With the expansion of mountainous cities,many gully areas have been included in the scope of urban construction land.These gully areas will restrict urban construction because of sensitivity and instability caused by ...With the expansion of mountainous cities,many gully areas have been included in the scope of urban construction land.These gully areas will restrict urban construction because of sensitivity and instability caused by the unique ecological processes.This paper attempts to explore a planning and design strategy that combines ecological processes to reduce the risk of urban construction in gully areas.According to the ecological characteristics of gully areas,especially its suitability for urban construction,gully areas can be divided into three categories in the mountainous city:prevention and controlling gully—focusing on gully drainage;conservation gully—focusing on the construction of green space;utilization type gully—focusing on the development of gully towns.The utilization type gully can be used as urban construction land.For utilization type gullies,horizontal and vertical segmented planning strategies can adopt their respective ecological processes by land utilization,landscape construction,spatial layout and traffic organization matching the time-space natural process to form harmony human settlements.展开更多
Objective This study was to evaluate the efficacy and safety of a short acting reduced dose fibrinolytic regimen to promote early infarct related artery (IRA) patency for acyute myocardial infarction (AMI) patients re...Objective This study was to evaluate the efficacy and safety of a short acting reduced dose fibrinolytic regimen to promote early infarct related artery (IRA) patency for acyute myocardial infarction (AMI) patients referred for percutaneous coronary intervention (PCI).Methods Following aspirin and heparin, 166 patients were randomized to a 50 mg bolus of recombinant tissue type plasminogen activator(rt PA) or to a same volume sodium chloride injection followed by immediate primary PCI. The end points included patency rates on catheterization laboratory (cath lab) arrival, revascularization results when PCI was performed, complication rates, left ventricular function and restored patency rate following PCI. Results Patency on cath lab arrival was 64% with rt PA (34% TIMI 3,30% TIMI 2), while 31% of placebo (13% TIMI 3, 18% TIMI 2). There was no difference in the restored TIMI 3 rates of IRA between the two groups (85% vs 87%). No difference were observed in stroke or major bleeding. Left ventricular function was similar in both groups (52±9% vs 50±8%), but left ventricular ejection fraction fraction (LVEF) was higher with patent IRA (TIMI 3) on cath lab arrival than that of others (56±12% vs 48±10%).Conclusions Strategy thrombolytic regimens were compatible with subsequent PCI lead to more frequenc early recanalization (before cath lab arrival), which facilitates greater left ventricular function preservation with no augmentation of adverse events.展开更多
基金supported by National Key R&D Program of China“Optimization Technology for Urban New District Planning and Design(Grant No.2018YFC0704600)”
文摘With the expansion of mountainous cities,many gully areas have been included in the scope of urban construction land.These gully areas will restrict urban construction because of sensitivity and instability caused by the unique ecological processes.This paper attempts to explore a planning and design strategy that combines ecological processes to reduce the risk of urban construction in gully areas.According to the ecological characteristics of gully areas,especially its suitability for urban construction,gully areas can be divided into three categories in the mountainous city:prevention and controlling gully—focusing on gully drainage;conservation gully—focusing on the construction of green space;utilization type gully—focusing on the development of gully towns.The utilization type gully can be used as urban construction land.For utilization type gullies,horizontal and vertical segmented planning strategies can adopt their respective ecological processes by land utilization,landscape construction,spatial layout and traffic organization matching the time-space natural process to form harmony human settlements.
文摘Objective This study was to evaluate the efficacy and safety of a short acting reduced dose fibrinolytic regimen to promote early infarct related artery (IRA) patency for acyute myocardial infarction (AMI) patients referred for percutaneous coronary intervention (PCI).Methods Following aspirin and heparin, 166 patients were randomized to a 50 mg bolus of recombinant tissue type plasminogen activator(rt PA) or to a same volume sodium chloride injection followed by immediate primary PCI. The end points included patency rates on catheterization laboratory (cath lab) arrival, revascularization results when PCI was performed, complication rates, left ventricular function and restored patency rate following PCI. Results Patency on cath lab arrival was 64% with rt PA (34% TIMI 3,30% TIMI 2), while 31% of placebo (13% TIMI 3, 18% TIMI 2). There was no difference in the restored TIMI 3 rates of IRA between the two groups (85% vs 87%). No difference were observed in stroke or major bleeding. Left ventricular function was similar in both groups (52±9% vs 50±8%), but left ventricular ejection fraction fraction (LVEF) was higher with patent IRA (TIMI 3) on cath lab arrival than that of others (56±12% vs 48±10%).Conclusions Strategy thrombolytic regimens were compatible with subsequent PCI lead to more frequenc early recanalization (before cath lab arrival), which facilitates greater left ventricular function preservation with no augmentation of adverse events.