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Comprehensive multivariate grey incidence degree based on principal component analysis 被引量:6
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作者 Ke Zhang Yintao Zhang Pinpin Qu 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2014年第5期840-847,共8页
To overcome the too fine-grained granularity problem of multivariate grey incidence analysis and to explore the comprehensive incidence analysis model, three multivariate grey incidences degree models based on princip... To overcome the too fine-grained granularity problem of multivariate grey incidence analysis and to explore the comprehensive incidence analysis model, three multivariate grey incidences degree models based on principal component analysis (PCA) are proposed. Firstly, the PCA method is introduced to extract the feature sequences of a behavioral matrix. Then, the grey incidence analysis between two behavioral matrices is transformed into the similarity and nearness measure between their feature sequences. Based on the classic grey incidence analysis theory, absolute and relative incidence degree models for feature sequences are constructed, and a comprehensive grey incidence model is proposed. Furthermore, the properties of models are researched. It proves that the proposed models satisfy the properties of translation invariance, multiple transformation invariance, and axioms of the grey incidence analysis, respectively. Finally, a case is studied. The results illustrate that the model is effective than other multivariate grey incidence analysis models. 展开更多
关键词 grey system multivariate grey incidence analysis behavioral matrix principal component analysis (PCA).
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Application of multivariate statistical techniques in assessment of surface water quality in Second Songhua River basin,China 被引量:4
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作者 郑力燕 于宏兵 王启山 《Journal of Central South University》 SCIE EI CAS CSCD 2016年第5期1040-1051,共12页
Multivariate statistical techniques,such as cluster analysis(CA),discriminant analysis(DA),principal component analysis(PCA) and factor analysis(FA),were applied to evaluate and interpret the surface water quality dat... Multivariate statistical techniques,such as cluster analysis(CA),discriminant analysis(DA),principal component analysis(PCA) and factor analysis(FA),were applied to evaluate and interpret the surface water quality data sets of the Second Songhua River(SSHR) basin in China,obtained during two years(2012-2013) of monitoring of 10 physicochemical parameters at 15 different sites.The results showed that most of physicochemical parameters varied significantly among the sampling sites.Three significant groups,highly polluted(HP),moderately polluted(MP) and less polluted(LP),of sampling sites were obtained through Hierarchical agglomerative CA on the basis of similarity of water quality characteristics.DA identified p H,F,DO,NH3-N,COD and VPhs were the most important parameters contributing to spatial variations of surface water quality.However,DA did not give a considerable data reduction(40% reduction).PCA/FA resulted in three,three and four latent factors explaining 70%,62% and 71% of the total variance in water quality data sets of HP,MP and LP regions,respectively.FA revealed that the SSHR water chemistry was strongly affected by anthropogenic activities(point sources:industrial effluents and wastewater treatment plants;non-point sources:domestic sewage,livestock operations and agricultural activities) and natural processes(seasonal effect,and natural inputs).PCA/FA in the whole basin showed the best results for data reduction because it used only two parameters(about 80% reduction) as the most important parameters to explain 72% of the data variation.Thus,this work illustrated the utility of multivariate statistical techniques for analysis and interpretation of datasets and,in water quality assessment,identification of pollution sources/factors and understanding spatial variations in water quality for effective stream water quality management. 展开更多
关键词 Second Songhua River basin water quality multivariate statistical techniques cluster analysis discriminant analysis principal component analysis factor analysis
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Fault detection of excavator’s hydraulic system based on dynamic principal component analysis 被引量:5
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作者 何清华 贺湘宇 朱建新 《Journal of Central South University of Technology》 2008年第5期700-705,共6页
In order to improve reliability of the excavator's hydraulic system, a fault detection approach based on dynamic principal component analysis(PCA) was proposed. Dynamic PCA is an extension of PCA, which can effect... In order to improve reliability of the excavator's hydraulic system, a fault detection approach based on dynamic principal component analysis(PCA) was proposed. Dynamic PCA is an extension of PCA, which can effectively extract the dynamic relations among process variables. With this approach, normal samples were used as training data to develop a dynamic PCA model in the first step. Secondly, the dynamic PCA model decomposed the testing data into projections to the principal component subspace(PCS) and residual subspace(RS). Thirdly, T2 statistic and Q statistic performed as indexes of fault detection in PCS and RS, respectively. Several simulated faults were introduced to validate the approach. The results show that the dynamic PCA model developed is able to detect overall faults by using T2 statistic and Q statistic. By simulation analysis, the proposed approach achieves an accuracy of 95% for 20 test sample sets, which shows that the fault detection approach can be effectively applied to the excavator's hydraulic system. 展开更多
关键词 hydraulic system EXCAVATOR fault detection principal component analysis multivariate statistics
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Property analysis of bistatic forward-looking SAR with arbitrary geometry 被引量:2
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作者 Ziqiang Meng Yachao Li +1 位作者 Mengdao Xing Zheng Bao 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2016年第1期111-127,共17页
Bistatic forward-looking synthetic aperture radar(SAR) has many advantages and applications owing to its twodimensional imaging capability.There could be various imaging configurations because of the geometric flexi... Bistatic forward-looking synthetic aperture radar(SAR) has many advantages and applications owing to its twodimensional imaging capability.There could be various imaging configurations because of the geometric flexibility of bistatic platforms,resulting in kinds of models built independently among which there could be some similar even the same motion features.Comprehensive research on such systems in a more comprehensive and general point of view is required to address their difference and consistency.Property analysis of bistatic forwardlooking SAR with arbitrary geometry is achieved including stripmap and spotlight modes on airborne platform,missile-borne platform,and hybrid platform of both.Emphasis is placed on azimuth space variance of some key parameters significantly affecting the subsequent imaging processing,based on which the frequency spectra are further described and compared considering respective features of different platforms for frequency imaging algorithm developing.Simulation results confirm the effectiveness and correctness of our analysis. 展开更多
关键词 bistatic forward-looking synthetic aperture radar(SAR) comprehensive research property analysis azimuth space variance.
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基于GC×GC-QTOF-MS分析不同品种汝城白毛茶白茶的香气特征 被引量:3
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作者 安勤 鲍肃都 +6 位作者 陈宏宇 安会敏 陈圆 张欣仪 刘洋 刘仲华 黄建安 《食品科学》 北大核心 2025年第4期163-171,共9页
采摘汝城白毛茶1号(RT1)、汝城白毛茶2号(RT2)和汝城白毛茶群体种(QT3)3个品系(种)的一芽二叶鲜叶按照相同的加工工艺(萎凋、干燥)加工成白茶,并探究其香气品质特征。感官定量描述法、顶空固相微萃取法和全二维气相色谱-四极杆-飞行时... 采摘汝城白毛茶1号(RT1)、汝城白毛茶2号(RT2)和汝城白毛茶群体种(QT3)3个品系(种)的一芽二叶鲜叶按照相同的加工工艺(萎凋、干燥)加工成白茶,并探究其香气品质特征。感官定量描述法、顶空固相微萃取法和全二维气相色谱-四极杆-飞行时间质谱分析法被用于评价不同品系(种)汝城白毛茶白茶的香气属性和定性定量其挥发性成分。偏最小二乘判别分析法、相对香气活性值被用于筛选汝城白毛茶白茶的关键香气成分,并探究不同茶树汝城白毛茶品系(种)对白茶香气的影响。结果表明,3个品系(种)汝城白毛茶白茶的香气感官特征存在差异,RT1和QT3虽都有花香,但RT1清香特征显著,QT3具有毫香特征突出,RT2则呈现薄荷香。使用多元统计分析并以P<0.05、变量投影重要性值大于1和相对香气活性值大于1.00为准则,共计10种香气成分被认为是3个茶树品系(种)所制白茶香气差异的原因。苯甲醛对3个汝城白毛茶品种(系)所制白茶的清香具有关键作用。正己醛对RT1的清香形成具有关键作用。苯甲醛、芳樟醇氧化物II、芳樟醇氧化物I对RT2的薄荷香形成具有关键作用。蘑菇醇、柠檬醛和顺-4-庚烯醛对QT3的毫香具有关键作用。研究结果可为汝城白茶香型多元化及不同品系(种)的品系(种)茶关键呈香物质基础提供理论参考。 展开更多
关键词 白茶 品系(种) 全二维气相色谱-四极杆-飞行时间质谱分析法 香气 多元统计分析
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Optimization of tribological parameters over WC-12%Co laser alloyedpearlitic ductile iron using Taguchi based Grey relational analysis
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作者 N.JEYAPRAKASH YANG Che-hua TSENG Sheng-po 《Journal of Central South University》 SCIE EI CAS CSCD 2020年第3期736-751,共16页
Pearlitic ductile irons(PDIs)are used in transportation and nuclear energy industries.In heavy loading situation,the service life of PDI is affected by numerous tribo aspects.In this study,surface of the PDI is alloye... Pearlitic ductile irons(PDIs)are used in transportation and nuclear energy industries.In heavy loading situation,the service life of PDI is affected by numerous tribo aspects.In this study,surface of the PDI is alloyed with WC-12%Co powder using a high power fibre laser.The wear properties of the base material and laser alloying samples were investigated by tribometer with various parameters,i.e.,temperature,load and sliding speed.Based on experimental test,the load has maximum percentage of contribution and followed by sliding speed and working temperature.The optimized tribological parameters by Grey relational analysis(GRA)were established and those values are closely matched with predicted values.Besides,base material and laser alloying surfaces were examined through Vickers hardness machine,scanning electron microscopy(SEM)and roughness tester.The laser altered specimen shows no defects and improves the wear properties than substrates.The identified optimal tribological parameters are load of 30 N,speed of 0.5 m/s and working temperature of 300℃,and load of 30 N,speed of 0.5 m/s and working temperature of 200℃ for base metal and laser alloying samples,respectively. 展开更多
关键词 WC-12%Co laser alloying microstructure wear resistance Grey technique analysis of variance OPTIMIZATION roughness
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Joint multivariate statistical model and its applications to synthetic earthquake predic-tion 被引量:14
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作者 韩天锡 蒋淳 +2 位作者 魏雪丽 韩梅 冯德益 《地震学报》 CSCD 北大核心 2004年第5期523-528,625,共6页
针对目前地震综合预报中的一些问题,利用近30年来迅速发展的多元统计分析中主成分分析、判别分析组成多元统计组合模型,在众多的地震预报指标(预报因子)中采用信息最大化方法,选择对中期预测信息累积贡献率大于90%地震预报指标,分... 针对目前地震综合预报中的一些问题,利用近30年来迅速发展的多元统计分析中主成分分析、判别分析组成多元统计组合模型,在众多的地震预报指标(预报因子)中采用信息最大化方法,选择对中期预测信息累积贡献率大于90%地震预报指标,分别进行相关分析、预测、检验,最终应用马氏距离判别作外推综合预报;并以华北地区(30°~42°N,108°125°E)为例进行模型的应用检验,初步研究已取得了较好的效果. 展开更多
关键词 多元统计组合模型 主成分分析 判别分析 地震综合预报
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基于GC-TOF/MS技术的转Bt基因大米代谢组学研究 被引量:5
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作者 程建华 桑志红 +3 位作者 李海静 吴胜明 夏晴 董方霆 《分析测试学报》 CAS CSCD 北大核心 2016年第10期1217-1224,共8页
基于GC-TOF/MS技术对来源于两个不同产地的转Bt基因及其亲本大米进行了代谢组学研究。从大米样本中共检出774个色谱峰,鉴定出278种代谢产物,包括糖、氨基酸、脂肪酸及有机酸等代谢产物。对转Bt基因及其亲本大米进行主成分分析,结果表明,... 基于GC-TOF/MS技术对来源于两个不同产地的转Bt基因及其亲本大米进行了代谢组学研究。从大米样本中共检出774个色谱峰,鉴定出278种代谢产物,包括糖、氨基酸、脂肪酸及有机酸等代谢产物。对转Bt基因及其亲本大米进行主成分分析,结果表明,转Bt基因与亲本大米的代谢组之间无明显差异性,进一步对数据进行偏最小二乘判别分析和方差分析,仅甘油和鼠李糖两种代谢产物浓度在转Bt基因大米及其亲本大米间存在一定差异(分别升高1.55和3.32倍);考察了不同产地对大米代谢组的影响,结果表明武汉和海南两个产地的大米代谢组之间存在明显差异,有15种代谢产物在不同产地的亲本大米之间以及不同产地的转基因大米之间均发生显著变化。应用GC-TOF/MS技术对来源于不同产地的转Bt基因大米及其亲本大米的代谢组进行比较研究,结果表明引入外源Bt基因对实验中的水稻机体内代谢未产生明显影响,产地差异造成的大米间代谢组差异比引入外源Bt基因造成的大米间代谢组差异更为显著。 展开更多
关键词 转基因大米 代谢组学 差异代谢产物 多元统计分析 气相色谱-飞行时间质谱联用(GC-Tof/MS)
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基于UPLC-Q-TOF-MS技术对高盐稀态酱油发酵过程中代谢产物变化的分析 被引量:8
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作者 冯云子 黄梓堃 赵谋明 《食品科学》 EI CAS CSCD 北大核心 2021年第20期107-113,共7页
采用超高效液相色谱-四极杆飞行时间串联质谱技术,结合主成分分析和正交偏最小二乘法分析研究高盐稀态酱油发酵过程中代谢物质的变化。结果表明,发酵第90天酱油的代谢物质种类及总峰面积分别是第1天的1.47倍和6.57倍。发酵过程中共鉴定... 采用超高效液相色谱-四极杆飞行时间串联质谱技术,结合主成分分析和正交偏最小二乘法分析研究高盐稀态酱油发酵过程中代谢物质的变化。结果表明,发酵第90天酱油的代谢物质种类及总峰面积分别是第1天的1.47倍和6.57倍。发酵过程中共鉴定了155种化合物,其中含有34种显著差异代谢物质(VIP>1),包含10种氨基酸衍生物,9种脂肪酸,5种异黄酮,3种酯,2种有机酸,2种生物碱等。其中,氨基酸衍生物、异黄酮、生物碱的峰面积占所有物质总峰面积百分比分别从0.44%、6.82%、0.02%增长到20.11%、14.88%和10.81%,是酱油发酵过程中的关键差异代谢产物。本研究对酱油发酵过程中代谢规律的探索以及发酵品质调控具有重要意义。 展开更多
关键词 高盐稀态酱油 超高效液相色谱-四极杆飞行时间串联质谱 氨基酸衍生物 异黄酮 多元数据分析
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基于LC-QTOF-MS代谢组学研究甲基苯丙胺临床戒毒分期 被引量:1
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作者 王敬淇 王叶 +4 位作者 张艺 梁军成 邓艳萍 杭太俊 宋敏 《中国药科大学学报》 CAS CSCD 北大核心 2022年第3期314-322,共9页
甲基苯丙胺的滥用已成为全球公共卫生安全的一大隐患。为了更加科学可靠的判断甲基苯丙胺成瘾和戒毒阶段,本研究采用液相色谱-四极杆-飞行时间串联质谱(LC-QTOF-MS)分析技术,对甲基苯丙胺成瘾者、戒毒康复者和健康人的血浆、血清和尿中... 甲基苯丙胺的滥用已成为全球公共卫生安全的一大隐患。为了更加科学可靠的判断甲基苯丙胺成瘾和戒毒阶段,本研究采用液相色谱-四极杆-飞行时间串联质谱(LC-QTOF-MS)分析技术,对甲基苯丙胺成瘾者、戒毒康复者和健康人的血浆、血清和尿中的内源性代谢物进行分析。运用单变量和多变量统计分析处理数据,筛选符合条件的潜在生物标志物,将鉴定后的生物标志物进行代谢物富集分析,寻找代谢物与代谢途径之间的联系。多变量统计结果表明,甲基苯丙胺急性期组、康复期组和健康组3组聚类分离明显;在血清、血浆和尿液中分别鉴定出3,18和6个差异代谢物,提示甲基苯丙胺急性期组脂质代谢异常,康复期组脂肪酸代谢、硫酸盐/亚硫酸盐代谢和性激素代谢异常。本研究筛选出的潜在生物标志物,为甲基苯丙胺临床戒毒分期提供科学依据。 展开更多
关键词 甲基苯丙胺 LC-QTof-MS 多变量分析 生物标志物 临床戒毒分期
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UPLC-Q-TOF/MS法鉴定不同基原水柏枝的化学成分 被引量:3
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作者 武鑫玥 丁银 +5 位作者 赵程成 苟晓玲 赵紫薇 张静 唐策 范刚 《中成药》 CAS CSCD 北大核心 2023年第11期3656-3662,共7页
目的鉴定不同基原水柏枝的化学成分,筛选种间差异成分。方法采用UPLC-Q-TOF/MS法定性分析水柏枝药材中的化学成分,结合偏最小二乘法判别分析和方差分析筛选种间差异成分。结果从中得到36个化合物,包括6个黄酮类、17个酚酸类、2个生物碱... 目的鉴定不同基原水柏枝的化学成分,筛选种间差异成分。方法采用UPLC-Q-TOF/MS法定性分析水柏枝药材中的化学成分,结合偏最小二乘法判别分析和方差分析筛选种间差异成分。结果从中得到36个化合物,包括6个黄酮类、17个酚酸类、2个生物碱类、3个氨基酸、8个其他类。首次发现4个品种(秀丽水柏枝Myricariae elegans、具鳞水柏枝M.squamosa、三春水柏枝M.paniculata、小花水柏枝M.wardii)之间的差异标志物为水柏枝素A、阿福豆苷、对羟基桂皮酸、3,4-二甲氧基没食子酸、没食子酸甲酯、2,4,6-三羟基苯甲酸甲酯、香草酸甲酯。结论该方法准确可行,可用于鉴定不同基原水柏枝药材的化学成分差异,为其品种鉴别和临床应用提供参考。 展开更多
关键词 水柏枝 化学成分 品种鉴定 UPLC-Q-Tof/MS 偏最小二乘法判别分析 方差分析
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Prediction and optimization of process parameter of friction stir welded AA5083-H111 aluminum alloy using response surface methodology 被引量:26
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作者 R.Palanivel P.Koshy Mathews 《Journal of Central South University》 SCIE EI CAS 2012年第1期1-8,共8页
A systematic approach was presented to develop the empirical model for predicting the ultimate tensile strength of AA5083-H111 aluminum alloy which is widely used in ship building industry by incorporating friction st... A systematic approach was presented to develop the empirical model for predicting the ultimate tensile strength of AA5083-H111 aluminum alloy which is widely used in ship building industry by incorporating friction stir welding(FSW) process parameters such as tool rotational speed,welding speed,and axial force.FSW was carried out considering three-factor five-level central composite rotatable design with full replications technique.Response surface methodology(RSM) was applied to developing linear regression model for establishing the relationship between the FSW process parameters and ultimate tensile strength.Analysis of variance(ANOVA) technique was used to check the adequacy of the developed model.The FSW process parameters were also optimized using response surface methodology(RSM) to maximize the ultimate tensile strength.The joint welded at a tool rotational speed of 1 000 r/min,a welding speed of 69 mm/min and an axial force of 1.33 t exhibits higher tensile strength compared with other joints. 展开更多
关键词 friction stir welding design expert design of experiments analysis of variance (ANOVA) response surfacemethodology (RSM) optimization
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Recent developments on applications of sequential loop closing and diagonal dominance control schemes to industrial multivariable system 被引量:4
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作者 A.H.Mazinan M.F.Kazemi 《Journal of Central South University》 SCIE EI CAS 2013年第12期3401-3420,共20页
With a focus on an industrial multivariable system, two subsystems including the flow and the level outputs are analysed and controlled, which have applicability in both real and academic environments. In such a case,... With a focus on an industrial multivariable system, two subsystems including the flow and the level outputs are analysed and controlled, which have applicability in both real and academic environments. In such a case, at first, each subsystem is distinctively represented by its model, since the outcomes point out that the chosen models have the same behavior as corresponding ones. Then, the industrial multivariable system and its presentation are achieved in line with the integration of these subsystems, since the interaction between them can not actually be ignored. To analyze the interaction presented, the Gershgorin bands need to be acquired, where the results are used to modify the system parameters to appropriate values. Subsequently, in the view of modeling results, the control concept in two different techniques including sequential loop closing control(SLCC) scheme and diagonal dominance control(DDC) schemes is proposed to implement on the system through the Profibus network, as long as the OPC(OLE for process control) server is utilized to communicate between the control schemes presented and the multivariable system. The real test scenarios are carried out and the corresponding outcomes in their present forms are acquired. In the same way, the proposed control schemes results are compared with each other, where the real consequences verify the validity of them in the field of the presented industrial multivariable system control. 展开更多
关键词 multivariable system diagonal dominance control sequential loop closing control Profibus network OPC server orifice relation interaction analysis Gershogerin bands non-minimum phase system
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基于UPLC-QTOF-MS结合非靶向代谢组学鉴别3种江西名茶 被引量:22
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作者 徐春晖 王远兴 《食品科学》 EI CAS CSCD 北大核心 2022年第2期316-323,共8页
利用超高效液相色谱-四极杆飞行时间质谱仪建立一种狗牯脑、庐山云雾茶和婺源绿茶品质鉴别的非靶向代谢组学分析方法。利用MassHunter Mass Profile对原始数据进行逐步筛选,最终确定220个特征差异化合物,并对其进行主成分分析和聚类分析... 利用超高效液相色谱-四极杆飞行时间质谱仪建立一种狗牯脑、庐山云雾茶和婺源绿茶品质鉴别的非靶向代谢组学分析方法。利用MassHunter Mass Profile对原始数据进行逐步筛选,最终确定220个特征差异化合物,并对其进行主成分分析和聚类分析,结果表明3种茶叶具有较大差异。构建偏最小二乘判别分析预测模型,该模型能够对狗牯脑、庐山云雾茶和婺源绿茶品质进行鉴别,准确度达100%。通过一级母离子和二级碎片离子对220种特征差异物进行鉴定,最终鉴定出22种,主要成分为黄酮类、糖苷衍生物和有机酸类等,结合热图分析发现其在3种江西名茶中的含量具有明显差异。本研究对茶叶品质鉴别具有一定指导意义,该方法可广泛用于食品的分析和表征。 展开更多
关键词 江西名茶 品质鉴别 超高效液相色谱-四极杆飞行时间质谱 非靶向代谢组学 多元统计分析
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Influence of process parameters on deep drawing of AA6111 aluminum alloy at elevated temperatures 被引量:8
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作者 马闻宇 王宝雨 +2 位作者 傅垒 周靖 黄鸣东 《Journal of Central South University》 SCIE EI CAS CSCD 2015年第4期1167-1174,共8页
To gain a deep insight into the hot drawing process of aluminum alloy sheet, simulations of cylindrical cup drawing at elevated temperatures were carried out with experimental validation. The influence of four importa... To gain a deep insight into the hot drawing process of aluminum alloy sheet, simulations of cylindrical cup drawing at elevated temperatures were carried out with experimental validation. The influence of four important process parameters, namely,punch velocity, blank holder force(BHF), friction coefficient and initial forming temperature of blank on drawing characteristics(i.e.minimum thickness and thickness deviation) was investigated with the help of design of experiments(DOE), analysis of variance(ANOVA) and analysis of mean(ANOM). Based on the results of ANOVA, it is shown that the blank holder force has the greatest influence on minimum thickness. The importance of punch velocity for thickness deviation is 44.35% followed by BHF of 24.88%,friction coefficient of 15.77% and initial forming temperature of blank of 14.995%. After determining the significance of each factor on forming characteristics, how the individual parameter affects characteristics was further analyzed by ANOM. 展开更多
关键词 aluminum process parameters finite element method hot drawing analysis of variance analysis of mean
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基于UPLC-Q-TOF-MS/MS和网络药理学的半夏炮制前后差异性物质基础及功效分析 被引量:6
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作者 石琨群 熊玥 +4 位作者 钱香 朱育凤 姚毅 张倩 刘史佳 《南京中医药大学学报》 CAS CSCD 北大核心 2024年第2期153-166,共14页
目的基于超高效液相色谱-四极杆-飞行时间质谱(UPLC-Q-TOF-MS/MS)和多变量统计分析,筛选并鉴定半夏及其不同炮制品的差异性物质基础,并针对共有及差异性物质基础进行网络药理学分析,挖掘半夏炮制前后物质基础与功效变化的关系。方法采用... 目的基于超高效液相色谱-四极杆-飞行时间质谱(UPLC-Q-TOF-MS/MS)和多变量统计分析,筛选并鉴定半夏及其不同炮制品的差异性物质基础,并针对共有及差异性物质基础进行网络药理学分析,挖掘半夏炮制前后物质基础与功效变化的关系。方法采用UPLC-Q-TOF-MS/MS检测半夏及其炮制品共42批样品的主要物质基础并筛选差异性成分,运用正交偏最小二乘判别分析(OPLS-DA),以VIP>1.5、P<0.01、FC>2或<0.5为筛选标准,通过数据库配对、文献比对鉴定得到差异性成分。进一步通过TCMIP数据库对差异性物质基础检索靶点,对靶点进行蛋白互作分析,最后通过GO富集和KEGG富集分析其代谢通路。结果生半夏与法半夏有14个差异性成分,与生半夏相比,法半夏含量升高的成分主要有甘草酸、甘草次酸、甘草素等,含量降低的成分主要为酰胺类。生半夏与姜半夏有18个差异性成分,主要为核苷类、黄酮类、氨基酸类。鸟苷、黄嘌呤及酪氨酸等含量降低,磷酸腺苷含量升高。生半夏与清半夏有18个差异性成分,清半夏中多种成分相对含量均降低,如鞘氨醇。得到生半夏67个核心靶点,法半夏45个核心靶点,姜半夏38个核心靶点。结论建立的UPLC-Q-TOF-MS/MS方法能够较好地分离鉴定半夏中的化学成分,结合多变量统计分析和网络药理学,分析半夏及其炮制品的物质基础及潜在作用机制,可为研究作用靶点提供思路,为半夏及其炮制品的临床合理应用提供数据支持。 展开更多
关键词 半夏 炮制品 差异性物质基础 多变量统计分析 网络药理学
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Influence of Al_2O_3 particles on the microstructure and mechanical properties of copper surface composites fabricated by friction stir processing 被引量:2
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作者 L.SUVARNA RAJU A.KUMAR 《Defence Technology(防务技术)》 SCIE EI CAS 2014年第4期375-383,共9页
The influence of three factors, such as volume percentage of reinforcement particles(i.e. Al2O3), tool tilt angle and concave angle of shoulder, on the mechanical properties of Cue Al2O3 surface composites fabricated ... The influence of three factors, such as volume percentage of reinforcement particles(i.e. Al2O3), tool tilt angle and concave angle of shoulder, on the mechanical properties of Cue Al2O3 surface composites fabricated via friction stir processing was studied. Taguchi method was used to optimize these factors for maximizing the mechanical properties of surface composites. The fabricated surface composites were examined by optical microscope for dispersion of reinforcement particles. It was found that Al2O3 particles are uniformly dispersed in the stir zone. The tensile properties of the surface composites increased with the increase in the volume percentage of the Al2O3 reinforcement particles.This is due to the addition of the reinforcement particles which increases the temperature of recrystallization by pinning the grain boundaries of the copper matrix and blocking the movement of the dislocations. The observed mechanical properties are correlated with microstructure and fracture features. 展开更多
关键词 表面复合材料 材料力学性能 颗粒 搅拌 制造 摩擦 Taguchi法 微观
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Experimental study of the effect of wear parameters on the wear behavior of A356 alloy/cow horn particulate composites
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作者 B.Q.Ochieze C.C.Nwobi-Okoye P.N.Atamuo 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2018年第1期77-82,共6页
Experimental study of the effect of wear parameters on the wear behaviour of A356 alloy reinforced with cow horn particles(CHp) produced by spark plasma sintering was investigated. Experiments were conducted based on ... Experimental study of the effect of wear parameters on the wear behaviour of A356 alloy reinforced with cow horn particles(CHp) produced by spark plasma sintering was investigated. Experiments were conducted based on the plan of experiments generated through Taguchi's(L9) technique. Tribometer was used for the wear test and Scanning electron microscope was used to analyse the worn scar of the samples. The results shows that, A356 alloy reinforced with CHp exhibited better dry sliding wear resistance than the unreinforced alloy. Wear rate decreased as the amount of CHp reinforcement increased in the matrix. It was found that, the optimum level of the factors with minimized the wear loss were obtained at: wt%CHp(20%), applied load(10 N), sliding velocity(3 m/s) and sliding distance(2000 m). It can be seen that the wear track of the sample are(D ? 0.81 and L = 42.85 mm) and(D ? 0.54 and L= 27.03 mm) for A356 alloy and composites at optimum condition respectively. The results showed that the addition of cow horn particles as reinforcing materials in A356 alloy composites increased the wear resistance of the composites greatly. 展开更多
关键词 A356alloy COW HORN PARTICLES Microstructure analysis of variance and WEAR behaviour
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基于UPLC-Q-TOF-MS/MS结合多元统计方法的不同产地布渣叶药材质量评价 被引量:1
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作者 刘焰嫦 肖观林 +4 位作者 汤瑞茵 曾志浩 吴广颖 贾德政 毕晓黎 《分析测试学报》 CAS CSCD 北大核心 2024年第11期1784-1793,共10页
应用超高效液相色谱-四极杆-飞行时间串联质谱(UPLC-Q-TOF-MS/MS)技术,结合多元统计分析对不同产地的布渣叶药材进行质量差异分析,为布渣叶的产地判别和质量评价提供依据。采用UPLC-QTOF-MS/MS对不同产地的布渣叶样品进行全成分分析,应... 应用超高效液相色谱-四极杆-飞行时间串联质谱(UPLC-Q-TOF-MS/MS)技术,结合多元统计分析对不同产地的布渣叶药材进行质量差异分析,为布渣叶的产地判别和质量评价提供依据。采用UPLC-QTOF-MS/MS对不同产地的布渣叶样品进行全成分分析,应用主成分分析(PCA)、正交偏最小二乘法-判别分析(OPLS-DA)及聚类分析(CA)对云南昆明、广西玉林和广东阳江3个产地共18批次布渣叶药材进行多元统计分析,以变量重要性投影(VIP>1)和t检验结果(P<0.05)为筛选标准,确定不同产地布渣叶药材中具有显著差异的化学成分。从不同产地布渣叶药材中共鉴定出53个化学成分,以黄酮类、原花青素类、有机酸和生物碱等类型化合物为主,其中N-反式香豆酰酪胺、N-反式阿魏酰酪胺为首次在布渣叶药材中报道。不同产地布渣叶的化学成分差异明显,共鉴定出17个差异化学成分,其含量在不同产地呈现不同的变化规律,可作为产地鉴别的依据。 展开更多
关键词 布渣叶 UPLC-Q-Tof-MS/MS 多元统计学 产地差异 质量评价
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裂区试验设计CASIOfx-4500p分析程序
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作者 汪传佳 毛斌 +1 位作者 余建华 余士香 《浙江林业科技》 北大核心 1995年第5期64-68,共5页
利用CASIOfx-4500p计算器编程进行裂区试验设计方差分析和多重比较,准确快捷。
关键词 林业 裂区试验 方差分析 程序 计算器
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