Developmental and reproductive toxicity(DART)endpoint entails a toxicological assessment of all developmental stages and reproductive cycles of an organism.In silico tools to predict DART will provide a method to asse...Developmental and reproductive toxicity(DART)endpoint entails a toxicological assessment of all developmental stages and reproductive cycles of an organism.In silico tools to predict DART will provide a method to assess this complex toxicity endpoint and will be valuable for screening emerging pollutants as well as for m anaging new chemicals in China.Currently,there are few published DART prediction models in China,but many related research and development projects are in progress.In 2013,WU et al.published an expert rule-based DART decision tree(DT).This DT relies on known chemical structures linked to DART to forecast DART potential of a given chemical.Within this procedure,an accurate DART data interpretation is the foundation of building and expanding the DT.This paper excerpted case studies demonstrating DART data curation and interpretation of four chemicals(including 8-hydroxyquinoline,3,5,6-trichloro-2-pyridinol,thiacloprid,and imidacloprid)to expand the existing DART DT.Chemicals were first selected from the database of Solid Waste and Chemicals Management Center,Ministry of Ecology and Environment(MEESCC)in China.The structures of these 4 chemicals were analyzed and preliminarily grouped by chemists based on core structural features,functional groups,receptor binding property,metabolism,and possible mode of actions.Then,the DART conclusion was derived by collecting chemical information,searching,integrating,and interpreting DART data by the toxicologists.Finally,these chemicals were classified into either an existing category or a new category via integrating their chemical features,DART conclusions,and biological properties.The results showed that 8-hydroxyquinoline impacted estrous cyclicity,s exual organ weights,and embryonal development,and 3,5,6-trichloro-2-pyridinol caused central nervous system(CNS)malformations,which were added to an existing subcategory 8e(aromatic compounds with multi-halogen and nitro groups)of the DT.Thiacloprid caused dystocia and fetal skeletal malformation,and imidacloprid disrupted the endocrine system and male fertility.They both contain 2-chloro-5-methylpyridine substituted imidazolidine c yclic ring,which were expected to create a new category of neonicotinoids.The current work delineates a t ransparent process of curating toxicological data for the purpose of DART data interpretation.In the presence of sufficient related structures and DART data,the DT can be expanded by iteratively adding chemicals within the a pplicable domain of each category or subcategory.This DT can potentially serve as a tool for screening emerging pollutants and assessing new chemicals in China.展开更多
With respect to the multiple attribute decision making problems with linguistic preference relations on alternatives in the form of incomplete linguistic judgment matrix, a method is proposed to analyze the decision p...With respect to the multiple attribute decision making problems with linguistic preference relations on alternatives in the form of incomplete linguistic judgment matrix, a method is proposed to analyze the decision problem. The incomplete linguistic judgment matrix is transformed into incomplete fuzzy judgment matrix and an optimization model is developed on the basis of incomplete fuzzy judgment matrix provided by the decision maker and the decision matrix to determine attribute weights by Lagrange multiplier method. Then the overall values of all alternatives are calculated to rank them. A numerical example is given to illustrate the feasibility and practicality of the proposed method.展开更多
The ranking problem is studied when the pairwise comparisons values are unoertain in the analytic hierarchy process （AHP）. The method of constructing the judgment matrix is presented when the pairwise comparisons va...The ranking problem is studied when the pairwise comparisons values are unoertain in the analytic hierarchy process （AHP）. The method of constructing the judgment matrix is presented when the pairwise comparisons values are denoted by the unascertained three-valued reciprocal scales. By turning the reciprocal judgment matrix into attribute judgment matrix, the method to check the consistency of the pairwise comparisons judgment matrix and the calculation method of weighting coefficients are given. Finally, numerical examples are given to illustrate the effectiveness of the proposed method.展开更多
A new method in making judgment matrix is proposed based on a basic value of “importance” and a relative measure level of “importance”. Factors affecting petroleum exploration are analyzed and Experts’ judgment m...A new method in making judgment matrix is proposed based on a basic value of “importance” and a relative measure level of “importance”. Factors affecting petroleum exploration are analyzed and Experts’ judgment matrix on a geologic formation is given. Expected value of each factor is computed and the volume of recoverable oil is estimated.展开更多
Threat-judgment is a complicated fuzzy inference problem. Up to now no relevant unified theory and measur-ing standard have been developed. It is very difficult to establish a threat-judgment model with high reliabili...Threat-judgment is a complicated fuzzy inference problem. Up to now no relevant unified theory and measur-ing standard have been developed. It is very difficult to establish a threat-judgment model with high reliability in the airdefense system for the naval warships. Air target threat level judgment is an important component in naval warship com-bat command decision-making systems. According to the threat level judgment of air targets during the air defense of sin-gle naval warship, a fuzzy pattern recognition model for judging the threat from air targets is established. Then an algo-rithm for identifying the parameters in the model is presented. The model has an adaptive feature and can dynamicallyupdate its parameters according to the state change of the attacking targets and the environment. The method presentedhere can be used for the air defense system threat judgment in the naval warships.展开更多
In this paper, decision making in complex environment is considered and an approach integrating quantitative decision model with qualitative judgment is proposed. The concept of belief degree for quantitative decision...In this paper, decision making in complex environment is considered and an approach integrating quantitative decision model with qualitative judgment is proposed. The concept of belief degree for quantitative decision model in a complex environment is presented. The integration in formulation and reasoning of quantitative model with qualitative judgment is studied. The combination of various belief degree generated by quantitative model and qualitative judgment is discussed. A decision rule of tradeoff between optimality and belief degree of optimality is proposed.展开更多
Political skill is a critical interpersonal competency.However,the self-reported political skill scale is unsuitable for personnel selection beacuse it may lead to socially desirable responses,thereby compromising the...Political skill is a critical interpersonal competency.However,the self-reported political skill scale is unsuitable for personnel selection beacuse it may lead to socially desirable responses,thereby compromising the authenticity of the test scores.Consequently,the absence of a valid assessment method limits the application of political skill in selection con-texts.In this study,we applied the situational judgment test(SJT)method to measure political skill and conducted two sub-studies to evaluate the reliability and validity of the situational judgment test of political skill(SJT-PS).Study 1 focused on the development and initial testing of the SJT-PS.The results demonstrated that the SJT-PS possessed strong structural validity and reliability.Study 2 aimed to assess the criterion-related and incremental validity of the SJT-PS.To evaluate the predictive validity of the SJT-PS in selection contexts,we first compared the correlations between the SJT-PS and self-reported political skill with social desirability.Subsequently,we selected team-member exchange(TMX)and workplace popularity as criteria.The results indicated that the SJT-PS was less affected by social desirability,while self-reported political skill exhibited a significant positive correlation with social desirability.Additionally,the SJT-PS positively pre-dicted TMX and workplace popularity and demonstrated incremental validity over the self-reported political skill scale.展开更多
The relationship between mediation and the judgment directly affect the practical effects of judicial power operation,and have important influence on judicial practice. Mediation and judgment have been contradicting e...The relationship between mediation and the judgment directly affect the practical effects of judicial power operation,and have important influence on judicial practice. Mediation and judgment have been contradicting each other for a long time,which is the result of the social situation,national policies and other factors intertwined. Practically the alienation of the relationship between mediation and judgment,such as phenomenon of attaching more importance to mediation and less importance to judgment,arbitrary application of mediation,as well as failure to give full play to the due function of mediation and judgment,have deep social reasons,and lead to certain degree of harm. Both mediation and judgment are important means to effectively resolve disputes,with functional complementation of mediation and judgment. Meanwhile judgment serves as an important guarantee for mediation to function. Therefore,to realize scientific selection based on combination of mediation and judgment,it must adhere to classification management over applicable scope of mediation and judgment,application conditions of mediation and judgment,timing of applying mediation and judgment,and supporting mechanismfor scientific selection of mediation and judgment.展开更多
A vicious script detection method based on statistic is proposed by analyzing the vicious script in the hypertext markup language(HTML).We utilize the judgment matrix approach which is one of the subjective weighting ...A vicious script detection method based on statistic is proposed by analyzing the vicious script in the hypertext markup language(HTML).We utilize the judgment matrix approach which is one of the subjective weighting approaches to set the different weights for various statistic methods.Then we make use of the weighted geometric method to perfect the statistic results.Experimental results show the validity of this method.展开更多
文摘Developmental and reproductive toxicity(DART)endpoint entails a toxicological assessment of all developmental stages and reproductive cycles of an organism.In silico tools to predict DART will provide a method to assess this complex toxicity endpoint and will be valuable for screening emerging pollutants as well as for m anaging new chemicals in China.Currently,there are few published DART prediction models in China,but many related research and development projects are in progress.In 2013,WU et al.published an expert rule-based DART decision tree(DT).This DT relies on known chemical structures linked to DART to forecast DART potential of a given chemical.Within this procedure,an accurate DART data interpretation is the foundation of building and expanding the DT.This paper excerpted case studies demonstrating DART data curation and interpretation of four chemicals(including 8-hydroxyquinoline,3,5,6-trichloro-2-pyridinol,thiacloprid,and imidacloprid)to expand the existing DART DT.Chemicals were first selected from the database of Solid Waste and Chemicals Management Center,Ministry of Ecology and Environment(MEESCC)in China.The structures of these 4 chemicals were analyzed and preliminarily grouped by chemists based on core structural features,functional groups,receptor binding property,metabolism,and possible mode of actions.Then,the DART conclusion was derived by collecting chemical information,searching,integrating,and interpreting DART data by the toxicologists.Finally,these chemicals were classified into either an existing category or a new category via integrating their chemical features,DART conclusions,and biological properties.The results showed that 8-hydroxyquinoline impacted estrous cyclicity,s exual organ weights,and embryonal development,and 3,5,6-trichloro-2-pyridinol caused central nervous system(CNS)malformations,which were added to an existing subcategory 8e(aromatic compounds with multi-halogen and nitro groups)of the DT.Thiacloprid caused dystocia and fetal skeletal malformation,and imidacloprid disrupted the endocrine system and male fertility.They both contain 2-chloro-5-methylpyridine substituted imidazolidine c yclic ring,which were expected to create a new category of neonicotinoids.The current work delineates a t ransparent process of curating toxicological data for the purpose of DART data interpretation.In the presence of sufficient related structures and DART data,the DT can be expanded by iteratively adding chemicals within the a pplicable domain of each category or subcategory.This DT can potentially serve as a tool for screening emerging pollutants and assessing new chemicals in China.
基金the National Natural Science Foundation of China (70701008)National Science Foundationfor Distinguished Young Scholars of China (70525002)
文摘With respect to the multiple attribute decision making problems with linguistic preference relations on alternatives in the form of incomplete linguistic judgment matrix, a method is proposed to analyze the decision problem. The incomplete linguistic judgment matrix is transformed into incomplete fuzzy judgment matrix and an optimization model is developed on the basis of incomplete fuzzy judgment matrix provided by the decision maker and the decision matrix to determine attribute weights by Lagrange multiplier method. Then the overall values of all alternatives are calculated to rank them. A numerical example is given to illustrate the feasibility and practicality of the proposed method.
文摘The ranking problem is studied when the pairwise comparisons values are unoertain in the analytic hierarchy process （AHP）. The method of constructing the judgment matrix is presented when the pairwise comparisons values are denoted by the unascertained three-valued reciprocal scales. By turning the reciprocal judgment matrix into attribute judgment matrix, the method to check the consistency of the pairwise comparisons judgment matrix and the calculation method of weighting coefficients are given. Finally, numerical examples are given to illustrate the effectiveness of the proposed method.
文摘A new method in making judgment matrix is proposed based on a basic value of “importance” and a relative measure level of “importance”. Factors affecting petroleum exploration are analyzed and Experts’ judgment matrix on a geologic formation is given. Expected value of each factor is computed and the volume of recoverable oil is estimated.
基金This project was supported by the National Defense Foundation of China(40108070103)
文摘Threat-judgment is a complicated fuzzy inference problem. Up to now no relevant unified theory and measur-ing standard have been developed. It is very difficult to establish a threat-judgment model with high reliability in the airdefense system for the naval warships. Air target threat level judgment is an important component in naval warship com-bat command decision-making systems. According to the threat level judgment of air targets during the air defense of sin-gle naval warship, a fuzzy pattern recognition model for judging the threat from air targets is established. Then an algo-rithm for identifying the parameters in the model is presented. The model has an adaptive feature and can dynamicallyupdate its parameters according to the state change of the attacking targets and the environment. The method presentedhere can be used for the air defense system threat judgment in the naval warships.
文摘In this paper, decision making in complex environment is considered and an approach integrating quantitative decision model with qualitative judgment is proposed. The concept of belief degree for quantitative decision model in a complex environment is presented. The integration in formulation and reasoning of quantitative model with qualitative judgment is studied. The combination of various belief degree generated by quantitative model and qualitative judgment is discussed. A decision rule of tradeoff between optimality and belief degree of optimality is proposed.
基金supported by the National Nature Science Foundation of China(7191001010)。
文摘Political skill is a critical interpersonal competency.However,the self-reported political skill scale is unsuitable for personnel selection beacuse it may lead to socially desirable responses,thereby compromising the authenticity of the test scores.Consequently,the absence of a valid assessment method limits the application of political skill in selection con-texts.In this study,we applied the situational judgment test(SJT)method to measure political skill and conducted two sub-studies to evaluate the reliability and validity of the situational judgment test of political skill(SJT-PS).Study 1 focused on the development and initial testing of the SJT-PS.The results demonstrated that the SJT-PS possessed strong structural validity and reliability.Study 2 aimed to assess the criterion-related and incremental validity of the SJT-PS.To evaluate the predictive validity of the SJT-PS in selection contexts,we first compared the correlations between the SJT-PS and self-reported political skill with social desirability.Subsequently,we selected team-member exchange(TMX)and workplace popularity as criteria.The results indicated that the SJT-PS was less affected by social desirability,while self-reported political skill exhibited a significant positive correlation with social desirability.Additionally,the SJT-PS positively pre-dicted TMX and workplace popularity and demonstrated incremental validity over the self-reported political skill scale.
文摘The relationship between mediation and the judgment directly affect the practical effects of judicial power operation,and have important influence on judicial practice. Mediation and judgment have been contradicting each other for a long time,which is the result of the social situation,national policies and other factors intertwined. Practically the alienation of the relationship between mediation and judgment,such as phenomenon of attaching more importance to mediation and less importance to judgment,arbitrary application of mediation,as well as failure to give full play to the due function of mediation and judgment,have deep social reasons,and lead to certain degree of harm. Both mediation and judgment are important means to effectively resolve disputes,with functional complementation of mediation and judgment. Meanwhile judgment serves as an important guarantee for mediation to function. Therefore,to realize scientific selection based on combination of mediation and judgment,it must adhere to classification management over applicable scope of mediation and judgment,application conditions of mediation and judgment,timing of applying mediation and judgment,and supporting mechanismfor scientific selection of mediation and judgment.
基金Sponsored by the National 242 Information Security Project (2005A10 )and( 2007F40)the National Defence Basic Scientific Research Project(C1120060497)
文摘A vicious script detection method based on statistic is proposed by analyzing the vicious script in the hypertext markup language(HTML).We utilize the judgment matrix approach which is one of the subjective weighting approaches to set the different weights for various statistic methods.Then we make use of the weighted geometric method to perfect the statistic results.Experimental results show the validity of this method.
