The nanoparticles of polylactide (PLA) and poly(lactide-co-glycolide) (PLGA) were prepared by the bi-nary organic solvent diffusion method. The yield, particle size and size distribution of these nanoparticles wereeva...The nanoparticles of polylactide (PLA) and poly(lactide-co-glycolide) (PLGA) were prepared by the bi-nary organic solvent diffusion method. The yield, particle size and size distribution of these nanoparticles wereevaluated. The yield of nanoparticles prepared by this method is over 90%, and the average size of the nanoparticlesis between 130-180 nm. In order to clarify the effect of the organic solvent used in the system on nanoparticle yieldand size, the cloud points of PLA and PLGA were examined by cloud point titration. The results indicate that theyields of nanoparticles increase with the increase of ethanol in the acetone solution and attain the maximum at thecloud point of ethanol, while the size of nanoparticles decreases with the increase of ethanol in the acetone solutionand attains the minimum at the cloud point of ethanol. The optimal composition ratio of binary organic solvents coin-cides to that near the cloud point and the optimal condition of binary organic solvents can be predicted.展开更多
研究自然阴干、自然晒干、热风干燥(hot air drying,HD)和真空冷冻干燥(vacuum freeze drying,VFD)对藤椒品质和风味物质的影响。结果表明,VFD处理后藤椒在色泽、山椒素含量等品质上均优于其他3种干燥方式;HD处理后的水分含量结果稍高...研究自然阴干、自然晒干、热风干燥(hot air drying,HD)和真空冷冻干燥(vacuum freeze drying,VFD)对藤椒品质和风味物质的影响。结果表明,VFD处理后藤椒在色泽、山椒素含量等品质上均优于其他3种干燥方式;HD处理后的水分含量结果稍高于另外3种处理方式;在所有干燥方式的藤椒中,HD处理后的风味物质种类最多,有38种,而VFD处理后的藤椒的风味物质含量最高,为2235.407 mg/mL;并且根据风味物质建立偏最小二乘判别分析模型,计算变量投影重要性值,筛选出藤椒受不同干燥方式影响显著的22种关键风味差异物质,分别是松油醇、桧酮、4-萜烯醇、α-松油醇等烯醇酮类物质。根据研究结果综合考量VFD在干燥过程中对鲜藤椒的色泽、水分含量和风味物质保留方面都有较好的结果。该研究结果可为鲜藤椒干燥技术的选择和应用提供数据支持。展开更多
基金Project ( 2001AA218011) supported by the National High Technology Development "863" Program of China
文摘The nanoparticles of polylactide (PLA) and poly(lactide-co-glycolide) (PLGA) were prepared by the bi-nary organic solvent diffusion method. The yield, particle size and size distribution of these nanoparticles wereevaluated. The yield of nanoparticles prepared by this method is over 90%, and the average size of the nanoparticlesis between 130-180 nm. In order to clarify the effect of the organic solvent used in the system on nanoparticle yieldand size, the cloud points of PLA and PLGA were examined by cloud point titration. The results indicate that theyields of nanoparticles increase with the increase of ethanol in the acetone solution and attain the maximum at thecloud point of ethanol, while the size of nanoparticles decreases with the increase of ethanol in the acetone solutionand attains the minimum at the cloud point of ethanol. The optimal composition ratio of binary organic solvents coin-cides to that near the cloud point and the optimal condition of binary organic solvents can be predicted.
