In order to enhance the control performance of piezo-positioning system,the influence of hysteresis characteristics and its compensation method are studied.Hammerstein model is used to represent the dynamic hysteresis...In order to enhance the control performance of piezo-positioning system,the influence of hysteresis characteristics and its compensation method are studied.Hammerstein model is used to represent the dynamic hysteresis nonlinear characteristics of piezo-positioning actuator.The static nonlinear part and dynamic linear part of the Hammerstein model are represented by models obtained through the Prandtl-Ishlinskii(PI)model and Hankel matrix system identification method,respectively.This model demonstrates good generalization capability for typical input frequencies below 200 Hz.A sliding mode inverse compensation tracking control strategy based on P-I inverse model and integral augmentation is proposed.Experimental results show that compared with PID inverse compensation control and sliding mode control without inverse compensation,the sliding mode inverse compensation control has a more ideal step response and no overshoot,moreover,the settling time is only 6.2 ms.In the frequency domain,the system closed-loop tracking bandwidth reaches 119.9 Hz,and the disturbance rejection bandwidth reaches 86.2 Hz.The proposed control strategy can effectively compensate the hysteresis nonlinearity,and improve the tracking accuracy and antidisturbance capability of piezo-positioning system.展开更多
芝麻是八大类食物过敏原之一,快速准确识别芝麻过敏原对预防其过敏有重要意义。核酸适配体可以高效识别靶标过敏原,在过敏原检测中有良好的应用前景。为了获得芝麻主要过敏原Ses i 2的特异性核酸适体,本研究以Ses i 2为靶标,通过磁珠筛...芝麻是八大类食物过敏原之一,快速准确识别芝麻过敏原对预防其过敏有重要意义。核酸适配体可以高效识别靶标过敏原,在过敏原检测中有良好的应用前景。为了获得芝麻主要过敏原Ses i 2的特异性核酸适体,本研究以Ses i 2为靶标,通过磁珠筛选法(磁珠-SELEX)开展10轮筛选,经由高通量测序获得6条候补序列(S1~S6),并进行家族性、同源性分析及二级结构预测。结果表明,6条候选核酸适体的重复率可达46.38%,其自由能在-9.02到-2.47 kcal·moL^(-1)之间,根据自由能能量稳定原则,S1和S5吉布斯自由能最低最稳定,分别为-6.70和-9.02 kcal·moL^(-1)。利用ELISA试验进行亲和力测试,结果表明核酸适体S1和S2的亲和能力较强,S1:KD=67.02 nmol·L^(-1),R2=0.925 8,S2:KD=97.65 nmol·L^(-1),R2=0.795 1。核酸适体S1与过敏原Ses i 2的结合力和其他过敏原蛋白相比有显著差异,可视为具有特异性。本研究最终获得一条兼具良好亲和力和特异性的核酸适体S1,为芝麻过敏原快速检测提供了技术支撑。展开更多
In audio stream containing multiple speakers, speaker diarization aids in ascertaining "who speak when". This is an unsupervised task as there is no prior information about the speakers. It labels the speech...In audio stream containing multiple speakers, speaker diarization aids in ascertaining "who speak when". This is an unsupervised task as there is no prior information about the speakers. It labels the speech signal conforming to the identity of the speaker, namely, input audio stream is partitioned into homogeneous segments. In this work, we present a novel speaker diarization system using the Tangent weighted Mel frequency cepstral coefficient(TMFCC) as the feature parameter and Lion algorithm for the clustering of the voice activity detected audio streams into particular speaker groups. Thus the two main tasks of the speaker indexing, i.e., speaker segmentation and speaker clustering, are improved. The TMFCC makes use of the low energy frame as well as the high energy frame with more effect, improving the performance of the proposed system. The experiments using the audio signal from the ELSDSR corpus datasets having three speakers, four speakers and five speakers are analyzed for the proposed system. The evaluation of the proposed speaker diarization system based on the tracking distance, tracking time as the evaluation metrics is done and the experimental results show that the speaker diarization system with the TMFCC parameterization and Lion based clustering is found to be superior over existing diarization systems with 95% tracking accuracy.展开更多
综合能源系统(integrated energy system,IES)以其高度灵活、环境友好的特点,在实现低碳经济和提高能源效率方面具有巨大潜力。然而,现有的IES建模方法难以挖掘氢能多设备的协同耦合性、且调度策略缺少市场机制的支持。因此,文中提出一...综合能源系统(integrated energy system,IES)以其高度灵活、环境友好的特点,在实现低碳经济和提高能源效率方面具有巨大潜力。然而,现有的IES建模方法难以挖掘氢能多设备的协同耦合性、且调度策略缺少市场机制的支持。因此,文中提出一种综合考虑绿色证书交易、阶梯型碳交易和需求响应的含氢IES优化调度策略。首先,建立基于电转气(power-to-gas,P2G)两阶段运行的氢能多元利用模型,推动新能源的使用;然后,建立绿证-碳联合交易机制,通过市场激励减少对化石燃料的依赖;最后,考虑综合需求响应优化用户侧用能行为,建立以经济运行成本最小为目标函数的IES优化调度模型,并通过CPLEX求解器进行求解。算例结果表明,文中所提模型能够实现IES多能耦合,提高新能源的消纳能力,减少碳排放量。展开更多
In 1996,two shallow ice cores were drilled at 7100m ASL. on the Dasuopu Glacier in the Xixiabangma in the middle Himalayas.Analytical results i ndicated that Cl\+- and Na\++ concentrations showed seasonal variations,a...In 1996,two shallow ice cores were drilled at 7100m ASL. on the Dasuopu Glacier in the Xixiabangma in the middle Himalayas.Analytical results i ndicated that Cl\+- and Na\++ concentrations showed seasonal variations,and there was a very good relation between them,which reflects that the moisture at the drilling site mainly came from oceans.An interesting phenomenon was that the changes in the ratio of Cl\+- to Na\++ in these cores might be associated with Indian summer monsoon rainfall in recent years (Fig.1).展开更多
文摘In order to enhance the control performance of piezo-positioning system,the influence of hysteresis characteristics and its compensation method are studied.Hammerstein model is used to represent the dynamic hysteresis nonlinear characteristics of piezo-positioning actuator.The static nonlinear part and dynamic linear part of the Hammerstein model are represented by models obtained through the Prandtl-Ishlinskii(PI)model and Hankel matrix system identification method,respectively.This model demonstrates good generalization capability for typical input frequencies below 200 Hz.A sliding mode inverse compensation tracking control strategy based on P-I inverse model and integral augmentation is proposed.Experimental results show that compared with PID inverse compensation control and sliding mode control without inverse compensation,the sliding mode inverse compensation control has a more ideal step response and no overshoot,moreover,the settling time is only 6.2 ms.In the frequency domain,the system closed-loop tracking bandwidth reaches 119.9 Hz,and the disturbance rejection bandwidth reaches 86.2 Hz.The proposed control strategy can effectively compensate the hysteresis nonlinearity,and improve the tracking accuracy and antidisturbance capability of piezo-positioning system.
文摘芝麻是八大类食物过敏原之一,快速准确识别芝麻过敏原对预防其过敏有重要意义。核酸适配体可以高效识别靶标过敏原,在过敏原检测中有良好的应用前景。为了获得芝麻主要过敏原Ses i 2的特异性核酸适体,本研究以Ses i 2为靶标,通过磁珠筛选法(磁珠-SELEX)开展10轮筛选,经由高通量测序获得6条候补序列(S1~S6),并进行家族性、同源性分析及二级结构预测。结果表明,6条候选核酸适体的重复率可达46.38%,其自由能在-9.02到-2.47 kcal·moL^(-1)之间,根据自由能能量稳定原则,S1和S5吉布斯自由能最低最稳定,分别为-6.70和-9.02 kcal·moL^(-1)。利用ELISA试验进行亲和力测试,结果表明核酸适体S1和S2的亲和能力较强,S1:KD=67.02 nmol·L^(-1),R2=0.925 8,S2:KD=97.65 nmol·L^(-1),R2=0.795 1。核酸适体S1与过敏原Ses i 2的结合力和其他过敏原蛋白相比有显著差异,可视为具有特异性。本研究最终获得一条兼具良好亲和力和特异性的核酸适体S1,为芝麻过敏原快速检测提供了技术支撑。
基金国家自然科学基金联合基金项目(U21A20485)浙江省高等教育“十四五”本科教育教学改革项目(jg20220019)+3 种基金浙江省产学合作协同育人项目(202018)浙江大学2023年度本科教学创新实践项目重点项目(202309)浙江省基础公益研究计划项目(LGG22F030008)浙江大学第一批AI For Education系列实证教学研究项目(202402)。
文摘In audio stream containing multiple speakers, speaker diarization aids in ascertaining "who speak when". This is an unsupervised task as there is no prior information about the speakers. It labels the speech signal conforming to the identity of the speaker, namely, input audio stream is partitioned into homogeneous segments. In this work, we present a novel speaker diarization system using the Tangent weighted Mel frequency cepstral coefficient(TMFCC) as the feature parameter and Lion algorithm for the clustering of the voice activity detected audio streams into particular speaker groups. Thus the two main tasks of the speaker indexing, i.e., speaker segmentation and speaker clustering, are improved. The TMFCC makes use of the low energy frame as well as the high energy frame with more effect, improving the performance of the proposed system. The experiments using the audio signal from the ELSDSR corpus datasets having three speakers, four speakers and five speakers are analyzed for the proposed system. The evaluation of the proposed speaker diarization system based on the tracking distance, tracking time as the evaluation metrics is done and the experimental results show that the speaker diarization system with the TMFCC parameterization and Lion based clustering is found to be superior over existing diarization systems with 95% tracking accuracy.
文摘综合能源系统(integrated energy system,IES)以其高度灵活、环境友好的特点,在实现低碳经济和提高能源效率方面具有巨大潜力。然而,现有的IES建模方法难以挖掘氢能多设备的协同耦合性、且调度策略缺少市场机制的支持。因此,文中提出一种综合考虑绿色证书交易、阶梯型碳交易和需求响应的含氢IES优化调度策略。首先,建立基于电转气(power-to-gas,P2G)两阶段运行的氢能多元利用模型,推动新能源的使用;然后,建立绿证-碳联合交易机制,通过市场激励减少对化石燃料的依赖;最后,考虑综合需求响应优化用户侧用能行为,建立以经济运行成本最小为目标函数的IES优化调度模型,并通过CPLEX求解器进行求解。算例结果表明,文中所提模型能够实现IES多能耦合,提高新能源的消纳能力,减少碳排放量。
文摘In 1996,two shallow ice cores were drilled at 7100m ASL. on the Dasuopu Glacier in the Xixiabangma in the middle Himalayas.Analytical results i ndicated that Cl\+- and Na\++ concentrations showed seasonal variations,and there was a very good relation between them,which reflects that the moisture at the drilling site mainly came from oceans.An interesting phenomenon was that the changes in the ratio of Cl\+- to Na\++ in these cores might be associated with Indian summer monsoon rainfall in recent years (Fig.1).
