integrated energy system based on chance constrained goal programming
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作者 ZHOU Xiao-jun HU Jia-ming +1 位作者 LI Chao-jie YANG Chun-hua 《Journal of Central South University》 2025年第6期2224-2238,共15页
The electricity-hydrogen integrated energy system(EH-IES)enables synergistic operation of electricity,heat,and hydrogen subsystems,supporting renewable energy integration and efficient multi-energy utilization in futu... The electricity-hydrogen integrated energy system(EH-IES)enables synergistic operation of electricity,heat,and hydrogen subsystems,supporting renewable energy integration and efficient multi-energy utilization in future low carbon societies.However,uncertainties from renewable energy and load variability threaten system safety and economy.Conventional chance-constrained programming(CCP)ensures reliable operation by limiting risk.However,increasing source-load uncertainties that can render CCP models infeasible and exacerbate operational risks.To address this,this paper proposes a risk-adjustable chance-constrained goal programming(RACCGP)model,integrating CCP and goal programming to balance risk and cost based on system risk assessment.An intelligent nonlinear goal programming method based on the state transition algorithm(STA)is developed,along with an improved discretized step transformation,to handle model nonlinearity and enhance computational efficiency.Experimental results show that the proposed model reduces costs while controlling risk compared to traditional CCP,and the solution method outperforms average sample sampling in efficiency and solution quality. 展开更多
关键词 electricity-hydrogen integrated energy system chance constrained goal programming risk adjustment state transition algorithm
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Research on strategic risk identification method of equipment system development based on system dynamics 被引量:3
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作者 WANG Xinfeng WANG Tao +1 位作者 ZHOU Xin WANG Yanfeng 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2023年第5期1225-1234,共10页
Strategic management of equipment system develop-ment must attach importance to effective strategic risk manage-ment.Aiming at the identification of strategic risk of equipment system development,firstly,the source of... Strategic management of equipment system develop-ment must attach importance to effective strategic risk manage-ment.Aiming at the identification of strategic risk of equipment system development,firstly,the source of strategic risk of equip-ment system development is analyzed and classified.Based on this,a causal loop diagram of strategic risk of equipment sys-tem development based on system dynamics is established.The system dynamics analysis software Vensim PLE is used to carry out the risk influencing factors analysis,risk consequences ana-lysis,risk feedback loop identification and corresponding pre-control measures,and achieves a good risk identification effect. 展开更多
关键词 equipment system development strategy manage-ment strategic risk management risk identification system dynamics loop diagram of causality
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Integrated evaluation system under randomness and fuzziness for groundwater contamination risk assessment in a little town, Central China 被引量:2
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作者 祝慧娜 袁兴中 +4 位作者 梁婕 刘永德 尹娟 江洪炜 黄华军 《Journal of Central South University》 SCIE EI CAS 2014年第3期1044-1050,共7页
An integrated evaluation system under randomness and fuzziness was developed in this work to systematically assess the risk of groundwater contamination in a little town, Central China. In this system, randomness of t... An integrated evaluation system under randomness and fuzziness was developed in this work to systematically assess the risk of groundwater contamination in a little town, Central China. In this system, randomness of the parameters and the fuzziness of the risk were considered simultaneously, and the exceeding standard probability of contamination and human health risk due to the contamination were integrated. The contamination risk was defined as a combination of "vulnerability" and "hazard". To calculate the value of "vulnerability", pollutant concentration was simulated by MODFLOW with random input variables and a new modified health risk assessment(MRA) model was established to analyze the level of "hazard". The limit concentration based on environmental-guideline and health risk due to manganese were systematically examined to obtain the general risk levels through a fuzzy rule base. The "vulnerability" and "hazard" were divided into five categories of "high", "medium-high", "medium", "low-medium" and "low", respectively. Then, "vulnerability" and "hazard" were firstly combined by integrated evaluation. Compared with the other two scenarios under deterministic methods, the risk obtained in the proposed system is higher. This research illustrated that ignoring of uncertainties in evaluation process might underestimate the risk level. 展开更多
关键词 integrated evaluation RANDOMNESS FUZZINESS modified health risk assessment uncertainty MANGANESE
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Health evaluation method for degrading systems subject to dependent competing risks 被引量:3
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作者 ZHAO Shuai MAKIS Viliam +1 位作者 CHEN Shaowei LI Yong 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2018年第2期436-444,共9页
This paper proposes a health evaluation method for degrading systems subject to competing risks of dependent soft and hard failures. To characterize the time-varying degradation rate, the degradation process is determ... This paper proposes a health evaluation method for degrading systems subject to competing risks of dependent soft and hard failures. To characterize the time-varying degradation rate, the degradation process is determined by a non-stationary Gamma process and the soft failure is encountered when it exceeds a predefined critical level. For the hard failure, a Cox’s proportional hazard model is applied to describe the hazard rate of the time to system failure. The dependent relationship is modeled by incorporating the degradation process as a time-varying covariate into the Cox’s proportional hazard model. To facilitate the health characteristics evaluation, a discretization technique is applied both to the degradation process and the monitoring time.All health characteristics can be obtained in the explicit form using the transition probability matrix, which is computationally attractive for practical applications. Finally, a numerical analysis is carried out to show the effectiveness and the performance of the proposed health evaluation method. 展开更多
关键词 competing risk conditional mean residual life health evaluation non-stationary Gamma process proportional hazards model
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Risk based security assessment of power system using generalized regression neural network with feature extraction 被引量:2
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作者 M. Marsadek A. Mohamed 《Journal of Central South University》 SCIE EI CAS 2013年第2期466-479,共14页
A comprehensive risk based security assessment which includes low voltage, line overload and voltage collapse was presented using a relatively new neural network technique called as the generalized regression neural n... A comprehensive risk based security assessment which includes low voltage, line overload and voltage collapse was presented using a relatively new neural network technique called as the generalized regression neural network (GRNN) with incorporation of feature extraction method using principle component analysis. In the risk based security assessment formulation, the failure rate associated to weather condition of each line was used to compute the probability of line outage for a given weather condition and the extent of security violation was represented by a severity function. For low voltage and line overload, continuous severity function was considered due to its ability to zoom in into the effect of near violating contingency. New severity function for voltage collapse using the voltage collapse prediction index was proposed. To reduce the computational burden, a new contingency screening method was proposed using the risk factor so as to select the critical line outages. The risk based security assessment method using GRNN was implemented on a large scale 87-bus power system and the results show that the risk prediction results obtained using GRNN with the incorporation of principal component analysis give better performance in terms of accuracy. 展开更多
关键词 generalized regression neural network line overload low voltage principle component analysis risk index voltagecollapse
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Real-time lane departure warning system based on principal component analysis of grayscale distribution and risk evaluation model 被引量:4
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作者 张伟伟 宋晓琳 张桂香 《Journal of Central South University》 SCIE EI CAS 2014年第4期1633-1642,共10页
A technology for unintended lane departure warning was proposed. As crucial information, lane boundaries were detected based on principal component analysis of grayscale distribution in search bars of given number and... A technology for unintended lane departure warning was proposed. As crucial information, lane boundaries were detected based on principal component analysis of grayscale distribution in search bars of given number and then each search bar was tracked using Kalman filter between frames. The lane detection performance was evaluated and demonstrated in ways of receiver operating characteristic, dice similarity coefficient and real-time performance. For lane departure detection, a lane departure risk evaluation model based on lasting time and frequency was effectively executed on the ARM-based platform. Experimental results indicate that the algorithm generates satisfactory lane detection results under different traffic and lighting conditions, and the proposed warning mechanism sends effective warning signals, avoiding most false warning. 展开更多
关键词 lane departure warning system lane detection lane tracking principal component analysis risk evaluation model ARM-based real-time system
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Replacement Strategy for Aged Transformers Based on Condition Monitoring and System Risk 被引量:1
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作者 Dabo ZHANG Wenyuan LI Xiaofu XIONG 《电力系统自动化》 EI CSCD 北大核心 2013年第17期64-71,共8页
关键词 系统风险 替换策略 状态监测 变形金刚 老年 老化故障 风险评估 变压器
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Study on risk measurement about ammunition-rocket system
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作者 GuXiaohui ZhaoYoushou 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2005年第1期228-232,共5页
Modern ammunition-rocket system is a complicated multidisciplinary system. During its development, undetermined factors will bring many risks. This paper elaborates the importance of risk analysis approach to ammuniti... Modern ammunition-rocket system is a complicated multidisciplinary system. During its development, undetermined factors will bring many risks. This paper elaborates the importance of risk analysis approach to ammunition-rocket system development and analyses various methods of risk analysis and estimation. Combined with practical situation of weapon system development, the risk measurement function with characteristics of risk preference is given provided that the risk preference characteristic of behavior maker is risk neutral of fixed constant. The development risk analysis based on risk measurement function enables effective risk decision to be made on the basis of quantified risk. Taking anti-helicopter intelligent mine warhead as an example, the paper verifies the efficiency of the method and shows that it has a scientific and practical value. 展开更多
关键词 risk analysis risk function ammunition-rocket system.
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Construction of Public Security Risk Governance System under the View of Risk Society Theory
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作者 Ding Donghan 《学术界》 CSSCI 北大核心 2020年第6期193-201,共9页
With the development of economy,China has to fight against the increasing public security risk. The theory of risk society points out that the traditional system of hierarchical management should be transformed into t... With the development of economy,China has to fight against the increasing public security risk. The theory of risk society points out that the traditional system of hierarchical management should be transformed into the governance system led by government and participated in by multiple parties to avoid and reduce risk in modern society. In order to achieve modernization of the national governance system and capacity,we have to deal with these two important subjects,that is,what can we learn from the Western risk society theory and how to establish a scientific and efficient public security risk management system based on the characteristics of modern public security risk. 展开更多
关键词 risk society theory of risk society public security risk
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Some studies on stochastic optimization based quantitative risk management
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作者 HU Zhaolin 《运筹学学报(中英文)》 北大核心 2025年第3期135-159,共25页
Risk management often plays an important role in decision making un-der uncertainty.In quantitative risk management,assessing and optimizing risk metrics requires eficient computing techniques and reliable theoretical... Risk management often plays an important role in decision making un-der uncertainty.In quantitative risk management,assessing and optimizing risk metrics requires eficient computing techniques and reliable theoretical guarantees.In this pa-per,we introduce several topics on quantitative risk management and review some of the recent studies and advancements on the topics.We consider several risk metrics and study decision models that involve the metrics,with a main focus on the related com-puting techniques and theoretical properties.We show that stochastic optimization,as a powerful tool,can be leveraged to effectively address these problems. 展开更多
关键词 stochastic optimization quantitative risk management risk measure computing technique statistical property
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Prediction Method of Polar Navigation Window Period Based on Risk Evaluation
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作者 JIANG Jia−qi SHI Gui−jie WANG De−yu 《船舶力学》 北大核心 2025年第6期986-999,共14页
With the increase of international trade activities and the gradual melting of the polar ice cap,the importance of the Arctic route for marine transportation has been emphasized.Prediction of the polar navigation wind... With the increase of international trade activities and the gradual melting of the polar ice cap,the importance of the Arctic route for marine transportation has been emphasized.Prediction of the polar navigation window period is crucial for navigating in the Arctic route,which is of great significance to the selection of the route and the optimization of navigation.This paper introduces the establishment of a risk index system,determination of risk index weight,establishment of a risk evaluation model,and prediction algorithm for the window period.In addition,data sources of both environmental factors and ship factors are introducted,and their shortcomings are analyzed,followed by introduction of various methods involved in window prediction and analysis of their advantages and disadvantages.The quantitative risk evaluation and window period algorithm can provide a reference for the research of polar navigation window period prediction. 展开更多
关键词 window period risk evaluation polar navigation risk index
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Finite-Time Expected Present Value of Operating Costs until Ruin in a Two-Dimensional Risk Model with Periodic Observation
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作者 TENG Ye XIE Jiayi ZHANG Zhimin 《应用概率统计》 北大核心 2025年第5期748-765,共18页
This paper investigates ruin,capital injection,and dividends for a two-dimensional risk model.The model posits that surplus levels of insurance companies are governed by a perturbed composite Poisson risk model.This m... This paper investigates ruin,capital injection,and dividends for a two-dimensional risk model.The model posits that surplus levels of insurance companies are governed by a perturbed composite Poisson risk model.This model introduces a dependence between the two surplus levels,present in both the associated perturbations and the claims resulting from common shocks.Critical levels of capital injection and dividends are established for each of the two risks.The surplus levels are observed discretely at fixed intervals,guiding decisions on capital injection,dividends,and ruin at these junctures.This study employs a two-dimensional Fourier cosine series expansion method to approximate the finite time expected discounted operating cost until ruin.The ensuing approximation error is also quantified.The validity and accuracy of the method are corroborated through numerical examples.Furthermore,the research delves into the optimal capital allocation problem. 展开更多
关键词 two-dimensional risk model Fourier cosine expansion capital injection DIVIDEND
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Construction of CD8^(+)T cell-associated Risk Model in Hepatocellular Carcinoma Based on Bulk and Single-cell RNA-seq Data
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作者 ZHANG Xin-Tong ZHU Jian-Jun +10 位作者 WU Jin WU Hao LU Fan ZHANG Wen-Tao CHANG Jing-Jia TANG Ting OU Zhi-Gao JIA Feng-Feng LI Li YU Peng-Fei LIU Ming 《中国生物化学与分子生物学报》 北大核心 2025年第10期1511-1528,共18页
Hepatocellular carcinoma(HCC),which is essentially primary liver cancer,is closely related to CD8^(+)T cell immune infiltration and immune suppression.We constructed a CD8^(+)T cells related risk score model to predic... Hepatocellular carcinoma(HCC),which is essentially primary liver cancer,is closely related to CD8^(+)T cell immune infiltration and immune suppression.We constructed a CD8^(+)T cells related risk score model to predict the prognosis of HCC patients and provided therapeutic guidance based on the risk score.Using integrated bulk RNA sequencing(RNA-seq)and single-cell RNA sequencing(scRNA-seq)datasets,we identified stable CD8^(+)T cell signatures.Based on these signatures,a 3-gene risk score model,comprised of KLRB1,RGS 2,and TNFRSF1B was constructed.The risk score model was well validated through an independent external validation cohort.We divided patients into high-risk and low-risk groups according to the risk score and compared the differences in immune microenvironment between these two groups.Compared with low-risk patients,high-risk patients have higher M2-type macrophage content(P<0.0001)and lower CD8^(+)T cells infiltration(P<0.0001).High-risk patients predict worse response to immunotherapy treatment than low-risk patients(P<0.01).Drug sensitivity analysis shows that PI3K-β inhibitor AZD6482 and TGFβRII inhibitor SB505124 may be suitable therapies for high-risk patients,while the IGF-1R inhibitor BMS-754807 or the novel pyrimidine-based anti-tumor metabolic drug Gemcitabine could be potential therapeutic choices for low-risk patients.Moreover,expression of these 3-gene model was verified by immunohistochemistry.In summary,the establishment and validation of a CD8^(+)T cell-derived risk model can more accurately predict the prognosis of HCC patients and guide the construction of personalized treatment plans. 展开更多
关键词 hepatocellular carcinoma(HCC) CD8^(+)T cell risk scoring model tumor immunity drug sensitivity
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Risk Assessment Framework and Algorithm of Power Systems Based on the Partitioned Multi-objective Risk Method 被引量:11
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作者 XIE Shaoyu WANG Xiuli WANG Xifan 《中国电机工程学报》 EI CSCD 北大核心 2011年第34期I0005-I0005,7,共1页
针对平均风险指标无法区分高损失-低概率事件及低损失-高概率事件的缺点,提出了电力系统的分割多目标风险分析框架。该框架将电力系统的风险状态细分为低损失、中等损失和高损失3个风险范围,并提出3个损失范围条件风险函数和条件风险概... 针对平均风险指标无法区分高损失-低概率事件及低损失-高概率事件的缺点,提出了电力系统的分割多目标风险分析框架。该框架将电力系统的风险状态细分为低损失、中等损失和高损失3个风险范围,并提出3个损失范围条件风险函数和条件风险概率的概念。采用经典的容量停运表模型,建立了这些条件期望指标的计算方法。对IEEE-RTS及TH-RTS2000系统进行了分割多目标风险评估,研究不同负荷水平下系统风险在3个损失范围的分布及转移情况,并分析损失分割点对系统风险的影响。通过分割多目标风险分析,风险分析者和决策者可以权衡系统的平均风险以及高、中、低损失范围的条件期望风险,从而对系统的风险状况有一个全面和深入的了解。 展开更多
关键词 英文摘要 内容介绍 编辑工作 期刊
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基于修正RISKE模型的重庆岩溶地区地下水脆弱性评价 被引量:25
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作者 魏兴萍 蒲俊兵 赵纯勇 《生态学报》 CAS CSCD 北大核心 2014年第3期589-596,共8页
岩溶地下水脆弱性评价是保护、管理和利用岩溶地下水的基础与有效方法。我国西南岩溶区绝大多数地区由于缺少应有的地下水保护带,地下水比较容易受污染。运用修正的RISKE模型,对重庆岩溶地区地下水进行脆弱性评价。结果表明:岩溶在4个... 岩溶地下水脆弱性评价是保护、管理和利用岩溶地下水的基础与有效方法。我国西南岩溶区绝大多数地区由于缺少应有的地下水保护带,地下水比较容易受污染。运用修正的RISKE模型,对重庆岩溶地区地下水进行脆弱性评价。结果表明:岩溶在4个地区所占面积从高到低依次为渝东北(43.14%)、渝东南(42.82%)、渝东(9.82%)、渝西地区(4.22%)。重庆岩溶地区地下水脆弱性中度以上,面积比例由高到低依次为渝东南(33.29%)、渝东北(29.21%)、渝东(6.68%)、渝西地区(2.37%)。地下水水质检测由差到好依次为渝东南、渝东北、渝西和渝东地区。地下水脆弱性在空间分布上的特征不仅显示了岩性、土壤、落水洞、岩溶裂隙等自然特征对其脆弱性的影响,同时也反映了人类活动对地下水的影响。因此在自然条件无法改变的情况下,控制人类活动对地下水的污染就显得尤为重要。 展开更多
关键词 riskE模型 重庆岩溶地区 地下水 脆弱性评价
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RISK信号通路在1-磷酸鞘氨醇后适应减轻心肌细胞缺氧/复氧损伤中的作用 被引量:9
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作者 王雨晴 吴艳娜 +4 位作者 李欣 尹永强 康毅 娄建石 温克 《中国药理学通报》 CAS CSCD 北大核心 2015年第2期181-185,共5页
目的研究再灌注损伤挽救激酶(reperfusion injury salvage kinase,RISK)信号通路在1-磷酸鞘氨醇(sphingosine-1-phosphate,S1P)后适应减轻H9c2心肌细胞缺氧/复氧损伤中的作用。方法将H9c2细胞随机分为7组,即(1)正常对照组(C);(2)缺氧/... 目的研究再灌注损伤挽救激酶(reperfusion injury salvage kinase,RISK)信号通路在1-磷酸鞘氨醇(sphingosine-1-phosphate,S1P)后适应减轻H9c2心肌细胞缺氧/复氧损伤中的作用。方法将H9c2细胞随机分为7组,即(1)正常对照组(C);(2)缺氧/复氧组(H/R);(3)S1P组;(4)S1P+LY294002组(S1P+LY);(5)LY组;(6)S1P+PD98059组(S1P+PD);(7)PD组。采用MTT法测定各组细胞存活率;比色法测定丙二醛(MDA)含量、总超氧化物歧化酶(TSOD)和锰超氧化物歧化酶(Mn-SOD)活力;采用激光共聚焦显微镜技术检测细胞内游离钙离子浓度变化;流式细胞仪检测心肌细胞凋亡率;Western blot法测定Akt和ERK1/2蛋白的磷酸化水平。结果与H/R组比较,S1P组可明显增加H9c2细胞缺氧/复氧损伤后细胞存活率及凋亡率,增加TSOD及Mn-SOD活力,降低MDA含量,降低钙离子浓度,增加Akt和ERK1/2磷酸化水平,而PI3K/Akt信号通路阻断剂LY294002或ERK1/2阻断剂PD98059可阻断S1P对H9c2的上述作用。结论 S1P能够减轻H9c2细胞缺氧/复氧损伤,加入PI3K/Akt抑制剂LY294002和ERK1/2抑制剂PD98059均使S1P的保护作用被取消,表明S1P通过RISK信号通路发挥抗H9c2细胞缺氧/复氧损伤作用。 展开更多
关键词 S1P 缺氧/复氧 H9C2细胞 PI3K/Akt ERK1/2 risk
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RISK信号通路在β_2-肾上腺素受体激动剂Clenbuterol减轻心肌细胞缺氧/复氧损伤中的作用 被引量:5
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作者 张秋芳 谭艳 +5 位作者 汪选斌 潘龙瑞 李洪亮 刘慧 向继洲 付琴 《中国药理学通报》 CAS CSCD 北大核心 2015年第10期1368-1374,共7页
目的研究β2-肾上腺素受体激动剂clenbuterol对原代培养的心肌细胞缺氧/复氧损伤的作用及其是否与激活再灌注损伤挽救激酶(reperfusion injury salvage kinase,RISK)信号通路有关。方法将原代培养的新生Wistar大鼠乳鼠心肌细胞分为8组,... 目的研究β2-肾上腺素受体激动剂clenbuterol对原代培养的心肌细胞缺氧/复氧损伤的作用及其是否与激活再灌注损伤挽救激酶(reperfusion injury salvage kinase,RISK)信号通路有关。方法将原代培养的新生Wistar大鼠乳鼠心肌细胞分为8组,1正常培养组;2缺氧/复氧(A/R)组;3clenbuterol(1μmol·L-1)+A/R;4ICI118,551(10μmol·L-1)+clenbuterol(1μmol·L-1)+A/R组;5美托洛尔metoprolol(10μmol·L-1)+clenbuterol(1μmol·L-1)+A/R组;6 metoprolol(10μmol·L-1)+A/R组;7 PD98059(20μmol·L-1)+clenbuterol(1μmol·L-1)+A/R组;8LY294002(10μmol·L-1)+clenbuterol(1μmol·L-1)+A/R组。采用MTT法测定各组细胞存活率;比色法检测心肌细胞培养液的乳酸脱氢酶(LDH)含量;Hoechst 33342荧光染色法检测细胞凋亡率;分子探针DCFH-DA检测细胞内活性氧的水平;Western blot检测心肌细胞缺氧/复氧后ERK及p-ERK1/2蛋白的表达水平。结果与A/R组比较,clenbuterol+A/R组明显增高细胞存活率,降低LDH含量,降低细胞凋亡率,ROS产生减少,p-ERK1/2蛋白表达水平增高,而选择性β2受体阻断剂ICI 118,551可取消clenbuterol的上述作用,β1受体阻断剂Metoprolol对clenbuterol的作用无影响,PI3K抑制剂LY294002和ERK1/2抑制剂PD98059可阻断clenbuterol对心肌细胞缺氧/复氧损伤的保护作用。结论clenbuterol能够减轻心肌细胞缺氧/复氧损伤,加入选择性β2受体阻断剂ICI 118,551,PI3K抑制剂LY294002和ERK抑制剂PD98059均使clenbuterol的保护作用取消,表明clenbuterol可通过激动β2肾上腺素受体,激活RISK信号通路发挥抗心肌细胞缺氧/复氧损伤的作用。 展开更多
关键词 CLENBUTEROL 缺氧/复氧 心肌细胞 磷酸化ERK PI3K REPERFUSION injury SALVAGE kinase(risk)
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运用@risk软件评价红脂大小蠹风险初探 被引量:8
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作者 汤宛地 石娟 骆有庆 《中国森林病虫》 北大核心 2008年第4期7-9,14,共4页
参照国际上有害生物风险分析方法,应用新推出的@risk软件对红脂大小蠹Dendroctonusvalens LeConte进行了风险性评价,表明红脂大小蠹属于高度危险的有害生物。用@risk软件对条件影响因子的敏感性分析表明,在所有评判指标中,潜在危害性及... 参照国际上有害生物风险分析方法,应用新推出的@risk软件对红脂大小蠹Dendroctonusvalens LeConte进行了风险性评价,表明红脂大小蠹属于高度危险的有害生物。用@risk软件对条件影响因子的敏感性分析表明,在所有评判指标中,潜在危害性及国内已分布区域这两项指标对红脂大小蠹在我国造成的巨大风险贡献度最高,分别为0.501和0.425。 展开更多
关键词 红脂大小蠹 风险性评价 risk软件
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基于Credit Risk+模型的互联网金融信用风险估计 被引量:6
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作者 李琦 曹国华 《统计与决策》 CSSCI 北大核心 2015年第19期164-166,共3页
文章基于Credit Risk+模型,使用互联网信贷平台四个行业的贷款数据,在不同置信水平下,对互联网金融的信用风险水平进行比较分析。结果表明,行业风险因子间协方差相等时,复合伽玛Credit Risk+模型和多元系统风险Credit Risk+模型计算结... 文章基于Credit Risk+模型,使用互联网信贷平台四个行业的贷款数据,在不同置信水平下,对互联网金融的信用风险水平进行比较分析。结果表明,行业风险因子间协方差相等时,复合伽玛Credit Risk+模型和多元系统风险Credit Risk+模型计算结果几乎一致,与CSFB Credit Risk+模型和两阶段Credit Risk+模型相比能更好地反映贷款组合的非预期损失。行业风险因子间协方差不等时,多元系统风险Credit Risk+模型能克服其他Credit Risk+模型的缺陷,综合考量系统风险和行业风险的影响,能更好地估计贷款组合的信用风险水平。 展开更多
关键词 互联网金融 信贷平台 信用风险 CREDIT risk+模型
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RISK信号转导通路与肾缺血后处理的心肌保护作用 被引量:3
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作者 石磊 蔡尚郎 +1 位作者 刘松 张文忠 《中国心血管杂志》 2007年第1期2-4,45,共4页
目的通过在体兔心肌缺血再灌注模型,研究再灌注损伤补救酶(RISK)信号转导通路是否参与肾缺血后处理对急性心肌缺血再灌注损伤的保护作用。方法32只兔随机分为4组,每组8只。对照组:结扎冠状动脉前降支1h,再灌注5h。实验A组于再灌注同时... 目的通过在体兔心肌缺血再灌注模型,研究再灌注损伤补救酶(RISK)信号转导通路是否参与肾缺血后处理对急性心肌缺血再灌注损伤的保护作用。方法32只兔随机分为4组,每组8只。对照组:结扎冠状动脉前降支1h,再灌注5h。实验A组于再灌注同时对左侧肾动脉行结扎30s、开通30s的3次反复循环,余同对照组;实验B组于再灌注15min后对左侧肾动脉行结扎30s、开通30s的3次反复循环,余同对照组;药物组于再灌注前5min耳缘静脉注射磷脂酰肌醇3激酶(PI3K)抑制剂LY294002(0.3mg/kg),余同实验A组。分别于再灌注3h、再灌注5h取兔血,测定各组血超氧化物歧化酶(SOD)和丙二醛(MDA)的水平。实验终末,取结扎血管支配部位心肌进行免疫组化处理,观察心肌组织蛋白激酶B(Akt)和内皮一氧化氮合酶(eNOS)含量以及心肌组织结构的变化。结果实验A组血SOD含量高于其它组(P<0.01),MDA含量低于其它组(P<0.01),实验A组心肌组织Akt和eNOS含量明显高于其它组(P<0.01);其余组间各项观察指标无显著差异。结论RISK信号转导通路参与肾缺血后处理对急性心肌缺血再灌注损伤的保护作用;肾缺血后处理必须在心肌再灌注后数分钟内立刻进行才能发挥其心肌保护作用。 展开更多
关键词 心肌 缺血后处理 risk信号转导通路 再灌注损伤
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