Solidified floating organic drop microextraction(SFODME)in combination with high performance liquid chromatography was used for separation/preconcentration and determination of carbamazepine(CBZ)in human plasma and ur...Solidified floating organic drop microextraction(SFODME)in combination with high performance liquid chromatography was used for separation/preconcentration and determination of carbamazepine(CBZ)in human plasma and urine samples.Parameters that affect the extraction efficiency such as the type and volume of extraction solvent,ionic strength,sodium hydroxide concentration,stirring rate,sample volume and extraction time,were investigated and optimized.Under the optimum conditions(extraction solvent,40μL of 1-undecanol;sodium hydroxide concentration,1 mol/L;temperature,50℃;stirring speed,400 r/min;sample volume,8 mL;sodium chloride concentration,3%(w/v)and extraction time,60 min)the calibration curve was found to be linear in the mass concentration range of 0.4-700.0μg/L.The limit of detection(LOD)was 0.1μg/L and the relative standard deviation(RSD)for six replicate extraction and determination of carbamazepine at 100μg/L level was found to be 4.1%.The method was successfully applied to the determination of CBZ in human plasma and urine samples.展开更多
Hybrid nanomaterials have attracted considerable interest in environmental science,analytical chemistry and atomic spectroscopy.In the present study,a column solid phase extractioo procedure was developed for the sepa...Hybrid nanomaterials have attracted considerable interest in environmental science,analytical chemistry and atomic spectroscopy.In the present study,a column solid phase extractioo procedure was developed for the separation and preconcentration of indium in various matrixes by using hybrid nanomaterial B_2O_3/ZrO_2(HNMBZ).Various experimental and analytical parameters such as sample solution pH,sample solution volume,flow rate of sample solution and eluent,volume and concentration of eluent aod amount of HNMBZ,effect of common matrix ions and capacity of sorbent were investigated.The adsorbed metal ions on HNMBZ were eluted with 6mL of 1mol·L^(-1 )HNO_3solutions and their concentrations were determined by high-resolution continuum source flame atomic absorption spectrometry(HR-CS FAAS).Under the optimized conditions,detection limits for indium for 3pixels and 5pixels were found as 0.20and 0.16μg·L^(-1),respectively.The accuracy of the procedure was checked by spiked water samples.The developed procedure was successfully applied to real samples for the separation and determination of indium.展开更多
Interest in preconcentration techniques for the determination of metals at ultratrace levels still continues increasingly because of some disadvantages of flameless atomic absorption spectrometry as well as the high c...Interest in preconcentration techniques for the determination of metals at ultratrace levels still continues increasingly because of some disadvantages of flameless atomic absorption spectrometry as well as the high costs of other sensitive methods in compared to flame atomic absorption spectrometry.In this study,thiol-containing sulfonamide resin was synthesized,characterized and applied as a new sorption material for solid phase extraction of nickel in drinking water samples.After preconcentration procedure,flame atomic absorption spectrometry was used for determinations.Optimum parameters were found to be pH=3.2,contact time=20 min and eluate volume=3 mL.The limit of detection was found to be 0.75 ng·mL-1.The synthesized resin exhibits the superiority in compared to the other adsorption reagents because of the fact that there is no necessity of any complexing reagent,high sorption capacity as well as the relatively fast extraction rate.The Ni concentrations in the studied 21 kind of water samples were found to be in the range of BDL-4.0 ng·mL-1.展开更多
文摘Solidified floating organic drop microextraction(SFODME)in combination with high performance liquid chromatography was used for separation/preconcentration and determination of carbamazepine(CBZ)in human plasma and urine samples.Parameters that affect the extraction efficiency such as the type and volume of extraction solvent,ionic strength,sodium hydroxide concentration,stirring rate,sample volume and extraction time,were investigated and optimized.Under the optimum conditions(extraction solvent,40μL of 1-undecanol;sodium hydroxide concentration,1 mol/L;temperature,50℃;stirring speed,400 r/min;sample volume,8 mL;sodium chloride concentration,3%(w/v)and extraction time,60 min)the calibration curve was found to be linear in the mass concentration range of 0.4-700.0μg/L.The limit of detection(LOD)was 0.1μg/L and the relative standard deviation(RSD)for six replicate extraction and determination of carbamazepine at 100μg/L level was found to be 4.1%.The method was successfully applied to the determination of CBZ in human plasma and urine samples.
基金the Scientific and Technological Research Council of Turkey(TUBITAK Grants no.110T111,214Z221)
文摘Hybrid nanomaterials have attracted considerable interest in environmental science,analytical chemistry and atomic spectroscopy.In the present study,a column solid phase extractioo procedure was developed for the separation and preconcentration of indium in various matrixes by using hybrid nanomaterial B_2O_3/ZrO_2(HNMBZ).Various experimental and analytical parameters such as sample solution pH,sample solution volume,flow rate of sample solution and eluent,volume and concentration of eluent aod amount of HNMBZ,effect of common matrix ions and capacity of sorbent were investigated.The adsorbed metal ions on HNMBZ were eluted with 6mL of 1mol·L^(-1 )HNO_3solutions and their concentrations were determined by high-resolution continuum source flame atomic absorption spectrometry(HR-CS FAAS).Under the optimized conditions,detection limits for indium for 3pixels and 5pixels were found as 0.20and 0.16μg·L^(-1),respectively.The accuracy of the procedure was checked by spiked water samples.The developed procedure was successfully applied to real samples for the separation and determination of indium.
文摘Interest in preconcentration techniques for the determination of metals at ultratrace levels still continues increasingly because of some disadvantages of flameless atomic absorption spectrometry as well as the high costs of other sensitive methods in compared to flame atomic absorption spectrometry.In this study,thiol-containing sulfonamide resin was synthesized,characterized and applied as a new sorption material for solid phase extraction of nickel in drinking water samples.After preconcentration procedure,flame atomic absorption spectrometry was used for determinations.Optimum parameters were found to be pH=3.2,contact time=20 min and eluate volume=3 mL.The limit of detection was found to be 0.75 ng·mL-1.The synthesized resin exhibits the superiority in compared to the other adsorption reagents because of the fact that there is no necessity of any complexing reagent,high sorption capacity as well as the relatively fast extraction rate.The Ni concentrations in the studied 21 kind of water samples were found to be in the range of BDL-4.0 ng·mL-1.
