During the Twelfth Five-Year plan,large-scale construction of smart grid with safe and stable operation requires a timely and accurate short-term load forecasting method.Moreover,along with the full-scale smart grid c...During the Twelfth Five-Year plan,large-scale construction of smart grid with safe and stable operation requires a timely and accurate short-term load forecasting method.Moreover,along with the full-scale smart grid construction,the power supply mode and consumption mode of the whole system can be optimized through the accurate short-term load forecasting;and the security,stability and cleanness of the system can be guaranteed.展开更多
Different receptors have evolved in organisms to sense different stimuli in their surroundings.The interaction among the receptors can significantly increase sensory sensitivity and adaptation precision.To study the i...Different receptors have evolved in organisms to sense different stimuli in their surroundings.The interaction among the receptors can significantly increase sensory sensitivity and adaptation precision.To study the influence of interaction among different types of chemoreceptors on the adaptation rate in the bacterial chemotaxis signaling network,we systematically compared the adaptation time between the wild-type strain expressing mixed types of receptors and the mutant strain expressing only Tar receptors(namely,the Tar-only strain)under stepwise addition of different concentrations of L-aspartate using FRET(Förster resonance energy transfer)and bead assays.We find that the wild type exhibits faster adaptation than the mutant under the same concentration of saturated stimulus.In contrast,the wild type exhibits slower adaptation than the mutant under unsaturated stimuli that induce the same magnitude of response,and this is independent of the level of receptor expression.The same result is obtained for the network relaxation time by monitoring the steady-state rotational signal of the flagellar motors.By simulating bacterial chemotaxis with different adaptation rates in a stable gradient of chemoattractants,we confirm that the interaction of different types of receptors can effectively promote chemotaxis of Escherichia coli under a stable spatial gradient of attractants while ensuring minimum noise in the cell position distribution.展开更多
文摘During the Twelfth Five-Year plan,large-scale construction of smart grid with safe and stable operation requires a timely and accurate short-term load forecasting method.Moreover,along with the full-scale smart grid construction,the power supply mode and consumption mode of the whole system can be optimized through the accurate short-term load forecasting;and the security,stability and cleanness of the system can be guaranteed.
基金supported by the Natural Science Foundation of Anhui Province(2008085QA31).
文摘Different receptors have evolved in organisms to sense different stimuli in their surroundings.The interaction among the receptors can significantly increase sensory sensitivity and adaptation precision.To study the influence of interaction among different types of chemoreceptors on the adaptation rate in the bacterial chemotaxis signaling network,we systematically compared the adaptation time between the wild-type strain expressing mixed types of receptors and the mutant strain expressing only Tar receptors(namely,the Tar-only strain)under stepwise addition of different concentrations of L-aspartate using FRET(Förster resonance energy transfer)and bead assays.We find that the wild type exhibits faster adaptation than the mutant under the same concentration of saturated stimulus.In contrast,the wild type exhibits slower adaptation than the mutant under unsaturated stimuli that induce the same magnitude of response,and this is independent of the level of receptor expression.The same result is obtained for the network relaxation time by monitoring the steady-state rotational signal of the flagellar motors.By simulating bacterial chemotaxis with different adaptation rates in a stable gradient of chemoattractants,we confirm that the interaction of different types of receptors can effectively promote chemotaxis of Escherichia coli under a stable spatial gradient of attractants while ensuring minimum noise in the cell position distribution.
