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Emodin suppresses LPS-induced proinflammatory responses and nuclear factor-B activation by disruption of lipid rafts and TLR-4 recruitment in endothelial cells
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作者 Guoquan MENG,Yiyao LIU,Youguang Luo,Hong Yang(Department of Biophysics,School of Life Science and Technology,University of Electronic Science and Technology of China,Chengdu 610054) 《医用生物力学》 EI CAS CSCD 2009年第S1期122-122,共1页
Emodin [1,3,8-Trihydroxy-6-methylanthraquinone] has been reported to exhibit vascular anti-inflammatory properties.However,the relevant anti-inflammatory mechanisms are not well understood.The present study was design... Emodin [1,3,8-Trihydroxy-6-methylanthraquinone] has been reported to exhibit vascular anti-inflammatory properties.However,the relevant anti-inflammatory mechanisms are not well understood.The present study was design to explore the molecular target(s) of emodin 展开更多
关键词 TLR Emodin suppresses LPS-induced proinflammatory responses and nuclear factor-B activation by disruption of lipid rafts and TLR-4 recruitment in endothelial cells HUVECs
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用AP-N_1(或ABR波I)潜伏期检测响度重振
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作者 于黎明 姜泗长 《中华耳科学杂志》 CSCD 2003年第1期38-40,共3页
本文对50例平坦型感音神经性聋病人用声反射阈以及AP-N_1潜伏期检查响度重振进行了分析,结果显示:声反射阈重振阳性率为76%,纯音听阈与声反射阈阳性率的关系为:随着听阈的增高声反射阈阳性率下降;耳蜗电图在高声强时AP-N_1潜伏期完全... 本文对50例平坦型感音神经性聋病人用声反射阈以及AP-N_1潜伏期检查响度重振进行了分析,结果显示:声反射阈重振阳性率为76%,纯音听阈与声反射阈阳性率的关系为:随着听阈的增高声反射阈阳性率下降;耳蜗电图在高声强时AP-N_1潜伏期完全在正常范围的占56%,若以患耳与正常耳在同一阈上dB数比较,则100%小于正常耳,显示重振阳性。如果两指标结合检测,响度重振阳性率也明显提高。我们认为用AP-N_1潜伏期检测响度重振方法可行、理论依据充分,且用它检测响度重振的阳性率明显高于声反射阈。 展开更多
关键词 recruitment Acoustic reflex threshold (ART) Electrocochleargragh (ECochG) Auditory brainstem response (ABR)
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