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Projective synchronization control and simulation of drive system and response network
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作者 LI De-kui 《兰州大学学报(自然科学版)》 北大核心 2025年第2期208-214,共7页
Projective synchronization problems of a drive system and a particular response network were investigated,where the drive system is an arbitrary system with n+1 dimensions;it may be a linear or nonlinear system,and ev... Projective synchronization problems of a drive system and a particular response network were investigated,where the drive system is an arbitrary system with n+1 dimensions;it may be a linear or nonlinear system,and even a chaotic or hyperchaotic system,the response network is complex system coupled by N nodes,and every node is showed by the approximately linear part of the drive system.Only controlling any one node of the response network by designed controller can achieve the projective synchronization.Some numerical examples were employed to verify the effectiveness and correctness of the designed controller. 展开更多
关键词 pinning control projective synchronization drive system response network
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双向再调制PON网络的数据擦除性能分析
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作者 李红安 吴静松 《中国工程机械学报》 北大核心 2025年第1期100-103,109,共5页
数据擦除机制是未来宽带接入网络的最经济、最具前途的方案。本文建立基于注入法布里-珀罗(FP-LD)激光器数据擦除式的载波再调制无色双向波分复用无源光网络(WDM-PON)模型,在10 Gbit/s速率下比较FP激光器的偏置电流、消光比、限制因子... 数据擦除机制是未来宽带接入网络的最经济、最具前途的方案。本文建立基于注入法布里-珀罗(FP-LD)激光器数据擦除式的载波再调制无色双向波分复用无源光网络(WDM-PON)模型,在10 Gbit/s速率下比较FP激光器的偏置电流、消光比、限制因子和注入功率等参数对数据擦除效率的影响。仿真采用Optisystem 15.0软件,设定注入功率为-25~-5 dBm,偏置电流为20~100 mA。结果显示,该模型具有较好的擦除性能,并且能够抑制下行残留消光比小于0.5 dB。 展开更多
关键词 双向再调制 无源光网络(pon) 数据擦除 无色 传输性能
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改进Deep Q Networks的交通信号均衡调度算法
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作者 贺道坤 《机械设计与制造》 北大核心 2025年第4期135-140,共6页
为进一步缓解城市道路高峰时段十字路口的交通拥堵现象,实现路口各道路车流均衡通过,基于改进Deep Q Networks提出了一种的交通信号均衡调度算法。提取十字路口与交通信号调度最相关的特征,分别建立单向十字路口交通信号模型和线性双向... 为进一步缓解城市道路高峰时段十字路口的交通拥堵现象,实现路口各道路车流均衡通过,基于改进Deep Q Networks提出了一种的交通信号均衡调度算法。提取十字路口与交通信号调度最相关的特征,分别建立单向十字路口交通信号模型和线性双向十字路口交通信号模型,并基于此构建交通信号调度优化模型;针对Deep Q Networks算法在交通信号调度问题应用中所存在的收敛性、过估计等不足,对Deep Q Networks进行竞争网络改进、双网络改进以及梯度更新策略改进,提出相适应的均衡调度算法。通过与经典Deep Q Networks仿真比对,验证论文算法对交通信号调度问题的适用性和优越性。基于城市道路数据,分别针对两种场景进行仿真计算,仿真结果表明该算法能够有效缩减十字路口车辆排队长度,均衡各路口车流通行量,缓解高峰出行方向的道路拥堵现象,有利于十字路口交通信号调度效益的提升。 展开更多
关键词 交通信号调度 十字路口 Deep Q networks 深度强化学习 智能交通
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Multi-agent cooperative intrusion response in mobile adhoc networks 被引量:6
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作者 Yi Ping Zou Futai +1 位作者 Jiang Xinghao Li Jianhua 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2007年第4期785-794,共10页
The nature of adhoc networks makes them vulnerable to security attacks. Many security technologies such as intrusion prevention and intrusion detection are passive in response to intrusions in that their countermea- s... The nature of adhoc networks makes them vulnerable to security attacks. Many security technologies such as intrusion prevention and intrusion detection are passive in response to intrusions in that their countermea- sures are only to protect the networks, and there is no automated network-wide counteraction against detected intrusions, the architecture of cooperation intrusion response based multi-agent is propose. The architecture is composed of mobile agents. Monitor agent resides on every node and monitors its neighbor nodes. Decision agent collects information from monitor nodes and detects an intrusion by security policies. When an intruder is found in the architecture, the block agents will get to the neighbor nodes of the intruder and form the mobile firewall to isolate the intruder. In the end, we evaluate it by simulation. 展开更多
关键词 computer networks SECURITY mobile agent mobile adhoc networks intrusion detection intrusion response
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Component Content Soft-sensor Based on Neural Networks in Rare-earth Countercurrent Extraction Process 被引量:13
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作者 YANG Hui CHAI Tian-You 《自动化学报》 EI CSCD 北大核心 2006年第4期489-495,共7页
Throught fusion of the mechanism modeling and the neural networks modeling,a compo- nent content soft-sensor,which is composed of the equilibrium calculation model for multi-component rare earth extraction and the err... Throught fusion of the mechanism modeling and the neural networks modeling,a compo- nent content soft-sensor,which is composed of the equilibrium calculation model for multi-component rare earth extraction and the error compensation model of fuzzy system,is proposed to solve the prob- lem that the component content in countercurrent rare-earth extraction process is hardly measured on-line.An industry experiment in the extraction Y process by HAB using this hybrid soft-sensor proves its effectiveness. 展开更多
关键词 RARE-EARTH countercurrent extraction soft-sensor equilibrium calculation model neural networks
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Failure Impact,Availability and Cost Analysis of PONs Based on a Network Geometric Model 被引量:1
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作者 FERNANDEZ Alvaro STOL Norvald 《光子学报》 EI CAS CSCD 北大核心 2014年第S1期18-24,共7页
Passive Optical Networks(PONs)are considered as the preferred solution for broadband fibre-based access networks.This is because PONs present low cost deployment,low energy consumption and also meet high bandwidth dem... Passive Optical Networks(PONs)are considered as the preferred solution for broadband fibre-based access networks.This is because PONs present low cost deployment,low energy consumption and also meet high bandwidth demands from end users.In addition,end users expect a high availability for access networks,while operators are more concerned about reducing the failure impact(number of clients affected by failures).Moreover,operators are also interested in reducing the cost of the access network.This paper provides a deep insight into the consequences that the physical topology and design decisions cause on the availability,the failure impact and the cost of a PON.In order to do that,the physical layout of the PON deployment area is approximated by a network geometric model.A PON deployed according to the geometric model is then assessed in terms of failure impact,availability and cost.This way,the effects of different design decisions and the physical layout on these three parameters are evaluated.In addition,the tradeoffs between availability,failure impact and cost caused by planning decisions and the physical topology are identified and pinpointed. 展开更多
关键词 AVAILABILITY FAILURE IMPACT CAPITAL Expenditures Passive Optical networks network geometric model
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Exponential stability for cellular neural networks: an LMI approach 被引量:1
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作者 Liu Deyou Zhang Jianhua Guan Xinping 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2007年第1期68-71,共4页
A new sufficient conditions for the global exponential stability of the equilibrium point for delayed cellular neural networks (DCNNs) is presented. It is shown that the use of a more general type of Lyapunov-Krasov... A new sufficient conditions for the global exponential stability of the equilibrium point for delayed cellular neural networks (DCNNs) is presented. It is shown that the use of a more general type of Lyapunov-Krasovskii function enables the derivation of new results for an exponential stability of the equilibrium point for DCNNs. The results establish a relation between the delay time and the parameters of the network. The results are also compared with one of the most recent results derived in the literature. 展开更多
关键词 Delayed cellular neural networks LMI Neural networks Exponential stability
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Electricity price forecasting using generalized regression neural network based on principal components analysis 被引量:1
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作者 牛东晓 刘达 邢棉 《Journal of Central South University》 SCIE EI CAS 2008年第S2期316-320,共5页
A combined model based on principal components analysis (PCA) and generalized regression neural network (GRNN) was adopted to forecast electricity price in day-ahead electricity market. PCA was applied to mine the mai... A combined model based on principal components analysis (PCA) and generalized regression neural network (GRNN) was adopted to forecast electricity price in day-ahead electricity market. PCA was applied to mine the main influence on day-ahead price, avoiding the strong correlation between the input factors that might influence electricity price, such as the load of the forecasting hour, other history loads and prices, weather and temperature; then GRNN was employed to forecast electricity price according to the main information extracted by PCA. To prove the efficiency of the combined model, a case from PJM (Pennsylvania-New Jersey-Maryland) day-ahead electricity market was evaluated. Compared to back-propagation (BP) neural network and standard GRNN, the combined method reduces the mean absolute percentage error about 3%. 展开更多
关键词 ELECTRICITY PRICE forecasting GENERALIZED regression NEURAL network principal COMponENTS analysis
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用于PON的低成本CMOS BM-TIA设计 被引量:1
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作者 赵婉青 夏翼飞 +5 位作者 李佳 徐颂秦 马帅哲 杨睿煊 耿莉 李丹 《光通信研究》 北大核心 2025年第1期52-58,共7页
【目的】在高速率无源光网络(PON)需求的快速增长下,低成本低噪声突发模式跨阻放大器(BM-TIA)成为其关键的制约因素。文章基于低成本40 nm互补金属氧化物半导体(CMOS)工艺,设计了一种适用于10吉比特对称无源光网络(XGS-PON)的快速建立... 【目的】在高速率无源光网络(PON)需求的快速增长下,低成本低噪声突发模式跨阻放大器(BM-TIA)成为其关键的制约因素。文章基于低成本40 nm互补金属氧化物半导体(CMOS)工艺,设计了一种适用于10吉比特对称无源光网络(XGS-PON)的快速建立低噪声BM-TIA,其可兼容12.5、10.0和2.5 Gbit/s 3种信号速率。【方法】为突破CMOS工艺的带宽和噪声瓶颈,TIA通过多级放大、输入电感均衡网络及提高电源电压的方法实现了要求的低噪声。采用前向放大器与反馈电阻共同调节的增益调节方式,实现了3档位的增益变化和速率变化。针对突发模式信号采用快速直流(DC)消除环路(AOC)来精准消除雪崩击穿二极管(APD)输入的DC电流,运用电荷分享技术加速失调消除环路的建立,并通过转换AOC环路时间常数的方法来抑制基线漂移。【结果】芯片采用40 nm CMOS工艺设计制造,裸片尺寸为945μm×945μm。芯片搭配商用10 Gbit/s APD进行同轴罐(TO-CAN)封装测试。测试结果表明,在12.5、10.0以及2.5 Gbit/s速率下,芯片的灵敏度分别为-29.7,-33.0和-37.6 dBm。在不同速率下,饱和输入光电流均可达2.5 mA,实现了24.7、28.2和32.8 dB的大输入动态范围。芯片的静态功耗为82.5 mW,在整个输入光功率范围内,突发模式下AOC的建立时间均小于23 ns。【结论】将文章所提芯片应用于XGS-PON,不但为基于CMOS工艺的低成本低噪声BM-TIA设计提供了借鉴,也对更高速率PON场景下的芯片设计具有指导意义。 展开更多
关键词 互补金属氧化物半导体工艺 10吉比特对称无源光网络 突发模式跨阻放大器 多速率兼容 快速建立
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Optimization of processing parameters for microwave drying of selenium-rich slag using incremental improved back-propagation neural network and response surface methodology 被引量:4
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作者 李英伟 彭金辉 +2 位作者 梁贵安 李玮 张世敏 《Journal of Central South University》 SCIE EI CAS 2011年第5期1441-1447,共7页
In the non-linear microwave drying process, the incremental improved back-propagation (BP) neural network and response surface methodology (RSM) were used to build a predictive model of the combined effects of ind... In the non-linear microwave drying process, the incremental improved back-propagation (BP) neural network and response surface methodology (RSM) were used to build a predictive model of the combined effects of independent variables (the microwave power, the acting time and the rotational frequency) for microwave drying of selenium-rich slag. The optimum operating conditions obtained from the quadratic form of the RSM are: the microwave power of 14.97 kW, the acting time of 89.58 min, the rotational frequency of 10.94 Hz, and the temperature of 136.407 ℃. The relative dehydration rate of 97.1895% is obtained. Under the optimum operating conditions, the incremental improved BP neural network prediction model can predict the drying process results and different effects on the results of the independent variables. The verification experiments demonstrate the prediction accuracy of the network, and the mean squared error is 0.16. The optimized results indicate that RSM can optimize the experimental conditions within much more broad range by considering the combination of factors and the neural network model can predict the results effectively and provide the theoretical guidance for the follow-up production process. 展开更多
关键词 microwave drying response surface methodology optimization incremental improved back-propagation neural network PREDICTION
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Global exponential stability for delayed cellular neural networks and estimate of exponential convergence rate 被引量:1
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作者 张强 马润年 许进 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2004年第3期344-349,共6页
Some sufficient conditions for the global exponential stability and lower bounds on the rate of exponential convergence of the cellular neural networks with delay (DCNNs) are obtained by means of a method based on del... Some sufficient conditions for the global exponential stability and lower bounds on the rate of exponential convergence of the cellular neural networks with delay (DCNNs) are obtained by means of a method based on delay differential inequality. The method, which does not make use of any Lyapunov functional, is simple and valid for the stability analysis of neural networks with delay. Some previously established results in this paper are shown to be special casses of the presented result. 展开更多
关键词 global exponential stability convergence rate cellular neural networks with delay delay differential inequality.
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Ballistic response of armour plates using Generative Adversarial Networks 被引量:2
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作者 S.Thompson F.Teixeira-Dias +1 位作者 M.Paulino A.Hamilton 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2022年第9期1513-1522,共10页
It is important to understand how ballistic materials respond to impact from projectiles such that informed decisions can be made in the design process of protective armour systems. Ballistic testing is a standards-ba... It is important to understand how ballistic materials respond to impact from projectiles such that informed decisions can be made in the design process of protective armour systems. Ballistic testing is a standards-based process where materials are tested to determine whether they meet protection, safety and performance criteria. For the V50ballistic test, projectiles are fired at different velocities to determine a key design parameter known as the ballistic limit velocity(BLV), the velocity above which projectiles perforate the target. These tests, however, are destructive by nature and as such there can be considerable associated costs, especially when studying complex armour materials and systems. This study proposes a unique solution to the problem using a recent class of machine learning system known as the Generative Adversarial Network(GAN). The GAN can be used to generate new ballistic samples as opposed to performing additional destructive experiments. A GAN network architecture is tested and trained on three different ballistic data sets, and their performance is compared. The trained networks were able to successfully produce ballistic curves with an overall RMSE of between 10 and 20 % and predicted the V50BLV in each case with an error of less than 5 %. The results demonstrate that it is possible to train generative networks on a limited number of ballistic samples and use the trained network to generate many new samples representative of the data that it was trained on. The paper spotlights the benefits that generative networks can bring to ballistic applications and provides an alternative to expensive testing during the early stages of the design process. 展开更多
关键词 Machine learning Generative Adversarial networks GAN Terminal ballistics Armour systems
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车载光通信趋势分析及发展车载无源光网络(V-PON)的建议
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作者 陈山枝 罗文勇 《电信科学》 北大核心 2025年第7期1-14,共14页
首先,分析了汽车智能化、网联化趋势,以及汽车电子电气架构(electrical electronic architecture,EEA)演进给车内通信带来的新需求与新挑战,指出车载光通信也会经历类似电信运营商固定接入网的“光进铜退”的发展历程,实现从“窄带通信... 首先,分析了汽车智能化、网联化趋势,以及汽车电子电气架构(electrical electronic architecture,EEA)演进给车内通信带来的新需求与新挑战,指出车载光通信也会经历类似电信运营商固定接入网的“光进铜退”的发展历程,实现从“窄带通信+铜缆线束”向“宽带通信+光纤线束”的变革。其次,提出车载无源光网络(vehicular passive optical network,V-PON)的技术路线与标准建议:针对车内通信需求及特殊工作环境带来的挑战,在已有PON技术的基础上进行适应性改进,攻克相关核心技术,形成V-PON标准规范。该方案可充分发挥中国在光通信及PON领域的技术优势和规模产业优势,助力中国在车载通信领域形成核心知识产权,为智能网联汽车转型升级提供支撑,进而提升中国相关产业的国际竞争力。 展开更多
关键词 智能网联汽车 车内网 EEA V-pon 铜缆线束 光纤线束
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Component based ant routing protocols analysis over mobile ad hoc networks 被引量:1
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作者 曲大鹏 王兴伟 黄敏 《Journal of Central South University》 SCIE EI CAS 2013年第9期2378-2387,共10页
To deeply exploit the mechanisms of ant colony optimization (ACO) applied to develop routing in mobile ad hoe networks (MANETS),some existing representative ant colony routing protocols were analyzed and compared.... To deeply exploit the mechanisms of ant colony optimization (ACO) applied to develop routing in mobile ad hoe networks (MANETS),some existing representative ant colony routing protocols were analyzed and compared.The analysis results show that every routing protocol has its own characteristics and competitive environment.No routing protocol is better than others in all aspects.Therefore,based on no free lunch theory,ant routing protocols were decomposed into three key components:route discovery,route maintenance (including route refreshing and route failure handling) and data forwarding.Moreover,component based ant routing protocol (CBAR) was proposed.For purpose of analysis,it only maintained basic ant routing process,and it was simple and efficient with a low overhead.Subsequently,different mechanisms used in every component and their effect on performance were analyzed and tested by simulations.Finally,future research strategies and trends were also summarized. 展开更多
关键词 routing protocol mobile ad hoc networks ant colony optimization route discovery route maintenance data forwarding
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Independent component analysis to physical-layer network coding over wireless fading channels
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作者 Bing Du Xiaoming Tao 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2013年第2期196-203,共8页
A new combinational technology is proposed,which is feasible to apply physical-layer network coding(PNC) to wireless fading channels by employing the harmful interference strategically.The key step of PNC is that so... A new combinational technology is proposed,which is feasible to apply physical-layer network coding(PNC) to wireless fading channels by employing the harmful interference strategically.The key step of PNC is that sources broadcast signals simultaneously without orthogonal scheduling.Naturally,the signals overlap in the free space at the receivers.Since the signals from different sources are mutual independent,rooted on this rational assumption,an enhanced joint diagonalization separation named altering row diagonalization(ARD) algorithm is exploited to separate these signals by maximizing the cost function measuring independence among them.This ARD PNC(APNC) methodology provides an innovative way to implement signal-level network coding at the presence of interference and without any priori information about channels in fading environments.In conclusions,the proposed APNC performs well with higher bandwidth utility and lower error rate. 展开更多
关键词 physical-layer network coding (PNC) independentcomponent analysis (ICA) joint diagonalization network coding cooperative communications.
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Research on Application Technology Oriented Rapid Response Manufacturing in the Distributed Network Environment
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作者 JIN Ji-wen, NI Yan-rong, XI Jun-tong, FAN Fei-ya, JIN Ye (CIM Institute, Department of Mechanical Engineering, Shanghai Jiaotong University, Shanghai 200030, China) 《厦门大学学报(自然科学版)》 CAS CSCD 北大核心 2002年第S1期43-44,共2页
A new chance of developing traditional manufacturing industry comes forth with the development of network technology. Application technology oriented rapid response manufacturing in the distributed network environment... A new chance of developing traditional manufacturing industry comes forth with the development of network technology. Application technology oriented rapid response manufacturing in the distributed network environments, that is, how to take advantage of the Intranet and Internet, combine the numerous manufacturing resources spread around the region, the country and even the globe is the key to the agile design, manufacturing and the buildup of comprehensively competitive power, at the same time, is also an important research direction in the field of advanced manufacturing technology. Rapid response manufacturing in the distributed network environment is a newly manufactory pattern that can be used to implement the conception of agile design and manufacturing, but there are some new problems coming with it, which will directly influence the enterprise’s ability of rapid response in the distributed network manufacturing pattern and lead to the failure of the league and the lost of the given orders. In this paper, we establish some approaches to solve these problems in product development process. The paper then presents the research on key application technologies and solutions includes: network safety strategy which guarantees data transferring among the leaguer members, production data management based on Web/DOT (Distributed Object Technology) and XML criteria which guarantees data exchange in structure-variance characteristic environments, the network platform which provides the conversion service of different types of CAD files each other. All of these solutions are aim for technology problems existing in the distributed network environments and among the league members. Finally, the paper takes one project, that is, the establishment of the online application service system for Shanghai Advance Manufacturing Technology Research Center as a good instance. 展开更多
关键词 distributed network environment rapid response manufacturing data exchange
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Semantic network based component organization model for program mining
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作者 王斌 张尧学 陈松乔 《Journal of Central South University of Technology》 2003年第4期369-374,共6页
Based on the definition of component ontology, an effective component classification mechanism and a facet named component relationship are proposed. Then an application domain oriented, hierarchical component organiz... Based on the definition of component ontology, an effective component classification mechanism and a facet named component relationship are proposed. Then an application domain oriented, hierarchical component organization model is established. At last a hierarchical component semantic network (HCSN) described by ontology interchange language(OIL) is presented and then its function is described. Using HCSN and cooperating with other components retrieving algorithms based on component description, other components information and their assembly or composite modes related to the key component can be found. Based on HCSN, component directory library is catalogued and a prototype system is constructed. The prototype system proves that component library organization based on this model gives guarantee to the reliability of component assembly during program mining. 展开更多
关键词 COMponENT SEMANTIC network AGENT PROGRAM MINING ONTOLOGY
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基于50 Gbit/s Combo PON OLT光组件的研究 被引量:1
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作者 成璇璇 石川 +3 位作者 马洪勇 梅晓鹤 丁深 秦强 《光通信研究》 北大核心 2025年第2期80-85,共6页
【目的】随着视频业务逐渐成为宽带网络的核心支柱,无源光网络(PON)技术迅速发展,从传统的家庭宽带接入领域迈向政企、工业智能制造和远程医疗等更为广泛的应用领域,由此对网络的带宽、时延、丢包率和抖动等业务质量要求日益苛刻。在这... 【目的】随着视频业务逐渐成为宽带网络的核心支柱,无源光网络(PON)技术迅速发展,从传统的家庭宽带接入领域迈向政企、工业智能制造和远程医疗等更为广泛的应用领域,由此对网络的带宽、时延、丢包率和抖动等业务质量要求日益苛刻。在这样的背景下,50 Gbit/s的下一代光接入网技术应运而生,50 Gbit/s PON不仅要提供超过10 Gbit/s PON 4倍以上的接入带宽,还需强化业务支撑能力、网络安全防护以及确保与现有10 Gbit/s PON技术的兼容性和平滑演进。在实现的过程中,光发射组件的研发尤为关键。【方法】文章重点介绍了一种基于混合集成封装技术的50 Gbit/s Combo PON光线路终端(LOT)光组件。这款光组件通过折叠的光路设计,解决了发射端和接收端多通道波长合分波的技术难题,显著降低了收发器件在同一管壳内的串扰问题。【结果】通过精心设计的4通道小型可插拔接口(QSFP)28封装尺寸模块,实现了在金属气密性管壳内的3发3收功能。同时,得益于先进的优化设计,发射端对接收端的串扰明显降低,效果提升达到20~30 dB。这一重要突破不仅提高了光组件的性能,也为50 Gbit/s PON的商用部署奠定了坚实基础。【结论】测试结果表明,文章所提光组件的波长性能完全符合国际电信联盟-电信标准化部门(ITU-T)G.9804.3国际标准的要求,其工作眼图和灵敏度均达到了预期指标。这意味着50 Gbit/s Combo PON OLT光组件已经具备了在实际网络环境中应用的能力。展望未来,随着技术的不断进步和应用需求的持续增长,50 Gbit/s PON将在推动宽带网络升级、增强业务支撑和提升用户体验等方面发挥重要作用。期待这一领域继续涌现更多创新成果,共同推动光网络技术的繁荣发展。 展开更多
关键词 50 Gbit/s Combo无源光网络 光线路终端 光发射组件
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Integration of single-cell RNA sequencing and network disturbance to elucidate crosstalk between multi-components drug and trigeminal ganglia cells in migraine
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作者 ZHANG Bo XI Yujie +3 位作者 HUANG Ying ZHANG Yi GUO Feifei YANG Hongjun 《中国药理学与毒理学杂志》 CAS 北大核心 2023年第S01期38-39,共2页
OBJECTIVE To clarify the mecha⁃nism of Tou Tong Ning capsule(TTNC)and elu⁃cidate crosstalk between multi-components drug and trigeminal ganglia cells in migraine.METH⁃ODS We integrated single-cell RNA sequencing data ... OBJECTIVE To clarify the mecha⁃nism of Tou Tong Ning capsule(TTNC)and elu⁃cidate crosstalk between multi-components drug and trigeminal ganglia cells in migraine.METH⁃ODS We integrated single-cell RNA sequencing data and a quantitative evaluation algorithm of the disturbance of multi-target drugs on the dis⁃ease network to explore the specific pathology of TTNC for migraine.Cerebrovascular smooth muscle spasmolytic activity experiment was car⁃ried out to verify the results of bioinformatics analysis.RESULTS TTNC can effectively regu⁃late the functions of synaptic signaling,inflamma⁃tion and immune response,and cerebrovascular smooth muscle.For different cell subtypes of tri⁃geminal ganglia,TTNC can significantly disturb the robustness on neuronal cell networks and non-neural networks(fibroblast and vascular cells),indicating TTNC vasodilation activity of brain vessels and neural regulation activities of various neuro types.Contraction of cerebrovas⁃cular smooth muscle of mouse ex vivo confirmed the vasodilation activity of TTNC and active com⁃pounds(Emodin,Luteolin and Levistilide A).And literature mining confirmed the vasospasmolytic activity and neuroprotective effect activity of TTNC.CONCLUSIONS Integrating single-cell data and network disturbance tools provides a new strategy for the MoA of multi-components drug through cell subtyping. 展开更多
关键词 Tou Tong Ning capsule(TTNC) MIGRAINE ScRNA-sq network disturbance vascular cell
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Four optimal design approaches of high-order finite-impulse response filters based on neural network
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作者 王小华 何怡刚 刘美容 《Journal of Central South University of Technology》 EI 2007年第1期94-99,共6页
Four optimal approaches of high-order finite-impulse response(FIR) digital filters were developed for designing four types filters using neural network algorithms. The solutions were presented as parallel algorithms t... Four optimal approaches of high-order finite-impulse response(FIR) digital filters were developed for designing four types filters using neural network algorithms. The solutions were presented as parallel algorithms to approximate the desired frequency response specification. Therefore, these methods avoid matrix inversion, and make a fast calculation of the filter’s coefficients possible. The convergence theorems of these proposed algorithms were presented and proved to illustrate them stable, and the implementation of these methods was described together with some design guidelines. The simulation results show that the ripples of the designed FIR filters are significantly little in the pass-band and stop-band, and the proposed algorithms are of fast convergence. 展开更多
关键词 high-order finite-impulse response digital filter frequency response neural network convergence theorem
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