Psoriasis is a chronic,refractory,inflammatory skin disease that occurs in young adults.The traditional animal model cannot simulate the skin characteristics of patients with psoriasis effectively,so it is difficult t...Psoriasis is a chronic,refractory,inflammatory skin disease that occurs in young adults.The traditional animal model cannot simulate the skin characteristics of patients with psoriasis effectively,so it is difficult to be used for in-depth study of psoriasis mechanism.Immortalized human epidermal cells(HaCaT) is a non-tumor,immortalized human epidermal cell which is widely used in the study of dermatosis.HaCaT cells are the best choice for the study of psoriasis mechanism because their immu.nological characteristics and reproductive ability are coincide with the pathological features of psoriasis.This article reviews the specific methods such as establishment of cell method,cytokine and chemo.kine analysisin the pathogenesis study of psoriasis based on HaCaT cells,hoping to provide some thoughts for drug′s pharmacological activity research.展开更多
Epigenetic Methods in Neuroscience Research(ISBN:978-1-4939-2753-1,e Book ISBN:978-1-4939-2754-8)was published by Springer in 2016.The editor of this book is Nina N.Karpova,Neuroscience Center,University of Helsinki.T...Epigenetic Methods in Neuroscience Research(ISBN:978-1-4939-2753-1,e Book ISBN:978-1-4939-2754-8)was published by Springer in 2016.The editor of this book is Nina N.Karpova,Neuroscience Center,University of Helsinki.This volume presents state-of-the-art methods for reliable detection of epigenetic changes in the nervous system.Epigenetic guides readers through methods for the analyses of chromatin remodeling,transposable elements,展开更多
Epilepsy Towards the Next Decade(ISBN:978-3-319-12282-3,eBook ISBN:978-3-319-12283-0)was published by Springer International Publishing in 2015.The editor of this book is Pasquale Striano,Pediatric Neurology and Muscu...Epilepsy Towards the Next Decade(ISBN:978-3-319-12282-3,eBook ISBN:978-3-319-12283-0)was published by Springer International Publishing in 2015.The editor of this book is Pasquale Striano,Pediatric Neurology and Muscular Diseases Unit,University of Genoa.This volume is a comprehensive collection of the most recent knowledge on the biological bases of various kinds of展开更多
Association mapping(as opposed to population mapping) is becoming more important in establishing associations between a phenotype and a genotype.The major advantage of association mapping,
本研究基于Web of Science 数据库,运用文本挖掘法,考察了2001—2024年SSCI来源期刊发表的725篇商务英语研究论文中的热点话题、发展脉络、代表性理论和研究方法,梳理了国外商务英语的研究进展。研究发现,国外商务英语研究主要聚焦五大...本研究基于Web of Science 数据库,运用文本挖掘法,考察了2001—2024年SSCI来源期刊发表的725篇商务英语研究论文中的热点话题、发展脉络、代表性理论和研究方法,梳理了国外商务英语的研究进展。研究发现,国外商务英语研究主要聚焦五大主题,即商务英语教学、企业对外话语、企业内部沟通、世界通用语和商务话语语言特征与计量分析;发展脉络呈现五波发展浪潮,包括商务语境中的话语策略(2001—2005)、跨文化商务交流与基于需求的教学(2006—2010)、世界通用语与企业话语治理(2011—2015)、跨国公司话语与专业化教学(2016—2020)、数字语境与数据驱动下的商务话语与教学(2021—2024)。代表性理论包括跨文化商务交际、互文性与体裁分析和修辞学理论。在研究方法上,以实证研究方法为主,非实证研究方法多为观点总结和理论建构。希望本研究有助于厘清国际商务英语研究脉络,并对国内相关研究及教学具有一定启示作用。展开更多
文摘Psoriasis is a chronic,refractory,inflammatory skin disease that occurs in young adults.The traditional animal model cannot simulate the skin characteristics of patients with psoriasis effectively,so it is difficult to be used for in-depth study of psoriasis mechanism.Immortalized human epidermal cells(HaCaT) is a non-tumor,immortalized human epidermal cell which is widely used in the study of dermatosis.HaCaT cells are the best choice for the study of psoriasis mechanism because their immu.nological characteristics and reproductive ability are coincide with the pathological features of psoriasis.This article reviews the specific methods such as establishment of cell method,cytokine and chemo.kine analysisin the pathogenesis study of psoriasis based on HaCaT cells,hoping to provide some thoughts for drug′s pharmacological activity research.
文摘Epigenetic Methods in Neuroscience Research(ISBN:978-1-4939-2753-1,e Book ISBN:978-1-4939-2754-8)was published by Springer in 2016.The editor of this book is Nina N.Karpova,Neuroscience Center,University of Helsinki.This volume presents state-of-the-art methods for reliable detection of epigenetic changes in the nervous system.Epigenetic guides readers through methods for the analyses of chromatin remodeling,transposable elements,
文摘Epilepsy Towards the Next Decade(ISBN:978-3-319-12282-3,eBook ISBN:978-3-319-12283-0)was published by Springer International Publishing in 2015.The editor of this book is Pasquale Striano,Pediatric Neurology and Muscular Diseases Unit,University of Genoa.This volume is a comprehensive collection of the most recent knowledge on the biological bases of various kinds of
文摘Association mapping(as opposed to population mapping) is becoming more important in establishing associations between a phenotype and a genotype.The major advantage of association mapping,
文摘本研究基于Web of Science 数据库,运用文本挖掘法,考察了2001—2024年SSCI来源期刊发表的725篇商务英语研究论文中的热点话题、发展脉络、代表性理论和研究方法,梳理了国外商务英语的研究进展。研究发现,国外商务英语研究主要聚焦五大主题,即商务英语教学、企业对外话语、企业内部沟通、世界通用语和商务话语语言特征与计量分析;发展脉络呈现五波发展浪潮,包括商务语境中的话语策略(2001—2005)、跨文化商务交流与基于需求的教学(2006—2010)、世界通用语与企业话语治理(2011—2015)、跨国公司话语与专业化教学(2016—2020)、数字语境与数据驱动下的商务话语与教学(2021—2024)。代表性理论包括跨文化商务交际、互文性与体裁分析和修辞学理论。在研究方法上,以实证研究方法为主,非实证研究方法多为观点总结和理论建构。希望本研究有助于厘清国际商务英语研究脉络,并对国内相关研究及教学具有一定启示作用。
