神经母细胞瘤（neuroblastoma,NB）是常见的儿童恶性肿瘤,在手术、放化疗及介入等多种手段综合治疗下,总体疗效仍然极差。近年来研究发现,果蝇zeste基因增强子同源物2（enhancer of zeste homolog 2,EZH2）能抑制相关抑癌基因,明显增加...神经母细胞瘤（neuroblastoma,NB）是常见的儿童恶性肿瘤,在手术、放化疗及介入等多种手段综合治疗下,总体疗效仍然极差。近年来研究发现,果蝇zeste基因增强子同源物2（enhancer of zeste homolog 2,EZH2）能抑制相关抑癌基因,明显增加神经母细胞瘤发生、发展的风险。GSK126是一种新型的选择性EZH2抑制剂,其在实体瘤方面的药效探究目前相对较少。展开更多
An adaptive ant colony algorithm is proposed based on dynamically adjusting the strategy of updating trail information. The algorithm can keep good balance between accelerating convergence and averting precocity and s...An adaptive ant colony algorithm is proposed based on dynamically adjusting the strategy of updating trail information. The algorithm can keep good balance between accelerating convergence and averting precocity and stagnation. The results of function optimization show that the algorithm has good searching ability and high convergence speed. The algorithm is employed to design a neuro-fuzzy controller for real-time control of an inverted pendulum. In order to avoid the combinatorial explosion of fuzzy rules due tσ multivariable inputs, a state variable synthesis scheme is employed to reduce the number of fuzzy rules greatly. The simulation results show that the designed controller can control the inverted pendulum successfully.展开更多
Currently computing information systems have entered a new stage and the security of systems is more and more serious, and the research on system security is developing in depth. This paper discusses neuro-computing a...Currently computing information systems have entered a new stage and the security of systems is more and more serious, and the research on system security is developing in depth. This paper discusses neuro-computing applications in security of network information systems.展开更多
An alpha-uniformized Markov chain is defined by the concept of equivalent infinitesimalgenerator for a semi-Markov decision process (SMDP) with both average- and discounted-criteria.According to the relations of their...An alpha-uniformized Markov chain is defined by the concept of equivalent infinitesimalgenerator for a semi-Markov decision process (SMDP) with both average- and discounted-criteria.According to the relations of their performance measures and performance potentials, the optimiza-tion of an SMDP can be realized by simulating the chain. For the critic model of neuro-dynamicprogramming (NDP), a neuro-policy iteration (NPI) algorithm is presented, and the performanceerror bound is shown as there are approximate error and improvement error in each iteration step.The obtained results may be extended to Markov systems, and have much applicability. Finally, anumerical example is provided.展开更多
文摘神经母细胞瘤（neuroblastoma,NB）是常见的儿童恶性肿瘤,在手术、放化疗及介入等多种手段综合治疗下,总体疗效仍然极差。近年来研究发现,果蝇zeste基因增强子同源物2（enhancer of zeste homolog 2,EZH2）能抑制相关抑癌基因,明显增加神经母细胞瘤发生、发展的风险。GSK126是一种新型的选择性EZH2抑制剂,其在实体瘤方面的药效探究目前相对较少。
文摘An adaptive ant colony algorithm is proposed based on dynamically adjusting the strategy of updating trail information. The algorithm can keep good balance between accelerating convergence and averting precocity and stagnation. The results of function optimization show that the algorithm has good searching ability and high convergence speed. The algorithm is employed to design a neuro-fuzzy controller for real-time control of an inverted pendulum. In order to avoid the combinatorial explosion of fuzzy rules due tσ multivariable inputs, a state variable synthesis scheme is employed to reduce the number of fuzzy rules greatly. The simulation results show that the designed controller can control the inverted pendulum successfully.
基金This project was supported by the Foundation of State Key Lab for Software Engineering at Wuhan University.
文摘Currently computing information systems have entered a new stage and the security of systems is more and more serious, and the research on system security is developing in depth. This paper discusses neuro-computing applications in security of network information systems.
文摘An alpha-uniformized Markov chain is defined by the concept of equivalent infinitesimalgenerator for a semi-Markov decision process (SMDP) with both average- and discounted-criteria.According to the relations of their performance measures and performance potentials, the optimiza-tion of an SMDP can be realized by simulating the chain. For the critic model of neuro-dynamicprogramming (NDP), a neuro-policy iteration (NPI) algorithm is presented, and the performanceerror bound is shown as there are approximate error and improvement error in each iteration step.The obtained results may be extended to Markov systems, and have much applicability. Finally, anumerical example is provided.
