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Trigger转座子衍生蛋白1对肝癌细胞生长的影响
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作者 高平 叶子坚 +1 位作者 钱晓宇 钟秀颖 《华南理工大学学报(自然科学版)》 EI CAS CSCD 北大核心 2024年第4期1-7,共7页
细胞周期失调是肿瘤重要的标志之一,生物信息学分析结果表明,Trigger转座子衍生蛋白1(TIGD1)在临床肝癌组织中高表达且与细胞周期相关,但相关机制未知。为了探究TIGD1调控肝癌细胞生长的具体机制,首先,利用shRNA质粒构建靶向敲低TIGD1... 细胞周期失调是肿瘤重要的标志之一,生物信息学分析结果表明,Trigger转座子衍生蛋白1(TIGD1)在临床肝癌组织中高表达且与细胞周期相关,但相关机制未知。为了探究TIGD1调控肝癌细胞生长的具体机制,首先,利用shRNA质粒构建靶向敲低TIGD1的肝癌细胞系Hep3B,并分析TIGD1敲低对肝癌细胞生长的影响,结果表明细胞生长受阻;接着,通过细胞流式技术分析TIGD1敲低对肝癌细胞周期进程的影响,结果显示,TIGD1敲低的Hep3B细胞系的细胞周期进程主要阻滞于G2/M期;然后,通过免疫沉淀(IP)实验验证TIGD1可能发生相互结合的蛋白分子,结果表明,TIGD1可能与Aurora激酶相互作用蛋白1(AURKAIP1)存在相互结合,进一步的Co-IP实验证实了TIGD1和AURKAIP1之间的相互作用。已知AURKAIP1可调控Aurora激酶A(AURKA)的蛋白酶体降解途径,AURKA是一种有丝分裂调控蛋白,与细胞周期进程密切相关。文中进一步探究TIGD1对AURKA蛋白水平的影响,实验结果表明,在TIGD1敲低的情况下,AURKA在Hep3B细胞系中的蛋白水平明显下调,mRNA水平没有明显变化。综上所述,TIGD1可能通过调控AURKA在肝癌细胞中的转录后水平来影响细胞周期进程,从而影响肝癌的发生发展。 展开更多
关键词 trigger转座子衍生蛋白1 肝癌 细胞生长 细胞周期
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基于trigger对的蒙古语语言模型的三种实现方法比较 被引量:1
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作者 刘志文 侯宏旭 +1 位作者 李沙茹拉 柳林 《中文信息学报》 CSCD 北大核心 2009年第6期105-109,共5页
基于trigger对的长距离蒙古语语言模型采用统计方法进行自然语言建模。该文简要介绍了基于trigger对的长距离蒙古语语言模型的三种实现方法,并在汉语-蒙古语机器翻译系统测试了这三种方法的性能。该文旨在通过对三种模型的比较研究,为基... 基于trigger对的长距离蒙古语语言模型采用统计方法进行自然语言建模。该文简要介绍了基于trigger对的长距离蒙古语语言模型的三种实现方法,并在汉语-蒙古语机器翻译系统测试了这三种方法的性能。该文旨在通过对三种模型的比较研究,为基于trigger对的长距离蒙古语语言模型的具体应用提供参考和依据。 展开更多
关键词 人工智能 自然语言处理 trigger 蒙古语 语言模型
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Trigger在工作流设计中的应用
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作者 马捷 唐胜群 +1 位作者 刘伟 夏伦先 《计算机工程与科学》 CSCD 2002年第6期5-7,37,共4页
在动态环境中设计工作流 ,需要一个具有高灵活性和易于使用的工作流模型。在工作流设计中建立独立于主工作流之外的异常情况模型 ,可以扩展工作流设计所应用的范围。本文以河南省电力公司管理系统中的具体实践为例 。
关键词 trigger 工作流 设计 异常处理 软件系统 事务处理
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Scott Triggers评分表与Munro量表评估手术患者压力性损伤的效果比较 被引量:29
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作者 史桂蓉 王晓慧 +4 位作者 刘萍 冯晓岚 黄萍 张培培 姜丽萍 《护理学杂志》 CSCD 北大核心 2020年第7期43-46,共4页
目的比较Scott Triggers(ST)评分表与Munro量表对手术患者压力性损伤发生的评估效果,为临床选择合适的评估工具提供参考.方法使用ST评分表和Munro量表对413例手术患者进行压力性损伤风险评估,以术后压疮实际发生数为金标准,采用ROC曲线... 目的比较Scott Triggers(ST)评分表与Munro量表对手术患者压力性损伤发生的评估效果,为临床选择合适的评估工具提供参考.方法使用ST评分表和Munro量表对413例手术患者进行压力性损伤风险评估,以术后压疮实际发生数为金标准,采用ROC曲线和Bayes判别分析ST评分表与Munro量表的评估能力.结果共有43例(10.41%)手术患者发生压力性损伤;ST评分表与Munro量表曲线下面积分别是0.626(95%CI:0.578~0.673)、0.670(95%CI:0.622~0.715),两者差异无统计学意义(P>0.05);交叉验证法对函数进行验证,Munro量表与ST评分表的正判率,分别为89.60%、89.80%.结论ST评分表和Mun-ro量表评估效果相近均可用于手术患者压力性损伤的评估,ST评分表条目少而简洁,应用更便捷. 展开更多
关键词 手术患者 压力性损伤 Munro量表 SCOTT triggers评分表 风险评估 评估工具 评估能力
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基于Trigger的长距离语言模型 被引量:4
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作者 苏韬 孙甲松 王作英 《计算机工程与应用》 CSCD 北大核心 2002年第18期59-61,共3页
文章利用Trigger模型描述长距离的词与词之间的关系,并将其与目前通用的N元文法语言模型相结合,同时通过引入参数———置信度来提高Trigger模型得分的可靠性,在汉语自动语音识别系统中实现了一个可实用化的长距离语言模型。实验表明,... 文章利用Trigger模型描述长距离的词与词之间的关系,并将其与目前通用的N元文法语言模型相结合,同时通过引入参数———置信度来提高Trigger模型得分的可靠性,在汉语自动语音识别系统中实现了一个可实用化的长距离语言模型。实验表明,二者的结合在一定程度上克服了N元文法语言模型描述距离小于N的缺点,提高了系统的识别率。 展开更多
关键词 trigger模型 长距离语言模型 置信度 语音识别
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利用FP-树构造多词Trigger对语言模型 被引量:2
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作者 许永林 史晓东 蔡骏 《厦门大学学报(自然科学版)》 CAS CSCD 北大核心 2005年第B06期243-246,共4页
在语音识别系统中,Trigger模型作为语言模型的一种,用于描述长距离词与词之间的关系,然而以往的Trigger语言模型多是针对单个词的模型,本文借鉴数据挖掘中关联规则发现的Apriori算法,利用效率比较高的FP树算法产生多词Trigger对,由此构... 在语音识别系统中,Trigger模型作为语言模型的一种,用于描述长距离词与词之间的关系,然而以往的Trigger语言模型多是针对单个词的模型,本文借鉴数据挖掘中关联规则发现的Apriori算法,利用效率比较高的FP树算法产生多词Trigger对,由此构造多词Trigger对语言模型,这种模型能够更多地利用历史数据,弥补了传统N元文法语言模型描述距离小于N的缺点. 展开更多
关键词 trigger 语言模型 FP-树 构造 Apriori算法 语音识别系统 关联规则发现 er模型 数据挖掘 效率比较 模型描述 N元文法 历史数据 长距离 树算法
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基于移动通信切换特性的L2-Trigger方法 被引量:3
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作者 唐宏 陶京涛 +2 位作者 王柏丁 韦泉 吴中福 《计算机应用》 CSCD 北大核心 2006年第12期2796-2799,共4页
有文献提出采用二层触发器提前触发三层切换的方法以适应移动IP中的实时应用,但是现有的方法存在指示不准确、触发方法不明确等问题。为此,给出了新的二层触发器方法,并给出具体的路由更新协议DRPR,从而消除了移动节点(MN)切换时的注册... 有文献提出采用二层触发器提前触发三层切换的方法以适应移动IP中的实时应用,但是现有的方法存在指示不准确、触发方法不明确等问题。为此,给出了新的二层触发器方法,并给出具体的路由更新协议DRPR,从而消除了移动节点(MN)切换时的注册时延。 展开更多
关键词 移动IP 二层触发器 双路由提前注册
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A reusable planar triggered spark-gap switch batched-fabricated with PCB technology for medium- and low-voltage pulse power systems 被引量:3
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作者 Zhi Yang Ke Wang +5 位作者 Peng Zhu Peng Liu Qiu Zhang Cong Xu Hao-tian Jian Rui-qi Shen 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2021年第4期1572-1578,共7页
Triggered spark-gap switch is a popular discharge switch for pulse power systems.Previous studies have focused on planarizing this switch using thin film techniques in order to meet the requirements of compact size in... Triggered spark-gap switch is a popular discharge switch for pulse power systems.Previous studies have focused on planarizing this switch using thin film techniques in order to meet the requirements of compact size in the systems.Such switches are one-shot due to electrodes being too thin to sufficiently resist spark-erosion.Additionally,these switches did not employ any structures in securing internal gas composition,resulting in inconsistent performance under harsh atmospheres.In this work,a novel planar triggered spark-gap switch(PTS)with a hermetically sealed cavity was batched-prepared with printed circuit board(PCB)technology,to achieve reusability with low cost.The proposed PTS was inspected by micro-computed tomography to ensure PCB techniques meet the requirements of machining precision.The results from electrical experiments demonstrated that PCB PTS were consistent and reusable with lifespan over 20 times.The calculated switch voltage and circuit current were consistent with those derived from real-world measurements.Finally,PCB PTS was used to introduce hexanitrostilbene(HNS)pellets in a pulse power system to verify its performance. 展开更多
关键词 Pulse power systems Printed circuit board technology triggered spark-gap switch Planar discharge switch Electrical performance
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Trigger control characteristics of fuze-recoil simulation system based on electromagnetic launcher 被引量:1
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作者 Wenhao Wang Shihua Bi +2 位作者 Hongjun Xiang Chao Zhan Xichao Yuan 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2017年第3期563-571,共9页
Fuze is the information processing and control unit of the ammunition, so the quality of the fuze becomes one of the most important aspects of ammunition detection. Since using recoil force is a common method to the a... Fuze is the information processing and control unit of the ammunition, so the quality of the fuze becomes one of the most important aspects of ammunition detection. Since using recoil force is a common method to the arm fuze, its dynamic simulation test has always been the focus of the fuze test research. A new fuze recoil environmental simulation method is proposed based on the electromagnetic launcher. Then the trigger control characteristics of the fuze recoil simulation system and the influence of the trigger position on the recoil force are studied. The results of the study show that although the pulse width of the armature force curve can be changed by adjusting the trigger position, due to the limit of the range, there also exists the contradiction that the electromagnetic pulse width gets narrow with the increase of electromagnetic force peak. Thus, it cannot meet the requirements of the fuze launch recoil simulation. In order to make the recoil force close to the actual environment, the multi-stage trigger control characteristics are analyzed, and the influence of trigger position on recoil environmental force characteristics is studied. Then a fuze launch recoil environmental simulation platform is established and continuous electromagnetic force is achieved by using the trigger strategy. Finally, the experiment is performed to simulate the fuze launch recoil environment and show the feasibility and effectiveness of the proposed theoretical analysis. The major research work of this paper includes studying the composition and basic principle of the simulation system, establishing a launch model to analyze the single-stage and multi-stage coil fuze launch recoil characteristics, designing the test device to verify the correctness and validity of the research. This paper draws the conclusions that the feasibility of the fuze launch environmental simulation based on the electromagnetic launcher is verified, the trigger position has a great influence on force peak continuity, the problems of low maximum overload peak and short peak duration in the multi-stage coil fuze launch environmental simulation can be effectively solved through adjusting the trigger position, the system has creative and extensive application prospects. 展开更多
关键词 trigger control fuze-recoil simulation electromagnetic launcher
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News event prediction by trigger evolution graph and event segment 被引量:1
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作者 ZHANG Yaru TANG Xijin 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2023年第3期615-626,共12页
Event prediction aims to predict the most possible following event given a chain of closely related context events.Previous methods based on event pairs or the entire event chain may ignore much structural and semanti... Event prediction aims to predict the most possible following event given a chain of closely related context events.Previous methods based on event pairs or the entire event chain may ignore much structural and semantic information.Current datasets for event prediction,naturally,can be used for supervised learning.Event chains are either from document-level procedural action flow,or from news sequences under the same column.This paper leverages graph structure knowledge of event triggers and event segment information for event prediction with general news corpus,and adopts the standard multiple choice narrative cloze task evaluation.The topic model is utilized to extract event chains from the news corpus to deal with training data bottleneck.Based on trigger-guided structural relations in the event chains,we construct trigger evolution graph,and trigger representations are learned through graph convolutional neural network and the novel neighbor selection strategy.Then there are features of two levels for each event,namely,text level semantic feature and trigger level structural feature.We design the attention mechanism to learn the features of event segments derived in term of event major subjects,and integrate relevance between event segments and the candidate event.The most possible next event is picked by the relevance.Experimental results on the real-world news corpus verify the effectiveness of the proposed model. 展开更多
关键词 event prediction trigger evolution graph event segment
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Event-triggered robust guaranteed cost control for two-dimensional nonlinear discrete-time systems 被引量:2
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作者 WANG Sen BU Xuhui LIANG Jiaqi 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2019年第6期1243-1251,共9页
An event-triggered scheme is proposed to solve the problems of robust guaranteed cost control for a class of two-dimensional(2-D)discrete-time systems.Firstly,an eventtriggered scheme is proposed for 2-D discrete-time... An event-triggered scheme is proposed to solve the problems of robust guaranteed cost control for a class of two-dimensional(2-D)discrete-time systems.Firstly,an eventtriggered scheme is proposed for 2-D discrete-time systems with parameter uncertainties and sector nonlinearities.Then,according to the Lyapunov functional method,the sufficient conditions for the existence of event-triggered robust guaranteed cost controller for 2-D discrete-time systems with parameter uncertainties and sector nonlinearities are given.Furthermore,based on the sufficient conditions and the linear matrix inequality(LMI)technique,the problem of designing event-triggered robust guaranteed cost controller is transformed into a feasible solution problem of LMI.Finally,a numerical example is given to demonstrate that,under the proposed event-triggered robust guaranteed cost control,the closed-loop system is asymptotically stable and fewer communication resources are occupied. 展开更多
关键词 event-triggered robust guaranteed cost control two dimensional(2-D)nonlinear system networked control system.
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基于信道质量预测的L2-Trigger触发方法研究
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作者 唐宏 韦世红 +2 位作者 安勇 何鑫 吴中福 《计算机工程与应用》 CSCD 北大核心 2006年第28期18-20,共3页
为了使移动IP可满足实时应用,有文献提出采用二层触发器的方法提前触发三层切换,但是却未能提出明确可行的触发方法,文章通过对移动节点切换过程中信道质量的变换的研究,提出了基于信道质量预测的触发方案,并且通过计算机仿真进行了验证。
关键词 二层触发器 触发方法 信道质量预测
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Event-triggered sampling and fault-tolerant control co-design based on fault diagnosis observer 被引量:1
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作者 QIU Aibing ZHANG Jing +1 位作者 JIANG Bin GU Juping 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2018年第1期176-186,共11页
A co-design scheme of event-triggered sampling mechanism and active fault tolerant control(FTC) is developed. Firstly,a fault diagnosis observer is designed to estimate both the fault and the state simultaneously by u... A co-design scheme of event-triggered sampling mechanism and active fault tolerant control(FTC) is developed. Firstly,a fault diagnosis observer is designed to estimate both the fault and the state simultaneously by using the event-triggered sampled output. Some H∞constraints between the estimation errors and the event-triggered sampling mechanism are established to ensure the estimation accuracy. Then, based on the constraints and the obtained fault information, an event-triggered detector and a static fault tolerant controller are co-designed to guarantee the stability of the faulty system and to reduce the sensor communication cost.Furthermore, the problem of the event detector and dynamic FTC co-design is also investigated. Simulation results of an unstable batch reactor are finally provided to illustrate the effectiveness of the proposed method. 展开更多
关键词 event-triggered sampling fault estimation active fault tolerant control(FTC) CO-DESIGN
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一个用于在线Trigger处理的CAMAC辅助机箱控制器-EBACC
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作者 敬岚 乔卫民 《核电子学与探测技术》 CAS CSCD 北大核心 1992年第5期299-302,共4页
EBACC是我们自行设计的单插宽CAMAC辅助机箱控制器,它可用于重离子物理实验数据获取系统的在线Trigger处理和Pattern分析,并提供数据获取系统和前端电子学系统的快电子学接口信号,内部还设有两个32位的定标器,分别用于总事例计数和已获... EBACC是我们自行设计的单插宽CAMAC辅助机箱控制器,它可用于重离子物理实验数据获取系统的在线Trigger处理和Pattern分析,并提供数据获取系统和前端电子学系统的快电子学接口信号,内部还设有两个32位的定标器,分别用于总事例计数和已获取事例的计数,是我所新研制的数据获取系统的重要插件。 展开更多
关键词 EBACC 数据获取系统 核物理 实验
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Ultrasound Tweezers Trigger Single-Cell Mechanical Dynamics for Cell Mechanophenotyping
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作者 Weiyi Qian Apratim Bajpai +2 位作者 Jie Tong Zijing Zhang Weiqiang Chen 《医用生物力学》 EI CAS CSCD 北大核心 2019年第A01期46-46,共1页
Cells actively modulate mechanobiological circuitry against external perturbations to stabilize whole cell/tissue physiology.The dynamic adaption of cells to mechanical force is critical for cells to perform vital bio... Cells actively modulate mechanobiological circuitry against external perturbations to stabilize whole cell/tissue physiology.The dynamic adaption of cells to mechanical force is critical for cells to perform vital biological functions,from single cell migration to embryonic development.Dysregulation of such dynamics has been associated with pathophysiological conditions in cardiovascular diseases,cancer,aging,and developmental disorders[1].Therefore,a direct understanding of cell’s biomechanical adaptive/maladaptive behaviors and the trigger factors causing the transformation of healthy adaption to maladaptation can help reveal the regulatory role of single cell mechanosensitive dynamics in the progression of various degenerative diseases and aging.However,current efforts for uncovering fundamental associations between disease and cell architecture have been focusing on'static'measurements of biophysical properties,which is limited by the requirement of large sample sizes to obtain statistically significant data.We therefore developed a single and highly integrated platform with mechanical stimulation and fine spatiotemporal sensing functions to probe the single cell mechanical dynamics at subcellular level to determine cell’s mechanophenotypes in healthy and disease conditions.We developed an integrated micromechanical system composed of an’ultrasound tweezer’stimulator[2]and a PDMS micropillar array [3] cellular force sensor to in situ noninvasively probe and monitor single cell mechanical dynamics.Vascular smooth muscle cells(VSMCs)from healthy mouse and mouse with induced abdominal aorta aneurysm(AAA)were used for cell mechanobiological study.An ultrasound transducer(V312-SM,Olympus)was used to generate ultrasound pulses to excite lipid-encapsulated microbubbles(Targeson)binding to cell membrane through an RGD-integrin linkage to apply a transient nanonewton force to VSMCs seeded on the PDMS micropillar array.PDMS micropillar array was fabricated and functionalized as previously described [3] and acts as the mechanical force sensor in our platform.Upon a 1 HZ and 10-second ultrasound stimulation,calcium influx was clearly detected in both healthy and AAA-VSMCs by using the fluo-4 calcium sensor,suggesting the microbubble-integrin-actin cytoskeleton(CSK)linkage can serve as a mechanosensory to sense the ultrasound stimulation.We then examined how healthy and AAA VSMCs would exhibit adaptions to mechanical stimulation at a global cellular scale.After the onset of a 10-second ultrasound stimulation,control and AAA-VSMCs displayed distinct dynamics of CSK tension within 30 mins,in which the CSK tension of healthy VSMCs increased within the reinforcement period(0-5 min)and restored to their ground state with the relaxation period(5-10 min);yet AAA-VSMCs displayed compromised dynamics of such CSK tension upon calcium influx.Quantitative analysis and theoretical modelling revealed the critical roles of myosin motor contraction,F-actin filament polymerization in regulating cell mechanosensitive dynamics in response to a transient mechanical perturbation.The distinct force and CSK dynamics in healthy and AAA conditions indicates that the force-dependent CSK molecular kinetics is a critical factor governing the distinct mechanosensitive dynamics of cells under pathologically dysfunctional conditions.Our results reveal that the mechanical adaptive process of cells to mechanical stimulus can measure the cellular mechanobiological phenotypes featured in both pathologically healthy and diseased context.We demonstrated that an altered mechanobiological phenotype,i.e.AAA-VSMCs with distinct actomyosin-CSK properties potentiates a mechanical maladaptation that reflects progressive accumulation of cellular damage and dysfunction.This may further reveal the pathogenic contexts and their physical mediators featuring biophysical dysregulation in cardiovascular diseases. 展开更多
关键词 AAA ULTRASOUND TWEEZERS trigger SINGLE-CELL Mechanical Dynamics CELL Mechanophenotyping
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Testing of Lightning Protective System of a Residential Structure: Comparison of Data Obtained in Rocket-triggered Lightning and Current Surge Generator Experiments
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作者 G. Maslowski V.A. Rakov +9 位作者 S. Wyderka J. Bajorek B.A. DeCarlo J. Jerauld G.H. Schnetzer J. Schoene M.A. Uman K.J. Rambo D.M. Jordan W. Krata 《高电压技术》 EI CAS CSCD 北大核心 2008年第12期2575-2582,共8页
We present a comparison of data obtained during testing of lightning protective system of a residential structure in rocket-triggered lightning experiment at the International Center for Lightning Research and Testing... We present a comparison of data obtained during testing of lightning protective system of a residential structure in rocket-triggered lightning experiment at the International Center for Lightning Research and Testing(ICLRT)at Camp Blanding,Florida,and current surge generator experiment at Rzeszow University of Technology in Poland.Three different configurations of LPS were tested in Poland with the dc grounding resistances of the entire system 4.09 Ω(LPS 1a),1.65 Ω(LPS 1b),and 2.88 Ω(LPS 2).For LPS 1a with three ground rods the value of the peak current entering the electrical circuit neutral was about 56% of the injected current peak,and for LPS 1b with two additional ground rods and two 5 m long buried horizontal conductors it was about 16%.For LPS 2 with five ground rods interconnected by a buried loop conductor this ratio was 21%.The current waveshapes in the ground rods differed from the injected current waveshapes and the current waveshapes in other parts of the test system,especially,for poorer-grounding LPS 1a.The surge-generator results are consistent with those of triggered-lightning experiments at Camp Blanding,Florida(DeCarlo et al.,2008 [2]). 展开更多
关键词 居民区 雷电保护系统 试验 电流冲击发生器
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干旱胁迫下植被生产力与冠层结构易损性的非一致性评估 被引量:1
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作者 张璐 畅建霞 +2 位作者 杨贵斌 郭爱军 王义民 《农业工程学报》 北大核心 2025年第6期145-153,共9页
频繁的干旱事件已对植被正常生长与生态系统稳定构成威胁。为解析干旱对植被影响的复杂性,该研究基于Copula模型,利用归一化植被指数、总初级生产力和标准化降水蒸散发指数,构建了气象干旱胁迫下植被生产力与冠层结构损失的条件概率模型... 频繁的干旱事件已对植被正常生长与生态系统稳定构成威胁。为解析干旱对植被影响的复杂性,该研究基于Copula模型,利用归一化植被指数、总初级生产力和标准化降水蒸散发指数,构建了气象干旱胁迫下植被生产力与冠层结构损失的条件概率模型,并运用偏最小二乘路径模型,探讨了植被对干旱响应的驱动因子。结果表明,1982—2018年长江流域植被生产力、冠层结构对气象干旱的滞后响应在时间维和空间维呈现出非一致性特征。时间上,植被生产力对气象干旱的响应时间较冠层结构更长;空间上,汉江流域和长江中下游干流区植被生产力易损性高,而金沙江流域和长江干流区间冠层结构易损性高。不同类型植被的易损性不同,水田和常绿阔叶林的生产力损失概率较高,分别为21.05%、17.26%,草地和常绿针叶林的冠层结构损失概率更大,分别为36.35%、35.73%。此外,植被生产力与冠层结构的关键环境影响因子不同,前者主要受控于冠层结构和土壤水分,后者则对海拔和气候因子更为敏感。研究成果有助于深入了解干旱对植被的影响,进而为生态系统管理与保护提供重要的科学依据。 展开更多
关键词 植被生产力 冠层结构 植被响应 触发阈值 长江流域
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基于模型预测控制的无人车编队避障方法 被引量:4
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作者 张硕 吴雨洋 +3 位作者 汪洋 王一全 崔星 宿玉康 《北京理工大学学报》 EI CAS 北大核心 2025年第1期34-41,共8页
为研究障碍物环境下基于模型预测控制的无人车编队避障方法,建立了包含虚拟智能体状态的编队避障函数,使避障问题容易用优化方法求解.在无人车编队内部引入优先级策略实现编队内部避碰,并通过动态事件触发机制减小无人车之间通讯带宽占... 为研究障碍物环境下基于模型预测控制的无人车编队避障方法,建立了包含虚拟智能体状态的编队避障函数,使避障问题容易用优化方法求解.在无人车编队内部引入优先级策略实现编队内部避碰,并通过动态事件触发机制减小无人车之间通讯带宽占用.对该方法进行了计算机仿真验证,在给定多边形障碍物环境下,使用领导者-追随者架构执行编队行驶任务,并借助事件触发器实现间歇通讯.结果表明,相较于传统方法,所设计的编队控制器能够提高带宽约束下无人车编队行驶安全性. 展开更多
关键词 编队控制 模型预测控制 动态事件触发机制 无人车避障
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事件触发下多移动机器人抗干扰固定时间预定性能编队 被引量:1
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作者 王健安 闫慧娴 +3 位作者 张君如 张捷 李明杰 赵志诚 《自动化学报》 北大核心 2025年第7期1703-1714,共12页
考虑多移动机器人编队系统存在模型参数不确定、未知扰动和有限通信资源问题,提出一种固定时间预定性能的事件触发编队控制方法.首先,设计新的固定时间干扰观测器以精确估计系统的复合扰动.其次,基于干扰观测器、预定性能函数、反步法... 考虑多移动机器人编队系统存在模型参数不确定、未知扰动和有限通信资源问题,提出一种固定时间预定性能的事件触发编队控制方法.首先,设计新的固定时间干扰观测器以精确估计系统的复合扰动.其次,基于干扰观测器、预定性能函数、反步法和固定时间理论,并考虑通信资源受限问题,设计时变阈值事件触发的固定时间预定性能编队控制器,使得编队误差在固定时间内收敛且满足预定性能要求.所提出的触发机制可减少因控制器和执行器频繁通信造成的网络资源浪费,且无Zeno行为发生.最后,通过对三个移动机器人进行编队仿真,验证了所提方法的有效性. 展开更多
关键词 多移动机器人 编队控制 干扰观测器 预定性能 固定时间 事件触发
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血浆可溶性髓样细胞触发受体-1、类固醇激素与肺结核患者疾病严重程度的相关性 被引量:1
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作者 杨颖乔 李燕 徐旭燕 《中国感染与化疗杂志》 北大核心 2025年第1期1-6,共6页
目的探讨基线血浆可溶性髓样细胞触发受体(sTREM)-1、类固醇激素[皮质醇和脱氢表雄酮(DHEA)]和免疫内分泌标志物与肺结核(PTB)患者疾病严重程度的相关性。方法在2020年3月至2022年5月招募了76例PTB患者和78名健康对照者作为研究对象,比... 目的探讨基线血浆可溶性髓样细胞触发受体(sTREM)-1、类固醇激素[皮质醇和脱氢表雄酮(DHEA)]和免疫内分泌标志物与肺结核(PTB)患者疾病严重程度的相关性。方法在2020年3月至2022年5月招募了76例PTB患者和78名健康对照者作为研究对象,比较健康者、PTB患者的血浆sTREM-1水平,并分析血浆s TREM-1与C反应蛋白(CRP)、白细胞介素(IL)-6和干扰素(IFN)-γ、红细胞沉降率(ESR)、类固醇激素(皮质醇和DHEA)和外周血单核细胞炎性转录物(IL-6、IFN-γ)的关系。结果与对照组比较,PTB患者中sTREM-1、CRP、ESR、IL-6、IFN-γ、皮质醇、皮质醇/DHEA显著升高(P<0.05),而DHEA显著降低(P<0.05)。且重度PTB组sTREM-1、ESR水平高于轻、中度PTB组。经Spearman相关性分析,在所有患者中,s TREM与CRP呈显著正相关(P<0.05)。而只有在重度PTB患者中,sTREM-1与皮质醇/DHEA呈显著正相关(P<0.05),与DHEA呈显著负相关(P<0.05)。结论血浆sTREM-1水平较高可能是导致PTB患者晚期疾病特有的免疫内分泌失衡持续存在的一个重要因素。 展开更多
关键词 可溶性髓样细胞触发受体-1 肺结核 重度肺结核 免疫内分泌标志物
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