Calcium production and the stellar evolution of first-generation stars remain fascinating mysteries in astrophysics.As one possible nucleosynthesis scenario,break-out from the hot carbon–nitrogen–oxygen(HCNO)cycle w...Calcium production and the stellar evolution of first-generation stars remain fascinating mysteries in astrophysics.As one possible nucleosynthesis scenario,break-out from the hot carbon–nitrogen–oxygen(HCNO)cycle was thought to be the source of the calcium observed in these oldest stars.However,according to the stellar modeling,a nearly tenfold increase in the thermonuclear rate ratio of the break-out ^(19)F(p,γ)^(20) Ne reaction with respect to the competing ^(19)F(p,α)^(16) O back-processing reaction is required to reproduce the observed calcium abundance.We performed a direct measurement of this break-out reaction at the China Jinping underground laboratory.The measurement was performed down to the low-energy limit of E_(c.m.)=186 keV in the center-of-mass frame.The key resonance was observed at 225.2 keV for the first time.At a temperature of approximately 0.1 GK,this new resonance enhanced the thermonuclear ^(19)F(p,γ)^(20) Ne rate by up to a factor of≈7.4,compared with the previously recommended NACRE rate.This is of particular interest to the study of the evolution of the first stars and implies a stronger breakdown in their“warm”CNO cycle through the ^(19)F(p,γ)^(20) Ne reaction than previously envisioned.This break-out resulted in the production of the calcium observed in the oldest stars,enhancing our understanding of the evolution of the first stars.展开更多
The advantage of the network laboratory is the better flexibility of lab experiments by allowing remote control from different locations at a freely chosen time. In engineering education, the work should not only be f...The advantage of the network laboratory is the better flexibility of lab experiments by allowing remote control from different locations at a freely chosen time. In engineering education, the work should not only be focused on the technical realization of virtual or remote access experiments, but also on the achievement of its pedagogical goals. In this paper, an interactive laboratory is introduced which is based on the online tutoring system, virtual and remote access experiments. It has been piloted in the Department of Electronic Science and Technology, HUST. Some pedagogical issues for electronic engineering laboratory design, the development of a multi-serverbased distributed architecture for the reduction of network latency and implementations of the function module are presented. Finally, the system is proved valid by an experiment.展开更多
Objective To analyze characteristics of high altitude pulmonary edema(HAPE)in Chinese patients.Methods We performed a retrospective study of 98 patients with HAPE.We reviewed the medical records and summarized the cli...Objective To analyze characteristics of high altitude pulmonary edema(HAPE)in Chinese patients.Methods We performed a retrospective study of 98 patients with HAPE.We reviewed the medical records and summarized the clinical,laboratory and imaging characteristics of these cases,and compared the results on admission with those determined before discharge.Results Forty-eight(49.0%)patients developed HAPE at the altitude of 2800 m to 3000 m.Ninty-five(96.9%)patients were man.Moist rales were audible from the both lungs,and moist rales over the right lung were clearer than those over the left lung in fourteen patients.The white blood cells[(12.83±5.55)versus(8.95±3.23)×109/L,P=0.001)]as well as neutrophil counts[(11.34±3.81)versus(7.49±2.83)×109/L,P=0.001)]were higher,whereas the counts of other subsets of white blood cells were lower on admission than those after recovery(all P<0.05).Serum levels of alkaline phosphatase(115.8±37.6 versus 85.7±32.4 mmol/L,P=0.020),cholinesterase(7226.2±1631.8 versus 6285.3±1693.3 mmol/L,P=0.040),creatinine(85.2±17.1 versus 75.1±12.8 mmol/L,P=0.021),uric acid(401.9±114.2 versus 326.0±154.3 mmol/L,P=0.041),and uric glucose(7.20±1.10 versus 5.51±1.11 mmol/L,P=0.001)were higher,but carbondioxide combining power(CO2CP,26.7±4.4 versus 28.9±4.5 mmol/L,P=0.042)and serous calcium(2.32±0.13 versus 2.41±0.10 mmol/L,P=0.006)were lower on admission.Arterial blood gas results showed hypoxemia and respiratory alkalosis on admission.Conclusions In the present research,men were more susceptible to HAPE than women,and in the process of HAPE,the lesions of the right lung were more serious than those of the left lung.Some indicators of routine blood test and blood biochemistry of HAPE patients changed.展开更多
Intrinsic radiation of materials is one of the major backgrounds for many rare-event search experiments.Thus,the production of pure materials in an underground laboratory is a promising approach for eliminating cosmog...Intrinsic radiation of materials is one of the major backgrounds for many rare-event search experiments.Thus,the production of pure materials in an underground laboratory is a promising approach for eliminating cosmogenic radionuclides.In this paper,we demonstrate a procedure to evaluate the yields of cosmogenic radionuclides in copper and germanium in the second phase of the China Jinping Underground Laboratory.Our results show that for copper and germanium materials,the largest cosmogenic background comes from 3 H and57,58,60Co,and 3 H and 68Ge,respectively,which all have yields on the order of 10-7 kg-1 day-1.The corresponding radioactivities after 90 days pf exposure underground are estimated to be lower than 10-6μBq kg-1.展开更多
This paper tries to build a multi-functional downhole nuclear magnetic resonance (NMR) fluid analysis laboratory that can evaluate fluid information in real time at reservoir conditions at a depth of several thousan...This paper tries to build a multi-functional downhole nuclear magnetic resonance (NMR) fluid analysis laboratory that can evaluate fluid information in real time at reservoir conditions at a depth of several thousand meters. The aim is to monitor the pollution of the formation fluids and quantitatively evaluate NMR characteristics of the fluids. It focuses on the design of the structure and parameters of a sensor with zero stray fields. Two separate coils are designed to measure NMR characteristics of flowing or static fluids. A method is proposed to use the Bloch equation, to guide the optimization of the NMR sensor. Finally, the measured results confirm that the design is reasonable. There is a homogeneous static field (perpendicular to the axial direction) in the center of the sensor, and there are no stray external fields. The novel design of pre-polarization magnet improves the signal to noise ratio, while shortening the sensor length.展开更多
Steel mesh is used as a passive skin confinement medium to supplement the active support provided by rock bolts for roof and rib control in underground coal mines. Thin spray-on liners(TSL) are believed to have the po...Steel mesh is used as a passive skin confinement medium to supplement the active support provided by rock bolts for roof and rib control in underground coal mines. Thin spray-on liners(TSL) are believed to have the potential to take the place of steel mesh as the skin confinement medium in underground mines.To confirm this belief, large scale laboratory experiments were conducted to compare the behaviour of welded steel mesh and a TSL, when used in conjunction with rock bolts, in reinforcing strata with weak bedding planes and strata prone to guttering, two common rock conditions which exist in coal mines. It was found that while the peak load taken by the simulated rock mass with weak bedding planes acting as the control sample(no skin confinement) was 2494 kN, the corresponding value of the sample with 5 mm thick TSL reinforcement reached 2856 kN. The peak load of the steel mesh reinforced sample was only2321 kN, but this was attributed to the fact that one of the rock bolts broke during the test. The TSL reinforced sample had a similar post-yield behaviour as the steel mesh reinforced one. The results of the large scale guttering test indicated that a TSL is better than steel mesh in restricting rock movement and thus inhibiting the formation of gutters in the roof.展开更多
The transition to a non-emitting energy mix for power generation will take decades. This transition will need to be sustainable, e.g.economically affordable. Fossil fuels which are abundant have an important role to p...The transition to a non-emitting energy mix for power generation will take decades. This transition will need to be sustainable, e.g.economically affordable. Fossil fuels which are abundant have an important role to play in this respect, provided that Carbon Capture and Storage(CCS) is progressively implemented. CCS is the only way to reduce emissions from energy intensive industries.Thus, the need for upgraded and new CCS research facilities is widely recognised among stakeholders across Europe, as emphasised by the Zero Emissions Platform(ZEP) [1] and the European Energy Research Alliance on CCS(EERA-CCS) [2].The European Carbon Dioxide Capture and Storage Laboratory Infrastructure, ECCSEL, provides funders, operators and researchers with significant benefits by offering access to world-class research facilities that, in many cases, are unlikely for a single nation to support in isolation.This implies creation of synergy and the avoidance of duplication as well as streamlining of funding for research facilities.ECCSEL offers open access to its advanced laboratories for talented scientists and visiting researchers to conduct cutting-edge research.In the planning of ECCSEL, gap analyses were performed and CCS technologies have been reviewed to underpin and envisage the future experimental setup; 1) Making use of readily available facilities, 2) Modifying existing facilities, and 3) Planning and building entirely new advanced facilities.The investments required for the first ten years(2015-2025) are expected to be in the range of €80-120 miilion. These investments show the current level of ambition, as proposed during the preparatory phase(2011-2014).Entering the implementation phase in 2015, 9 European countries signed Letter of Intent(LoI) to join a ECCSEL legal entity: France, United Kingdom, Netherlands, Italy, Spain, Poland, Greece, Norway and Switzerland(active observer). As the EU ERIC-regulation [3] would offer the most suitable legal framework for ECCSEL, the host country, Norway, will apply for establishing ERIC as the ECCSEL Research Infrastructure(RI)legal entity in 2017. Until the ECCSEL ERIC is approved by the European Commission(probably by summer 2017), an interim MoU agreement for the implementation phase of ECCSEL RI has been signed by 13 research institutions and universities representing the 9 countries. A consortium of these partners were granted 3 million EURO from Horizon 2020 to boost implementation of ECCSEL from September 2015 and two years onwards.?2016, Institute of Process Engineering, Chinese Academy of Sciences. Publishing services by Elsevier B.V. on behalf of KeAi Communications Co., Ltd. This is an open access article under the CC BY-NC-ND license(http://creativecommons.org/licenses/by-nc-nd/4.0/).展开更多
Chinese scientists have been actively engaged in biotechnology research since the mid-2Oth century.However,biotechnology education,especially biomedical laboratory technology education,is relatively scarce in China.Mo...Chinese scientists have been actively engaged in biotechnology research since the mid-2Oth century.However,biotechnology education,especially biomedical laboratory technology education,is relatively scarce in China.More and more cutting-edge equipment and techniques have been introduced into biomedical laboratories in China,but there is a lack of high-quality techni&ans to apply these advancements to scientific research.In addition,the traditional education and apprenticeship systems have been demonstrated little progress.To address this gap,West China Hospital of Sichuan University established a 2-year educational program for laboratory technology in 2006 based on the residency training program.The project integrates scientific methods into the research laboratory technician training in relevant disciplines,and has developed a systematic,scientific,and effective standardized training system to cultivate high-level and stable experimental technician team for the need of advanced laboratories,which has been demonstrated gready improve the efficiency of biomedical researchers and laboratory facilities.In this article,we introduce the practical experience in establishment and development of a standardized training system for biomedical laboratory technicians to ensure the sustainable development of medical researches.展开更多
Phenomenon: Nowadays, with rapidly developing in medical laboratory science(MLS), new concepts, knowledge and technologies are constantly emerging, which requires medical students to continuously learn to grasp the ne...Phenomenon: Nowadays, with rapidly developing in medical laboratory science(MLS), new concepts, knowledge and technologies are constantly emerging, which requires medical students to continuously learn to grasp the new development trend and the latest research progress. To enable the students to learn and make use of scientific knowledge better, the Special English Curriculum for MLS has been set up, which is very important to non-English-speaking students. However, there are many problems in the course of teaching, so the improved teaching quality of the curriculum is in demand. Approach: In this paper these problems are described and the corresponding advices are proposed from the perspectives of staff room, teachers and students, which are supposed to develop the curriculum for education of the medical laboratory scientists. Findings: To improve the teaching quality of the Special English Curriculum for MLS, the textbook should be appropriately selected or compiled, the novel teaching methods can be applied, and the modern multimedia teaching materials can be adopted.The teachers of the curriculum should be proficient in professional knowledge, English as well as the systematic and scientific teaching methods. The students need to have the courage and determination to overcome the difficulties when they learn the curriculum, and the students who have not did well in their lessons should learn to study by themselves. Insights: The Special English Curriculum for MLS is very important to non-English-speaking students and is kind of difficult for them, the staff room, teachers and students should adjust themselves to teach and learn the curriculum better.展开更多
Dalian National Laboratory for Clean Energy (DNL), based mainly in Dalian Institute of Chemical Physics (DICP), Chinese Academy of Sciences (CAS), is looking for outstanding candidates for DNL director and direc...Dalian National Laboratory for Clean Energy (DNL), based mainly in Dalian Institute of Chemical Physics (DICP), Chinese Academy of Sciences (CAS), is looking for outstanding candidates for DNL director and directors for its nine research divisions: optimized utilization of fossil energy, low carbon catalysis and engineering, energy saving & energy environment, fuel cell & energy storage, hydrogen energy, biomass energy, solar energy, maritime renewable energy, basic & strategic studies on energy, and service center for energy researches. More details about DICP can be found at http://www.dicp.ac.cn/.展开更多
In deep hard rock excavation, stress plays a pivotal role in inducing stress-controlled failure. While the impact of excavation-induced stress disturbance on rock failure and tunnel stability has undergone comprehensi...In deep hard rock excavation, stress plays a pivotal role in inducing stress-controlled failure. While the impact of excavation-induced stress disturbance on rock failure and tunnel stability has undergone comprehensive examination through laboratory tests and numerical simulations, its validation through insitu stress tests remains unexplored. This study analyzes the three-dimensional stress changes in the surrounding rock at various depths, monitored during the excavation of B2 Lab in China Jinping Underground Laboratory Phase Ⅱ(CJPL-Ⅱ). The investigation delves into the three-dimensional stress variation characteristics in deep hard rock, encompassing stress components and principal stress. The results indicate changes in both the magnitude and direction of the principal stress during tunnel excavation. To quantitatively describe the degree of stress disturbance, a series of stress evaluation indexes are established based on the distances between stress tensors, including the stress disturbance index(SDI), the principal stress magnitude disturbance index(SDIm), and the principal stress direction disturbance index(SDId). The SDI indicates the greatest stress disturbance in the surrounding rock is 4.5 m from the tunnel wall in B2 Lab. SDIm shows that the principal stress magnitude disturbance peaks at2.5 m from the tunnel wall. SDId reveals that the largest change in principal stress direction does not necessarily occur near the tunnel wall but at a specific depth from it. The established relationship between SDI and the depth of the excavation damaged zone(EDZ) can serve as a criterion for determining the depth of the EDZ in deep hard rock engineering. Additionally, it provides a reference for future construction and support considerations.展开更多
Nuclear astrophysics is a rapidly developing interdisciplinary feld of research that has received extensive attention from the scientifc community since the midtwentieth century.Broadly,it uses the laws of extremely s...Nuclear astrophysics is a rapidly developing interdisciplinary feld of research that has received extensive attention from the scientifc community since the midtwentieth century.Broadly,it uses the laws of extremely small atomic nuclei to explain the evolution of the universe.Owing to the complexity of nucleosynthesis processes and our limited understanding of nuclear physics in astrophysical environments,several critical astrophysical problems remain unsolved.To achieve a better understanding of astrophysics,it is necessary to measure the cross sections of key nuclear reactions with the precision required by astrophysical models.Direct measurement of nuclear reaction cross sections is an important method of investigating how nuclear reactions infuence stellar evolution.Given the challenges involved in measuring the extremely low crosssections of nuclear reactions in the Gamow peak and preparing radioactive targets,indirect methods,such as the transfer reaction,coulomb dissociation,and surrogate ratio methods,have been developed over the past several decades.These are powerful tools in the investigation of,for example,neutron-capture(n,r)reactions with short-lived radioactive isotopes.However,direct measurement is still preferable,such as in the case of reactions involving light and stable nuclei.As an essential part of stellar evolution,these low-energy stable nuclear reactions have been of particular interest in recent years.To overcome the diffculties in measurements near or deeply within the Gamow window,the combination of an underground laboratory and high-exposure accelerator/detector complex is currently the optimal solution.Therefore,underground experiments have emerged as a new and promising direction of research.In addition,to better simulate the stellar environment in the laboratory,research on nuclear physics under laser-driven plasma conditions has gradually become a frontier hotspot.In recent years,the CIAE team conducted a series of distinctive nuclear astrophysics studies,relying on the Jinping Underground Nuclear Astrophysics platform and accelerators in Earth’s surface laboratories,including the Beijing Radioactive Ion beam Facility,as well as other scientifc platforms at home and abroad.This research covered nuclear theories,numerical models,direct measurements,indirect measurements,and other novel approaches,achieving great interdisciplinary research results,with high-level academic publications and signifcant international impacts.This article reviews the above research and predicts future developments.展开更多
Laboratory experiments,numerical simulations and fracturing technology were combined to address the problems in shale oil recovery by CO_(2)injection.The laboratory experiments were conducted to investigate the displa...Laboratory experiments,numerical simulations and fracturing technology were combined to address the problems in shale oil recovery by CO_(2)injection.The laboratory experiments were conducted to investigate the displacement mechanisms of shale oil extraction by CO_(2)injection,and the influences of CO_(2)pre-pad on shale mechanical properties.Numerical simulations were performed about influences of CO_(2)pre-pad fracturing and puff-n-huff for energy replenishment on the recovery efficiency.The findings obtained were applied to the field tests of CO_(2)pre-pad fracturing and single well puff-n-huff.The results show that the efficiency of CO_(2)puff-n-huff is affected by micro-and nano-scale effect,kerogen,adsorbed oil and so on,and a longer soaking time in a reasonable range leads to a higher exploitation degree of shale oil.In the"injection+soaking"stage,the exploitation degree of heavy hydrocarbons is enhanced by CO_(2)through its effects of solubility-diffusion and mass-transfer.In the"huff"stage,crude oil in large pores is displaced by CO_(2)to surrounding larger pores or bedding fractures and finally flows to the production well.The injection of CO_(2)pre-pad is conducive to keeping the rock brittle and reducing the fracture breakdown pressure,and the CO_(2)is liable to filter along the bedding surface,thereby creating a more complex fracture.Increasing the volume of CO_(2)pre-pad can improve the energizing effect,and enhance the replenishment of formation energy.Moreover,the oil recovery is more enhanced by CO_(2)huff-n-puff with the lower shale matrix permeability,the lower formation pressure,and the larger heavy hydrocarbon content.The field tests demonstrate a good performance with the pressure maintained well after CO_(2)pre-pad fracturing,the formation energy replenished effectively after CO_(2)huff-n-puff in a single well,and the well productivity improved.展开更多
The SSRF phase-Ⅱ beamline project was launched in 2016. Its major goal was to establish a systematic state-of-the-art experimental facility for third-generation synchrotron radiation to solve problems in cutting-edge...The SSRF phase-Ⅱ beamline project was launched in 2016. Its major goal was to establish a systematic state-of-the-art experimental facility for third-generation synchrotron radiation to solve problems in cutting-edge science and technology.Currently, the construction is fully completed. All 16 newly built beamlines with nearly 60 experimental methods passed acceptance testing by the Chinese Academy of Sciences and are in operation.展开更多
The deep earth,deep sea,and deep space are the main parts of the national“three deep”strategy,which is in the forefront of the strategic deployment clearly defined in China’s 14th Five-Year Plan(2021-2025)and the L...The deep earth,deep sea,and deep space are the main parts of the national“three deep”strategy,which is in the forefront of the strategic deployment clearly defined in China’s 14th Five-Year Plan(2021-2025)and the Long-Range Objectives Through the Year 2035.It is important to reveal the evolutionary process and mechanism of deep tectonics to understand the earth’s past,present and future.The academic con-notation of Geology in Time has been given for the first time,which refers to the multi-field evolution response process of geological bodies at different time and spatial scales caused by geological processes inside and outside the Earth.Based on the deep in situ detection space and the unique geological envi-ronment of China Jinping Underground Laboratory,the scientific issue of the correlation mechanism and law between deep internal time-varying and shallow geological response is given attention.Innovative research and frontier exploration on deep underground in situ geo-information detection experiments for Geology in Time are designed to be carried out,which will have the potential to explore the driving force of Geology in Time,reveal essential laws of deep earth science,and explore innovative technologies in deep underground engineering.展开更多
Complexities in mechanical behaviours of rock masses mainly stem from inherent discontinuities,which calls for advanced bolt-grouting techniques for stability enhancement.Understanding the mechanical properties of bol...Complexities in mechanical behaviours of rock masses mainly stem from inherent discontinuities,which calls for advanced bolt-grouting techniques for stability enhancement.Understanding the mechanical properties of bolt-grouted fractured rock mass(BGFR)and developing accurate prediction methods are crucial to optimize the BGFR support strategies.This paper establishes a new elastoplastic(E-P)model based on the orthotropic and the Mohr-Coulomb(M-C)plastic-yielding criteria.The elastic parameters of the model were derived through a meso-mechanical analysis of composite materials mechanics(CMM).Laboratory BGFR specimens were prepared and uniaxial compression test and variable-angle shear test considering different bolt arrangements were carried out to obtain the mechanical parameters of the specimens.Results showed that the anisotropy of BGFR mainly depends on the relative volume content of each component material in a certain direction.Moreover,the mechanical parameters deduced from the theory of composite materials which consider the short fibre effect are shown to be in good agreement with those determined by laboratory experiments,and the variation rules maintained good consistency.Last,a case study of a real tunnel project is provided to highlight the effectiveness,validity and robustness of the developed E-P model in prediction of stresses and deformations.展开更多
In astrophysics, the boundary conditions for plasma phenomena are provided by nature and the astronomer faces the problem of understanding them from a variety of observations [Hester J J et al 1996 Astrophys. J. 456 2...In astrophysics, the boundary conditions for plasma phenomena are provided by nature and the astronomer faces the problem of understanding them from a variety of observations [Hester J J et al 1996 Astrophys. J. 456 225], on the other hand, in laboratory plasma experiments the electromagnetic boundary conditions become a major problem in the set-up of the machine that produces the plasma, an issue that has to be investigated step by step and to be modified and adapted with great patience, in particular in the case of an innovative plasma confinement experiment. The PROTO-SPHERA machine [Alladio F et al 2006 Nucl. Fusion 46 S613] is a magnetic confinement experiment, that emulates in the laboratory the jet + torus plasma configurations often observed in astrophysics: an inner magnetized jet of plasma centered on the(approximate) axis of symmetry and surrounded by a magnetized plasma torus orthogonal to this jet. The PROTO-SPHERA plasma is simply connected, i.e., no metal current conducting rod is linked to the plasma torus, while instead it is the inner magnetized plasma jet(in the following always called the plasma centerpost) that is linked to the torus. It is mandatory that no spurious plasma current path modifies the optimal shape of the plasma centerpost. Moreover, as the plasma torus is produced and sustained, in absence of any applied inductive electric field, by the inner plasma centerpost through magnetic reconnections [Taylor J B and Turner M F 1989 Nucl.Fusion 29 219], it is required as well that spurious current paths do not surround the torus on its outboard, in order not to lower the efficiency of the magnetic reconnections that maintain the plasma torus at the expense of the plasma centerpost. Boundary conditions have been corrected,up to the point that the first sustainment in steady state has been achieved for the combined plasma.展开更多
Observing nuclear neutrinoless double beta (0vββ) decay would be a revolutionary result in particle physics.Observing such a decay would prove that the neutrinos are their own antiparticles,help to study the absolut...Observing nuclear neutrinoless double beta (0vββ) decay would be a revolutionary result in particle physics.Observing such a decay would prove that the neutrinos are their own antiparticles,help to study the absolute mass of neutrinos,explore the origin of their mass,and may explain the matter-antimatter asymmetry in our universe by lepton number violation.We propose developing a time projection chamber (TPC) using high-pressure ^(82)SeF_(6) gas and Topmetal silicon sensors for readout in the China Jinping Underground Laboratory (CJPL) to search for neutrinoless double beta decay of82Se,called the NvDEx experiment.Besides being located at CJPL with the world’s thickest rock shielding,NvDEx combines the advantages of the high Qββ(2.996 MeV) of82Se and the TPC’s ability to distinguish signal and background events using their different topological characteristics.This makes NvDEx unique,with great potential for low-background and high-sensitivity 0 vββsearches.NvDEx-100,a NvDEx experiment phase with 100 kg of SeF_(6)gas,is being built,with plans to complete installation at CJPL by 2025.This report introduces 0 vββ physics,the NvDEx concept and its advantages,and the schematic design of NvDEx-100,its subsystems,and background and sensitivity estimation.展开更多
In 2024,the Chinese Meridian Project(CMP)completed its construction,deploying 282 instruments across 31 stations.This achievement not only provides a robust foundation but also serves as a reference template for the I...In 2024,the Chinese Meridian Project(CMP)completed its construction,deploying 282 instruments across 31 stations.This achievement not only provides a robust foundation but also serves as a reference template for the International Meridian Circle Program(IMCP).The IMCP aims to integrate and establish a comprehensive network of ground-based monitoring stations designed to track the propagation of space weather events from the Sun to Earth.Additionally,it monitors various disturbances generated within the Earth system that impact geospace.Over the past two years,significant progress has been made on the IMCP.In particular,the second phase of construction for the China-Brazil Joint Laboratory for Space Weather has been completed,and the North Pole and Southeast Asia networks are under active construction.The 2024 IMCP joint observation campaign was successfully conducted.To facilitate these developments,the scientific program committee of IMCP was established,following the success of 2023 IMCP workshop and the space weather school,which was co-hosted with the Asia-Pacific Space Cooperation Organization(APSCO)and sponsored by Chinese Academy of Sciences(CAS)and Scientific Committee on Solar-Terrestrial Physics(SCOSTEP).Preparations are now underway for the 2024 workshop in collaboration with the National Institute for Space Research(INPE)in Brazil.展开更多
基金supported by the National Natural Science Foundation of China(Nos.12075027,1232509,11961141004,and 12175152)the National Science Foundation(Nos.Phys-2011890 and Phy-1430152)。
文摘Calcium production and the stellar evolution of first-generation stars remain fascinating mysteries in astrophysics.As one possible nucleosynthesis scenario,break-out from the hot carbon–nitrogen–oxygen(HCNO)cycle was thought to be the source of the calcium observed in these oldest stars.However,according to the stellar modeling,a nearly tenfold increase in the thermonuclear rate ratio of the break-out ^(19)F(p,γ)^(20) Ne reaction with respect to the competing ^(19)F(p,α)^(16) O back-processing reaction is required to reproduce the observed calcium abundance.We performed a direct measurement of this break-out reaction at the China Jinping underground laboratory.The measurement was performed down to the low-energy limit of E_(c.m.)=186 keV in the center-of-mass frame.The key resonance was observed at 225.2 keV for the first time.At a temperature of approximately 0.1 GK,this new resonance enhanced the thermonuclear ^(19)F(p,γ)^(20) Ne rate by up to a factor of≈7.4,compared with the previously recommended NACRE rate.This is of particular interest to the study of the evolution of the first stars and implies a stronger breakdown in their“warm”CNO cycle through the ^(19)F(p,γ)^(20) Ne reaction than previously envisioned.This break-out resulted in the production of the calcium observed in the oldest stars,enhancing our understanding of the evolution of the first stars.
基金This was work supported by the Program for New Century Excellent Talents inUniversity under Grand No. NCET-04-0702.
文摘The advantage of the network laboratory is the better flexibility of lab experiments by allowing remote control from different locations at a freely chosen time. In engineering education, the work should not only be focused on the technical realization of virtual or remote access experiments, but also on the achievement of its pedagogical goals. In this paper, an interactive laboratory is introduced which is based on the online tutoring system, virtual and remote access experiments. It has been piloted in the Department of Electronic Science and Technology, HUST. Some pedagogical issues for electronic engineering laboratory design, the development of a multi-serverbased distributed architecture for the reduction of network latency and implementations of the function module are presented. Finally, the system is proved valid by an experiment.
基金Supported by the National Science and Technology Major Projects for Major New Drugs Innovation and Development [2014ZX09J14102-02A(2014.1-2016.12)]
文摘Objective To analyze characteristics of high altitude pulmonary edema(HAPE)in Chinese patients.Methods We performed a retrospective study of 98 patients with HAPE.We reviewed the medical records and summarized the clinical,laboratory and imaging characteristics of these cases,and compared the results on admission with those determined before discharge.Results Forty-eight(49.0%)patients developed HAPE at the altitude of 2800 m to 3000 m.Ninty-five(96.9%)patients were man.Moist rales were audible from the both lungs,and moist rales over the right lung were clearer than those over the left lung in fourteen patients.The white blood cells[(12.83±5.55)versus(8.95±3.23)×109/L,P=0.001)]as well as neutrophil counts[(11.34±3.81)versus(7.49±2.83)×109/L,P=0.001)]were higher,whereas the counts of other subsets of white blood cells were lower on admission than those after recovery(all P<0.05).Serum levels of alkaline phosphatase(115.8±37.6 versus 85.7±32.4 mmol/L,P=0.020),cholinesterase(7226.2±1631.8 versus 6285.3±1693.3 mmol/L,P=0.040),creatinine(85.2±17.1 versus 75.1±12.8 mmol/L,P=0.021),uric acid(401.9±114.2 versus 326.0±154.3 mmol/L,P=0.041),and uric glucose(7.20±1.10 versus 5.51±1.11 mmol/L,P=0.001)were higher,but carbondioxide combining power(CO2CP,26.7±4.4 versus 28.9±4.5 mmol/L,P=0.042)and serous calcium(2.32±0.13 versus 2.41±0.10 mmol/L,P=0.006)were lower on admission.Arterial blood gas results showed hypoxemia and respiratory alkalosis on admission.Conclusions In the present research,men were more susceptible to HAPE than women,and in the process of HAPE,the lesions of the right lung were more serious than those of the left lung.Some indicators of routine blood test and blood biochemistry of HAPE patients changed.
基金supported by the National Natural Science Foundation of China(No.U1865205).
文摘Intrinsic radiation of materials is one of the major backgrounds for many rare-event search experiments.Thus,the production of pure materials in an underground laboratory is a promising approach for eliminating cosmogenic radionuclides.In this paper,we demonstrate a procedure to evaluate the yields of cosmogenic radionuclides in copper and germanium in the second phase of the China Jinping Underground Laboratory.Our results show that for copper and germanium materials,the largest cosmogenic background comes from 3 H and57,58,60Co,and 3 H and 68Ge,respectively,which all have yields on the order of 10-7 kg-1 day-1.The corresponding radioactivities after 90 days pf exposure underground are estimated to be lower than 10-6μBq kg-1.
基金Financial support from the National Science Foundation of China (Grant No. 41074102)the China International Science and Technology Cooperation (Grant No.2009DFA61030)
文摘This paper tries to build a multi-functional downhole nuclear magnetic resonance (NMR) fluid analysis laboratory that can evaluate fluid information in real time at reservoir conditions at a depth of several thousand meters. The aim is to monitor the pollution of the formation fluids and quantitatively evaluate NMR characteristics of the fluids. It focuses on the design of the structure and parameters of a sensor with zero stray fields. Two separate coils are designed to measure NMR characteristics of flowing or static fluids. A method is proposed to use the Bloch equation, to guide the optimization of the NMR sensor. Finally, the measured results confirm that the design is reasonable. There is a homogeneous static field (perpendicular to the axial direction) in the center of the sensor, and there are no stray external fields. The novel design of pre-polarization magnet improves the signal to noise ratio, while shortening the sensor length.
文摘Steel mesh is used as a passive skin confinement medium to supplement the active support provided by rock bolts for roof and rib control in underground coal mines. Thin spray-on liners(TSL) are believed to have the potential to take the place of steel mesh as the skin confinement medium in underground mines.To confirm this belief, large scale laboratory experiments were conducted to compare the behaviour of welded steel mesh and a TSL, when used in conjunction with rock bolts, in reinforcing strata with weak bedding planes and strata prone to guttering, two common rock conditions which exist in coal mines. It was found that while the peak load taken by the simulated rock mass with weak bedding planes acting as the control sample(no skin confinement) was 2494 kN, the corresponding value of the sample with 5 mm thick TSL reinforcement reached 2856 kN. The peak load of the steel mesh reinforced sample was only2321 kN, but this was attributed to the fact that one of the rock bolts broke during the test. The TSL reinforced sample had a similar post-yield behaviour as the steel mesh reinforced one. The results of the large scale guttering test indicated that a TSL is better than steel mesh in restricting rock movement and thus inhibiting the formation of gutters in the roof.
文摘The transition to a non-emitting energy mix for power generation will take decades. This transition will need to be sustainable, e.g.economically affordable. Fossil fuels which are abundant have an important role to play in this respect, provided that Carbon Capture and Storage(CCS) is progressively implemented. CCS is the only way to reduce emissions from energy intensive industries.Thus, the need for upgraded and new CCS research facilities is widely recognised among stakeholders across Europe, as emphasised by the Zero Emissions Platform(ZEP) [1] and the European Energy Research Alliance on CCS(EERA-CCS) [2].The European Carbon Dioxide Capture and Storage Laboratory Infrastructure, ECCSEL, provides funders, operators and researchers with significant benefits by offering access to world-class research facilities that, in many cases, are unlikely for a single nation to support in isolation.This implies creation of synergy and the avoidance of duplication as well as streamlining of funding for research facilities.ECCSEL offers open access to its advanced laboratories for talented scientists and visiting researchers to conduct cutting-edge research.In the planning of ECCSEL, gap analyses were performed and CCS technologies have been reviewed to underpin and envisage the future experimental setup; 1) Making use of readily available facilities, 2) Modifying existing facilities, and 3) Planning and building entirely new advanced facilities.The investments required for the first ten years(2015-2025) are expected to be in the range of €80-120 miilion. These investments show the current level of ambition, as proposed during the preparatory phase(2011-2014).Entering the implementation phase in 2015, 9 European countries signed Letter of Intent(LoI) to join a ECCSEL legal entity: France, United Kingdom, Netherlands, Italy, Spain, Poland, Greece, Norway and Switzerland(active observer). As the EU ERIC-regulation [3] would offer the most suitable legal framework for ECCSEL, the host country, Norway, will apply for establishing ERIC as the ECCSEL Research Infrastructure(RI)legal entity in 2017. Until the ECCSEL ERIC is approved by the European Commission(probably by summer 2017), an interim MoU agreement for the implementation phase of ECCSEL RI has been signed by 13 research institutions and universities representing the 9 countries. A consortium of these partners were granted 3 million EURO from Horizon 2020 to boost implementation of ECCSEL from September 2015 and two years onwards.?2016, Institute of Process Engineering, Chinese Academy of Sciences. Publishing services by Elsevier B.V. on behalf of KeAi Communications Co., Ltd. This is an open access article under the CC BY-NC-ND license(http://creativecommons.org/licenses/by-nc-nd/4.0/).
文摘Chinese scientists have been actively engaged in biotechnology research since the mid-2Oth century.However,biotechnology education,especially biomedical laboratory technology education,is relatively scarce in China.More and more cutting-edge equipment and techniques have been introduced into biomedical laboratories in China,but there is a lack of high-quality techni&ans to apply these advancements to scientific research.In addition,the traditional education and apprenticeship systems have been demonstrated little progress.To address this gap,West China Hospital of Sichuan University established a 2-year educational program for laboratory technology in 2006 based on the residency training program.The project integrates scientific methods into the research laboratory technician training in relevant disciplines,and has developed a systematic,scientific,and effective standardized training system to cultivate high-level and stable experimental technician team for the need of advanced laboratories,which has been demonstrated gready improve the efficiency of biomedical researchers and laboratory facilities.In this article,we introduce the practical experience in establishment and development of a standardized training system for biomedical laboratory technicians to ensure the sustainable development of medical researches.
文摘Phenomenon: Nowadays, with rapidly developing in medical laboratory science(MLS), new concepts, knowledge and technologies are constantly emerging, which requires medical students to continuously learn to grasp the new development trend and the latest research progress. To enable the students to learn and make use of scientific knowledge better, the Special English Curriculum for MLS has been set up, which is very important to non-English-speaking students. However, there are many problems in the course of teaching, so the improved teaching quality of the curriculum is in demand. Approach: In this paper these problems are described and the corresponding advices are proposed from the perspectives of staff room, teachers and students, which are supposed to develop the curriculum for education of the medical laboratory scientists. Findings: To improve the teaching quality of the Special English Curriculum for MLS, the textbook should be appropriately selected or compiled, the novel teaching methods can be applied, and the modern multimedia teaching materials can be adopted.The teachers of the curriculum should be proficient in professional knowledge, English as well as the systematic and scientific teaching methods. The students need to have the courage and determination to overcome the difficulties when they learn the curriculum, and the students who have not did well in their lessons should learn to study by themselves. Insights: The Special English Curriculum for MLS is very important to non-English-speaking students and is kind of difficult for them, the staff room, teachers and students should adjust themselves to teach and learn the curriculum better.
文摘Dalian National Laboratory for Clean Energy (DNL), based mainly in Dalian Institute of Chemical Physics (DICP), Chinese Academy of Sciences (CAS), is looking for outstanding candidates for DNL director and directors for its nine research divisions: optimized utilization of fossil energy, low carbon catalysis and engineering, energy saving & energy environment, fuel cell & energy storage, hydrogen energy, biomass energy, solar energy, maritime renewable energy, basic & strategic studies on energy, and service center for energy researches. More details about DICP can be found at http://www.dicp.ac.cn/.
基金financial support for this work from the National Natural Science Foundation of China(Nos.42202320 and 42102266)the Open Project of Engineering Research Center of Phosphorus Resources Development and Utilization of Ministry of Education(No.LKF201901).
文摘In deep hard rock excavation, stress plays a pivotal role in inducing stress-controlled failure. While the impact of excavation-induced stress disturbance on rock failure and tunnel stability has undergone comprehensive examination through laboratory tests and numerical simulations, its validation through insitu stress tests remains unexplored. This study analyzes the three-dimensional stress changes in the surrounding rock at various depths, monitored during the excavation of B2 Lab in China Jinping Underground Laboratory Phase Ⅱ(CJPL-Ⅱ). The investigation delves into the three-dimensional stress variation characteristics in deep hard rock, encompassing stress components and principal stress. The results indicate changes in both the magnitude and direction of the principal stress during tunnel excavation. To quantitatively describe the degree of stress disturbance, a series of stress evaluation indexes are established based on the distances between stress tensors, including the stress disturbance index(SDI), the principal stress magnitude disturbance index(SDIm), and the principal stress direction disturbance index(SDId). The SDI indicates the greatest stress disturbance in the surrounding rock is 4.5 m from the tunnel wall in B2 Lab. SDIm shows that the principal stress magnitude disturbance peaks at2.5 m from the tunnel wall. SDId reveals that the largest change in principal stress direction does not necessarily occur near the tunnel wall but at a specific depth from it. The established relationship between SDI and the depth of the excavation damaged zone(EDZ) can serve as a criterion for determining the depth of the EDZ in deep hard rock engineering. Additionally, it provides a reference for future construction and support considerations.
基金National Natural Science Foundation of China(Nos.12435010)National Key R&D Program of China(No.2022YFA1602301)。
文摘Nuclear astrophysics is a rapidly developing interdisciplinary feld of research that has received extensive attention from the scientifc community since the midtwentieth century.Broadly,it uses the laws of extremely small atomic nuclei to explain the evolution of the universe.Owing to the complexity of nucleosynthesis processes and our limited understanding of nuclear physics in astrophysical environments,several critical astrophysical problems remain unsolved.To achieve a better understanding of astrophysics,it is necessary to measure the cross sections of key nuclear reactions with the precision required by astrophysical models.Direct measurement of nuclear reaction cross sections is an important method of investigating how nuclear reactions infuence stellar evolution.Given the challenges involved in measuring the extremely low crosssections of nuclear reactions in the Gamow peak and preparing radioactive targets,indirect methods,such as the transfer reaction,coulomb dissociation,and surrogate ratio methods,have been developed over the past several decades.These are powerful tools in the investigation of,for example,neutron-capture(n,r)reactions with short-lived radioactive isotopes.However,direct measurement is still preferable,such as in the case of reactions involving light and stable nuclei.As an essential part of stellar evolution,these low-energy stable nuclear reactions have been of particular interest in recent years.To overcome the diffculties in measurements near or deeply within the Gamow window,the combination of an underground laboratory and high-exposure accelerator/detector complex is currently the optimal solution.Therefore,underground experiments have emerged as a new and promising direction of research.In addition,to better simulate the stellar environment in the laboratory,research on nuclear physics under laser-driven plasma conditions has gradually become a frontier hotspot.In recent years,the CIAE team conducted a series of distinctive nuclear astrophysics studies,relying on the Jinping Underground Nuclear Astrophysics platform and accelerators in Earth’s surface laboratories,including the Beijing Radioactive Ion beam Facility,as well as other scientifc platforms at home and abroad.This research covered nuclear theories,numerical models,direct measurements,indirect measurements,and other novel approaches,achieving great interdisciplinary research results,with high-level academic publications and signifcant international impacts.This article reviews the above research and predicts future developments.
基金Supported by Basic and Forward-Looking Project of the Science and Technology Department of SINOPEC(P22213-4)。
文摘Laboratory experiments,numerical simulations and fracturing technology were combined to address the problems in shale oil recovery by CO_(2)injection.The laboratory experiments were conducted to investigate the displacement mechanisms of shale oil extraction by CO_(2)injection,and the influences of CO_(2)pre-pad on shale mechanical properties.Numerical simulations were performed about influences of CO_(2)pre-pad fracturing and puff-n-huff for energy replenishment on the recovery efficiency.The findings obtained were applied to the field tests of CO_(2)pre-pad fracturing and single well puff-n-huff.The results show that the efficiency of CO_(2)puff-n-huff is affected by micro-and nano-scale effect,kerogen,adsorbed oil and so on,and a longer soaking time in a reasonable range leads to a higher exploitation degree of shale oil.In the"injection+soaking"stage,the exploitation degree of heavy hydrocarbons is enhanced by CO_(2)through its effects of solubility-diffusion and mass-transfer.In the"huff"stage,crude oil in large pores is displaced by CO_(2)to surrounding larger pores or bedding fractures and finally flows to the production well.The injection of CO_(2)pre-pad is conducive to keeping the rock brittle and reducing the fracture breakdown pressure,and the CO_(2)is liable to filter along the bedding surface,thereby creating a more complex fracture.Increasing the volume of CO_(2)pre-pad can improve the energizing effect,and enhance the replenishment of formation energy.Moreover,the oil recovery is more enhanced by CO_(2)huff-n-puff with the lower shale matrix permeability,the lower formation pressure,and the larger heavy hydrocarbon content.The field tests demonstrate a good performance with the pressure maintained well after CO_(2)pre-pad fracturing,the formation energy replenished effectively after CO_(2)huff-n-puff in a single well,and the well productivity improved.
文摘The SSRF phase-Ⅱ beamline project was launched in 2016. Its major goal was to establish a systematic state-of-the-art experimental facility for third-generation synchrotron radiation to solve problems in cutting-edge science and technology.Currently, the construction is fully completed. All 16 newly built beamlines with nearly 60 experimental methods passed acceptance testing by the Chinese Academy of Sciences and are in operation.
基金supported by the National Natural Science Foundation of China(Nos.52125402 and 52174084)the Natural Science Foundation of Sichuan Province of China(No.2022NSFSC0005).
文摘The deep earth,deep sea,and deep space are the main parts of the national“three deep”strategy,which is in the forefront of the strategic deployment clearly defined in China’s 14th Five-Year Plan(2021-2025)and the Long-Range Objectives Through the Year 2035.It is important to reveal the evolutionary process and mechanism of deep tectonics to understand the earth’s past,present and future.The academic con-notation of Geology in Time has been given for the first time,which refers to the multi-field evolution response process of geological bodies at different time and spatial scales caused by geological processes inside and outside the Earth.Based on the deep in situ detection space and the unique geological envi-ronment of China Jinping Underground Laboratory,the scientific issue of the correlation mechanism and law between deep internal time-varying and shallow geological response is given attention.Innovative research and frontier exploration on deep underground in situ geo-information detection experiments for Geology in Time are designed to be carried out,which will have the potential to explore the driving force of Geology in Time,reveal essential laws of deep earth science,and explore innovative technologies in deep underground engineering.
基金funded by the National Key Research and Development Plan(No.2022YFC3203200)Department of Science and Technology of Guangdong Province(No.2021ZT09G087)the National Natural Science Foundation Project of China(No.42167025).
文摘Complexities in mechanical behaviours of rock masses mainly stem from inherent discontinuities,which calls for advanced bolt-grouting techniques for stability enhancement.Understanding the mechanical properties of bolt-grouted fractured rock mass(BGFR)and developing accurate prediction methods are crucial to optimize the BGFR support strategies.This paper establishes a new elastoplastic(E-P)model based on the orthotropic and the Mohr-Coulomb(M-C)plastic-yielding criteria.The elastic parameters of the model were derived through a meso-mechanical analysis of composite materials mechanics(CMM).Laboratory BGFR specimens were prepared and uniaxial compression test and variable-angle shear test considering different bolt arrangements were carried out to obtain the mechanical parameters of the specimens.Results showed that the anisotropy of BGFR mainly depends on the relative volume content of each component material in a certain direction.Moreover,the mechanical parameters deduced from the theory of composite materials which consider the short fibre effect are shown to be in good agreement with those determined by laboratory experiments,and the variation rules maintained good consistency.Last,a case study of a real tunnel project is provided to highlight the effectiveness,validity and robustness of the developed E-P model in prediction of stresses and deformations.
文摘In astrophysics, the boundary conditions for plasma phenomena are provided by nature and the astronomer faces the problem of understanding them from a variety of observations [Hester J J et al 1996 Astrophys. J. 456 225], on the other hand, in laboratory plasma experiments the electromagnetic boundary conditions become a major problem in the set-up of the machine that produces the plasma, an issue that has to be investigated step by step and to be modified and adapted with great patience, in particular in the case of an innovative plasma confinement experiment. The PROTO-SPHERA machine [Alladio F et al 2006 Nucl. Fusion 46 S613] is a magnetic confinement experiment, that emulates in the laboratory the jet + torus plasma configurations often observed in astrophysics: an inner magnetized jet of plasma centered on the(approximate) axis of symmetry and surrounded by a magnetized plasma torus orthogonal to this jet. The PROTO-SPHERA plasma is simply connected, i.e., no metal current conducting rod is linked to the plasma torus, while instead it is the inner magnetized plasma jet(in the following always called the plasma centerpost) that is linked to the torus. It is mandatory that no spurious plasma current path modifies the optimal shape of the plasma centerpost. Moreover, as the plasma torus is produced and sustained, in absence of any applied inductive electric field, by the inner plasma centerpost through magnetic reconnections [Taylor J B and Turner M F 1989 Nucl.Fusion 29 219], it is required as well that spurious current paths do not surround the torus on its outboard, in order not to lower the efficiency of the magnetic reconnections that maintain the plasma torus at the expense of the plasma centerpost. Boundary conditions have been corrected,up to the point that the first sustainment in steady state has been achieved for the combined plasma.
基金This work was supported by the National Key Research and Development Program of China(Nos.2021YFA1601300 and 2022YFA1604703)From-0-to-1 Original Innovation Program of Chinese Academy of Sciences(No.ZDBS-LY-SLH014)+1 种基金International Partner Program of Chinese Academy of Sciences(No.GJHZ2067)National Natural Science Foundation of China Youth Science Fund Project(No.12105110).
文摘Observing nuclear neutrinoless double beta (0vββ) decay would be a revolutionary result in particle physics.Observing such a decay would prove that the neutrinos are their own antiparticles,help to study the absolute mass of neutrinos,explore the origin of their mass,and may explain the matter-antimatter asymmetry in our universe by lepton number violation.We propose developing a time projection chamber (TPC) using high-pressure ^(82)SeF_(6) gas and Topmetal silicon sensors for readout in the China Jinping Underground Laboratory (CJPL) to search for neutrinoless double beta decay of82Se,called the NvDEx experiment.Besides being located at CJPL with the world’s thickest rock shielding,NvDEx combines the advantages of the high Qββ(2.996 MeV) of82Se and the TPC’s ability to distinguish signal and background events using their different topological characteristics.This makes NvDEx unique,with great potential for low-background and high-sensitivity 0 vββsearches.NvDEx-100,a NvDEx experiment phase with 100 kg of SeF_(6)gas,is being built,with plans to complete installation at CJPL by 2025.This report introduces 0 vββ physics,the NvDEx concept and its advantages,and the schematic design of NvDEx-100,its subsystems,and background and sensitivity estimation.
基金Supported by International Meridian Circle Program Headquarters,China-Brazil Joint Laboratory for Space Weather(Y42347A99S)。
文摘In 2024,the Chinese Meridian Project(CMP)completed its construction,deploying 282 instruments across 31 stations.This achievement not only provides a robust foundation but also serves as a reference template for the International Meridian Circle Program(IMCP).The IMCP aims to integrate and establish a comprehensive network of ground-based monitoring stations designed to track the propagation of space weather events from the Sun to Earth.Additionally,it monitors various disturbances generated within the Earth system that impact geospace.Over the past two years,significant progress has been made on the IMCP.In particular,the second phase of construction for the China-Brazil Joint Laboratory for Space Weather has been completed,and the North Pole and Southeast Asia networks are under active construction.The 2024 IMCP joint observation campaign was successfully conducted.To facilitate these developments,the scientific program committee of IMCP was established,following the success of 2023 IMCP workshop and the space weather school,which was co-hosted with the Asia-Pacific Space Cooperation Organization(APSCO)and sponsored by Chinese Academy of Sciences(CAS)and Scientific Committee on Solar-Terrestrial Physics(SCOSTEP).Preparations are now underway for the 2024 workshop in collaboration with the National Institute for Space Research(INPE)in Brazil.