Brain functional networks model the brain's ability to exchange information across different regions,aiding in the understanding of the cognitive process of human visual attention during target searching,thereby c...Brain functional networks model the brain's ability to exchange information across different regions,aiding in the understanding of the cognitive process of human visual attention during target searching,thereby contributing to the advancement of camouflage evaluation.In this study,images with various camouflage effects were presented to observers to generate electroencephalography(EEG)signals,which were then used to construct a brain functional network.The topological parameters of the network were subsequently extracted and input into a machine learning model for training.The results indicate that most of the classifiers achieved accuracy rates exceeding 70%.Specifically,the Logistic algorithm achieved an accuracy of 81.67%.Therefore,it is possible to predict target camouflage effectiveness with high accuracy without the need to calculate discovery probability.The proposed method fully considers the aspects of human visual and cognitive processes,overcomes the subjectivity of human interpretation,and achieves stable and reliable accuracy.展开更多
Objective The aim of this study was to determine the effect of successful coronary revascularisation on left ventricular diastolic function.Methods We consecutively studied the diastolic function by Doppler echocardio...Objective The aim of this study was to determine the effect of successful coronary revascularisation on left ventricular diastolic function.Methods We consecutively studied the diastolic function by Doppler echocardiography in 125 patients with one vessel disease before and 48 hours after selective coronary angioplasty. The following parameters of left ventricular diastolic function were evaluated: peak early (VE, m/s) and peak late diastolic (VA, m/s) flow velocity, E/A ratio, acceleration time (AT, ms), deceleration time (DT, ms) and isovolumetric relaxation time (IVRT, ms). Ejection fraction (EF; %) was determined and used to characterise systolic left ventricular function. Results All of the patients were initially successful treated with coronary angioplasty (residual stenosis <40% ). In 98 patients( 78.4% ) stents were used to improve an inadequate result after coronary angioplasty. Both patient groups (27 patients with coronary angioplasty and 98 patients with combined coronary angioplasty and stent implantation) showed no relevant differences concerning sex, age, atherosclerotic risk factors, exercise capacity and results of exercise electrocardiography. All patients who underwent stent implantation showed an early improvement of left ventricular diastolic function 48 hours after revascularisation. Surprisingly there was no significant short term improvement (48 hours) of diastolic function in patients with initially successful angioplasty.Conclusions We suppose that stent implantation might normalize coronary blood flow faster than that of coronary balloon angioplasty.展开更多
This paper provides a review of methods of assessing a fragmentation weapon’s effectiveness against a point target or an area target with keeping the focus on the necessity of using the Carleton damage function with ...This paper provides a review of methods of assessing a fragmentation weapon’s effectiveness against a point target or an area target with keeping the focus on the necessity of using the Carleton damage function with the correct shape factor.First,cookie-cutter damage functions are redefined to preserve the shape factor of and to have the same lethal area as the corresponding Carleton damage function.Then,closed-form solutions of the effectiveness methods are obtained by using those cookie-cutter damage functions and the Carleton damage function.Finally,the closed-form solutions are applied to calculate the probability of damaging a point target and the expected fractional damage to an area target for several attack scenarios by using cookie-cutter damage functions and the Carleton damage functions with different shape factors.The comparison of the calculation results shows that using cookie-cutter damage functions or the Carleton damage function with a wrong shape factor results in quite significant differences from using the original Carleton damage function with a correct shape factor when weapon’s delivery error deviations are less than or comparable to the lengths of the lethal area and the aim point is far from a target.The effectiveness methods improved in this paper will be useful for mission planning utilizing the precision-guided munitions in circumstances where the collateral damage should be reduced.展开更多
Germplasm effect reflects the quantitative relation between production ability of germplasm elements and yield （quality） of a certain crop, which can be shown by mathematic function, namely, germplasm effect functio...Germplasm effect reflects the quantitative relation between production ability of germplasm elements and yield （quality） of a certain crop, which can be shown by mathematic function, namely, germplasm effect function. Germplasm effect of a crop variety is an aggregation of many effective factors, and is restrained by different effective factors; constant increase of any one effect of germplasm elements would lead to law of effect decline, therefore, possible modes of transgenic crops effect function were deduced according to the law of effect decline. The possible modes of single transgenic germplasm effect function and multi-transgenic germplasm effect regression equation were discussed, and the characteristics of germplasm effect regression equation were analyzed in this paper.展开更多
The spin caloritronic properties of the Janus VSTe monolayer were investigated using density functional theory(DFT)and the non-equilibrium Green’s function(NEGF)method,implemented in the Atomistix Toolkit(ATK)package...The spin caloritronic properties of the Janus VSTe monolayer were investigated using density functional theory(DFT)and the non-equilibrium Green’s function(NEGF)method,implemented in the Atomistix Toolkit(ATK)package.Our study revealed significant spin-splitting within the Janus VSTe monolayer,which induced spin currents under a temperature gradient across the device.By applying a 1%tensile strain,the Janus VSTe monolayer exhibited a perfect thermal spin filtering effect(SFE),with the spin-up current nearly suppressed to zero.Both the unstrained and strained Janus VSTe monolayers demonstrated excellent spin caloritronic properties,with spin figures of merit of 10.915 and 8.432 at an average temperature of 100 K,respectively.Notably,these properties were found to be sensitive to temperature,performing optimally at lower temperatures.These results suggest a promising avenue for designing spin caloritronic devices aimed at efficient waste heat recovery.展开更多
目的观察咳喘镇定汤在小儿咳嗽变异性哮喘治疗中的作用及对患儿嗜酸性粒细胞计数(eosinophil count,EOS)、白介素-23(interleukin-23,IL-23)/辅助性T细胞17(helper T cells17,Th17)轴的影响。方法选取2020年8月—2023年2月收治的小儿咳...目的观察咳喘镇定汤在小儿咳嗽变异性哮喘治疗中的作用及对患儿嗜酸性粒细胞计数(eosinophil count,EOS)、白介素-23(interleukin-23,IL-23)/辅助性T细胞17(helper T cells17,Th17)轴的影响。方法选取2020年8月—2023年2月收治的小儿咳嗽变异性哮喘患儿104例,将患儿采用简单随机法分为两组。常规组给予止咳化痰、抗炎、平喘等常规治疗,咳喘镇定汤组在常规组基础上采用咳喘镇定汤辅助治疗。检测组间及组内T淋巴亚群、EOS、巨噬细胞炎症蛋白-1α(macrophage inflammatory protein-1α,MIP-1α)、Clara细胞分泌蛋白16(clara cell secreted protein 16,CC-16)、嗜酸细胞活化趋化因子(Eotaxin)、IL-23/Th17轴、小气道功能水平。评估组间及组内咳嗽症状评分、中医证候评分差异。统计组间疗效和不良反应。结果治疗前T淋巴亚群、CC-16、Eotaxin等差异无统计学意义(P>0.05)。两组治疗后CD_(8)^(+)、EOS、MIP-1α、Eotaxin降低,CC-16、CD_(4)^(+)、CD_(4)^(+)/CD_(8)^(+)升高,咳喘镇定汤组治疗后CD_(8)^(+)、EOS、MIP-1α、Eotaxin低于常规组,CC-16、CD_(4)^(+)、CD_(4)^(+)/CD_(8)^(+)高于常规组(P<0.05)。治疗前比较IL-23/Th17轴差异无统计学意义(P>0.05)。两组治疗后IL-23、Th17、白介素-17(interleukin-17,IL-17)降低,咳喘镇定汤组治疗后IL-23/Th17轴低于常规组(P<0.05)。治疗前相关评分无差异(P>0.05)。两组治疗后咳嗽症状评分、中医证候评分降低,咳喘镇定汤组治疗后咳嗽症状评分、中医症候评分低于常规组(P<0.05)。治疗前小气道功能无差异(P>0.05)。两组治疗后小气道功能升高,咳喘镇定汤组治疗后小气道功能高于常规组(P<0.05)。咳喘镇定汤组治愈13例,显效和有效共35例,总有效率92.31%高于常规组,差异有统计学意义(P<0.05)。结论咳喘镇定汤可通过调控小儿咳嗽变异性哮喘患儿IL-23/Th17轴,改善T淋巴亚群和小气道功能,减轻咳嗽症状,提高疗效。展开更多
目的观察黄芪多糖注射液联合调强适形放疗治疗中晚期宫颈癌效果。方法研究共计纳入82例中晚期宫颈癌患者,采取随机数字表法将患者分为两组,分别为放疗组及中成药组,每组41例,入组患者均接受常规化疗治疗,放疗组同时接受调强适形放疗治疗...目的观察黄芪多糖注射液联合调强适形放疗治疗中晚期宫颈癌效果。方法研究共计纳入82例中晚期宫颈癌患者,采取随机数字表法将患者分为两组,分别为放疗组及中成药组,每组41例,入组患者均接受常规化疗治疗,放疗组同时接受调强适形放疗治疗,中成药组在放疗组治疗基础上联合黄芪多糖注射液治疗,观察及对比两组数据情况:疗效与不良反应、治疗前后中医证候积分(下腹坠胀、乏力、气短、面色萎黄等)变化及鳞状上皮细胞癌抗原(squamous cell cancer,SCC)、糖类抗原125(carbohydrate antigen 125,CA125)及癌胚抗原(carcinoembryonic antigen,CEA)等肿瘤标志物水平变化、辅助性T细胞、细胞毒性T细胞、辅助性T细胞/细胞毒性T细胞等免疫功能指标变化、EORTC生存质量测定量表(European organization for research and treatment of cancer quality of life questionnaire,EORTC QLQ-C30)评分变化。结果中成药组近期治疗总有效率明显高于放疗组(P<0.05);中成药组白细胞下降率低于放疗组(P<0.05);两组其他不良反应率发生相当(P>0.05);两组治疗前中医证候积分(下腹坠胀、乏力、气短、面色萎黄等)、肿瘤标志物水平(CA125及CEA)、辅助性T细胞、细胞毒性T细胞、辅助性T细胞/细胞毒性T细胞、EORTC QLQ-C30评分等指标比较(P>0.05),治疗后两组中医证候积分(下腹坠胀、乏力、气短、面色萎黄等)及肿瘤标志物水平(SCC、CA125及CEA)均下降,EORTC QLQ-C30评分均提升,中成药组指标下降及提升程度明显高于放疗组(P<0.05);两组治疗后辅助性T细胞下降、细胞毒性T细胞上升,辅助性T细胞/细胞毒性T细胞下降,中成药组治疗后各项指标下降及上升程度均低于放疗组(P<0.05)。结论黄芪多糖注射液联合调强适形放疗治疗中晚期宫颈癌效果良好,可较好降低患者肿瘤标志物,改善患者病症,提升患者免疫功能与生活质量,治疗患者可耐受,较为安全可行。展开更多
目的观察培元养心法(背俞穴温针灸)治疗肾阳不足型膝关节退行性病变疗效。方法纳入肾阳不足型膝关节退行性病变患者80例,采取随机数字表法分为对照组40例与观察组40例,对照组接受膝关节置换术治疗,观察组在对照组治疗基础上结合培元养心...目的观察培元养心法(背俞穴温针灸)治疗肾阳不足型膝关节退行性病变疗效。方法纳入肾阳不足型膝关节退行性病变患者80例,采取随机数字表法分为对照组40例与观察组40例,对照组接受膝关节置换术治疗,观察组在对照组治疗基础上结合培元养心法(背俞穴温针灸)治疗,观察各组数据情况:疗效优良率、治疗前后中医证候积分变化、术后3 d及术后6 d、术后9 d患者的疼痛评分[视觉模拟疼痛评分法(Visual analogue scale,VAS)],治疗前后患者C反应蛋白(C-reactive protein,CRP)及肿瘤坏死因子α(Tumor necrosis factor-α,TNF-α)和白介素-6(Interleukin-6,IL-6)指标变化、治疗前后患者Lysholm膝关节量表评分变化、并发症发生率、治疗前、治疗2周及治疗4周身体健康评分(the MOS item short from health survey,SF-36)。结果观察组患者治疗效果优良率(95.00%,38/40)高于对照组(80.00%,32/40),差异有统计学意义(P<0.05);各组患者治疗后中医证候积分下降,炎症因子(CRP、TNF-α、IL-6)均显著下降,Lysholm膝关节量表总评分显著上升,观察组治疗后中医证候积分及炎症因子(CRP、TNF-α、IL-6)均低于对照组,Lysholm膝关节量表总评分高于对照组,差异有统计学意义(P<0.05);观察组患者术后3、6、9 d的VAS评分均比对照组更低,差异有统计学意义(P<0.05);对照组并发症率为20.00%(8/40),比观察组的5.00%(2/40)更低,差异有统计学意义(P<0.05);治疗2周及治疗4周后观察组患者的SF-36评分均高于对照组患者,差异有统计学意义(P<0.05)。结论培元养心法(背俞穴温针灸)治疗肾阳不足型膝关节退行性病变疗效良好,患者症状改善,膝关节功能改善,并发症少,治疗安全可靠,且患者治疗后身体健康好转,值得应用。展开更多
基金sponsored by the National Defense Science and Technology Key Laboratory Fund(Grant No.61422062205)the Equipment Pre-Research Fund(Grant No.JCKYS2022LD9)。
文摘Brain functional networks model the brain's ability to exchange information across different regions,aiding in the understanding of the cognitive process of human visual attention during target searching,thereby contributing to the advancement of camouflage evaluation.In this study,images with various camouflage effects were presented to observers to generate electroencephalography(EEG)signals,which were then used to construct a brain functional network.The topological parameters of the network were subsequently extracted and input into a machine learning model for training.The results indicate that most of the classifiers achieved accuracy rates exceeding 70%.Specifically,the Logistic algorithm achieved an accuracy of 81.67%.Therefore,it is possible to predict target camouflage effectiveness with high accuracy without the need to calculate discovery probability.The proposed method fully considers the aspects of human visual and cognitive processes,overcomes the subjectivity of human interpretation,and achieves stable and reliable accuracy.
文摘Objective The aim of this study was to determine the effect of successful coronary revascularisation on left ventricular diastolic function.Methods We consecutively studied the diastolic function by Doppler echocardiography in 125 patients with one vessel disease before and 48 hours after selective coronary angioplasty. The following parameters of left ventricular diastolic function were evaluated: peak early (VE, m/s) and peak late diastolic (VA, m/s) flow velocity, E/A ratio, acceleration time (AT, ms), deceleration time (DT, ms) and isovolumetric relaxation time (IVRT, ms). Ejection fraction (EF; %) was determined and used to characterise systolic left ventricular function. Results All of the patients were initially successful treated with coronary angioplasty (residual stenosis <40% ). In 98 patients( 78.4% ) stents were used to improve an inadequate result after coronary angioplasty. Both patient groups (27 patients with coronary angioplasty and 98 patients with combined coronary angioplasty and stent implantation) showed no relevant differences concerning sex, age, atherosclerotic risk factors, exercise capacity and results of exercise electrocardiography. All patients who underwent stent implantation showed an early improvement of left ventricular diastolic function 48 hours after revascularisation. Surprisingly there was no significant short term improvement (48 hours) of diastolic function in patients with initially successful angioplasty.Conclusions We suppose that stent implantation might normalize coronary blood flow faster than that of coronary balloon angioplasty.
文摘This paper provides a review of methods of assessing a fragmentation weapon’s effectiveness against a point target or an area target with keeping the focus on the necessity of using the Carleton damage function with the correct shape factor.First,cookie-cutter damage functions are redefined to preserve the shape factor of and to have the same lethal area as the corresponding Carleton damage function.Then,closed-form solutions of the effectiveness methods are obtained by using those cookie-cutter damage functions and the Carleton damage function.Finally,the closed-form solutions are applied to calculate the probability of damaging a point target and the expected fractional damage to an area target for several attack scenarios by using cookie-cutter damage functions and the Carleton damage functions with different shape factors.The comparison of the calculation results shows that using cookie-cutter damage functions or the Carleton damage function with a wrong shape factor results in quite significant differences from using the original Carleton damage function with a correct shape factor when weapon’s delivery error deviations are less than or comparable to the lengths of the lethal area and the aim point is far from a target.The effectiveness methods improved in this paper will be useful for mission planning utilizing the precision-guided munitions in circumstances where the collateral damage should be reduced.
文摘Germplasm effect reflects the quantitative relation between production ability of germplasm elements and yield （quality） of a certain crop, which can be shown by mathematic function, namely, germplasm effect function. Germplasm effect of a crop variety is an aggregation of many effective factors, and is restrained by different effective factors; constant increase of any one effect of germplasm elements would lead to law of effect decline, therefore, possible modes of transgenic crops effect function were deduced according to the law of effect decline. The possible modes of single transgenic germplasm effect function and multi-transgenic germplasm effect regression equation were discussed, and the characteristics of germplasm effect regression equation were analyzed in this paper.
基金Project(2022JJ30049)supported by the Natural Science Foundation of Hunan Province,China。
文摘The spin caloritronic properties of the Janus VSTe monolayer were investigated using density functional theory(DFT)and the non-equilibrium Green’s function(NEGF)method,implemented in the Atomistix Toolkit(ATK)package.Our study revealed significant spin-splitting within the Janus VSTe monolayer,which induced spin currents under a temperature gradient across the device.By applying a 1%tensile strain,the Janus VSTe monolayer exhibited a perfect thermal spin filtering effect(SFE),with the spin-up current nearly suppressed to zero.Both the unstrained and strained Janus VSTe monolayers demonstrated excellent spin caloritronic properties,with spin figures of merit of 10.915 and 8.432 at an average temperature of 100 K,respectively.Notably,these properties were found to be sensitive to temperature,performing optimally at lower temperatures.These results suggest a promising avenue for designing spin caloritronic devices aimed at efficient waste heat recovery.
文摘目的观察咳喘镇定汤在小儿咳嗽变异性哮喘治疗中的作用及对患儿嗜酸性粒细胞计数(eosinophil count,EOS)、白介素-23(interleukin-23,IL-23)/辅助性T细胞17(helper T cells17,Th17)轴的影响。方法选取2020年8月—2023年2月收治的小儿咳嗽变异性哮喘患儿104例,将患儿采用简单随机法分为两组。常规组给予止咳化痰、抗炎、平喘等常规治疗,咳喘镇定汤组在常规组基础上采用咳喘镇定汤辅助治疗。检测组间及组内T淋巴亚群、EOS、巨噬细胞炎症蛋白-1α(macrophage inflammatory protein-1α,MIP-1α)、Clara细胞分泌蛋白16(clara cell secreted protein 16,CC-16)、嗜酸细胞活化趋化因子(Eotaxin)、IL-23/Th17轴、小气道功能水平。评估组间及组内咳嗽症状评分、中医证候评分差异。统计组间疗效和不良反应。结果治疗前T淋巴亚群、CC-16、Eotaxin等差异无统计学意义(P>0.05)。两组治疗后CD_(8)^(+)、EOS、MIP-1α、Eotaxin降低,CC-16、CD_(4)^(+)、CD_(4)^(+)/CD_(8)^(+)升高,咳喘镇定汤组治疗后CD_(8)^(+)、EOS、MIP-1α、Eotaxin低于常规组,CC-16、CD_(4)^(+)、CD_(4)^(+)/CD_(8)^(+)高于常规组(P<0.05)。治疗前比较IL-23/Th17轴差异无统计学意义(P>0.05)。两组治疗后IL-23、Th17、白介素-17(interleukin-17,IL-17)降低,咳喘镇定汤组治疗后IL-23/Th17轴低于常规组(P<0.05)。治疗前相关评分无差异(P>0.05)。两组治疗后咳嗽症状评分、中医证候评分降低,咳喘镇定汤组治疗后咳嗽症状评分、中医症候评分低于常规组(P<0.05)。治疗前小气道功能无差异(P>0.05)。两组治疗后小气道功能升高,咳喘镇定汤组治疗后小气道功能高于常规组(P<0.05)。咳喘镇定汤组治愈13例,显效和有效共35例,总有效率92.31%高于常规组,差异有统计学意义(P<0.05)。结论咳喘镇定汤可通过调控小儿咳嗽变异性哮喘患儿IL-23/Th17轴,改善T淋巴亚群和小气道功能,减轻咳嗽症状,提高疗效。
文摘目的观察黄芪多糖注射液联合调强适形放疗治疗中晚期宫颈癌效果。方法研究共计纳入82例中晚期宫颈癌患者,采取随机数字表法将患者分为两组,分别为放疗组及中成药组,每组41例,入组患者均接受常规化疗治疗,放疗组同时接受调强适形放疗治疗,中成药组在放疗组治疗基础上联合黄芪多糖注射液治疗,观察及对比两组数据情况:疗效与不良反应、治疗前后中医证候积分(下腹坠胀、乏力、气短、面色萎黄等)变化及鳞状上皮细胞癌抗原(squamous cell cancer,SCC)、糖类抗原125(carbohydrate antigen 125,CA125)及癌胚抗原(carcinoembryonic antigen,CEA)等肿瘤标志物水平变化、辅助性T细胞、细胞毒性T细胞、辅助性T细胞/细胞毒性T细胞等免疫功能指标变化、EORTC生存质量测定量表(European organization for research and treatment of cancer quality of life questionnaire,EORTC QLQ-C30)评分变化。结果中成药组近期治疗总有效率明显高于放疗组(P<0.05);中成药组白细胞下降率低于放疗组(P<0.05);两组其他不良反应率发生相当(P>0.05);两组治疗前中医证候积分(下腹坠胀、乏力、气短、面色萎黄等)、肿瘤标志物水平(CA125及CEA)、辅助性T细胞、细胞毒性T细胞、辅助性T细胞/细胞毒性T细胞、EORTC QLQ-C30评分等指标比较(P>0.05),治疗后两组中医证候积分(下腹坠胀、乏力、气短、面色萎黄等)及肿瘤标志物水平(SCC、CA125及CEA)均下降,EORTC QLQ-C30评分均提升,中成药组指标下降及提升程度明显高于放疗组(P<0.05);两组治疗后辅助性T细胞下降、细胞毒性T细胞上升,辅助性T细胞/细胞毒性T细胞下降,中成药组治疗后各项指标下降及上升程度均低于放疗组(P<0.05)。结论黄芪多糖注射液联合调强适形放疗治疗中晚期宫颈癌效果良好,可较好降低患者肿瘤标志物,改善患者病症,提升患者免疫功能与生活质量,治疗患者可耐受,较为安全可行。
文摘目的观察培元养心法(背俞穴温针灸)治疗肾阳不足型膝关节退行性病变疗效。方法纳入肾阳不足型膝关节退行性病变患者80例,采取随机数字表法分为对照组40例与观察组40例,对照组接受膝关节置换术治疗,观察组在对照组治疗基础上结合培元养心法(背俞穴温针灸)治疗,观察各组数据情况:疗效优良率、治疗前后中医证候积分变化、术后3 d及术后6 d、术后9 d患者的疼痛评分[视觉模拟疼痛评分法(Visual analogue scale,VAS)],治疗前后患者C反应蛋白(C-reactive protein,CRP)及肿瘤坏死因子α(Tumor necrosis factor-α,TNF-α)和白介素-6(Interleukin-6,IL-6)指标变化、治疗前后患者Lysholm膝关节量表评分变化、并发症发生率、治疗前、治疗2周及治疗4周身体健康评分(the MOS item short from health survey,SF-36)。结果观察组患者治疗效果优良率(95.00%,38/40)高于对照组(80.00%,32/40),差异有统计学意义(P<0.05);各组患者治疗后中医证候积分下降,炎症因子(CRP、TNF-α、IL-6)均显著下降,Lysholm膝关节量表总评分显著上升,观察组治疗后中医证候积分及炎症因子(CRP、TNF-α、IL-6)均低于对照组,Lysholm膝关节量表总评分高于对照组,差异有统计学意义(P<0.05);观察组患者术后3、6、9 d的VAS评分均比对照组更低,差异有统计学意义(P<0.05);对照组并发症率为20.00%(8/40),比观察组的5.00%(2/40)更低,差异有统计学意义(P<0.05);治疗2周及治疗4周后观察组患者的SF-36评分均高于对照组患者,差异有统计学意义(P<0.05)。结论培元养心法(背俞穴温针灸)治疗肾阳不足型膝关节退行性病变疗效良好,患者症状改善,膝关节功能改善,并发症少,治疗安全可靠,且患者治疗后身体健康好转,值得应用。
