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Optimization of Infrared-microwave Post-processing Process for 3D Printed Raspberry Preserves Based on AHP-CRITIC Hybrid Weighting Combined with Response Surface Method
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作者 Zheng Xianzhe Song Ruonan +2 位作者 Cong Hongyue Zhang Yuhan Xue Liangliang 《Journal of Northeast Agricultural University(English Edition)》 2025年第1期27-44,共18页
In order to improve the quality of 3D printed raspberry preserves after post-processing,microwave ovens combining infrared and microwave methods were utilized.The effects of infrared heating temperature,infrared heati... In order to improve the quality of 3D printed raspberry preserves after post-processing,microwave ovens combining infrared and microwave methods were utilized.The effects of infrared heating temperature,infrared heating time,microwave power,microwave heating time on the center temperature,moisture content,the chroma(C*),the total color difference(ΔE*),shape fidelity,hardness,and the total anthocyanin content of 3D printed raspberry preserves were analyzed by response surface method(RSM).The results showed that under combining with the two methods,infrared heating improved the fidelity and quality degradation of printed products,while microwave heating enhanced the efficiency of infrared heating.Infrared-microwave combination cooking could maintain relatively stable color appearance and shape of 3D printed raspberry preserves.The AHP–CRITIC hybrid weighting method combined with the response surface test to determine the comprehensive weights of the evaluation indicators optimized the process parameters,and the optimal process parameters were obtained:infrared heating temperature of 190℃,infrared heating time of 10 min and 30 s,microwave power of 300 W,and microwave heating time of 2 min and 6 s.The 3D printed raspberry cooking methods obtained under the optimal conditions seldom had color variation,porous structure,uniform texture,and high shape fidelity,which retained the characteristics of personalized manufacturing by 3D printing.This study could provide a reference for the postprocessing and quality control of 3D cooking methods. 展开更多
关键词 3D printing RASPBERRY MICROWAVE infrared heating hybrid weighting response surface method
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Extremum response surface method of reliability analysis on two-link flexible robot manipulator 被引量:19
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作者 ZHANG Chun-yi BAI Guang-chen 《Journal of Central South University》 SCIE EI CAS 2012年第1期101-107,共7页
In order to present a new method for analyzing the reliability of a two-link flexible robot manipulator,Lagrange dynamics differential equations of the two-link flexible robot manipulator were established by using the... In order to present a new method for analyzing the reliability of a two-link flexible robot manipulator,Lagrange dynamics differential equations of the two-link flexible robot manipulator were established by using the integrated modal method and the multi-body system dynamics method.By using the Monte Carlo method,the random sample values of the dynamic parameters were obtained and Lagrange dynamics differential equations were solved for each random sample value which revealed their displacement,speed and acceleration.On this basis,dynamic stresses and deformations were obtained.By taking the maximum values of the stresses and the deformations as output responses and the random sample values of dynamic parameters as input quantities,extremum response surface functions were established.A number of random samples were then obtained by using the Monte Carlo method and then the reliability was analyzed by using the extremum response surface method.The results show that the extremum response surface method is an efficient and fast reliability analysis method with high-accuracy for the two-link flexible robot manipulator. 展开更多
关键词 RELIABILITY Monte Carlo method extremum response surface function flexible manipulator dynamic strength dynamicstiffness
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Response surface method using grey relational analysis for decision making in weapon system selection 被引量:9
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作者 Peng Wang Peng Meng Baowei Song 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2014年第2期265-272,共8页
A proper weapon system is very important for a na- tional defense system. Generally, it means selecting the optimal weapon system among many alternatives, which is a multiple- attribute decision making (MADM) proble... A proper weapon system is very important for a na- tional defense system. Generally, it means selecting the optimal weapon system among many alternatives, which is a multiple- attribute decision making (MADM) problem. This paper proposes a new mathematical model based on the response surface method (RSM) and the grey relational analysis (GRA). RSM is used to obtain the experimental points and analyze the factors that have a significant impact on the selection results. GRA is used to an- alyze the trend relationship between alternatives and reference series. And then an RSM model is obtained, which can be used to calculate all alternatives and obtain ranking results. A real world application is introduced to illustrate the utilization of the model for the weapon selection problem. The results show that this model can be used to help decision-makers to make a quick comparison of alternatives and select a proper weapon system from multiple alternatives, which is an effective and adaptable method for solving the weapon system selection problem. 展开更多
关键词 weapon system multiple-attribute decision making(MADM) response surface method (RSM) grey relational analysis(GRA).
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Improved response surface method and its application in stability reliability degree analysis of tunnel surrounding rock 被引量:10
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作者 苏永华 张鹏 赵明华 《Journal of Central South University of Technology》 EI 2007年第6期870-876,共7页
An approach of limit state equation for surrounding rock was put forward based on deformation criterion. A method of symmetrical sampling of basic random variables adopted by classical response surface method was mend... An approach of limit state equation for surrounding rock was put forward based on deformation criterion. A method of symmetrical sampling of basic random variables adopted by classical response surface method was mended, and peak value and deflection degree of basic random variables distribution curve were took into account in the mended sampling method. A calculation way of probability moment, based on mended Rosenbluth method, suitable for non-explicit performance function was put forward. The first, second, third and fourth order moments of functional function value were calculated by mended Rosenbluth method through the first, second, third and fourth order moments of basic random variable. A probability density the function(PDF) of functional function was deduced through its first, second, third and fourth moments, the PDF in the new method took the place of the method of quadratic polynomial to approximate real functional function and reliability probability was calculated through integral by the PDF for random variable of functional function value in the new method. The result shows that the improved response surface method can adapt to various statistic distribution types of basic random variables, its calculation process is legible and need not itemtive circulation. In addition, a stability probability of surrounding rock for a tunnel was calculated by the improved method, whose workload is only 30% of classical method and its accuracy is comparative. 展开更多
关键词 response surface method Rosenbluth method statistic moment entropy density function quadratic polynomial
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Optimal design of butterfly-shaped linear ultrasonic motor using finite element method and response surface methodology 被引量:9
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作者 时运来 陈超 赵淳生 《Journal of Central South University》 SCIE EI CAS 2013年第2期393-404,共12页
A new method for optimizing a butterfly-shaped linear ultrasonic motor was proposed to maximize its mechanical output. The finite element analysis technology and response surface methodology were combined together to ... A new method for optimizing a butterfly-shaped linear ultrasonic motor was proposed to maximize its mechanical output. The finite element analysis technology and response surface methodology were combined together to realize the optimal design of the butterfly-shaped linear ultrasonic motor. First, the operation principle of the motor was introduced. Second, the finite element parameterized model of the stator of the motor was built using ANSYS parametric design language and some structure parameters of the stator were selected as design variables. Third, the sample points were selected in design variable space using latin hypercube Design. Through modal analysis and harmonic response analysis of the stator based on these sample points, the target responses were obtained. These sample points and response values were combined together to build a response surface model. Finally, the simplex method was used to find the optimal solution. The experimental results showed that many aspects of the design requirements of the butterfly-shaped linear ultrasonic motor have been fulfilled. The prototype motor fabricated based on the optimal design result exhibited considerably high dynamic performance, such as no-load speed of 873 ram/s, maximal thrust of 27.5 N, maximal efficiency of 43%, and thrust-weight ratio of 45.8. 展开更多
关键词 linear ultrasonic motor PIEZOELECTRIC optimal design response surface methodology finite element method
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A Stochastic Response Surface Method for Probabilistic Evaluation of the Voltage Stability Considering Wind Power 被引量:6
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作者 BAO Haibo WEI Hua 《中国电机工程学报》 EI CSCD 北大核心 2012年第13期I0011-I0011,共1页
The traditional voltage stability analysis method is mostly based on the deterministic mode1.and ignores the uncertainties of bus loads,power supplies,changes in network configuration and so on.However,the great expan... The traditional voltage stability analysis method is mostly based on the deterministic mode1.and ignores the uncertainties of bus loads,power supplies,changes in network configuration and so on.However,the great expansion of renewable power generations such as wind and solar energy in a power system has increased their uncertainty,and仃aditional techniques are limited in capturing their variable behavior.This leads to greater needs of new techniques and methodologies to properly quan tify the voltage stability of power systems. 展开更多
关键词 power systems stochastic response surface voltage stability probabilistic evaluation wind power generation imerior point methods
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Reliability analysis for aeroengine turbine disc fatigue life with multiple random variables based on distributed collaborative response surface method 被引量:2
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作者 高海峰 白广忱 +1 位作者 高阳 鲍天未 《Journal of Central South University》 SCIE EI CAS CSCD 2015年第12期4693-4701,共9页
The fatigue life of aeroengine turbine disc presents great dispersion due to the randomness of the basic variables,such as applied load,working temperature,geometrical dimensions and material properties.In order to am... The fatigue life of aeroengine turbine disc presents great dispersion due to the randomness of the basic variables,such as applied load,working temperature,geometrical dimensions and material properties.In order to ameliorate reliability analysis efficiency without loss of reliability,the distributed collaborative response surface method(DCRSM) was proposed,and its basic theories were established in this work.Considering the failure dependency among the failure modes,the distributed response surface was constructed to establish the relationship between the failure mode and the relevant random variables.Then,the failure modes were considered as the random variables of system response to obtain the distributed collaborative response surface model based on structure failure criterion.Finally,the given turbine disc structure was employed to illustrate the feasibility and validity of the presented method.Through the comparison of DCRSM,Monte Carlo method(MCM) and the traditional response surface method(RSM),the results show that the computational precision for DCRSM is more consistent with MCM than RSM,while DCRSM needs far less computing time than MCM and RSM under the same simulation conditions.Thus,DCRSM is demonstrated to be a feasible and valid approach for improving the computational efficiency of reliability analysis for aeroengine turbine disc fatigue life with multiple random variables,and has great potential value for the complicated mechanical structure with multi-component and multi-failure mode. 展开更多
关键词 complicated mechanical structure reliability analysis multiple random variables multi-component and multi-failure mode distributed collaborative response surface method
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Distributed collaborative extremum response surface method for mechanical dynamic assembly reliability analysis 被引量:7
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作者 费成巍 白广忱 《Journal of Central South University》 SCIE EI CAS 2013年第9期2414-2422,共9页
To make the dynamic assembly reliability analysis more effective for complex machinery of multi-object multi-discipline(MOMD),distributed collaborative extremum response surface method(DCERSM)was proposed based on ext... To make the dynamic assembly reliability analysis more effective for complex machinery of multi-object multi-discipline(MOMD),distributed collaborative extremum response surface method(DCERSM)was proposed based on extremum response surface method(ERSM).Firstly,the basic theories of the ERSM and DCERSM were investigated,and the strengths of DCERSM were proved theoretically.Secondly,the mathematical model of the DCERSM was established based upon extremum response surface function(ERSF).Finally,this model was applied to the reliability analysis of blade-tip radial running clearance(BTRRC)of an aeroengine high pressure turbine(HPT)to verify its advantages.The results show that the DCERSM can not only reshape the possibility of the reliability analysis for the complex turbo machinery,but also greatly improve the computational speed,save the computational time and improve the computational efficiency while keeping the accuracy.Thus,the DCERSM is verified to be feasible and effective in the dynamic assembly reliability(DAR)analysis of complex machinery.Moreover,this method offers an useful insight for designing and optimizing the dynamic reliability of complex machinery. 展开更多
关键词 complex machinery dynamic assembly reliability (DAR) blade-tip radial running clearance (BTRRC) radial deformation reliability analysis distributed collaborative extremum response surface method (DCERSM) multi-object multidiscipline (MOMD)
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Optimizing rhamnolipid production by Pseudomonas aeruginosa ATCC 9027 grown on waste frying oil using response surface method and batch-fed fermentation 被引量:1
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作者 罗致 袁兴中 +4 位作者 钟华 曾光明 刘智峰 马小玲 朱雅婷 《Journal of Central South University》 SCIE EI CAS 2013年第4期1015-1021,共7页
Rhamnolipid production by Pseudomonas aeruginosa ATCC 9027 with waste frying oil as sole carbon source was studied using response surface method. Cultures were incubated in shaking flask with temperature, NO3- and Mg2... Rhamnolipid production by Pseudomonas aeruginosa ATCC 9027 with waste frying oil as sole carbon source was studied using response surface method. Cultures were incubated in shaking flask with temperature, NO3- and Mg2+ concentrations as the variables. Meanwhile, fed-batch fermentation experiments were conducted. The results show that the three variables are closely related to rhamnolipid production. The optimal cultivation conditions are of 6.4 g/L NaNO3 , 3.1 g/L MgSO4 at 32 ℃, with the maximum rhamnolipid production of 6.6 g/L. The results of fed-batch fermentation experiments show that feeding the oil in two batches can enhance rhamnolipid production. The best time interval is 72 h with the maximum rhamnolipid production of 8.5 g/L. The data are potentially useful for mass production of rhamnolipid on oil waste with this bacterium. 展开更多
关键词 Pseudomonas aeruginosa RHAMNOLIPID waste frying oil response surface method FED-BATCH
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Reliability-based design optimization for flexible mechanism with particle swarm optimization and advanced extremum response surface method 被引量:1
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作者 张春宜 宋鲁凯 +2 位作者 费成巍 郝广平 刘令君 《Journal of Central South University》 SCIE EI CAS CSCD 2016年第8期2001-2007,共7页
To improve the computational efficiency of the reliability-based design optimization(RBDO) of flexible mechanism, particle swarm optimization-advanced extremum response surface method(PSO-AERSM) was proposed by integr... To improve the computational efficiency of the reliability-based design optimization(RBDO) of flexible mechanism, particle swarm optimization-advanced extremum response surface method(PSO-AERSM) was proposed by integrating particle swarm optimization(PSO) algorithm and advanced extremum response surface method(AERSM). Firstly, the AERSM was developed and its mathematical model was established based on artificial neural network, and the PSO algorithm was investigated. And then the RBDO model of flexible mechanism was presented based on AERSM and PSO. Finally, regarding cross-sectional area as design variable, the reliability optimization of flexible mechanism was implemented subject to reliability degree and uncertainties based on the proposed approach. The optimization results show that the cross-section sizes obviously reduce by 22.96 mm^2 while keeping reliability degree. Through the comparison of methods, it is demonstrated that the AERSM holds high computational efficiency while keeping computational precision for the RBDO of flexible mechanism, and PSO algorithm minimizes the response of the objective function. The efforts of this work provide a useful sight for the reliability optimization of flexible mechanism, and enrich and develop the reliability theory as well. 展开更多
关键词 reliability-based design optimization flexible robot manipulator artificial neural network particle swarm optimization advanced extremum response surface method
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Vibration reliability analysis for aeroengine compressor blade based on support vector machine response surface method
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作者 高海峰 白广忱 《Journal of Central South University》 SCIE EI CAS CSCD 2015年第5期1685-1694,共10页
To ameliorate reliability analysis efficiency for aeroengine components, such as compressor blade, support vector machine response surface method(SRSM) is proposed. SRSM integrates the advantages of support vector mac... To ameliorate reliability analysis efficiency for aeroengine components, such as compressor blade, support vector machine response surface method(SRSM) is proposed. SRSM integrates the advantages of support vector machine(SVM) and traditional response surface method(RSM), and utilizes experimental samples to construct a suitable response surface function(RSF) to replace the complicated and abstract finite element model. Moreover, the randomness of material parameters, structural dimension and operating condition are considered during extracting data so that the response surface function is more agreeable to the practical model. The results indicate that based on the same experimental data, SRSM has come closer than RSM reliability to approximating Monte Carlo method(MCM); while SRSM(17.296 s) needs far less running time than MCM(10958 s) and RSM(9840 s). Therefore,under the same simulation conditions, SRSM has the largest analysis efficiency, and can be considered a feasible and valid method to analyze structural reliability. 展开更多
关键词 VIBRATION reliability analysis compressor blade support vector machine response surface method natural frequency
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Optimization of Freeze-drying Protective Agents for Lactobacillus plantarum KLDS1.0391 by Response Surface Methodology
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作者 Jia Fang-fang Han Bing +2 位作者 Meng Xiang-chen Zhang Lu-ji Zhou Jin-yu 《Journal of Northeast Agricultural University(English Edition)》 CAS 2017年第2期74-80,共7页
In this study, the Single Factor Test(SFT) was used to optimize the pre-freezing conditions of L. plantarum KLDS1.0391(KLDS1.0391). Further, the Freeze-Drying Protective Agents(FDPA) of KLDS1.0391 was optimized ... In this study, the Single Factor Test(SFT) was used to optimize the pre-freezing conditions of L. plantarum KLDS1.0391(KLDS1.0391). Further, the Freeze-Drying Protective Agents(FDPA) of KLDS1.0391 was optimized by Response Surface Methodology(RSM). The optimum pretreatment conditions were as the follows: initial concentration of KLDS1.0391 was 1011 CFU · m L-1 and KLDS1.0391 was pre-freezed at –80℃ for 8 h to achieve the survival rate of 46.21%. The main components of FDPA were skim milk, sucrose, sodium glutamate and Tween-80. And the influence of four factors on the survival rate of KLDS1.0391 in freeze-drying was in order as the follows: skim milk〉sucrose〉Tween-80〉sodium glutamate. The optimal FDPA composition was skim milk 11.3%, sucrose 9.8%, sodium glutamate 5.1% and Tween-80 0.2%. Under the above conditions, the survival rate of the cells was 82.98%. Comparing the predicted values, the relative error was 0.37% and the difference was not significant, which indicated that the established model could effectively reflect the actual protection of FDPA to KLDS1.0391. 展开更多
关键词 Lactobacillus plantarum response surface method freeze drying protective agent
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Application of response surface method for optimal transfer conditions of multi-layer ceramic capacitor alignment system
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作者 PARK Su-seong KIM Jae-min +1 位作者 CHUNG Won-jee SHIN O-chul 《Journal of Central South University》 SCIE EI CAS 2011年第3期726-730,共5页
The multi-layer ceramic capacitor (MLCC) alignment system aims at the inter-process automation between the first and the second plastic processes.As a result of testing performance verification of MLCC alignment syste... The multi-layer ceramic capacitor (MLCC) alignment system aims at the inter-process automation between the first and the second plastic processes.As a result of testing performance verification of MLCC alignment system,the average alignment rates are 95% for 3216 chip,88.5% for 2012 chip and 90.8% for 3818 chip.The MLCC alignment system can be accepted for practical use because the average manual alignment is just 80%.In other words,the developed MLCC alignment system has been upgraded to a great extent,compared with manual alignment.Based on the successfully developed MLCC alignment system,the optimal transfer conditions have been explored by using RSM.The simulations using ADAMS has been performed according to the cube model of CCD.By using MiniTAB,the model of response surface has been established based on the simulation results.The optimal conditions resulted from the response optimization tool of MiniTAB has been verified by being assigned to the prototype of MLCC alignment system. 展开更多
关键词 multi-layer ceramic capacitor (MLCC) alignment system response surface method (RSM) MiniTAB ADAMS
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Reliability and sensitivity analyses of HPT blade-tip radial running clearance using multiply response surface model 被引量:5
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作者 翟学 费成巍 +1 位作者 翟庆刚 王建军 《Journal of Central South University》 SCIE EI CAS 2014年第11期4368-4377,共10页
To reasonably design the blade-tip radial running clearance(BTRRC) of high pressure turbine and improve the performance and reliability of gas turbine, the multi-object multi-discipline reliability sensitivity analysi... To reasonably design the blade-tip radial running clearance(BTRRC) of high pressure turbine and improve the performance and reliability of gas turbine, the multi-object multi-discipline reliability sensitivity analysis of BTRRC was accomplished from a probabilistic prospective by considering nonlinear material attributes and dynamic loads. Firstly, multiply response surface model(MRSM) was proposed and the mathematical model of this method was established based on quadratic function. Secondly, the BTRRC was decomposed into three sub-components(turbine disk, blade and casing), and then the single response surface functions(SRSFs) of three structures were built in line with the basic idea of MRSM. Thirdly, the response surface function(MRSM) of BTRRC was reshaped by coordinating SRSFs. From the analysis, it is acquired to probabilistic distribution characteristics of input-output variables, failure probabilities of blade-tip clearance under different static blade-tip clearances δ and major factors impacting BTRRC. Considering the reliability and efficiency of gas turbine, δ=1.87 mm is an optimally acceptable option for rational BTRRC. Through the comparison of three analysis methods(Monte Carlo method, traditional response surface method and MRSM), the results show that MRSM has higher accuracy and higher efficiency in reliability sensitivity analysis of BTRRC. These strengths are likely to become more prominent with the increasing times of simulations. The present study offers an effective and promising approach for reliability sensitivity analysis and optimal design of complex dynamic assembly relationship. 展开更多
关键词 high pressure turbine blade-tip radial running clearance reliability sensitivity analysis multiply response surface method
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Evaluation of surface roughness and optimization of cutting parameters in turning of AA2024 alloy under different cooling-lubrication conditions using RSM method 被引量:3
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作者 Seyed Hasan MUSAVI Behnam DAVOODI Behzad ESKANDARI 《Journal of Central South University》 SCIE EI CAS CSCD 2020年第6期1714-1728,共15页
In the present study,the effect of reduction of cutting fluid consumption on the surface quality and tool wear was studied.Mathematical models were developed to predict the surface roughness using response surface met... In the present study,the effect of reduction of cutting fluid consumption on the surface quality and tool wear was studied.Mathematical models were developed to predict the surface roughness using response surface methodology(RSM).Analysis of variance(ANOVA)was used to investigate the significance of the developed regression models.The results showed that the coefficient of determination values(R^2)for the developed models was 97.46%for dry,89.32%for flood mode(FM),and 99.44%for MQL,showing the high accuracy of fitted models.Also,under the minimum quantity lubrication(MQL)condition,the surface roughness improved by 23%−44%and 19%−41%compared with dry and FM,respectively,and the SEM images of machined surface proved the statement.The prepared SEM images of tool rake face also showed a considerable decrease in adhesion wear.Built-up edge and built-up layer were the two main products of the adhesion wear,and energy-dispersive X-ray spectroscopy(EDX)analysis of specific points on the tool faces helped to discover the chemical compositions of adhered materials.By changing dry and FM to MQL mode,dominant mechanism of tool wear in machining aluminum alloy was significantly decreased.Breakage wear that led to early failure of cutting edge was also controlled by MQL technique. 展开更多
关键词 cooling-lubrication methods surface roughness minimum quantity lubrication response surface methodology AA2024 aluminum alloy
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Nonlinear finite-element-based structural system failure probability analysis methodology for gravity dams considering correlated failure modes 被引量:5
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作者 胡江 马福恒 吴素华 《Journal of Central South University》 SCIE EI CAS CSCD 2017年第1期178-189,共12页
The structural system failure probability(SFP) is a valuable tool for evaluating the global safety level of concrete gravity dams.Traditional methods for estimating the failure probabilities are based on defined mathe... The structural system failure probability(SFP) is a valuable tool for evaluating the global safety level of concrete gravity dams.Traditional methods for estimating the failure probabilities are based on defined mathematical descriptions,namely,limit state functions of failure modes.Several problems are to be solved in the use of traditional methods for gravity dams.One is how to define the limit state function really reflecting the mechanical mechanism of the failure mode;another is how to understand the relationship among failure modes and enable the probability of the whole structure to be determined.Performing SFP analysis for a gravity dam system is a challenging task.This work proposes a novel nonlinear finite-element-based SFP analysis method for gravity dams.Firstly,reasonable nonlinear constitutive modes for dam concrete,concrete/rock interface and rock foundation are respectively introduced according to corresponding mechanical mechanisms.Meanwhile the response surface(RS) method is used to model limit state functions of main failure modes through the Monte Carlo(MC) simulation results of the dam-interface-foundation interaction finite element(FE) analysis.Secondly,a numerical SFP method is studied to compute the probabilities of several failure modes efficiently by simple matrix integration operations.Then,the nonlinear FE-based SFP analysis methodology for gravity dams considering correlated failure modes with the additional sensitivity analysis is proposed.Finally,a comprehensive computational platform for interfacing the proposed method with the open source FE code Code Aster is developed via a freely available MATLAB software tool(FERUM).This methodology is demonstrated by a case study of an existing gravity dam analysis,in which the dominant failure modes are identified,and the corresponding performance functions are established.Then,the dam failure probability of the structural system is obtained by the proposed method considering the correlation relationship of main failure modes on the basis of the mechanical mechanism analysis with the MC-FE simulations. 展开更多
关键词 gravity dam structural system failure probability nonlinear finite element response surface method computational platform
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响应面法优化非达霉素发酵培养基及中试应用 被引量:1
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作者 张莉 米贯东 +3 位作者 王昂 任风芝 林旸 李晓露 《中国抗生素杂志》 北大核心 2025年第1期41-49,共9页
目的筛选非达霉素游动放线菌FD-13-194,优化发酵培养基组分,提高非达霉素发酵产量,为其工业化生产奠定基础。方法基于单因素实验结果,通过Plackett-Burman实验、最陡爬坡实验和响应面法,进行产非达霉素发酵培养基配方的优选。结果产非... 目的筛选非达霉素游动放线菌FD-13-194,优化发酵培养基组分,提高非达霉素发酵产量,为其工业化生产奠定基础。方法基于单因素实验结果,通过Plackett-Burman实验、最陡爬坡实验和响应面法,进行产非达霉素发酵培养基配方的优选。结果产非达霉素的最优发酵培养基配方为:葡萄糖30 g/L、糊精60.4 g/L、玉米蛋白粉10 g/L、黄豆饼粉10 g/L、蛋白胨20 g/L、NaCl 2.3 g/L、Tween-802 g/L和CaCO_(3)4 g/L。使用该配方,在2 T罐中非达霉素的平均发酵产量达到3501 mg/L,比原配方提高了36.1%,同时有效去除了副产物杂质1和2,杂质3的比例降低10%以上,中试放大效果良好。结论采用响应面法优化菌株FD-13-194的发酵培养基,在实验室和中试生产中显著提高了非达霉素的发酵产量,展现出极大的工业应用潜力。 展开更多
关键词 非达霉素 游动放线菌 响应面法 中试发酵
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水蒸气蒸馏提取肉桂精油工艺及成分的分析 被引量:3
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作者 刘婷 朱慧 +5 位作者 才让东珠 成述儒 罗志皓 易雪娇 张涛 陈欢 《中国粮油学报》 北大核心 2025年第1期149-155,共7页
为提高肉桂精油提取率,本实验选用水蒸气蒸馏法,首先通过单因素实验,研究分析4个因素(蒸馏时间、料液比、浸泡时间、料液中氯化钠的体积分数)对肉桂精油提取率的影响;然后利用响应面设计对肉桂精油提取工艺进行优化;最后借助气相色谱-... 为提高肉桂精油提取率,本实验选用水蒸气蒸馏法,首先通过单因素实验,研究分析4个因素(蒸馏时间、料液比、浸泡时间、料液中氯化钠的体积分数)对肉桂精油提取率的影响;然后利用响应面设计对肉桂精油提取工艺进行优化;最后借助气相色谱-质谱联用技术(GC-MS)对其成分、含量进行测定分析。结果表明:提取率的回归方程相关系数R 2=0.98,方程回归模型极显著(P<0.01),回归模型拟合性较好,肉桂精油最佳提取条件为:蒸馏时间3 h,料液比1∶13,浸泡时间40 min,氯化钠的体积分数3.6%,且在该条件下提取率约为3.30%;最佳工艺提取的肉桂精油共检测出75种成分,占总精油的87.32%,其主要成分为反式肉桂醛。 展开更多
关键词 肉桂精油 水蒸气蒸馏 提取率 响应面设计 成分分析
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基于响应面法的天然气压差发电参数优化 被引量:1
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作者 张朋岗 杨冬磊 +3 位作者 程曦 骆兴龙 李玮 李有江 《石油与天然气化工》 北大核心 2025年第2期62-70,共9页
目的解决压差发电装置发电功率低的问题,优化工艺参数。方法①通过常规㶲及高级㶲分析法发现透平膨胀机可避免外源㶲损占比达42%,表明装置自身的运行参数设置不合理,导致了高㶲损。②采用响应面法分析和优化运行参数,以进出口压力比、进口... 目的解决压差发电装置发电功率低的问题,优化工艺参数。方法①通过常规㶲及高级㶲分析法发现透平膨胀机可避免外源㶲损占比达42%,表明装置自身的运行参数设置不合理,导致了高㶲损。②采用响应面法分析和优化运行参数,以进出口压力比、进口温度、天然气体积流量作为因素变量,以发电功率、总㶲损作为响应值,设计13组试验。结果进出口压力比和天然气体积流量间的交互作用对发电功率的影响最显著,进出口压力比和天然气体积流量的交互作用、进口温度和天然气体积流量的交互作用对总㶲损的影响显著。据此,提出通过提高进出口压力比、天然气体积流量和降低进口温度的方式来进行参数优化的策略。根据优化后的工艺参数调整现场参数:进出口压力比为1.38、进口温度为30.7℃、天然气体积流量为11×10^(4)m^(3)/h,此时,发电功率达到625.3 kW,总㶲损降低了180.9 kW,其中,透平膨胀机㶲效率增至72.3%,可避免的外源㶲损减少了104.4 kW。此外,装置的年经济效益增加了114.5万元,CO_(2)的年排放量减少了1109.5 t。结论针对各类复杂的天然气处理工艺,可使用高级㶲分析与响应面分析的组合优化法。首先,利用高级㶲分析量化工艺改进的潜力;若可避免外源㶲损占比较大,则再采用响应面法进一步进行参数优化。 展开更多
关键词 天然气 压差发电 高级㶲分析 交互作用 响应面法
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芪葛颗粒干法制粒工艺优化及其物理指纹图谱建立 被引量:1
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作者 李航 周恩丽 +3 位作者 汪盛华 张欣 肖伟 王振中 《中成药》 北大核心 2025年第2期401-407,共7页
目的优化芪葛颗粒干法制粒工艺,并建立其物理指纹图谱。方法正交试验优化干燥工艺,单因素试验优化填充剂、矫味剂。以送料速度、轧轮转速、轧轮压力为影响因素,一次成型率、吸湿率、溶化率、休止角的综合评分为评价指标,Box-Behnken响... 目的优化芪葛颗粒干法制粒工艺,并建立其物理指纹图谱。方法正交试验优化干燥工艺,单因素试验优化填充剂、矫味剂。以送料速度、轧轮转速、轧轮压力为影响因素,一次成型率、吸湿率、溶化率、休止角的综合评分为评价指标,Box-Behnken响应面法优化干法制粒工艺。结果最佳干燥工艺为一区、二区、三区加热温度130、125、120℃,履带传送频率10 Hz,浸膏相对密度1.2;最佳填充剂为糊精;最佳矫味剂为0.5%甜菊糖苷和0.5%甜橙香精;最佳干法制粒工艺为送料速度28 Hz,轧轮速度17 Hz,轧轮压力7 MPa,综合评分为0.7465。15批样品物理指纹图谱相似度均大于0.98。结论该工艺稳定可行,可为芪葛颗粒的工业化生产提供参考。 展开更多
关键词 芪葛颗粒 干法制粒工艺 物理指纹图谱 Box-Behnken响应面法
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