Purpose:The present work examines the associations of dietary habits,sedentarism,physical activity(PA)levels and sleep habits,with thyroid function in young euthyroid adults.Methods:A total of 105 young euthyroid adul...Purpose:The present work examines the associations of dietary habits,sedentarism,physical activity(PA)levels and sleep habits,with thyroid function in young euthyroid adults.Methods:A total of 105 young euthyroid adults participated in this cross-sectional study.Thyroid function was determined in fasting conditions(>6 h).Dietary habits were measured by a food frequency questionnaire and three non-consecutive 24 h recalls,and different dietary intake and patterns were then estimated.The time spent in sedentary,PA levels and sleep habits were objectively measured using a wrist-worn accelerometer.Results:Energy and carbohydrate intake were positively associated with thyroid stimulating hormone(TSH)(β=0.222;R^(2)=0.102;P=0.022 andβ=0.425;R^(2)=0.129;P=0.007,respectively)whereas fat intake was negatively associated with TSH(β=-0.428;R^(2)=0.137;P=0.004).Energy intake was also positively associated with free triiodothyronine(β=0.277;R^(2)=0.137;P=0.004).Further,adherence to the Mediterranean diet was negatively related to TSH and free thyroxine(FT4)(β=-0.221;R^(2)=0.113;P=0.020 andβ=-0.268;R^(2)=0.071;P=0.007,respectively).Vigorous-intensity and overall PA were negatively associated with FT4(β=-0.227;R^(2)=0.052;P=0.022 andβ=-0.204;R^(2)=0.042;P=0.041,respectively).In contrast,no associations were found between sleep parameters and thyroid function.Conclusions:Lifestyle factors such as dietary intake and PA levels seems to be related to thyroid function even in young euthyroid adults.展开更多
目的探讨低功率电刀切皮联合术后皮下整形减张缝合减轻开放性甲状腺手术颈部瘢痕的临床效果。方法选择接受开放性甲状腺手术患者383例,根据手术器械和缝合方式不同,分为A、B、C三组。其中,A组126例,予传统手术刀切皮+术后传统皮下间断缝...目的探讨低功率电刀切皮联合术后皮下整形减张缝合减轻开放性甲状腺手术颈部瘢痕的临床效果。方法选择接受开放性甲状腺手术患者383例,根据手术器械和缝合方式不同,分为A、B、C三组。其中,A组126例,予传统手术刀切皮+术后传统皮下间断缝合;B组132例,予低功率电刀切皮+术后传统皮下间断缝合;C组125例,予低功率电刀切皮+术后皮下整形减张缝合。比较三组围手术期相关指标[手术时间、术中出血量、术后引流量、住院时间以及术后12、36 h疼痛视觉模拟评分(VAS)]、切口并发症情况(切口感染、皮下积液或血肿、切口脂肪液化等);术后1、6、12个月,采用温哥华瘢痕评定量表(VSS)及患者瘢痕评估量表(PSAS)评分评估颈部瘢痕程度。结果三组手术时间、术中出血量、术后引流量及术后12、36 h VAS评分和住院时间比较差异均无统计学意义(P均>0.05)。三组切口感染、皮下血肿、脂肪液化等术后切口并发症的发生率比较差异无统计学意义(P>0.05)。三组术后1、6、12个月VSS评分和PSAS评分均逐渐降低(P均<0.05);C组术后1、6、12个月VSS评分和PSAS评分均低于A、B组同期(P均<0.05)。结论低功率电刀切皮联合术后皮下整形减张缝合能够减轻开放性甲状腺手术颈部瘢痕,方法简单易行,安全性高。展开更多
基金funded by the Spanish Ministry of Economy and Competitiveness via the Fondo de Investigación Sanitaria del Instituto de Salud CarlosⅢ(PI13/01393)by the Retos de la Sociedad program(DEP2016-79512-R)+7 种基金European Regional Development Funds(ERDF)the Spanish Ministry of Education(FPU13/04365 and FPU19/01609)the Fundación Iberoamericana de Nutrición(FINUT)the Redes Temáticas de Investigación Cooperativa RETIC(Red SAMID RD16/0022)the Astra Zeneca Health Care Foundationthe University of Granada Plan Propio de Investigación 2016-Excellence actions:Unit of Excellence on Exercise and Health(UCEES)-and Plan Propio de Investigación 2018-the Programa Contratos-Puente and Contratos Perfeccionamiento de Doctoresthe Junta de Andalucía,Consejería de Conocimiento,Investigacióny Universidades(ERDF,ref.SOMM17/6107/UGR)the Fundación Alfonso Martín Escudero(grant awarded to GSD)。
文摘Purpose:The present work examines the associations of dietary habits,sedentarism,physical activity(PA)levels and sleep habits,with thyroid function in young euthyroid adults.Methods:A total of 105 young euthyroid adults participated in this cross-sectional study.Thyroid function was determined in fasting conditions(>6 h).Dietary habits were measured by a food frequency questionnaire and three non-consecutive 24 h recalls,and different dietary intake and patterns were then estimated.The time spent in sedentary,PA levels and sleep habits were objectively measured using a wrist-worn accelerometer.Results:Energy and carbohydrate intake were positively associated with thyroid stimulating hormone(TSH)(β=0.222;R^(2)=0.102;P=0.022 andβ=0.425;R^(2)=0.129;P=0.007,respectively)whereas fat intake was negatively associated with TSH(β=-0.428;R^(2)=0.137;P=0.004).Energy intake was also positively associated with free triiodothyronine(β=0.277;R^(2)=0.137;P=0.004).Further,adherence to the Mediterranean diet was negatively related to TSH and free thyroxine(FT4)(β=-0.221;R^(2)=0.113;P=0.020 andβ=-0.268;R^(2)=0.071;P=0.007,respectively).Vigorous-intensity and overall PA were negatively associated with FT4(β=-0.227;R^(2)=0.052;P=0.022 andβ=-0.204;R^(2)=0.042;P=0.041,respectively).In contrast,no associations were found between sleep parameters and thyroid function.Conclusions:Lifestyle factors such as dietary intake and PA levels seems to be related to thyroid function even in young euthyroid adults.
文摘目的探讨低功率电刀切皮联合术后皮下整形减张缝合减轻开放性甲状腺手术颈部瘢痕的临床效果。方法选择接受开放性甲状腺手术患者383例,根据手术器械和缝合方式不同,分为A、B、C三组。其中,A组126例,予传统手术刀切皮+术后传统皮下间断缝合;B组132例,予低功率电刀切皮+术后传统皮下间断缝合;C组125例,予低功率电刀切皮+术后皮下整形减张缝合。比较三组围手术期相关指标[手术时间、术中出血量、术后引流量、住院时间以及术后12、36 h疼痛视觉模拟评分(VAS)]、切口并发症情况(切口感染、皮下积液或血肿、切口脂肪液化等);术后1、6、12个月,采用温哥华瘢痕评定量表(VSS)及患者瘢痕评估量表(PSAS)评分评估颈部瘢痕程度。结果三组手术时间、术中出血量、术后引流量及术后12、36 h VAS评分和住院时间比较差异均无统计学意义(P均>0.05)。三组切口感染、皮下血肿、脂肪液化等术后切口并发症的发生率比较差异无统计学意义(P>0.05)。三组术后1、6、12个月VSS评分和PSAS评分均逐渐降低(P均<0.05);C组术后1、6、12个月VSS评分和PSAS评分均低于A、B组同期(P均<0.05)。结论低功率电刀切皮联合术后皮下整形减张缝合能够减轻开放性甲状腺手术颈部瘢痕,方法简单易行,安全性高。
