期刊文献+
共找到254,672篇文章
< 1 2 250 >
每页显示 20 50 100
基于UHPLC-Q-Orbitrap HRMS法分析曼地亚红豆杉炮制前后差异性化学成分 被引量:2
1
作者 李雅静 王胜超 +5 位作者 张振凌 朱建光 院军 吴亚宁 郭幸 张帅 《中华中医药学刊》 北大核心 2025年第4期116-128,I0027,I0028,共15页
目的为探究曼地亚红豆杉炮制前后差异性化学成分。方法采用超高效液相色谱串联四极杆静电场轨道阱高分辨质谱法(UHPLC-Q-Orbitrap HRMS)对曼地亚红豆杉中化学成分进行鉴定,根据高分辨质谱精确分子量及碎片离子信息、对照品、文献、在线... 目的为探究曼地亚红豆杉炮制前后差异性化学成分。方法采用超高效液相色谱串联四极杆静电场轨道阱高分辨质谱法(UHPLC-Q-Orbitrap HRMS)对曼地亚红豆杉中化学成分进行鉴定,根据高分辨质谱精确分子量及碎片离子信息、对照品、文献、在线数据库等对化学成分进行鉴定,并以炮制前后各成分的离子峰面积比作为炮制前后的变化指数进行对比;利用SIMCA软件建立曼地亚红豆杉不同炮制品的主成分分析(PCA)和正交偏最小二乘法判别分析(OPLS-DA)模型,获得PCA图、OPLS-DA图和变量重要性投影(VIP)值,筛选曼地亚红豆杉炮制前后的差异性成分。结果共鉴定出74个成分,曼地亚红豆杉生品74个成分、酒炙品70个成分、酒浸品70个成分、酒洗品71个成分、酒蒸品71个成分、醋浸品71个成分、醋炒品71个成分、醋蒸品71个成分、蜜炙品72个成分、姜炙品70个成分。其中,18个成分通过与对照品比对鉴定。经PCA,发现不同炮制方法对曼地亚红豆杉的化学成分具有明显的差异,OPLS-DA筛选出VIP值>1的38个化学成分作为不同炮制方法的主要差异性成分。结论方法快速准确,可用于测定曼地亚红豆杉炮制前后的化学成分差异,通过比较化学成分差异可为临床疗效研究提供重要参考。 展开更多
关键词 曼地亚红豆杉 炮制 UHPLC-Q-Orbitrap hrmS 化学成分 多元统计分析
在线阅读 下载PDF
UHPLC-Q-Orbitrap HRMS法分析健脾扶正颗粒化学成分及入血成分
2
作者 杨琼梁 孔祥柏 +5 位作者 张小娟 张旭 潘娟 聂格 李足意 欧阳文 《中成药》 北大核心 2025年第6期2078-2089,共12页
目的 分析健脾扶正颗粒化学成分及入血成分。方法 采用ACQUITY UPLC HSS T3(2.1 mm×100 mm, 1.8μm)反相色谱柱;流动相水(含0.1%甲酸)-乙腈,梯度洗脱;体积流量0.3 mL/min;柱温40℃;进样量6.0μL;加热电喷雾离子源;正负离子扫描;结... 目的 分析健脾扶正颗粒化学成分及入血成分。方法 采用ACQUITY UPLC HSS T3(2.1 mm×100 mm, 1.8μm)反相色谱柱;流动相水(含0.1%甲酸)-乙腈,梯度洗脱;体积流量0.3 mL/min;柱温40℃;进样量6.0μL;加热电喷雾离子源;正负离子扫描;结合对照品、文献及数据库进行化学成分鉴定。结果 从中共鉴定出164种化学成分,包括35种皂苷类、33种苯丙素类、40种黄酮类、13种萜类、9种有机酸类、4种氨基酸类、4种生物碱类、4种低聚糖、4种核苷类、2种炔苷类、4种环肽类、3种酚类及9种其他类。含药血清中中共鉴定出21种化学成分,包括5种原型化合物和16种代谢物。结论 该方法准确稳定,可为健脾扶正颗粒后续药效物质基础、质量研究及临床应用提供数据支撑。 展开更多
关键词 健脾扶正颗粒 化学成分 入血成分 分离鉴定 UHPLC-Q-Orbitrap hrmS
在线阅读 下载PDF
基于HRM技术开发水稻抗条纹叶枯病基因STV11功能标记
3
作者 王婵 吴莹莹 +4 位作者 李文奇 李霞 王芳权 周彤 杨杰 《作物学报》 北大核心 2025年第9期2547-2556,共10页
水稻条纹叶枯病是一种由灰飞虱传播的重要病害,对水稻(Oryza sativa L.)生产造成威胁,其病原为水稻条纹叶枯病毒(rice stripe virus,RSV)。为了加快水稻条纹叶枯病抗性品种选育进程,本研究旨在开发可以快速准确鉴定水稻条纹叶枯病抗性... 水稻条纹叶枯病是一种由灰飞虱传播的重要病害,对水稻(Oryza sativa L.)生产造成威胁,其病原为水稻条纹叶枯病毒(rice stripe virus,RSV)。为了加快水稻条纹叶枯病抗性品种选育进程,本研究旨在开发可以快速准确鉴定水稻条纹叶枯病抗性基因的功能标记,有助于提高水稻种质改良的效率。STV11是从籼稻Kasalath中鉴定的条纹叶枯病抗性基因。根据Kasalath型条纹叶枯病基因STV11KAS的6个碱基缺失的功能性多态性序列差异,通过NCBI查找克隆序列(登录号:LOC_Os11g30910),针对其第773~779位核苷酸在抗感品种上的差异序列,设计基于高分辨率熔解曲线(high-resolution melting curve,HRM)的功能性分子标记stvHRM-3。进一步,对所检测品种的目标片段的PCR产物进行测序分析以验证鉴定结果,并对部分江苏省试验品种进行抗条纹叶枯病表型和基因型的分析。通过HRM-PCR检测结合测序分析,筛选了STV11基因1个功能区域的功能标记stvHRM-3。利用stvHRM-3对包括江苏省晚粳组区试、迟熟中粳预试材料以及育种中间材料、部分品种资源等在内的520份粳稻材料的STV11基因型进行检测。结果发现,217份水稻材料为抗病基因型;294份材料为感病基因型;9份材料为抗感杂合基因型。基于功能标记鉴定为抗病基因型的材料均表现出高抗或抗病表型特征。基于HRM-PCR技术开发的基因功能标记stvHRM-3可以快速高通量鉴定水稻STV11不同基因型,具有潜在的育种应用价值。 展开更多
关键词 水稻 条纹叶枯病 STV11基因 功能标记 hrm-PCR技术
在线阅读 下载PDF
DART-Orbitrap HRMS法快速筛查及确证化妆品中22种化学防晒剂 被引量:1
4
作者 卓兴旭 蒋丹艺 +4 位作者 刘媛 宫旭 尚姝 冯有龙 孙晶 《质谱学报》 北大核心 2025年第5期637-648,I0005,共13页
本研究建立了一种实时直接分析(DART)离子源结合静电场轨道阱高分辨质谱(Orbitrap HRMS)快速筛查及确证22种化学防晒剂的方法。样品经甲醇-四氢呋喃-水溶液(25:45:30,V/V/V)提取,以80%甲醇稀释后,采用DART-Orbitrap HRMS检测。进样模块... 本研究建立了一种实时直接分析(DART)离子源结合静电场轨道阱高分辨质谱(Orbitrap HRMS)快速筛查及确证22种化学防晒剂的方法。样品经甲醇-四氢呋喃-水溶液(25:45:30,V/V/V)提取,以80%甲醇稀释后,采用DART-Orbitrap HRMS检测。进样模块样品传输速度0.5 mm/s,DART离子源采用氦气反应模式,离子化温度500℃,栅极电压400 V。高分辨质谱采用正、负离子同时采集的全扫描-数据依赖性二级质谱扫描。结果表明,本方法专属性良好,化妆品基质无干扰,灵敏度高,22种防晒剂的检测限为0.04~4μg/g。在实际样品测定中,甲氧基肉桂酸乙基己酯的检出率最高,15批防晒产品有3批未检出标签标识的目标防晒剂,其余样品均检出1~6种化学防晒剂;6批彩妆产品中有3批检出甲氧基肉桂酸乙基己酯。本方法前处理简单、分析速度快、定性准确、检测通量大、环境污染小,其样品测定结果与高效液相色谱法一致,能够满足化妆品中化学防晒剂的快速筛查要求。. 展开更多
关键词 实时直接分析(DART) 静电场轨道阱高分辨质谱(Orbitrap hrmS) 防晒剂 快速筛查 化妆品 二苯酮-3 3-亚苄基樟脑
在线阅读 下载PDF
基于UHPLC-Q-Orbitrap-HRMS技术比较金银花与忍冬枝条的化学成分 被引量:1
5
作者 陈林 黄涵 +3 位作者 赵培敬 李中娥 宋颖 方朝清 《分析测试学报》 北大核心 2025年第4期645-651,共7页
该文基于超高效液相色谱-四极杆/静电场轨道阱高分辨质谱(UHPLC-Q-Orbitrap-HRMS)技术比较金银花与忍冬枝条的化学成分。首先通过高效液相色谱(HPLC)技术结合指纹图谱分析不同采收期忍冬枝条与金银花的化学成分相似度,结果表明10月底采... 该文基于超高效液相色谱-四极杆/静电场轨道阱高分辨质谱(UHPLC-Q-Orbitrap-HRMS)技术比较金银花与忍冬枝条的化学成分。首先通过高效液相色谱(HPLC)技术结合指纹图谱分析不同采收期忍冬枝条与金银花的化学成分相似度,结果表明10月底采收的忍冬枝条与金银花的相似度最高,达到85%。然后在电喷雾正、负电离模式下,采用UHPLC-Q-Orbitrap-HRMS技术对10月底采收的忍冬枝条与金银花提取物进行全扫描及二级质谱扫描,通过与对照品比较、在线数据库匹配及文献检索,共鉴定出38种化学成分,其中35种为共有成分。将35种共有成分的质谱数据导入MetaboAnalyst网站,基于偏最小二乘分析算法计算变量投影重要性(VIP)分析值,结果有8个化合物的VIP>1,表明10月底采收的忍冬枝条与金银花的化学成分相似度较高,差异性主要体现在部分成分的含量上。该研究可为忍冬枝条资源的合理开发利用提供有效的数据支撑。 展开更多
关键词 UHPLC-Q-Orbitrap-hrmS 金银花 忍冬枝条 化学成分
在线阅读 下载PDF
Combing the Entropy Weight Method with Fuzzy Mathematics for Assessing the Quality and Post-Ripening Mechanism of High-Temperature Daqu during Storage 被引量:1
6
作者 YANG Junlin YANG Shaojuan +8 位作者 WU Cheng YIN Yanshun YOU Xiaolong ZHAO Wenyu ZHU Anran WANG Jia HU Feng HU Jianfeng WANG Diqiang 《食品科学》 北大核心 2025年第9期48-62,共15页
This study investigated the physicochemical properties,enzyme activities,volatile flavor components,microbial communities,and sensory evaluation of high-temperature Daqu(HTD)during the maturation process,and a standar... This study investigated the physicochemical properties,enzyme activities,volatile flavor components,microbial communities,and sensory evaluation of high-temperature Daqu(HTD)during the maturation process,and a standard system was established for comprehensive quality evaluation of HTD.There were obvious changes in the physicochemical properties,enzyme activities,and volatile flavor components at different storage periods,which affected the sensory evaluation of HTD to a certain extent.The results of high-throughput sequencing revealed significant microbial diversity,and showed that the bacterial community changed significantly more than did the fungal community.During the storage process,the dominant bacterial genera were Kroppenstedtia and Thermoascus.The correlation between dominant microorganisms and quality indicators highlighted their role in HTD quality.Lactococcus,Candida,Pichia,Paecilomyces,and protease activity played a crucial role in the formation of isovaleraldehyde.Acidic protease activity had the greatest impact on the microbial community.Moisture promoted isobutyric acid generation.Furthermore,the comprehensive quality evaluation standard system was established by the entropy weight method combined with multi-factor fuzzy mathematics.Consequently,this study provides innovative insights for comprehensive quality evaluation of HTD during storage and establishes a groundwork for scientific and rational storage of HTD and quality control of sauce-flavor Baijiu. 展开更多
关键词 microbial community high-temperature Daqu comprehensive quality evaluation entropy weight method maturation process
在线阅读 下载PDF
基于UHPLC-Q-Orbitrap HRMS分析干葛散化学成分
7
作者 张小娟 张旭 +1 位作者 李足意 杨琼梁 《中成药》 北大核心 2025年第11期3853-3863,共11页
目的基于UHPLC-Q-Orbitrap HRMS对干葛散的化学成分进行分析鉴定。方法分析采用ACQUITY UPLC HSS T3反相色谱柱(2.1 mm×100 mm,1.8μm);流动相水(0.1%甲酸)-乙腈,梯度洗脱;体积流量0.3 mL/min;柱温40℃;进样量6.0μL;正、负离子扫... 目的基于UHPLC-Q-Orbitrap HRMS对干葛散的化学成分进行分析鉴定。方法分析采用ACQUITY UPLC HSS T3反相色谱柱(2.1 mm×100 mm,1.8μm);流动相水(0.1%甲酸)-乙腈,梯度洗脱;体积流量0.3 mL/min;柱温40℃;进样量6.0μL;正、负离子扫描;扫描范围m/z:100~1500。根据精确质荷比和二级碎片离子信息,结合文献、数据库鉴定干葛散的化学成分。结果共鉴定出154种化学成分,包括黄酮类、生物碱类、萜类、酚酸类、苯丙素类、糖类、苯乙醇苷类、氨基酸类等。结论该方法能快速、高效地鉴定干葛散的化学成分,为干葛散的质量控制和临床应用提供科学依据。 展开更多
关键词 干葛散 化学成分 UHPLC-Q-Orbitrap hrmS 质量控制
在线阅读 下载PDF
An improved efficient adaptive method for large-scale multiexplosives explosion simulations
8
作者 Tao Li Cheng Wang Baojun Shi 《Defence Technology(防务技术)》 2025年第3期28-47,共20页
Shock wave caused by a sudden release of high-energy,such as explosion and blast,usually affects a significant range of areas.The utilization of a uniform fine mesh to capture sharp shock wave and to obtain precise re... Shock wave caused by a sudden release of high-energy,such as explosion and blast,usually affects a significant range of areas.The utilization of a uniform fine mesh to capture sharp shock wave and to obtain precise results is inefficient in terms of computational resource.This is particularly evident when large-scale fluid field simulations are conducted with significant differences in computational domain size.In this work,a variable-domain-size adaptive mesh enlargement(vAME)method is developed based on the proposed adaptive mesh enlargement(AME)method for modeling multi-explosives explosion problems.The vAME method reduces the division of numerous empty areas or unnecessary computational domains by adaptively suspending enlargement operation in one or two directions,rather than in all directions as in AME method.A series of numerical tests via AME and vAME with varying nonintegral enlargement ratios and different mesh numbers are simulated to verify the efficiency and order of accuracy.An estimate of speedup ratio is analyzed for further efficiency comparison.Several large-scale near-ground explosion experiments with single/multiple explosives are performed to analyze the shock wave superposition formed by the incident wave,reflected wave,and Mach wave.Additionally,the vAME method is employed to validate the accuracy,as well as to investigate the performance of the fluid field and shock wave propagation,considering explosive quantities ranging from 1 to 5 while maintaining a constant total mass.The results show a satisfactory correlation between the overpressure versus time curves for experiments and numerical simulations.The vAME method yields a competitive efficiency,increasing the computational speed to 3.0 and approximately 120,000 times in comparison to AME and the fully fine mesh method,respectively.It indicates that the vAME method reduces the computational cost with minimal impact on the results for such large-scale high-energy release problems with significant differences in computational domain size. 展开更多
关键词 Large-scale explosion Shock wave Adaptive method Fluid field simulations Efficient method
在线阅读 下载PDF
A New Technique for Constructing Higher-order Iterative Methods to Solve Nonlinear Systems
9
作者 XIAO Xiaoyong 《应用数学》 北大核心 2025年第3期762-774,共13页
In this paper,a new technique is introduced to construct higher-order iterative methods for solving nonlinear systems.The order of convergence of some iterative methods can be improved by three at the cost of introduc... In this paper,a new technique is introduced to construct higher-order iterative methods for solving nonlinear systems.The order of convergence of some iterative methods can be improved by three at the cost of introducing only one additional evaluation of the function in each step.Furthermore,some new efficient methods with a higher-order of convergence are obtained by using only a single matrix inversion in each iteration.Analyses of convergence properties and computational efficiency of these new methods are made and testified by several numerical problems.By comparison,the new schemes are more efficient than the corresponding existing ones,particularly for large problem sizes. 展开更多
关键词 Systems of nonlinear equation Order of convergence Higher-order method Extended Newton iteration Computational efficiency
在线阅读 下载PDF
An efficient and accurate numerical method for simulating close-range blast loads of cylindrical charges based on neural network
10
作者 Ting Liu Changhai Chen +2 位作者 Han Li Yaowen Yu Yuansheng Cheng 《Defence Technology(防务技术)》 2025年第2期257-271,共15页
To address the problems of low accuracy by the CONWEP model and poor efficiency by the Coupled Eulerian-Lagrangian(CEL)method in predicting close-range air blast loads of cylindrical charges,a neural network-based sim... To address the problems of low accuracy by the CONWEP model and poor efficiency by the Coupled Eulerian-Lagrangian(CEL)method in predicting close-range air blast loads of cylindrical charges,a neural network-based simulation(NNS)method with higher accuracy and better efficiency was proposed.The NNS method consisted of three main steps.First,the parameters of blast loads,including the peak pressures and impulses of cylindrical charges with different aspect ratios(L/D)at different stand-off distances and incident angles were obtained by two-dimensional numerical simulations.Subsequently,incident shape factors of cylindrical charges with arbitrary aspect ratios were predicted by a neural network.Finally,reflected shape factors were derived and implemented into the subroutine of the ABAQUS code to modify the CONWEP model,including modifications of impulse and overpressure.The reliability of the proposed NNS method was verified by related experimental results.Remarkable accuracy improvement was acquired by the proposed NNS method compared with the unmodified CONWEP model.Moreover,huge efficiency superiority was obtained by the proposed NNS method compared with the CEL method.The proposed NNS method showed good accuracy when the scaled distance was greater than 0.2 m/kg^(1/3).It should be noted that there is no need to generate a new dataset again since the blast loads satisfy the similarity law,and the proposed NNS method can be directly used to simulate the blast loads generated by different cylindrical charges.The proposed NNS method with high efficiency and accuracy can be used as an effective method to analyze the dynamic response of structures under blast loads,and it has significant application prospects in designing protective structures. 展开更多
关键词 Close-range air blast load Cylindrical charge Numerical method Neural network CEL method CONWEP model
在线阅读 下载PDF
Design and optimization of the RGB beam combiner in micro display using entropy weight-TOPSIS method
11
作者 ZHENG Yu ZHAO Yan-bing +4 位作者 ZOU Xin-jie WANG Ji-rong JIANG Xiang LIU Jian-zhe DUAN Ji-an 《Journal of Central South University》 2025年第2期483-494,共12页
Red-green-blue(RGB)beam combiners are widely used in scenarios such as augmented reality/virtual reality(AR/VR),laser projection,biochemical detection,and other fields.Optical waveguide combiners have attracted extens... Red-green-blue(RGB)beam combiners are widely used in scenarios such as augmented reality/virtual reality(AR/VR),laser projection,biochemical detection,and other fields.Optical waveguide combiners have attracted extensive attention due to their advantages of small size,high multiplexing efficiency,convenient mass production,and low cost.An RGB beam combiner based on directional couplers is designed,with a core-cladding relative refractive index difference of 0.75%.The RGB beam combiner is optimized from the perspective of parameter optimization.Using the beam propagation method(BPM),the relationship between the performance of the RGB beam combiner and individual parameters is studied,achieving preliminary optimization of the device’s performance.The key parameters of the RGB beam combiner are optimized using the entropy weight-technique for order preference by similarity to an ideal solution TOPSIS method,establishing the optimal parameter scheme and further improving the device’s performance indicators.The results show that after optimization,the multiplexing efficiencies for red,green,and blue lights,as well as the average multiplexing efficiency,reached 99.17%,99.76%,96.63%and 98.52%,respectively.The size of the RGB beam combiner is 4.768 mm×0.062 mm. 展开更多
关键词 optical waveguide combiners red-green-blue beam combiner beam propagation method entropy weight TOPSIS method multiplexing efficiency
在线阅读 下载PDF
Research on Denoising Method of Agricultural Product Terahertz Spectroscopy Based on Adaptive Signal Decomposition
12
作者 WU Jing-zhu LIU Yu-hao +3 位作者 YANG Yi XIE Chuan-luan L Zhong-ming LI Yi-can 《光谱学与光谱分析》 北大核心 2025年第12期3575-3584,共10页
To address the issues of peak overlap caused by complex matrices in agricultural product terahertz(THz)spectral signals and the dynamic,nonlinear interference induced by environmental and system noise,this study explo... To address the issues of peak overlap caused by complex matrices in agricultural product terahertz(THz)spectral signals and the dynamic,nonlinear interference induced by environmental and system noise,this study explores the feasibility of adaptive-signal-decomposition-based denoising methods to improve THz spectral quality.THz time-domain spectroscopy(THz-TDS)combined with an attenuated total reflection(ATR)accessory was used to collect THz absorbance spectra from 48 peanut samples.Taking the quantitative prediction model of peanut moisture content based on THz-ATR as an example,wavelet transform(WT),empirical mode decomposition(EMD),local mean decomposition(LMD),and its improved methods-segmented local mean decomposition(SLMD)and piecewise mirror extension local mean decomposition(PME-LMD)-were employed for spectral denoising.The applicability of different denoising methods was evaluated using a support vector regression(SVR)model.Experimental results show that the peanut moisture content prediction model constructed after PME-LMD denoising achieved the best performance,with a root mean square error(RMSE),coefficient of determination(R^(2)),and mean absolute percentage error(MAPE)of 0.010,0.912,and 0.040,respectively.Compared with traditional methods,PME-LMD significantly improved spectral quality and model prediction performance.The PME-LMD denoising strategy proposed in this study effectively suppresses non-uniform noise interference in THz spectral signals,providing an efficient and accurate preprocessing method for THz spectral analysis of agricultural products.This research provides theoretical support and technical guidance for the application of THz technology for detecting agricultural product quality. 展开更多
关键词 Terahertz spectroscopy Denoising method Agricultural products Support vector regression Piecewise mirror extension local mean decomposition
在线阅读 下载PDF
基于UPLC-Q-Orbitrap HRMS强力五虎合剂的化学成分分析
13
作者 王艳平 李新爱 +3 位作者 张燕娣 李丽霞 宁娱 田杰 《辽宁中医杂志》 北大核心 2025年第9期130-137,共8页
目的基于超高效液相色谱-四极杆-静电场轨道阱高分辨质谱法(UPLC-Q-Orbitrap HRMS)对强力五虎合剂的化学成分进行快速定性分析。方法采用Hypersil Acclaim aQ(2.1 mm×150 mm,1.9μm)色谱柱,以0.05%甲酸水(A)-甲醇(B)为流动相梯度洗... 目的基于超高效液相色谱-四极杆-静电场轨道阱高分辨质谱法(UPLC-Q-Orbitrap HRMS)对强力五虎合剂的化学成分进行快速定性分析。方法采用Hypersil Acclaim aQ(2.1 mm×150 mm,1.9μm)色谱柱,以0.05%甲酸水(A)-甲醇(B)为流动相梯度洗脱,流速0.3 mL/min,进样量2μL,柱温40℃。高分辨质谱采用电喷雾离子源(electrospray ion source,ESI),正、负离子切换模式扫描,扫描方式为全扫描/数据依赖二级扫描(Full MS/data-dependent secondary scan,Full MS/dd-MS^(2))。采集数据通过Compound Discoverer 3.0软件进行分析,根据化合物的精确相对分子质量、色谱保留时间,以及特征离子碎片信息,结合数据库(ChemSpider,mzCloud,mzVault)及相关文献和对照品信息比对鉴定强力五虎合剂的化学成分。结果从强力五虎合剂中共鉴定出102个成分,其中12个成分经与对照品比对后可准确鉴别。结论该方法可快速准确对强力五虎合剂的化学成分进行定性分析,阐明中药复方制剂的化学物质基础,为强力五虎合剂的质量控制提供技术支持。 展开更多
关键词 强力五虎合剂 超高效液相色谱-四极杆-静电场轨道阱高分辨质谱法 化学成分
在线阅读 下载PDF
Design method of high prestressed support for shallow-buried large-span caverns
14
作者 JIANG Bei WEI Hua-yong +3 位作者 WANG Qi WANG Ming-zi YIN Chen ZHANG Yan-bo 《Journal of Central South University》 2025年第3期1099-1116,共18页
The surrounding rock is prone to large-scale loosening and failure after the excavation of shallow large-span caverns because of the thin overlying strata and large cross-section span.The rational design of bolt suppo... The surrounding rock is prone to large-scale loosening and failure after the excavation of shallow large-span caverns because of the thin overlying strata and large cross-section span.The rational design of bolt support is very important to the safety control of surrounding rock as a common support means.The control mechanism and design method of bolt support for shallow-buried large-span caverns is carried out.The calculation method of bolt prestress and length based on arched failure and collapsed failure mode is established.The influence mechanism of different influencing factors on the bolt prestress and length is clarified.At the same time,the constant resistance energy-absorbing bolt with high strength and high toughness is developed,and the comparative test of mechanical properties is carried out.On this basis,the design method of high prestressed bolt support for shallow-buried large-span caverns is put forward,and the field test is carried out in Qingdao metro station in China.The monitoring results show that the maximum roof settlement is 6.8 mm after the new design method is adopted,and the effective control of the shallow-buried large-span caverns is realized.The research results can provide theoretical and technical support for the safety control of shallow-buried large-span caverns. 展开更多
关键词 Hoek-Brown strength criterion shallow-buried large-span caverns limit analysis upper bound method high prestress bolt support design method
在线阅读 下载PDF
Preparation of Si/NC/CL-20 Composite Explosives by Electrostatic Spraying Method and Its Performance Characterization
15
作者 DUAN Yi-long WANG Ling-xin +3 位作者 DONG Jun LI Xiu-long HE Xi JI Wei 《火炸药学报》 北大核心 2025年第5期424-429,I0001,共7页
To study the influence of silicon(Si)on 2,4,6,8,10,12-hexanitro-2,4,6,8,10,12-hexaazaisowurtzitane(CL-20),NC/CL-20 composite explosives and Si/NC/CL-20 composite explosives were prepared by the electrostatic spraying ... To study the influence of silicon(Si)on 2,4,6,8,10,12-hexanitro-2,4,6,8,10,12-hexaazaisowurtzitane(CL-20),NC/CL-20 composite explosives and Si/NC/CL-20 composite explosives were prepared by the electrostatic spraying method.The morphology,structure and thermal decomposition properties of the samples were analyzed using scanning electron microscopy(SEM),X-ray energy spectroscopy(EDS),infrared spectroscopy(FT-IR),and simultaneous thermal analyzer(TG-DSC).Additionally,the combustion process of the samples was tested using a high-speed camera.The results show that the addition of nano-Si contributes to the formation of composite explosives with regular morphology and smaller particle size.The Si/NC/CL-20 composite explosive has better and more uniform sphericity,with an average particle size of 73.4 nm,compared to the NC/CL-20 composite explosive.The Si/NC/CL-20 composite explosive which produced by the electrostatic spraying method,achieves physically uniform distribution of the components including NC,CL-20,Si.The addition of Si promotes the thermal decomposition of CL-20.In comparison to the NC/CL-20 composite explosive,the activation energy of the Si/NC/CL-20 composite explosive decreases by 16.78 kJ/mol,and the self-accelerated decomposition temperature and the critical temperature of thermal explosion decreases by 3.12 K and 2.61 K,respectively.Furthermore,Si/NC/CL-20 composite explosive has shorter ignition delay time and faster combustion rate compared to the NC/CL-20 composite explosive,which shows that Si can improve the combustion performance of CL-20. 展开更多
关键词 applied chemistry electrostatic spraying method SI Si/NC/CL-20 thermal decomposition performance combustion performance
在线阅读 下载PDF
基于UPLC-Q-Orbitrap-HRMS的地榆炒炭前后化学成分差异分析
16
作者 刘畅 周熙 +2 位作者 刘倩宝 吴惠勤 罗辉泰 《分析测试学报》 北大核心 2025年第11期2362-2368,共7页
采用超高效液相色谱-四极杆-静电场轨道阱高分辨质谱法(UPLC-Q-Orbitrap HRMS)分析地榆及其炮制品地榆炭的化学成分,并通过化学模式识别方法分析二者的差异成分。采用Waters BEH C18(100 mm×2.1 mm,1.7μm)色谱柱进行分离;以0.1%... 采用超高效液相色谱-四极杆-静电场轨道阱高分辨质谱法(UPLC-Q-Orbitrap HRMS)分析地榆及其炮制品地榆炭的化学成分,并通过化学模式识别方法分析二者的差异成分。采用Waters BEH C18(100 mm×2.1 mm,1.7μm)色谱柱进行分离;以0.1%甲酸水溶液-乙腈为流动相进行梯度洗脱,采用加热电喷雾离子源,正、负离子模式下采集数据。根据分子离子峰的精确质量数和二级碎片信息,结合文献及数据库,鉴定出地榆、地榆炭中共41个化学成分,其中酚类17个、黄酮类12个、三萜类9个及其他类化合物3个。应用SIMCA 14.1软件对各化合物的峰面积进行主成分分析和正交偏最小二乘判别分析,筛选地榆与地榆炭的差异成分。炒炭后,收敛止血活性成分没食子酸、地榆皂苷Ⅱ、委陵菜酸与熊果酸的含量升高,而葡萄糖没食子鞣苷、儿茶素、短叶苏木酚酸、鞣花酸及坡模酸的含量降低。地榆炭中的三萜和酚类化合物可能是其收敛止血功效增强的主要内在物质基础。该研究可为地榆炒炭炮制后止血作用增强的内在机制提供科学参考。 展开更多
关键词 地榆 UPLC-Q-Orbitrap-hrmS 化学成分 中药炮制 高分辨质谱 差异分析
在线阅读 下载PDF
A Fast Algorithm for Solving the Poisson Equations Based on the Discrete Cosine/Sine Transforms in the Finite Difference Method
17
作者 LI Congcong WANG Danxia +1 位作者 JIA Hongen ZHANG Chenhui 《应用数学》 北大核心 2025年第3期651-669,共19页
To enhance the computational efficiency of spatio-temporally discretized phase-field models,we present a high-speed solver specifically designed for the Poisson equations,a component frequently used in the numerical c... To enhance the computational efficiency of spatio-temporally discretized phase-field models,we present a high-speed solver specifically designed for the Poisson equations,a component frequently used in the numerical computation of such models.This efficient solver employs algorithms based on discrete cosine transformations(DCT)or discrete sine transformations(DST)and is not restricted by any spatio-temporal schemes.Our proposed methodology is appropriate for a variety of phase-field models and is especially efficient when combined with flow field systems.Meanwhile,this study has conducted an extensive numerical comparison and found that employing DCT and DST techniques not only yields results comparable to those obtained via the Multigrid(MG)method,a conventional approach used in the resolution of the Poisson equations,but also enhances computational efficiency by over 90%. 展开更多
关键词 Phase-field model Finite difference method Fast Poisson solver(DC-T/DST) Explicit invariant energy quadratization Unconditional energy stability
在线阅读 下载PDF
Size-dependent heat conduction of thermal cellular structures: A surface-enriched multiscale method
18
作者 Xiaofeng Xu Junfeng Li +2 位作者 Xuanhao Wu Ling Ling Li Li 《Defence Technology(防务技术)》 2025年第7期50-67,共18页
This paper examined how microstructure influences the homogenized thermal conductivity of cellular structures and revealed a surface-induced size-dependent effect.This effect is linked to the porous microstructural fe... This paper examined how microstructure influences the homogenized thermal conductivity of cellular structures and revealed a surface-induced size-dependent effect.This effect is linked to the porous microstructural features of cellular structures,which stems from the degree of porosity and the distri-bution of the pores.Unlike the phonon-driven surface effect at the nanoscale,the macro-scale surface mechanism in thermal cellular structures is found to be the microstructure-induced changes in the heat conduction path based on fully resolved 3D numerical simulations.The surface region is determined by the microstructure,characterized by the intrinsic length.With the coupling between extrinsic and intrinsic length scales under the surface mechanism,a surface-enriched multiscale method was devel-oped to accurately capture the complex size-dependent thermal conductivity.The principle of scale separation required by classical multiscale methods is not necessary to be satisfied by the proposed multiscale method.The significant potential of the surface-enriched multiscale method was demon-strated through simulations of the effective thermal conductivity of a thin-walled metamaterial struc-ture.The surface-enriched multiscale method offers higher accuracy compared with the classical multiscale method and superior efficiency over high-fidelity finite element methods. 展开更多
关键词 Thermal conductivity Surface-enriched multiscale method METAMATERIAL Surface effect Multi-scale modeling
在线阅读 下载PDF
A high output power 340 GHz balanced frequency doubler designed based on linear optimization method
19
作者 LIU Zhi-Cheng ZHOU Jing-Tao +5 位作者 MENG Jin WEI Hao-Miao YANG Cheng-Yue SU Yong-Bo JIN Zhi JIA Rui 《红外与毫米波学报》 北大核心 2025年第2期184-191,共8页
In this paper,a linear optimization method(LOM)for the design of terahertz circuits is presented,aimed at enhancing the simulation efficacy and reducing the time of the circuit design workflow.This method enables the ... In this paper,a linear optimization method(LOM)for the design of terahertz circuits is presented,aimed at enhancing the simulation efficacy and reducing the time of the circuit design workflow.This method enables the rapid determination of optimal embedding impedance for diodes across a specific bandwidth to achieve maximum efficiency through harmonic balance simulations.By optimizing the linear matching circuit with the optimal embedding impedance,the method effectively segregates the simulation of the linear segments from the nonlinear segments in the frequency multiplier circuit,substantially improving the speed of simulations.The design of on-chip linear matching circuits adopts a modular circuit design strategy,incorporating fixed load resistors to simplify the matching challenge.Utilizing this approach,a 340 GHz frequency doubler was developed and measured.The results demonstrate that,across a bandwidth of 330 GHz to 342 GHz,the efficiency of the doubler remains above 10%,with an input power ranging from 98 mW to 141mW and an output power exceeding 13 mW.Notably,at an input power of 141 mW,a peak output power of 21.8 mW was achieved at 334 GHz,corresponding to an efficiency of 15.8%. 展开更多
关键词 linear optimization method(LOM) three-dimensional electromagnetic model(3D-EM) Harmonic impedance optimization Schottky planar diode Terahertz frequency doubler
在线阅读 下载PDF
Modeling the electronic band-structure of strained long-wavelength Type-Ⅱsuperlattices using the scattering matrix method
20
作者 Abbas Haddadi Gail Brown Manijeh Razeghi 《红外与毫米波学报》 北大核心 2025年第3期346-351,共6页
This study introduces a comprehensive theoretical framework for accurately calculating the electronic band-structure of strained long-wavelength InAs/GaSb type-Ⅱsuperlattices.Utilizing an eight-band k·p Hamilto⁃... This study introduces a comprehensive theoretical framework for accurately calculating the electronic band-structure of strained long-wavelength InAs/GaSb type-Ⅱsuperlattices.Utilizing an eight-band k·p Hamilto⁃nian in conjunction with a scattering matrix method,the model effectively incorporates quantum confinement,strain effects,and interface states.This robust and numerically stable approach achieves exceptional agreement with experimental data,offering a reliable tool for analyzing and engineering the band structure of complex multi⁃layer systems. 展开更多
关键词 type-Ⅱsuperlattices long-wavelength infrared(LWIR) scattering matrix method electronic band-structure modeling InAs/GaSb heterostructures infrared photodetectors bandgap engineering
在线阅读 下载PDF
上一页 1 2 250 下一页 到第
使用帮助 返回顶部