Optimal activation of T cells requires at least 2signals. Signal one is generated by interactionsbetween T cell receptor and antigenic peptide-majorhistocompatibility complex on antigen-presentingcells. Signal two is ...Optimal activation of T cells requires at least 2signals. Signal one is generated by interactionsbetween T cell receptor and antigenic peptide-majorhistocompatibility complex on antigen-presentingcells. Signal two is delivered by co-stimulatory ligandson antigen-presenting cells to their receptors on展开更多
Aluminum is an important basic raw material for national economic development.The alumina industry has been expanding rapidly due to the increasing demand for aluminum.Bauxite residue is a highly alkaline solid by-pro...Aluminum is an important basic raw material for national economic development.The alumina industry has been expanding rapidly due to the increasing demand for aluminum.Bauxite residue is a highly alkaline solid by-product generated when alumina is extracted from bauxite ore in alumina refineries[1,2].展开更多
目的评估中文版患者报告结局测量信息系统(Patient Reported Outcome Measurement Information System,PROMIS)癌症特异性抑郁项目库的心理测量学属性,构建计算机自适应测试版本(PROMIS Cancer Depression CAT),并评价其效果。方法采用...目的评估中文版患者报告结局测量信息系统(Patient Reported Outcome Measurement Information System,PROMIS)癌症特异性抑郁项目库的心理测量学属性,构建计算机自适应测试版本(PROMIS Cancer Depression CAT),并评价其效果。方法采用便利抽样法选取2020年11月—2021年7月在上海2所三级甲等医院的648例癌症患者作为研究对象。在心理测量学评估中,首先基于Rasch模型采用残差的主成分分析、条目残差相关系数、条目特征曲线检验PROMIS癌症特异性抑郁项目库的单维性、局部独立性、单调性假设;其次,通过Rasch模型中的选项特征曲线对选项进行拟合,采用Rasch模型中的Infit MNSQ、Outfit MNSQ、难度参数对每个条目进行拟合;最后,将经过校准后的项目库内容作为PROMIS Cancer Depression CAT的题库,采用Post-hoc模拟方法评价PROMIS Cancer Depression CAT的测量效率和准确性。结果PROMIS癌症特异性抑郁项目库由测试解释的经验方差为68.6%,条目之间的残差相关值都小于0.70,条目特征曲线是单调递增曲线。PROMIS癌症特异性抑郁项目库中的5个选项的峰值均未被相邻选项的特征曲线覆盖,5个选项之间阈值的间隔均大于1且小于5,条目的Infit MNSQ值为[0.54,1.49],Outfit MNSQ值为[0.55,1.49],选项和条目的拟合均在理想范围内,可作为构建PROMIS Cancer Depression CAT的项目库。Post-hoc模拟执行CAT的θ值与整个项目库的θ值相关系数为0.964,选择的平均使用条目数为6.348个。结论中文版PROMIS癌症特异性抑郁项目库满足单维性、局部独立性以及单调性假设,可以用来构建PROMIS Cancer Depression CAT。基于PROMIS癌症特异性抑郁项目库参数构建的计算机自适应测试版本能够高效、准确地测量癌症患者的抑郁水平。展开更多
In order to forecast promising technologies in the field of next generation mobile communication, various patent indicators were analyzed such as citation per patent, patent family information, patent share, increase ...In order to forecast promising technologies in the field of next generation mobile communication, various patent indicators were analyzed such as citation per patent, patent family information, patent share, increase rate, and patent activity. These indicators were quantified into several indexes and then integrated into an evaluation score to provide promising technologies. As a result of the suggested patent analysis, four technologies out of twenty two in details classification were selected, which showed outstanding technology competitiveness, high patent share and increasing rates as well as high recent-patent-ratios and triad-patent-family-ratios. Each of the selected technologies scored more than 10 points in total, and the following four technologies were suggested as promising ones in the field of next generation mobile communication: 1) 3GPP based mobile communication, 2) beyond 4G mobile communication, 3) IEEE 802.16 based mobile communication, which are in medium classification of broadband mobile communication system, and 4) testing/certification system of mobile communication, which is in medium classification of mobile communication testing/certification system.展开更多
With recent increases in petroleum prices,there is renewed interest in vegetable oil and their derivatives as alternative fuels for diesel engines.There are more than 350 oil-bearing crops identified,
提出了一种基于Promis·e设计环境的变电站电工二次专业协同设计方法,对协同平台的建立、制图标准化、设备模型库构建以及协同设计流程等协同设计中的一些关键环节进行了描述,并结合工程实践,给出了协同设计各关键点的应用实例及解...提出了一种基于Promis·e设计环境的变电站电工二次专业协同设计方法,对协同平台的建立、制图标准化、设备模型库构建以及协同设计流程等协同设计中的一些关键环节进行了描述,并结合工程实践,给出了协同设计各关键点的应用实例及解决方案。所提出的变电站二次接线协同设计方法,已经在10余座220 k V的变电站项目中得到了应用,它可以大幅度地提高设计效率,保证设计成果的质量,具有继承性、拓展性和参照性。展开更多
文摘Optimal activation of T cells requires at least 2signals. Signal one is generated by interactionsbetween T cell receptor and antigenic peptide-majorhistocompatibility complex on antigen-presentingcells. Signal two is delivered by co-stimulatory ligandson antigen-presenting cells to their receptors on
文摘Aluminum is an important basic raw material for national economic development.The alumina industry has been expanding rapidly due to the increasing demand for aluminum.Bauxite residue is a highly alkaline solid by-product generated when alumina is extracted from bauxite ore in alumina refineries[1,2].
文摘目的评估中文版患者报告结局测量信息系统(Patient Reported Outcome Measurement Information System,PROMIS)癌症特异性抑郁项目库的心理测量学属性,构建计算机自适应测试版本(PROMIS Cancer Depression CAT),并评价其效果。方法采用便利抽样法选取2020年11月—2021年7月在上海2所三级甲等医院的648例癌症患者作为研究对象。在心理测量学评估中,首先基于Rasch模型采用残差的主成分分析、条目残差相关系数、条目特征曲线检验PROMIS癌症特异性抑郁项目库的单维性、局部独立性、单调性假设;其次,通过Rasch模型中的选项特征曲线对选项进行拟合,采用Rasch模型中的Infit MNSQ、Outfit MNSQ、难度参数对每个条目进行拟合;最后,将经过校准后的项目库内容作为PROMIS Cancer Depression CAT的题库,采用Post-hoc模拟方法评价PROMIS Cancer Depression CAT的测量效率和准确性。结果PROMIS癌症特异性抑郁项目库由测试解释的经验方差为68.6%,条目之间的残差相关值都小于0.70,条目特征曲线是单调递增曲线。PROMIS癌症特异性抑郁项目库中的5个选项的峰值均未被相邻选项的特征曲线覆盖,5个选项之间阈值的间隔均大于1且小于5,条目的Infit MNSQ值为[0.54,1.49],Outfit MNSQ值为[0.55,1.49],选项和条目的拟合均在理想范围内,可作为构建PROMIS Cancer Depression CAT的项目库。Post-hoc模拟执行CAT的θ值与整个项目库的θ值相关系数为0.964,选择的平均使用条目数为6.348个。结论中文版PROMIS癌症特异性抑郁项目库满足单维性、局部独立性以及单调性假设,可以用来构建PROMIS Cancer Depression CAT。基于PROMIS癌症特异性抑郁项目库参数构建的计算机自适应测试版本能够高效、准确地测量癌症患者的抑郁水平。
文摘In order to forecast promising technologies in the field of next generation mobile communication, various patent indicators were analyzed such as citation per patent, patent family information, patent share, increase rate, and patent activity. These indicators were quantified into several indexes and then integrated into an evaluation score to provide promising technologies. As a result of the suggested patent analysis, four technologies out of twenty two in details classification were selected, which showed outstanding technology competitiveness, high patent share and increasing rates as well as high recent-patent-ratios and triad-patent-family-ratios. Each of the selected technologies scored more than 10 points in total, and the following four technologies were suggested as promising ones in the field of next generation mobile communication: 1) 3GPP based mobile communication, 2) beyond 4G mobile communication, 3) IEEE 802.16 based mobile communication, which are in medium classification of broadband mobile communication system, and 4) testing/certification system of mobile communication, which is in medium classification of mobile communication testing/certification system.
文摘With recent increases in petroleum prices,there is renewed interest in vegetable oil and their derivatives as alternative fuels for diesel engines.There are more than 350 oil-bearing crops identified,
文摘提出了一种基于Promis·e设计环境的变电站电工二次专业协同设计方法,对协同平台的建立、制图标准化、设备模型库构建以及协同设计流程等协同设计中的一些关键环节进行了描述,并结合工程实践,给出了协同设计各关键点的应用实例及解决方案。所提出的变电站二次接线协同设计方法,已经在10余座220 k V的变电站项目中得到了应用,它可以大幅度地提高设计效率,保证设计成果的质量,具有继承性、拓展性和参照性。
