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Effect of copper slag recovery on hydrometallurgical cut-off grades considering environmental aspects 被引量:2
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作者 AFSHIN AKBARI ESMAEIL RAHIMI 《Journal of Central South University》 SCIE EI CAS CSCD 2016年第4期798-807,共10页
Determining the hydrometallurgical cut-off grades specifies the destination of low grade materials and this is subjected to more benefits in mining. Copper production rate is considered as one of the fundamental issue... Determining the hydrometallurgical cut-off grades specifies the destination of low grade materials and this is subjected to more benefits in mining. Copper production rate is considered as one of the fundamental issues in hydrometallurgical cut-off grades determination. Slags are remarked as one of the main sources of copper. It is not only regarded as a waste but also identified as another resource extracting base metals. Slags are characterized by copper high grade. Thus, slag copper recovery can be led to different cut-off grades and net present value(NPV). The current research scrutinizes the effect of slag recovery by both flotation and hydrometallurgical methods on the hydrometallurgical cut-off grades. For this purpose, the optimum cut-off grade algorithms of hydrometallurgical methods are developed by considering associated environmental parameters, incomes and also the costs. Then, their optimum amounts are calculated with NPV maximization as an objective function. The results indicate that considering slag copper recovery in the hydrometallurgical cut-off grade algorithms reduces the environmental costs caused by slag dumping and leads to more NPV by 9%. 展开更多
关键词 HYDROMETALLURGY cut-off grades low grade materials WASTE floatation SLAG copper recovery environmental parameters slag dumping NPV maximization
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儿童积滞中医诊疗指南
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作者 赵霞 邱梦婷 +3 位作者 胡思源 秦艳虹 薛征 吴力群 《南京中医药大学学报》 北大核心 2025年第4期531-537,共7页
遵循基于证据的儿科常见病循证诊疗指南研制方法,通过文献检索、专家问卷调研、专家论证会、征求意见等环节,修订《儿童积滞中医诊疗指南》。修订内容包含指南范围、规范性引用文件、术语和定义、诊断、辨证、治疗、预防和调护建议等,... 遵循基于证据的儿科常见病循证诊疗指南研制方法,通过文献检索、专家问卷调研、专家论证会、征求意见等环节,修订《儿童积滞中医诊疗指南》。修订内容包含指南范围、规范性引用文件、术语和定义、诊断、辨证、治疗、预防和调护建议等,旨在更新积滞中医临床诊疗方案,为临床医师在儿童积滞防治中合理应用中医药诊疗方案提供重要的决策参考。 展开更多
关键词 中医 儿童 积滞 诊疗指南 标准 修订 GRADE 临床问题
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百令胶囊治疗呼吸系统疾病临床应用专家共识 被引量:1
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作者 明雨 俞邦 +6 位作者 黄常芮 张欣怡 常文婧 孙增涛 陈薇 张洪春 编制组 《中华中医药学刊》 北大核心 2025年第3期254-258,共5页
百令胶囊治疗呼吸系统疾病具有良好的临床疗效及安全性,已纳入国家医保药品目录、国家基本药物品种目录。百令胶囊于1991年上市,临床实际应用中存在适应证不规范、疗程界定不清、禁忌人群不明等问题。共识由中医肺系病、呼吸及危重症医... 百令胶囊治疗呼吸系统疾病具有良好的临床疗效及安全性,已纳入国家医保药品目录、国家基本药物品种目录。百令胶囊于1991年上市,临床实际应用中存在适应证不规范、疗程界定不清、禁忌人群不明等问题。共识由中医肺系病、呼吸及危重症医学领域的临床专家和方法学、药学专家共同制定,严格遵循中华中医药学会中成药临床应用专家共识步骤进行研制,以期指导临床规范使用百令胶囊治疗慢性支气管炎和其他呼吸系统疾病。共识采用问卷调查、专家访谈的形式收集临床应用建议,根据PICOS原则确定临床关注问题并进行证据评价和GRADE分级,采用名义组法产生推荐意见和共识建议,最终形成14条推荐意见和共识建议。共识进一步明确了百令胶囊治疗慢性支气管炎的适应症、中医证候、用法用量等,为其临床的合理使用提供参考。 展开更多
关键词 百令胶囊 慢性支气管炎 专家共识 GRADE
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星状神经节阻滞对比常规西药治疗失眠的Meta分析 被引量:2
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作者 宋研博 孙永康 +1 位作者 徐方飚 王新志 《介入放射学杂志》 北大核心 2025年第1期48-57,共10页
目的 评价星状神经节阻滞(stellate ganglion block, SGB)对比常规西药治疗失眠症的有效性和安全性。方法 检索PubMed、Embase、Cochrane Library、中国知网、万方数据知识服务平台、维普数据库和中国生物医学文献数据库自建库至2023年6... 目的 评价星状神经节阻滞(stellate ganglion block, SGB)对比常规西药治疗失眠症的有效性和安全性。方法 检索PubMed、Embase、Cochrane Library、中国知网、万方数据知识服务平台、维普数据库和中国生物医学文献数据库自建库至2023年6月13日收录的关于SGB对比常规西药治疗失眠的临床随机对照试验,通过NoteExpress v3.5软件进行文献筛选、Stata 17.0软件对数据进行Meta分析、TSA0.9.5.10Beta软件进行序贯分析、GRADEpro开发工具进行GRADE分级。结果 共纳入11篇文献,875例失眠患者。与常规西药相比,SGB在以下方面显示出一定优势:提高临床总有效率(RR_总=1.24,95%CI:1.16~1.32,P<0.01)、提高治疗后睡眠时间3 h以上患者的比率(RR_总=1.24,95%CI:1.09~1.41,P=0.001)、增加总睡眠时间(SMD=1.53,95%CI:0.89~2.16,P<0.01)、缩短睡眠潜伏期(MD=-14.08,95%CI:-18.72~-9.43,P<0.01)、降低匹兹堡睡眠质量指数(PSQI)评分(MD=-3.54,95%CI:-4.31~-2.78,P<0.01)、降低6个月内复发率(RR=0.19,95%CI:0.10~0.37,P<0.01)。但在改善治疗后睡眠时间6 h以上患者的比率方面,差异无统计学意义(RR=1.31,95%CI:0.97~1.76,P=0.078)。传统SGB疗法存在一定不良风险,超声下SGB疗法更为安全。试验序贯分析显示,有效率的累积样本量跨过了传统界值和试验序贯分析界值,虽未达到期望信息样本量,但已提前获得肯定结果。睡眠潜伏期、PSQI和6个月内复发率的GRADE评价证据质量为中级,其余均为低级。结论 SGB相较于常规西药治疗失眠,在提高总有效率、治疗后睡眠时间3 h以上患者的比率、总睡眠时间,缩短睡眠潜伏期、改善PSQI评分和6个月内复发率方面获得一定证据支持;在改善治疗后睡眠时间6 h以上患者的比率方面,二者疗效相当。虽然结果稳定可靠,但目前证据级别较低,有待开展大样本随机对照试验以提高其临床疗效的循证支持。 展开更多
关键词 星状神经节阻滞 失眠 META分析 试验序贯分析 GRADE分级
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基于“脾不散精,痰瘀互结”理论组方联合西药治疗冠心病疗效及降TG水平的Meta分析与试验序贯分析
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作者 肖志强 张鑫俊 顾宁 《世界科学技术-中医药现代化》 北大核心 2025年第5期1312-1325,共14页
目的分析“脾不散精,痰瘀互结”理论组方联合西药治疗冠心病的有效性和安全性及对血脂异常患者TG水平的影响。方法检索8个数据库建库至2024年11月收录的基于“脾不散精,痰瘀互结”理论组方治疗冠心病合并血脂异常的随机对照试验(Randomi... 目的分析“脾不散精,痰瘀互结”理论组方联合西药治疗冠心病的有效性和安全性及对血脂异常患者TG水平的影响。方法检索8个数据库建库至2024年11月收录的基于“脾不散精,痰瘀互结”理论组方治疗冠心病合并血脂异常的随机对照试验(Randomized controlled trials,RCTs),根据纳排标准,对文献进行筛选、数据提取。采用RevMan5.4进行Meta分析,TSA 0.9.5.10 Beta软件开展试验序贯分析,GRADE系统评价各结局指标的证据质量。结果共纳入30篇RCTs,样本量2798例,其中试验组1402例,对照组1396例。Meta分析显示,化痰祛瘀法组相较于对照组能有效提高临床疗效(RR=1.26,95%CI[1.19,1.33],P<0.00001)、心绞痛疗效(RR=1.25,95%CI[1.14,1.37],P<0.00001)、心电图疗效(RR=1.27,95%CI[1.17,1.39],P<0.00001)以及中医症状疗效(RR=1.32,95%CI[1.23,1.42],P<0.00001),并降低TG水平(WMD=-0.44,95%CI[-0.52,-0.36],P<0.00001)及hs-CRP水平(WMD=-2.80,95%CI[-3.15,-2.45],P<0.00001)。在血液流变学方面,化痰祛瘀法同样展现出显著效果,能有效降低WBV(WMD=-1.34,95%CI[-1.65,-1.02],P<0.00001)、PV水平(WMD=-0.44,95%CI[-0.45,-0.43],P<0.00001)以及FIB水平(WMD=-0.46,95%CI[-0.75,-0.18],P=0.001)。安全性方面,19项RCTs报道了不良反应,但病情普遍较轻,且治疗后症状消失。TSA显示,临床疗效的累积Z曲线穿过了传统界值和TSA界值,进一步肯定临床疗效。GRADE证据质量评价显示,上述结局指标的证据等级为中或低级。结论基于“脾不散精,痰瘀互结”理论组方的中药在治疗冠心病及降血脂异常患者TG水平上是有效且安全的,但因纳入研究的质量局限性,仍需设计更为严谨、更大规模的RCTs加以验证。 展开更多
关键词 冠心病 高甘油三脂血症 脾不散精 痰瘀互结 Meta分析 试验序贯分析 GRADE证据分级
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Graded density impactor design via machine learning and numerical simulation:Achieve controllable stress and strain rate 被引量:1
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作者 Yahui Huang Ruizhi Zhang +6 位作者 Shuaixiong Liu Jian Peng Yong Liu Han Chen Jian Zhang Guoqiang Luo Qiang Shen 《Defence Technology(防务技术)》 2025年第9期262-273,共12页
The graded density impactor(GDI)dynamic loading technique is crucial for acquiring the dynamic physical property parameters of materials used in weapons.The accuracy and timeliness of GDI structural design are key to ... The graded density impactor(GDI)dynamic loading technique is crucial for acquiring the dynamic physical property parameters of materials used in weapons.The accuracy and timeliness of GDI structural design are key to achieving controllable stress-strain rate loading.In this study,we have,for the first time,combined one-dimensional fluid computational software with machine learning methods.We first elucidated the mechanisms by which GDI structures control stress and strain rates.Subsequently,we constructed a machine learning model to create a structure-property response surface.The results show that altering the loading velocity and interlayer thickness has a pronounced regulatory effect on stress and strain rates.In contrast,the impedance distribution index and target thickness have less significant effects on stress regulation,although there is a matching relationship between target thickness and interlayer thickness.Compared with traditional design methods,the machine learning approach offers a10^(4)—10^(5)times increase in efficiency and the potential to achieve a global optimum,holding promise for guiding the design of GDI. 展开更多
关键词 Machine learning Numerical simulation Graded density impactor Controllable stress-strain rate loading Response surface methodology
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Effectiveness analysis of corona protection materials for HV rotating machines
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作者 Victor Belko FENG Shengxi +2 位作者 Efrem Feklistov FENG Yu LIU Ji 《电机与控制学报》 北大核心 2025年第4期35-44,共10页
In this paper a fully parametrized finite element simulation model of the stator bar end is created using the COMSOL Multiphysics.The model allows conducting the comparison of different corona protection structures’d... In this paper a fully parametrized finite element simulation model of the stator bar end is created using the COMSOL Multiphysics.The model allows conducting the comparison of different corona protection structures’design,various materials properties,and finally optimizing the corona protection system.Several samples of SiC based nonlinear conductivity materials for corona protection were fabricated in laboratory and then investigated.The conductivity dependencies on electric field(0.05 to 1 kV/mm)and temperature(20 to 155℃)were measured.By comparing the heat-resistant grades of the corona protection material and the insulating material,the maximum working temperature of the corona protection material corresponds to the heat-resistant grade F of the insulating material.As the temperature increases,the nonlinear characteristics of the corona protection material in the experiment decrease dramatically,reducing the heat-resistant grade of the corona protection material.The decrease in the nonlinear characteristics of the corona protection material at the maximum operating temperature causes the maximum electric field strength at the end of the HV rotating machines end corona protection(ECP)exceeding the corona discharge electric field strength,resulting in corona phenomenon. 展开更多
关键词 stator windings partial discharges stress grading corona protection semiconductive materials surface resistance nonlinear properties
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Investigation of the ignition and combustion characteristics of Al@AP incorporated with graded aluminum powder
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作者 Su-Lan Yang Jing Wang +4 位作者 Zhi-Yu Zhang Kan Xie Ming-Hui Yu Yue-Ke Xiong Bin Tian 《Defence Technology(防务技术)》 2025年第8期225-235,共11页
The utilization of graded Al powders offers the possibility to adjust the combustion performance of Al powders,while simultaneously safeguarding their energy properties.In this paper,a series of graded Al powder have ... The utilization of graded Al powders offers the possibility to adjust the combustion performance of Al powders,while simultaneously safeguarding their energy properties.In this paper,a series of graded Al powder have been incorporated into the typical Al@AP composites through the spray drying technique.The thermal behavior,ignition and combustion characteristics were comprehensively evaluated and compared.The experimental results showed that with the varying inclusion of the graded Al,the heat of reaction exhibited a significant change,ranging from 9090 J·g^(-1) to 11036 J·g^(-1),which was strongly dependent on the particle size of Al.The combination of Al with diverse range of particle sizes in graded configuration serves to significantly enhance the decomposition of AP,resulting in the disappearance of the LTD stage and a conspicuous decrease of at least 11.7℃ in the peak temperature of the HTD.Furthermore,the maximum burning rate achieved by the Al-3@AP composite was 33.6 mm·s^(-1),which was exactly twice as high as that of the graded Al-1@AP composite with the lowest burning rate.Diffraction peaks corresponding to unburned Al were detected in the condensed combustion products of Al-1@AP,and the combustion images clearly indicated an incomplete combustion tendency for this sample.In contrast,a well-designed gradation of Al powders,such as a combination of fine Al powders with a particle size below 5μm,has proven to be the most conducive to enhancing the combustion efficiency of the composites. 展开更多
关键词 Ignition performance Thermal reactivity Core-shell structure Graded Al
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High-thermal free vibration analysis of functionally graded microplates using a new finite element formulation based on TSDT and MSCT
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作者 Huu Trong Dang Nhan Thinh Hoang +2 位作者 Quoc Hoa Pham Trung Thanh Tran Huy Gia Luong 《Defence Technology(防务技术)》 2025年第2期131-149,共19页
Recent advancements in additive manufacturing(AM)have revolutionized the design and production of complex engineering microstructures.Despite these advancements,their mathematical modeling and computational analysis r... Recent advancements in additive manufacturing(AM)have revolutionized the design and production of complex engineering microstructures.Despite these advancements,their mathematical modeling and computational analysis remain significant challenges.This research aims to develop an effective computational method for analyzing the free vibration of functionally graded(FG)microplates under high temperatures while resting on a Pasternak foundation(PF).This formulation leverages a new thirdorder shear deformation theory(new TSDT)for improved accuracy without requiring shear correction factors.Additionally,the modified couple stress theory(MCST)is incorporated to account for sizedependent effects in microplates.The PF is characterized by two parameters including spring stiffness(k_(w))and shear layer stiffness(k_(s)).To validate the proposed method,the results obtained are compared with those of the existing literature.Furthermore,numerical examples explore the influence of various factors on the high-temperature free vibration of FG microplates.These factors include the length scale parameter(l),geometric dimensions,material properties,and the presence of the elastic foundation.The findings significantly enhance our comprehension of the free vibration of FG microplates in high thermal environments.In addition,the findings significantly enhance our comprehension of the free vibration of FG microplates in high thermal environments.In addition,the results of this research will have great potential in military and defense applications such as components of submarines,fighter aircraft,and missiles. 展开更多
关键词 Microplates Functionally graded material Finite element method Modified couple stress theory New TSDT High-thermal free vibration Pasternak foundation
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An isogeometric approach for vibration characteristics analysis of functionally graded triply periodic minimal sandwich curved-doubly shell integrated with magneto-electro surface layers subjected to lowvelocity impact load
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作者 Le Hoai Pham Hoang Tu +1 位作者 Van Ke Tran Nguyen Thi Hue 《Defence Technology(防务技术)》 2025年第8期101-125,共25页
In this paper,the isogeometric analysis(IGA)method is employed to analyze the oscillation characteristics of functionally graded triply periodic minimal surface(FG-TPMS)curved-doubly shells integrated with magneto-ele... In this paper,the isogeometric analysis(IGA)method is employed to analyze the oscillation characteristics of functionally graded triply periodic minimal surface(FG-TPMS)curved-doubly shells integrated with magneto-electric surface layers(referred to as"FG-TPMS-MEE curved-doubly shells")subjected to low-velocity impact loads.This study presents low-velocity impact load model based on a single springmass(S-M)approach.The FG-TPMS-MEE curved-doubly shells are covered with two magneto-electric surface layers,while the core layer consists of three types:I-graph and Wrapped Package-graph(IWP),Gyroid(G),and Primitive(P),with various graded functions.These types are notable for their exceptional stiffness-to-weight ratios,enabling a wide range of potential applications.The Maxwell equations and electromagnetic boundary conditions are applied to compute the change in electric potentials and magnetic potentials.The equilibrium equations of the shell are derived from a refined higher-order shear deformation theory(HSDT),and the transient responses of the FG-TPMS-MEE curveddoubly shells are subsequently determined using Newmark's direct integration method.These results have applications in structural vibration control and the analysis of structures subjected to impact or explosive loads.Furthermore,this study provides a theoretical prediction of the low-velocity impact load and magneto-electric-elastic effects on the free vibration and transient response of FG-TPMS-MEE curved-doubly shells. 展开更多
关键词 IGA approach Free vibration and transient response Magneto-electro-elastic curved-doubly shell Low-velocity impact load Functionally graded triply periodic minimal
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正确理解和应用低质量证据形成指南推荐意见 被引量:5
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作者 史乾灵 刘辉 +5 位作者 王子君 罗旭飞 王冰怡 杨楠 孟文勃 陈耀龙 《协和医学杂志》 CSCD 北大核心 2024年第3期676-685,共10页
推荐意见是临床实践指南的核心。基于低质量证据作出强推荐意见是当前国内外指南普遍存在的现象。医务人员认为缺乏高质量的证据就无法制订高质量的指南或仅可制订专家共识是典型的误解。本文以GRADE分级系统为切入点,阐述低质量证据的... 推荐意见是临床实践指南的核心。基于低质量证据作出强推荐意见是当前国内外指南普遍存在的现象。医务人员认为缺乏高质量的证据就无法制订高质量的指南或仅可制订专家共识是典型的误解。本文以GRADE分级系统为切入点,阐述低质量证据的基本内涵和临床作用,介绍基于低质量证据形成指南推荐意见的方法,以期为我国指南制订者和使用者提供参考。 展开更多
关键词 临床实践指南 推荐意见 证据质量 GRADE
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刮痧改善腰椎间盘突出疼痛症状的系统评价及GRADE证据质量评价 被引量:1
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作者 高玉洁 王佳怡 +4 位作者 葛浩天 徐桂华 杨敏 姜荣荣 陈华 《世界科学技术-中医药现代化》 CSCD 北大核心 2024年第2期419-428,共10页
目的系统评价刮痧干预腰椎间盘突出疼痛症状的疗效与安全性,为其临床治疗提供循证依据。方法计算机检索自建库到2022年8月29日前公开发表在中国知网、万方、维普、中国生物医学文献服务系统、PubMed、Embase、Web of Science、The Cochr... 目的系统评价刮痧干预腰椎间盘突出疼痛症状的疗效与安全性,为其临床治疗提供循证依据。方法计算机检索自建库到2022年8月29日前公开发表在中国知网、万方、维普、中国生物医学文献服务系统、PubMed、Embase、Web of Science、The Cochrane Library数据库,收集关于刮痧干预腰椎间盘突出的随机对照试验(Randomized controlled trial,RCT)。文章由两名研究者独立筛选,根据Cochrane Reviewers Handbook 6.2的偏倚风险评估工具对纳入文献进行质量评价,应用RevMan 5.4软件对纳入文献的结局指标进行Meta分析,并采用GRADE系统对结局指标进行证据质量等级评价。结果最终纳入10篇RCT,共1087例患者。Meta分析结果显示:刮痧试验组治疗腰椎间盘突出患者在疼痛VAS评分[MD=-1.11,95%CI(-1.58,-0.64),P<0.00001]、日本骨科协会(JOA)评分[MD=4.47,95%CI(3.76,5.17),P<0.00001]、临床有效率[relative risk(RR)=1.13,95%CI(1.08,1.19),P<0.00001]和护理满意度[RR=1.21,95%CI(1.09,1.34),P=0.0005]方面,明显优于对照组,差异均有统计学意义(P<0.00001)。本文结局指标的证据质量为极低。结论当前证据表明,刮痧治疗腰椎间盘突出患者的疼痛症状具有良好临床疗效,并有助于提高临床护理满意度。由于部分结局证据质量较低,有待严谨的多中心、大样本随机对照试验来进一步验证其有效性,提升临床证据。 展开更多
关键词 刮痧 腰椎间盘突出 系统评价 META分析 GRADE
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参芪扶正注射液辅助治疗慢性阻塞性肺疾病的Meta分析与GRADE评价 被引量:1
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作者 黄武祯 陈斯宁 +4 位作者 黎展华 黄海月 张莞芬 黄丹炫 蒙建华 《科学技术与工程》 北大核心 2024年第29期12479-12487,共9页
为了系统评价参芪扶正注射液联合常规治疗作为干预措施对慢性阻塞性肺疾病(chronic obstructive pulmonary disease,COPD)患者的临床疗效和安全性。检索中国国家知识基础设施(China national knowledge infrastructure,CNKI)、PubMed、... 为了系统评价参芪扶正注射液联合常规治疗作为干预措施对慢性阻塞性肺疾病(chronic obstructive pulmonary disease,COPD)患者的临床疗效和安全性。检索中国国家知识基础设施(China national knowledge infrastructure,CNKI)、PubMed、万方数据知识服务平台(Wanfang Data)、维普中文科技期刊数据库(Weipu China science and technology journal database,VIP)等数据库,筛选并纳入2023年6月18日以前发表的参芪扶正注射液联合常规疗法治疗COPD患者的随机对照试验(randomized controlled trials,RCT),采用Cochrane风险评价工具及评估、发展和评价建议分级(grading of recommendations assessment,development and evaluation,GRADE)系统进行文献证据质量评价,用RevMan 5.4软件对临床疗效及安全性指标进行Meta分析。结果表明,共纳入16项RCTs,1 486例患者。Meta分析结果显示,参芪扶正注射液辅助治疗可提高患者总有效率和第1秒用力呼气容积/用力肺活量比值(forced expiratory volume in one second/forced vital capacity,FEV1/FVC)指标,与对照组相比具有优势(P<0.000 01、P<0.000 1);不良反应少,无严重不良反应(adverse drug reactions,ADR),两组对比无统计学差异(P=0.32);GRADE评价结果显示,有效率及不良反应指标的证据质量均为中等级,肺功能为低等级。可见参芪扶正注射辅助治疗COPD可以提高患者临床疗效,改善肺功能,且具有良好的安全性。但所纳入研究具有局限性,证据质量不高,仍需结合中药辨证使用特点,规范实验方案,开展更多的高质量RCT研究。 展开更多
关键词 参芪扶正注射 慢性阻塞性肺疾病 随机对照试验 META分析 GRADE评价
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复方金钱草颗粒临床应用专家共识
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作者 苏鑫鑫 高瞻 +5 位作者 席俊羽 刘亚芬 丁家森 黎元元 谢雁鸣 Representative Writing and Formuating Group 《中华中医药学刊》 CAS 北大核心 2024年第6期252-258,共7页
复方金钱草颗粒为国家医保目录乙类中成药,在临床上广泛应用于泌尿系结石和尿路感染,经过长期的临床治疗经验,基于问卷调查、专家访谈及研究文献系统分析的基础上,认为复方金钱草颗粒对泌尿系结石和尿路感染疾病有良好的临床疗效,为指... 复方金钱草颗粒为国家医保目录乙类中成药,在临床上广泛应用于泌尿系结石和尿路感染,经过长期的临床治疗经验,基于问卷调查、专家访谈及研究文献系统分析的基础上,认为复方金钱草颗粒对泌尿系结石和尿路感染疾病有良好的临床疗效,为指南推荐用药。本共识严格遵循中成药临床应用专家共识步骤进行研制,针对泌尿系结石和尿路感染的治疗而制定;采用调查问卷的形式,调查有临床经验的医生,通过对循证医学证据进行综合分析,并采用名义组法原则,汇总分析结果为24条推荐意见和共识建议。进一步明确复方金钱草颗粒治疗泌尿系结石和尿路感染的适应症、用法用药、疗程、介入时间、联合用药等,说明了临床应用的安全性,并分别进行30以上的专家组进行了征求意见和同行评议。本共识旨在指导临床正确使用复方金钱草颗粒治疗泌尿系结石和尿路感染。 展开更多
关键词 复方金钱草颗粒 泌尿系结石 尿路感染 专家共识 GRADE
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腕踝针干预术后疼痛疗效的Meta分析和Grade评价 被引量:5
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作者 于明珠 赵丹娜 +3 位作者 杨艾影 喻悦 李鑫滟 朱宇 《军事护理》 CSCD 北大核心 2024年第5期101-106,114,共7页
目的运用循证医学方法对腕踝针干预术后疼痛的疗效和安全性进行系统评价和Grade评价。方法计算机检索中国知网、万方、维普、中国生物医学文献数据库、PubMed、Embase、Web of Science、Cochrane Library中关于腕踝针干预术后疼痛的随... 目的运用循证医学方法对腕踝针干预术后疼痛的疗效和安全性进行系统评价和Grade评价。方法计算机检索中国知网、万方、维普、中国生物医学文献数据库、PubMed、Embase、Web of Science、Cochrane Library中关于腕踝针干预术后疼痛的随机对照试验,检索时限为建库至2023年10月。采用RevMan 5.4软件进行Meta分析。结果纳入23篇文献,共计1968例患者,Meta分析结果显示,与常规治疗相比,腕踝针能够提高术后疼痛患者的总有效率[OR=4.42,95%CI(2.60,7.50),P<0.001],术后镇痛泵药量使用减少[MD=-9.03,95%CI(-12.09,-5.98),P<0.001],术后疼痛评分降低[MD=-1.39,95%CI(-1.68,-1.09),P<0.001],可减少不良反应发生率[RR=0.40,95%CI(0.32,0.48),P<0.001]以及临床满意度[OR=3.94,95%CI(2.40,6.48),P<0.001]。Grade证据分级结果显示:总有效率、不良反应发生率和临床满意度3项结局指标为中等质量证据,VAS评分指标为低质量证据,镇痛泵药量使用指标为极低质量证据。结论腕踝针可提高总有效率,减少术后镇痛药用量,不良反应少,安全性高,为患者提供了一种安全有效的镇痛方式。 展开更多
关键词 腕踝针 术后疼痛 META分析 Grade评价
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公共卫生决策证据质量的Meta流行病学研究
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作者 黄家艺 邓欣欣 +5 位作者 王汉彬 胡晓晔 梁翠 崔璐 杨克虎 李秀霞 《中国卫生政策研究》 CSCD 北大核心 2024年第10期76-81,共6页
目的:比较公共卫生决策证据质量评价体系(PHE-Grading)与推荐分级的评价、制定与评估体系(GRADE)在评价公共卫生决策证据质量方面的差异性。方法:计算机检索Cochrane Library数据库,获取建库起至2024年2月27日发表的有关“Public healt... 目的:比较公共卫生决策证据质量评价体系(PHE-Grading)与推荐分级的评价、制定与评估体系(GRADE)在评价公共卫生决策证据质量方面的差异性。方法:计算机检索Cochrane Library数据库,获取建库起至2024年2月27日发表的有关“Public health”主题的系统评价。采用EndNote 20软件进行文献筛选,Excel 2021和SPSS 22.0软件进行数据整理和分析,使用RevMan 5.4.1软件绘制森林图。结果:最终纳入61篇系统评价进行证据质量评价。GRADE和PHE-Grading证据分级结果的森林图显示,证据等级为高[OR:2.39,95%CI(1.21,4.75)]、中[OR:0.40,95%CI(0.31,0.52)]、低[OR:0.37,95%CI(0.29,0.46)]和极低[OR:85.11,95%CI(34.80,208.11)],证据质量分级结果的差异有统计学意义。结论:与GRADE相比,PHE-Grading对公共卫生决策证据确信度的把握可能更为精准,目前公共卫生决策证据质量仍集中在中低水平,仍需加强高质量研究以支持科学决策。 展开更多
关键词 公共卫生 决策 证据质量 GRADE方法 PHE-Grading
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Exact solution for thermal vibration of multi-directional functionally graded porous plates submerged in fluid medium 被引量:1
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作者 Quoc-Hoa Pham Van Ke Tran Phu-Cuong Nguyen 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2024年第5期77-99,共23页
An analytical method for analyzing the thermal vibration of multi-directional functionally graded porous rectangular plates in fluid media with novel porosity patterns is developed in this study.Mechanical properties ... An analytical method for analyzing the thermal vibration of multi-directional functionally graded porous rectangular plates in fluid media with novel porosity patterns is developed in this study.Mechanical properties of MFG porous plates change according to the length,width,and thickness directions for various materials and the porosity distribution which can be widely applied in many fields of engineering and defence technology.Especially,new porous rules that depend on spatial coordinates and grading indexes are proposed in the present work.Applying Hamilton's principle and the refined higher-order shear deformation plate theory,the governing equation of motion of an MFG porous rectangular plate in a fluid medium(the fluid-plate system)is obtained.The fluid velocity potential is derived from the boundary conditions of the fluid-plate system and is used to compute the extra mass.The GalerkinVlasov solution is used to solve and give natural frequencies of MFG porous plates with various boundary conditions in a fluid medium.The validity and reliability of the suggested method are confirmed by comparing numerical results of the present work with those from available works in the literature.The effects of different parameters on the thermal vibration response of MFG porous rectangular plates are studied in detail.These findings demonstrate that the behavior of the structure within a liquid medium differs significantly from that within a vacuum medium.Thereby,they offer appropriate operational approaches for the structure when employed in various mediums. 展开更多
关键词 Plate-fluid contact Galerkin Vlasov's method Multi-directional functionally graded plate Novel porosity Thermal vibration Refined higher-order shear deformation theory
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Characterization of fluidized reduction roasting of nickel laterite ore under CO/CO_(2)atmosphere
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作者 ZHENG Si-qi ZHANG Hai-xia +2 位作者 WANG Xiao-fang HU Hui ZHU Zhi-ping 《Journal of Central South University》 SCIE EI CAS CSCD 2024年第9期3068-3078,共11页
Fluidized reduction roasting is an efficient metallurgical technique.However,its application to nickel laterite ore has rarely been reported.In this paper,the effects of reduction temperature,reduction time,CO concent... Fluidized reduction roasting is an efficient metallurgical technique.However,its application to nickel laterite ore has rarely been reported.In this paper,the effects of reduction temperature,reduction time,CO concentration,and material particle size on the roasting characteristics of ferronickel fluidization reduction were investigated.Combined with X-ray diffraction,scanning electron microscopy-energy dispersive spectrometry(SEM-EDS)characterization,the mineral phases and microscopic morphology of nickel laterite ore and its roasted ores were analyzed in depth.The results indicated that under the condition of a CO/CO_(2)ratio of 1:1,a reduction temperature of 800℃,and a reduction roasting time of 60 min,a nickel-iron concentrate with a nickel grade of 2.10%and an iron content of 45.96%was produced from a raw material with a nickel grade of 1.45%,achieving a remarkable nickel recovery rate of 46.26%.XRD and SEM-EDS analysis indicated that nickel in the concentrate mainly exists in the form of[Fe,Ni],while the unrecovered nickel in the tailings is primarily present in the form of[Fe,Ni]and Ni_(2)SiO_(4)in forsterite.This study established a theoretical foundation for further exploration of fluidized reduction roasting technology. 展开更多
关键词 nickel laterite ore fluidized reduction roasting nickel grade RECOVERY
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Evolution of microstructure and mechanical properties in multi-layer 316L-TiC composite fabricated by selective laser melting additive manufacturing
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作者 Sasan YAZDANI Suleyman TEKELI +2 位作者 Hossein RABIEIFAR Ufuk TASCI Elina AKBARZADEH 《Journal of Central South University》 SCIE EI CAS CSCD 2024年第9期2973-2991,共19页
In this study,the microstructure and mechanical properties of a multi-layered 316L-TiC composite material produced by selective laser melting(SLM)additive manufacturing process are investigated.Three different layers,... In this study,the microstructure and mechanical properties of a multi-layered 316L-TiC composite material produced by selective laser melting(SLM)additive manufacturing process are investigated.Three different layers,consisting of 316L stainless steel,316L-5 wt%TiC and 316L-10 wt%TiC,were additively manufactured.The microstructure of these layers was characterized by optical microscopy(OM)and scanning electron microscopy(SEM).X-ray diffraction(XRD)was used for phase analysis,and the mechanical properties were evaluated by tensile and nanoindentation tests.The microstructural observations show epitaxial grain growth within the composite layers,with the elongated grains growing predominantly in the build direction.XRD analysis confirms the successful incorporation of the TiC particles into the 316L matrix,with no unwanted phases present.Nanoindentation results indicate a significant increase in the hardness and modulus of elasticity of the composite layers compared to pure 316L stainless steel,suggesting improved mechanical properties.Tensile tests show remarkable strength values for the 316L-TiC composite samples,which can be attributed to the embedded TiC particles.These results highlight the potential of SLM in the production of multi-layer metal-ceramic composites for applications that require high strength and ductility of metallic components in addition to the exceptional hardness of the ceramic particles. 展开更多
关键词 multilayer metal-ceramic composites selective laser melting functionally graded materials 316 L stainless steel TIC
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Time-dependent effects in transient liquid phase bonding of 304L and Cp-Ti using an Ag-Cu interlayer
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作者 Saeed VAZIRIAN Mohammad MOSHKBAR BAKHSHAYESH Ali FARZADI 《Journal of Central South University》 SCIE EI CAS CSCD 2024年第7期2237-2255,共19页
One of the challenges for bimetal manufacturing is the joining process.Hence,transient liquid phase(TLP)bonding was performed between 304L stainless steel and Cp-Ti using an Ag-Cu interlayer with a thickness of 75μm ... One of the challenges for bimetal manufacturing is the joining process.Hence,transient liquid phase(TLP)bonding was performed between 304L stainless steel and Cp-Ti using an Ag-Cu interlayer with a thickness of 75μm for bonding time of 20,40,60,and 90 min.The bonding temperature of 860℃ was considered,which is under the β transus temperature of Cp-Ti.During TLP bonding,various intermetallic compounds(IMCs),including Ti_(5)Cr_(7)Fe_(17),(Cr,Fe)_(2)Ti,Ti(Cu,Fe),Ti_(2)(Cu,Ag),and Ti_(2)Cu from 304L toward Cp-Ti formed in the joint.Also,on the one side,with the increase in time,further diffusion of elements decreases the blocky IMCs such as Ti_(5)Cr_(7)Fe_(17),(Cr,Fe)_(2)Ti,Ti(Cu,Fe)in the 304L diffusion-affected zone(DAZ)and reaction zone,and on the other side,Ti_(2)(Cu,Ag)IMC transformed into fine morphology toward Cp-Ti DAZ.The microhardness test also demonstrated that the(Cr,Fe)_(2)Ti+Ti_(5)Cr_(7)Fe_(17) IMCs in the DAZ on the side of 304L have a hardness value of HV 564,making it the hardest phase.The maximum and minimum shear strength values are equal to 78.84 and 29.0 MPa,respectively.The cleavage pattern dominated fracture surfaces due to the formation of brittle phases in dissimilar joints. 展开更多
关键词 diffusion brazing transient liquid phase bonding dissimilar material joints microstructural evolution mechanical properties grade 2 titanium
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