期刊文献+
共找到1,017篇文章
< 1 2 51 >
每页显示 20 50 100
Heat balance of solar-soil source heat pump compound system 被引量:3
1
作者 陈金华 包修碧 +1 位作者 彭运林 贾宇 《Journal of Central South University》 SCIE EI CAS 2012年第3期809-815,共7页
Based on the state-of-the-art studies of solar-soil source heat pump compound system, operation patterns of solar-soil compound system were analyzed, particularly the advantages of parallel operation pattern. It is fo... Based on the state-of-the-art studies of solar-soil source heat pump compound system, operation patterns of solar-soil compound system were analyzed, particularly the advantages of parallel operation pattern. It is found that parallel operation pattern is better for solar-soil compound system. Furthermore, the heat balance issue of solar-soil compound system was emphatically analyzed from four aspects, which were annual analysis of heating and cooling load, the heat exchange of ground heat exchanger, capacity determination of solar-assisted heat sottrce and heat balance calculation of solar-soil compound system. Moreover, annual rate of heat balance in a solar-soil source heat pump compound system was calculated with a case study. It is shown that the annual heat unbalance ratio is 19%, which is less than 20%. As a result, the practical solar-soil compound system can basically maintain the heat balance of soil. 展开更多
关键词 solar-soil source heat pump compound system heat balance ground-coupled heat pump
在线阅读 下载PDF
Compound control for speed and tension multivariable coupling system of reversible cold strip mill 被引量:3
2
作者 方一鸣 刘乐 +1 位作者 李建雄 常茹 《Journal of Central South University》 SCIE EI CAS CSCD 2015年第2期529-538,共10页
To weaken the nonlinear coupling influence among the variables in the speed and tension system of reversible cold strip mill, a compound control(CC) strategy based on invariance principle was proposed. Firstly, invari... To weaken the nonlinear coupling influence among the variables in the speed and tension system of reversible cold strip mill, a compound control(CC) strategy based on invariance principle was proposed. Firstly, invariance principle was used to realize static decoupling between the speed and tension of reversible cold strip mill. Then, considering the influence caused by the time variation of steel coil radius and rotational inertia of the left and right coilers, as well as the uncertainties, a CC strategy that is composed of extended state observer(ESO) and global sliding mode control(GSMC) with backstepping adaptive was proposed,which further realized dynamic decoupling and coordination control for the speed and tension system. Theoretical analysis shows that the resulting closed-loop system is global bounded stable. Finally, the simulation was carried out on the speed and tension system of a 1422 mm reversible cold strip mill by using the actual data, and through the comparison of the other control strategies, validity of the proposed CC strategy was shown by the results. 展开更多
关键词 reversible cold strip mill speed and tension system decoupling invariance principle compound control extended state observer global sliding mode control
在线阅读 下载PDF
Persymmetric adaptive polarimetric detection of subspace range-spread targets in compound Gaussian sea clutter 被引量:2
3
作者 XU Shuwen HAO Yifan +1 位作者 WANG Zhuo XUE Jian 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2024年第1期31-42,共12页
This paper focuses on the adaptive detection of range and Doppler dual-spread targets in non-homogeneous and nonGaussian sea clutter.The sea clutter from two polarimetric channels is modeled as a compound-Gaussian mod... This paper focuses on the adaptive detection of range and Doppler dual-spread targets in non-homogeneous and nonGaussian sea clutter.The sea clutter from two polarimetric channels is modeled as a compound-Gaussian model with different parameters,and the target is modeled as a subspace rangespread target model.The persymmetric structure is used to model the clutter covariance matrix,in order to reduce the reliance on secondary data of the designed detectors.Three adaptive polarimetric persymmetric detectors are designed based on the generalized likelihood ratio test(GLRT),Rao test,and Wald test.All the proposed detectors have constant falsealarm rate property with respect to the clutter texture,the speckle covariance matrix.Experimental results on simulated and measured data show that three adaptive detectors outperform the competitors in different clutter environments,and the proposed GLRT detector has the best detection performance under different parameters. 展开更多
关键词 sea clutter adaptive polarimetric detection compound Gaussian model subspace range-spread target persymmetric structure
在线阅读 下载PDF
Performance analysis on solar-water compound source heat pump for radiant floor heating system
4
作者 曲世林 马飞 仇安兵 《Journal of Central South University》 SCIE EI CAS 2009年第S1期249-254,共6页
A solar-water compound source heat pump for radiant floor heating (SWHP-RFH) experimental system was introduced and analyzed. The SWHP-RFH system mainly consists of 11.44 m2 vacuum tube solar collector,1 000 L water t... A solar-water compound source heat pump for radiant floor heating (SWHP-RFH) experimental system was introduced and analyzed. The SWHP-RFH system mainly consists of 11.44 m2 vacuum tube solar collector,1 000 L water tank assisted 3 kW electrical heater,a water source heat pump,the radiant floor heating system with cross-linked polyethylene (PE-X) of diameter 20 mm,temperature controller and solar testing system. The SWHP-RFH system was tested from December to February during the heating season in Beijing,China under different operation situations. The test parameters include the outdoor air temperature,solar radiation intensity,indoor air temperature,radiation floor average surface temperature,average surface temperature of the building envelope,the inlet and outlet temperatures of solar collector,the temperature of water tank,the heat medium temperatures of heat pump condenser side and evaporator side,and the power consumption includes the water source heat pump system,the solar source heat pump system,the auxiliary heater and the radiant floor heating systems etc. The experimental results were used to calculate the collector efficiency,heat pump dynamic coefficient of performance (COP),total energy consumption and seasonal heating performance during the heating season. The results indicate that the performance of the compound source heat pump system is better than that of the air source heat pump system. Furthermore,some methods are suggested to improve the thermal performance of each component and the whole SWHP-RFH system. 展开更多
关键词 heat PUMP SOLAR compound SOURCE COEFFICIENT of performance
在线阅读 下载PDF
Simulation calculation of solubility of insoluble compound M_mA_a in complex system
5
作者 杨天足 张杜超 吴江华 《Journal of Central South University》 SCIE EI CAS 2012年第4期892-896,共5页
A simulation calculation model for the solubility of insoluble compound MmAa in complex system was established.According to coordination equilibrium principle,relevant dissociation reaction,complexation reaction,self-... A simulation calculation model for the solubility of insoluble compound MmAa in complex system was established.According to coordination equilibrium principle,relevant dissociation reaction,complexation reaction,self-complexation reaction and protonation reaction during insoluble compound dissolving were considered and then the mass balance equations about solubility calculation were obtained.In the case analysis,the solubility of silver chloride in ammonia system was obtained by simulation calculation,and curved surface charts of thermodynamic equilibrium about the total concentration of silver ions,pH and concentration of ammonia ions were drawn correspondingly.The results show that under the conditions of room temperature and 6 mol/L ammonia concentration,the calculated solubility value of silver chloride(34 g/L) is close to the actual value(31 g/L),demonstrating that this model is suitable for solubility calculation of insoluble compound MmAa in the complex system. 展开更多
关键词 complex system insoluble compound SOLUBILITY calculation model
在线阅读 下载PDF
Simple identification approach for trace heteroatom-containing compounds in petroleum fraction by Automated Mass Spectral Deconvolution and Identification System
6
作者 Nagy E.MOUSTAFA Kout EI-Kloub Fars MAHMOUD 《色谱》 CAS CSCD 北大核心 2016年第9期925-932,共8页
Here we present a simple yet effective gas chromatography-mass spectrometry(GC-MS)identification approach for the detection of heteroatom-containing compounds(HACCs)in petroleum fractions.The MS/AMDIS(Automated Mass S... Here we present a simple yet effective gas chromatography-mass spectrometry(GC-MS)identification approach for the detection of heteroatom-containing compounds(HACCs)in petroleum fractions.The MS/AMDIS(Automated Mass Spectral Deconvolution and Identification System)program was used to identify parts per million(ppm)HACC concentrations in petroleum fractions in place of traditional techniques(extraction and standard injection).Polycyclic aromatic sulfur heterocycles(S-PAHs)were used as model compounds to confirm the validity of the AMDIS identifiers,which were compared with extracted results using the off-line X-calibur software.AMDIS was able to identify ppm concentrations of S-PAHs in oil condensate.There was good agreement between experimental and AMDIS identification results for S-PAHs in oil condensate.AMDIS was also used to detect nitrogen-containing compounds(NCCs)and alkylphenols in oil condensate.Our results confirmed the presence of 2-methylbenzothiazole,carbazole,and 2,4-ditertbutyl phenol.In a crude oil sample,AMDIS identification of m/z=191 biomarkers wa s consistent with empirical results.Therefore,AMDIS can help to reduce the number of experimental steps in identification protocols. 展开更多
关键词 Automated Mass Spectral Deconvolution and Identification system(AMDIS) heteroatom-containing compounds PETROLEUM identification
在线阅读 下载PDF
Systematically structural identification of nitric compounds in crude oil with chemometric resolution
7
作者 黄熠 张泰铭 +1 位作者 梁逸曾 崔卉 《Journal of Central South University of Technology》 2005年第3期300-305,共6页
Aimed at the problem of classification of non-hydrocarbons of crude oil, the theoretical standpoint that the polarity of a compound depends on the whole structure and composition of molecule instead of a kind of heter... Aimed at the problem of classification of non-hydrocarbons of crude oil, the theoretical standpoint that the polarity of a compound depends on the whole structure and composition of molecule instead of a kind of heteroatom or its functional group was presented. A method was established for the systematically structural identification of nitric compounds in crude oil. The pre-fractionation of a crude oil sample into 7 fractions was performed by di- adsorption column chromatography with neutral aluminum oxide and silica gel. Subsequently, the individual components were obtained by using capillary column gas chromatography, and the types of compounds were detected by a mass spectrometer. In combination with a chemometric resolution, the compounds of fraction were further identified. This method can relieve the difficulty of classical analysis in identifying those species with very low contents or without being completely separated. The structures of 168 nitric compounds in a crude oil sample were determined by this method. 展开更多
关键词 column chromatography chromatography-mass spectrometry chemometric resolution structural identification non-hydrocarbon compound crude oil NITRIC
在线阅读 下载PDF
Assessment of electrostatic discharge sensitivity of nitrogen-rich heterocyclic energetic compounds and their salts as high energy-density dangerous compounds:A study of structural variables
8
作者 Mohammad Hossein Keshavarz Sedigheh Heydari Bani +1 位作者 Reza Bakhtiari Seyyed Hesamodin Hosseini 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2024年第9期15-22,共8页
Nitrogen-rich heterocyclic energetic compounds(NRHECs)and their salts have witnessed widespread synthesis in recent years.The substantial energy-density content within these compounds can lead to potentially dangerous... Nitrogen-rich heterocyclic energetic compounds(NRHECs)and their salts have witnessed widespread synthesis in recent years.The substantial energy-density content within these compounds can lead to potentially dangerous explosive reactions when subjected to external stimuli such as electrical discharge.Therefore,developing a reliable model for predicting their electrostatic discharge sensitivity(ESD)becomes imperative.This study proposes a novel and straightforward model based on the presence of specific groups(-NH_(2) or-NH-,-N=N^(+)-O^(-)and-NNO_(2),-ONO_(2) or-NO_(2))under certain conditions to assess the ESD of NRHECs and their salts,employing interpretable structural parameters.Utilizing a comprehensive dataset comprising 54 ESD measurements of NRHECs and their salts,divided into 49/5 training/test sets,the model achieves promising results.The Root Mean Square Error(RMSE),Mean Absolute Error(MAE),and Maximum Error for the training set are reported as 0.16 J,0.12 J,and 0.5 J,respectively.Notably,the ratios RMSE(training)/RMSE(test),MAE(training)/MAE(test),and Max Error(training)/Max Error(test)are all greater than 1.0,indicating the robust predictive capabilities of the model.The presented model demonstrates its efficacy in providing a reliable assessment of ESD for the targeted NRHECs and their salts,without the need for intricate computer codes or expert involvement. 展开更多
关键词 Electrostatic discharge sensitivity Heterocyclic energetic compounds containing azole compound Interpretable structural parameter Safety
在线阅读 下载PDF
Ultrastructure of the compound eye of Longitarsus lewisii(Baly,1874)(Coleoptera,Chrysomelidae)
9
作者 LIANG Zu-Long ZHANG Tian-Hao +1 位作者 LI Wen-Jie GE Si-Qin 《环境昆虫学报》 CSCD 北大核心 2024年第6期1316-1325,共10页
In this study,the morphology and ultrastructure of the compound eye of L.lewisii were investigated using scanning electron microscopy(SEM),transmission electron microscopy(TEM),microcomputed tomography(μCT),and 3D re... In this study,the morphology and ultrastructure of the compound eye of L.lewisii were investigated using scanning electron microscopy(SEM),transmission electron microscopy(TEM),microcomputed tomography(μCT),and 3D reconstruction.The compound eye of L.lewisii was of the apposition type,with an average of 121.88±7.64 ommatidia in males and 119.00±4.71 ommatidia in females.Each ommatidium was composed of a biconvex cornea,an acone consisting of four cone cells,eight retinular cells along with the rhabdom,two primary pigment cells,and numerous secondary pigment cells.The open type of rhabdom in L.lewisii consists of six peripheral rhabdomeres contributed by the six peripheral retinular cells(R1~R6)and two vertically attached central rhabdomeres contributed by R7 and R8 respectively.The orientation of microvilli suggested a weak sensitivity to polarized light perception. 展开更多
关键词 ULTRASTRUCTURE compound eye Longitarsus lewisii leaf beetle 3D reconstruction
在线阅读 下载PDF
光电系统中的自归零复合轴稳瞄系统 被引量:1
10
作者 刘小强 牛帅旭 +5 位作者 杨修林 王虎 杨永安 张蕙菁 柳井莉 赵子淳 《兵工学报》 北大核心 2025年第1期346-353,共8页
针对传统复合轴稳瞄系统子轴运动范围较小、易积分饱和导致系统失效的问题,提出自归零复合轴稳瞄系统。在剖析传统复合轴稳瞄系统子轴易积分饱和致系统失效原由的基础上,提出主轴据强度函数随动子轴的自归零复合轴稳瞄系统,通过直观展... 针对传统复合轴稳瞄系统子轴运动范围较小、易积分饱和导致系统失效的问题,提出自归零复合轴稳瞄系统。在剖析传统复合轴稳瞄系统子轴易积分饱和致系统失效原由的基础上,提出主轴据强度函数随动子轴的自归零复合轴稳瞄系统,通过直观展示、理论分析及数学仿真软件仿真其在避免子轴积分饱和及增强系统抗扰特性方面的可行性及优势,并搭建试验平台开展试验验证。测试结果表明,在低频段,自归零复合轴稳瞄系统可在保证子轴扰动抑制能力的同时,大幅度增强系统的主轴扰动抑制能力,使主轴误差维持在较小值,避免子轴限位饱和。由此表明自归零复合轴稳瞄系统的可行性,及其在避免子轴限位饱和、维持系统稳定性方面的优势。 展开更多
关键词 光电系统 稳瞄系统 复合轴 自归零 快速反射镜
在线阅读 下载PDF
直线电机−钢丝绳复合提升系统异类多电机协同驱动控制策略
11
作者 鲍久圣 张磊 +4 位作者 庄吉庆 牛振勇 阴妍 刘同冈 刘帅 《煤炭学报》 北大核心 2025年第S1期631-644,共14页
随着浅部煤炭资源的日益枯竭与煤矿高效率集约化发展,矿井提升系统正逐步朝着超深井与大载荷方向发展,传统矿井提升系统难以解决提升深度增加、钢丝绳加长和负载加大导致的提升效能下降与可靠性降低的难题。基于直线电机垂直推进技术原... 随着浅部煤炭资源的日益枯竭与煤矿高效率集约化发展,矿井提升系统正逐步朝着超深井与大载荷方向发展,传统矿井提升系统难以解决提升深度增加、钢丝绳加长和负载加大导致的提升效能下降与可靠性降低的难题。基于直线电机垂直推进技术原理,设计了直线电机−钢丝绳复合提升系统,重点对复合提升系统的异类多电机协同驱动控制策略进行了仿真和试验研究。首先,基于煤矿领域目前最大的50 t载煤箕斗进行增量设计,对直线电机与钢丝绳复合提升系统进行了总体方案设计,包括直线电机的初次级结构布置和箕斗增载提升设计等;其次,选定永磁同步电机(PMSM)和永磁直线电机(PLMSM)2种驱动电机的控制策略,分别搭建了单电机闭环矢量控制和多PLMSM同步控制的仿真模型,并对多PLMSM同步控制性能进行了仿真分析;再次,提出了“T−v控制策略”和“F−ω控制策略”2种异类多电机协同驱动控制策略,分别搭建了2种控制策略下的复合提升系统机−电耦合动力学模型,并根据提升系统实际应用工况分别对2种协同控制策略下系统动态特性进行了仿真分析;最后,研制了直线电机−钢丝绳复合提升系统原理样机,通过开展实验室试验验证了旋转电机与直线电机协同控制策略的可行性和有效性。研究结果表明:直线电机−钢丝绳复合提升系统可在原有钢丝绳提升系统的基础上额外增加34%的载煤量,以满足煤矿高效提升需求;通过仿真试验与原理样机试验对比T−v控制策略和F−ω控制策略可得,在T−v控制策略下,PLMSM作为提升系统的速度控制对象,PMSM仅需恒定转矩,提升系统具有异类电机协同控制精度高、钢丝绳张力变化幅值小等优点;在F−ω控制策略下,PMSM作为提升系统的速度控制对象,虽然存在着异类电机速度同步误差大的不足,但多台PLMSM仅需提供恒定推力,可简化复合提升系统的控制结构,适合于协同控制精度要求不高的低成本场景使用。 展开更多
关键词 矿井提升机 永磁同步电机 永磁直线电机 复合提升 协同控制
在线阅读 下载PDF
基于微透镜阵列的仿生复眼彩色系统设计及硬件模型优化
12
作者 王玉坤 刘羽萱 徐淑卿 《液晶与显示》 北大核心 2025年第10期1482-1489,共8页
复眼视觉系统具有大视场、体积小和对运动敏感的特性,特别适合用于广域运动目标探测、识别和光学自主导航。本研究为了实现仿生复眼系统的RGB三通道彩色成像,进行了仿生复眼彩色成像系统光学仿真并研制了样机。该样机共包含16个子眼,单... 复眼视觉系统具有大视场、体积小和对运动敏感的特性,特别适合用于广域运动目标探测、识别和光学自主导航。本研究为了实现仿生复眼系统的RGB三通道彩色成像,进行了仿生复眼彩色成像系统光学仿真并研制了样机。该样机共包含16个子眼,单个子眼焦距为15 mm。基于该样机进行了仿生复眼彩色成像性能验证实验。实验结果表明,该系统的子眼视场为22.62°,总视场达85.02°,在60 cm距离处其分辨率达到6 lp/mm,且具有良好的成像对比度。此外,还进行了场景成像实验以验证其成像性能。结果表明,仿生复眼彩色成像系统可满足复杂环境下广域目标的探测、三维定位和识别等应用。 展开更多
关键词 复眼视觉系统 复眼彩色成像 复眼光学设计 子图像位置调整
在线阅读 下载PDF
北方农牧交错区乡村人地系统脆弱性演变机制与发展策略——以内蒙古达尔罕茂明安联合旗为例
13
作者 李文龙 徐芮 +1 位作者 侯梦晨 林海英 《地理科学》 北大核心 2025年第11期2481-2494,共14页
社会–生态系统脆弱性强调系统承受多重扰动冲击与通过社会经济与生态环境协调发展从而适应冲击能力的综合评估,为综合分析不确定条件下人类社会的可持续发展奠定基础。本研究将社会–生态系统脆弱性理论框架引入农牧复合型乡村人地系... 社会–生态系统脆弱性强调系统承受多重扰动冲击与通过社会经济与生态环境协调发展从而适应冲击能力的综合评估,为综合分析不确定条件下人类社会的可持续发展奠定基础。本研究将社会–生态系统脆弱性理论框架引入农牧复合型乡村人地系统多重扰动效应评估中,在明晰农牧复合型乡村人地系统脆弱性内涵的基础上,从压力程度、敏感状态和响应能力3个维度建立受多重扰动的系统评估体系,选取中国北方农牧交错区内蒙古达尔罕茂明安联合旗乡村为案例区,基于1990—2022年达茂旗乡村社会经济发展数据、气象数据、遥感影像解译数据,运用熵值法、变异系数法与障碍度模型对受多重扰动的乡村人地系统脆弱性演变过程、影响因素及作用路径进行总结。研究表明:①农牧复合型乡村人地系统对多重扰动的脆弱性出现急速下降、缓慢上升、缓慢下降的变化特征,脆弱性由高到低排序为:农业乡村、畜牧业乡村、旅游乡村、综合性乡村;②30 a来脆弱性差异度呈现小幅度增高、大幅度降低的波动式循环发展特征,农业乡村脆弱性低幅度变化,畜牧业乡村脆弱性变异幅度随纬度提高而降低,旅游与综合型乡村脆弱性高幅度变化;③脆弱性变化主要影响因素是农牧民人均收入、人均耕地面积、人均牲畜头数、年降水量,不同乡村脆弱性主要影响因素存在显著差异;④农牧复合型乡村人地系统的多重扰动源于气候暖干化与生态工程实施,系统状态深受多重扰动后其结构与功能变化的制约,系统响应变化主要受乡村社会、经济、生态发展方式与农牧户生计影响。最后从乡村经济、社会、管理、环境层面提出降低系统脆弱性的对策建议。 展开更多
关键词 农牧复合乡村 人地系统 系统脆弱性 农牧交错区
在线阅读 下载PDF
调适性动员:面向复合型灾害的基层社会动员逻辑
14
作者 贾玉娇 傅昱玮 《华中科技大学学报(社会科学版)》 北大核心 2025年第4期37-48,共12页
党政体制作为理解当代中国政治体制和国家治理的标识性概念,业已成为政治学、社会学和公共管理学等学科领域的热点议题。然而,既有研究疏于考察党政体制与社会系统的互动,而这一互动过程实质上已外化于基层社会动员的具体实践中,表征了... 党政体制作为理解当代中国政治体制和国家治理的标识性概念,业已成为政治学、社会学和公共管理学等学科领域的热点议题。然而,既有研究疏于考察党政体制与社会系统的互动,而这一互动过程实质上已外化于基层社会动员的具体实践中,表征了独特的中国国家治理范式。伴随复合型灾害的涌现及其不确定性的凸显,如何建构与这一特殊治理情境相契合的新的分析框架已成为国家治理的一项基本研究议题。这一议题立足于复合型灾害治理情境,着眼于深化和拓展党政体制的概念范畴,尝试建构一个更具包容性的分析框架,即“调适性动员”。该框架的理论逻辑在于:基于政治统合与地方性情境融合的合一,以消解不确定性催生的模糊治理边界,并实现社会治灾基础的整体性建构。其实践逻辑在于:通过校准治灾任务、重塑治灾组织、下沉治灾资源以化解应急态下常规制度失灵问题;通过党组织的嵌入与延伸、转译治灾政策、发动地方能人以激活常态下社会成员的治灾主体性。 展开更多
关键词 党政体制 社会动员 复合型灾害 不确定性 调适性动员
在线阅读 下载PDF
原人参二醇型皂苷活性代谢物Compound K药理活性的研究进展 被引量:20
15
作者 李相鹏 王鹏 李英霞 《中国药理学与毒理学杂志》 CAS CSCD 北大核心 2011年第1期97-101,共5页
人参皂苷Compound K〔20-O-β-D-葡萄糖基-20(S)-原人参二醇,CK〕是原人参二醇型人参皂苷在人体内主要吸收形式和药效实体。近年来,CK的药理活性研究又有了新进展:①CK可通过活化胱天蛋白酶8直接或通过线粒体途径间接地激活胱天蛋白酶3... 人参皂苷Compound K〔20-O-β-D-葡萄糖基-20(S)-原人参二醇,CK〕是原人参二醇型人参皂苷在人体内主要吸收形式和药效实体。近年来,CK的药理活性研究又有了新进展:①CK可通过活化胱天蛋白酶8直接或通过线粒体途径间接地激活胱天蛋白酶3,诱导肿瘤细胞凋亡;下调基质金属蛋白酶9基因的表达,抑制肿瘤细胞的转移;②可通过下调多种炎症因子如白细胞介素-4(IL-4),IL-6,肿瘤坏死因子α等及环氧合酶2与一氧化氮合酶的表达而发挥抗炎、抗过敏和神经保护作用;③可阻断ATP敏感性K+离子通道,促进胰岛素分泌,增强组织胰岛素敏感性,抑制糖异生,促进糖酵解,对胰岛素依赖性糖尿病表现出良好的疗效;④可上调核苷切除修复相关蛋白基因的表达,减少紫外线引起的DNA损伤,防止皮肤老化等。本文重点对近几年有关CK的药理活性及其作用机制研究新进展进行综述。 展开更多
关键词 原人参二醇皂苷 compound K 药理学活性
在线阅读 下载PDF
人参皂苷代谢产物Compound K抑制TNF-α诱导的人支气管上皮细胞分泌RANTES 被引量:11
16
作者 李群益 陈莉 +3 位作者 张留弟 王轶 钟明康 施孝金 《第二军医大学学报》 CAS CSCD 北大核心 2015年第7期722-726,共5页
目的探讨人参皂苷代谢产物Compound K(CK)对炎症因子TNF-α诱导的人支气管上皮细胞BEAS-2B分泌调节活化正常T细胞表达和分泌趋化因子(RANTES)的影响及其机制。方法 ELISA法测定CK对BEAS-2B细胞上清液中RANTES含量的影响;采用RT-PCR... 目的探讨人参皂苷代谢产物Compound K(CK)对炎症因子TNF-α诱导的人支气管上皮细胞BEAS-2B分泌调节活化正常T细胞表达和分泌趋化因子(RANTES)的影响及其机制。方法 ELISA法测定CK对BEAS-2B细胞上清液中RANTES含量的影响;采用RT-PCR和蛋白质免疫印迹技术检测RANTES mRNA及蛋白的表达情况;采用荧光素酶报告基因系统检测CK对活化蛋白转录因子1(activator protein 1,AP-1)和糖皮质激素受体(glucocorticoid receptor,GR)转录抑制或转录激活的影响;运用GR拮抗剂米非司酮,验证CK对RANTES的抑制效应是否由GR介导。结果 3~30μmol/L的CK抑制了TNF-α诱导的RANTES分泌、mRNA及蛋白水平;CK抑制AP-1的转录激活,在BEAS-2B细胞中激活GR信号通路;并且,CK通过GR抑制了BEAS-2B细胞分泌RANTES。结论 CK能够抑制炎症因子TNF-α诱导的支气管上皮细胞分泌RANTES,其机制可能与激活GR、抑制AP-1对下游靶基因的调控有关。 展开更多
关键词 糖皮质激素受体 人参皂苷类 compound K 炎症 趋化因子CCL5 细胞因子类 哮喘
在线阅读 下载PDF
反相高效液相色谱法测定人参皂甙Compound-K的含量 被引量:11
17
作者 周伟 罗振时 周珮 《色谱》 CAS CSCD 北大核心 2005年第3期270-272,共3页
人参皂甙compoundK(CK)在人参中的含量极低,但它是其他含量较高的人参皂甙Rb1和Rb2等在人体肠道内的主要降解产物和最终吸收形式,具有很高的生物活性。采用反相高效液相色谱法测定了人参总皂甙发酵液中CK的含量。色谱条件为:反相C18柱;... 人参皂甙compoundK(CK)在人参中的含量极低,但它是其他含量较高的人参皂甙Rb1和Rb2等在人体肠道内的主要降解产物和最终吸收形式,具有很高的生物活性。采用反相高效液相色谱法测定了人参总皂甙发酵液中CK的含量。色谱条件为:反相C18柱;乙腈水(体积比为48∶52)溶液为流动相,流速1.0mL/min;紫外检测波长203nm;柱温35℃;外标法定量。结果表明:CK的质量浓度为0.05~0.8g/L时,其峰面积与质量浓度具有良好的线性关系,相关系数为0.9998。方法的检测限(S/N=3)为2.5mg/L,峰面积测定值的相对标准偏差(n=6)为2.20%。测定栽培人参总皂甙及三七茎叶总皂甙微生物发酵液中CK的平均加标回收率(n=3)分别为98.6%和99.7%。该方法快速简便,准确可靠,可用于CK的制备研究及药物开发。 展开更多
关键词 高效液相色谱法 人参皂甙compound—K 人参 三七
在线阅读 下载PDF
施肥处理对林下菊苣生产和土壤特性的影响
18
作者 刘晓宇 毛培春 +5 位作者 丁建莉 郑明利 武凤霞 田小霞 郭玉霞 孟林 《草业科学》 北大核心 2025年第9期2332-2342,共11页
林下优质饲草丰产栽培是构建环境友好型林草禽复合生态种养模式的重要技术环节。本研究采用随机区组试验设计,在枫树(Acer palmatum)林下建植菊苣(Cichorium intybus)草地并设置2个氮磷钾复合肥梯度[270 kg·hm^(−2)(F_(1))和240 kg... 林下优质饲草丰产栽培是构建环境友好型林草禽复合生态种养模式的重要技术环节。本研究采用随机区组试验设计,在枫树(Acer palmatum)林下建植菊苣(Cichorium intybus)草地并设置2个氮磷钾复合肥梯度[270 kg·hm^(−2)(F_(1))和240 kg·hm^(−2)(F_(2))]配施2种农林废弃物发酵沤制的液体堆肥茶7 L·m^(−2)[香菇菌渣+鸡粪发酵液体堆肥茶(Y_(1))和香菇菌渣+鸡粪+农林枯枝落叶堆肥茶(Y_(2))],共6种不同施肥处理(F_(1)Y_(1)、F_(1)Y_(2)、F_(2)Y_(1)、F_(2)Y_(2)、Y_(1)、Y_(2)),以不施肥(CK_(1))和单施氮磷钾复合肥300 kg·hm^(−2)(CK_(2))为对照,探究复合肥与液体堆肥茶配施对林下菊苣草产量和营养品质及土壤特性的影响。结果表明:与CK_(1)、Y_(1)和Y_(2)处理相比,CK_(2)处理下菊苣全年鲜草产量分别显著提高66.00%、60.71%和68.90%(P<0.05),全年干草产量分别显著提高61.20%、49.36%和57.71%(P<0.05),而CK_(2)与F_(1)Y_(1)处理间各茬次和全年产量无显著差异(P>0.05)。不同配比组合施肥处理对林下第1茬和第2茬菊苣草的粗蛋白(CP)、粗脂肪(EE)、粗灰分(Ash)、酸性洗涤纤维(ADF)和中性洗涤纤维(NDF)含量影响趋势较为一致,CK_(2)处理下第1茬和第2茬菊苣草相对饲喂价值(RFV)分别较CK_(1)显著提高53.90%和52.68%(P<0.05),CK_(2)和F_(1)Y_(1)处理下第2茬草RFV值较CK_(1)显著提高57.93%和55.70%(P<0.05)。CK_(2)和F_(1)Y_(1)处理与其他施肥处理相比,均可有效提高0-10 cm和10-20 cm土层土壤有机质、碱解氮、全磷和全钾含量。CK_(2)与F_(1)Y_(1)处理较其他施肥处理可获得更高的菊苣草产量和RFV值,其中单施2种液体堆肥茶Y_(1)和Y_(2)处理间比较,香菇菌渣+鸡粪发酵的液体堆肥茶对菊苣草产量和营养品质及土壤营养成分的提升效果较好。 展开更多
关键词 林草复合 菊苣 施肥 草产量 品质
在线阅读 下载PDF
复合泵控液压系统模糊PID控制特性研究
19
作者 魏列江 万思毅 +1 位作者 路全锋 何小康 《机床与液压》 北大核心 2025年第20期64-70,共7页
为提高泵控液压缸系统的动态响应性能与控制精度,解决传统PID控制在多工况及能效优化方面的不足,提出一种基于模糊规则的PID参数实时整定复合控制策略。根据系统负载流量与压力需求,实时调节电机转速与液压泵排量,在保证动态性能的同时... 为提高泵控液压缸系统的动态响应性能与控制精度,解决传统PID控制在多工况及能效优化方面的不足,提出一种基于模糊规则的PID参数实时整定复合控制策略。根据系统负载流量与压力需求,实时调节电机转速与液压泵排量,在保证动态性能的同时实现运行能效优化。在AMESim中建立复合泵控液压缸系统模型,并在MATLAB/Simulink中构建模糊PID控制器,开展联合仿真分析。结果表明:与传统PID控制相比,所提模糊PID控制策略使系统阶跃响应时间缩短18%,超调量降低22%,有效提升了系统的响应速度与控制精度。该控制方法能够适应复合泵控液压系统的多工况需求,具有良好的参数协调能力与能效优化效果,为类似系统的控制策略设计提供了参考。 展开更多
关键词 复合泵控液压缸系统 联合仿真 模糊控制 响应时间
在线阅读 下载PDF
GCMS结合Compound Composer软件筛选PM2.5中有机污染物 被引量:3
20
作者 马英歌 戴海夏 +5 位作者 李莉 陈长虹 孙谦 范军 李月琪 黄涛宏 《环境化学》 CAS CSCD 北大核心 2018年第1期188-191,共4页
本文采用高压溶剂萃取(HPSE)方式萃取PM_2.5滤膜中的有机污染物,以气相色谱-质谱(GCMS)和Compound Composer软件进行筛查和半定量计算,同时以已知浓度的农药标样对Compound Composer软件的定性及半定量结果进行验证.结果表明,对1.0μg&#... 本文采用高压溶剂萃取(HPSE)方式萃取PM_2.5滤膜中的有机污染物,以气相色谱-质谱(GCMS)和Compound Composer软件进行筛查和半定量计算,同时以已知浓度的农药标样对Compound Composer软件的定性及半定量结果进行验证.结果表明,对1.0μg·L^(-1)的24种农药混标进行半定量分析,结果偏差在-0.707—0.643μg之间,相对误差在-70.74%—64.31%之间满足日常环境监测的要求.在无标样的情况下,对某地区不同时间的3个PM_2.5样品进行监测,筛查其中主要的有机污染物,并进行半定量计算,可及时掌握大气污染现状,为环境管理和来源解析提供有效数据. 展开更多
关键词 GCMS compound COMPOSER 高压溶剂萃取(HPSE) PM2.5 有机污染物.
在线阅读 下载PDF
上一页 1 2 51 下一页 到第
使用帮助 返回顶部