The quantitative anaesthesia assessment technique was used to evaluate the effectiveness of ketamine, ketamine-xylidinothiazoline in rhesus monkey. Total 20 healthy adult rhesus monkeys were divided into two groups an...The quantitative anaesthesia assessment technique was used to evaluate the effectiveness of ketamine, ketamine-xylidinothiazoline in rhesus monkey. Total 20 healthy adult rhesus monkeys were divided into two groups and anaesthetized using either intramuscular （IM） ketamine （20 mg·kg^-1） or ketamine （5 mg·kg^-1 IM） and xylidinothiazoline （1 mg·kg^-1 IM）. During anaesthesia rectal temperature, respiratory rate, heart rate, saturation of blood oxygen and blood pressure were recorded. The degree of sedation, analgesia, muscle relaxation were monitored either. The results showed that ketamine alone did not produce adequate anaesthesia, and the combination of xylidinothiazoline and ketamine provided adequate anesthesia for rhesus monkeys with no significant side effects and little effects on respiration and circulation.展开更多
文摘The quantitative anaesthesia assessment technique was used to evaluate the effectiveness of ketamine, ketamine-xylidinothiazoline in rhesus monkey. Total 20 healthy adult rhesus monkeys were divided into two groups and anaesthetized using either intramuscular （IM） ketamine （20 mg·kg^-1） or ketamine （5 mg·kg^-1 IM） and xylidinothiazoline （1 mg·kg^-1 IM）. During anaesthesia rectal temperature, respiratory rate, heart rate, saturation of blood oxygen and blood pressure were recorded. The degree of sedation, analgesia, muscle relaxation were monitored either. The results showed that ketamine alone did not produce adequate anaesthesia, and the combination of xylidinothiazoline and ketamine provided adequate anesthesia for rhesus monkeys with no significant side effects and little effects on respiration and circulation.
