Because of its excellent dose distribution,proton therapy is becoming increasingly popular in the medical application of cancer treatment.A synchrotron-based proton therapy facility was designed and constructed in Sha...Because of its excellent dose distribution,proton therapy is becoming increasingly popular in the medical application of cancer treatment.A synchrotron-based proton therapy facility was designed and constructed in Shanghai.The synchrotron,beam delivery system,and other technical systems were commissioned and reached their expected performances.After a clinical trial of 47 patients was finished,the proton therapy facility obtained a registration certificate from the National Medical Products Administration.The characteristics of the accelerator and treatment systems are described in this article.展开更多
The Xi'an Proton Application Facility(XiPAF)is a facility dedicated to the experimental simulation of the space radiation environment.The facility uses a compact synchrotron as its final-stage accelerator.The sync...The Xi'an Proton Application Facility(XiPAF)is a facility dedicated to the experimental simulation of the space radiation environment.The facility uses a compact synchrotron as its final-stage accelerator.The synchrotron can accelerate a proton beam from 7 to 230 MeV.Physical design results show that the radio frequency(RF) acceleration system should work in the frequency range of 1—6 MHz and provide a maximum voltage of >800 V.To dilute the strong space charge effect during the injection period,we also aim to achieve multiharmonic acceleration.A compact RF acceleration system loaded with magnetic alloy cores has been designed and developed to fulfill these requirements.The preliminary test results show that the system can work normally with a gap voltage of 800 V.With a further RF power upgrade,the voltage can be improved to >1:2 kV.展开更多
The purpose of this study was to design a rapid-cycling synchrotron, making it capable of proton beam ultrahigh dose rate irradiation, inspired by laser accelerators. The design had to be cheap and simple. We consider...The purpose of this study was to design a rapid-cycling synchrotron, making it capable of proton beam ultrahigh dose rate irradiation, inspired by laser accelerators. The design had to be cheap and simple. We consider our design from six aspects: the lattice, injection, extraction, space charge effects, eddy current effects and energy switching. Efficiency and particle quantity must be addressed when injected. The space charge effects at the injection could affect particles' number. The eddy current effects in the vacuum chambers would affect the magnetic field itself and generate heat, all of which need to be taken into account. Fast extraction can obtain 10^(10) protons/pulse, equal to instantaneous dose rate up to 10~7 Gy/s in a very short time, while changing various extraction energies rapidly and easily to various deposition depths. In the further research, we expect to combine a delivery system with this accelerator to realize the FLASH irradiation.展开更多
文摘Because of its excellent dose distribution,proton therapy is becoming increasingly popular in the medical application of cancer treatment.A synchrotron-based proton therapy facility was designed and constructed in Shanghai.The synchrotron,beam delivery system,and other technical systems were commissioned and reached their expected performances.After a clinical trial of 47 patients was finished,the proton therapy facility obtained a registration certificate from the National Medical Products Administration.The characteristics of the accelerator and treatment systems are described in this article.
文摘The Xi'an Proton Application Facility(XiPAF)is a facility dedicated to the experimental simulation of the space radiation environment.The facility uses a compact synchrotron as its final-stage accelerator.The synchrotron can accelerate a proton beam from 7 to 230 MeV.Physical design results show that the radio frequency(RF) acceleration system should work in the frequency range of 1—6 MHz and provide a maximum voltage of >800 V.To dilute the strong space charge effect during the injection period,we also aim to achieve multiharmonic acceleration.A compact RF acceleration system loaded with magnetic alloy cores has been designed and developed to fulfill these requirements.The preliminary test results show that the system can work normally with a gap voltage of 800 V.With a further RF power upgrade,the voltage can be improved to >1:2 kV.
文摘The purpose of this study was to design a rapid-cycling synchrotron, making it capable of proton beam ultrahigh dose rate irradiation, inspired by laser accelerators. The design had to be cheap and simple. We consider our design from six aspects: the lattice, injection, extraction, space charge effects, eddy current effects and energy switching. Efficiency and particle quantity must be addressed when injected. The space charge effects at the injection could affect particles' number. The eddy current effects in the vacuum chambers would affect the magnetic field itself and generate heat, all of which need to be taken into account. Fast extraction can obtain 10^(10) protons/pulse, equal to instantaneous dose rate up to 10~7 Gy/s in a very short time, while changing various extraction energies rapidly and easily to various deposition depths. In the further research, we expect to combine a delivery system with this accelerator to realize the FLASH irradiation.
