Bio-nanosensors(Bio-NSs)have attracted much attention recently due to their unique properties.Among all of the bio-NSs,the intracellular proton sensor is significant for biomedicine studies and clinic diagnosis.Proton...Bio-nanosensors(Bio-NSs)have attracted much attention recently due to their unique properties.Among all of the bio-NSs,the intracellular proton sensor is significant for biomedicine studies and clinic diagnosis.Proton nanosensors(PNSs)with different pH sensitive ranges could satisfy different research requirements.Here we report a facile method to build a PNS with a neutral to basic pH sensitive range,in which the commercial pH indicator,fluoresceinamine(FA),was covalently coupled to the carboxylic-rich amphiphilic polymer(AP)coated gold nanoparticles(AuNPs).展开更多
基金Supported by grants from the National Natural Science Foundation of China(Nos.21171086 and 81160213)Inner Mongolia Grassland Talent(No.108-108038)+1 种基金Inner Mongolia Autonomous Region Natural Science Foundation(No.2013MS1121)the Inner Mongolia Agricultural University(Nos.211-109003 and 211-206038)
文摘Bio-nanosensors(Bio-NSs)have attracted much attention recently due to their unique properties.Among all of the bio-NSs,the intracellular proton sensor is significant for biomedicine studies and clinic diagnosis.Proton nanosensors(PNSs)with different pH sensitive ranges could satisfy different research requirements.Here we report a facile method to build a PNS with a neutral to basic pH sensitive range,in which the commercial pH indicator,fluoresceinamine(FA),was covalently coupled to the carboxylic-rich amphiphilic polymer(AP)coated gold nanoparticles(AuNPs).
