当前基于MapGuide乃至其他GIS的开发领域存在着大量重复性数据访问工作,根据ORM的三层数据访问结构的工作原理,提出并初步设计了一个基于MapGuide的OSM(Object/Spatial Data Mapping)开发模式,即实现对象到空间数据的永久性映射,使用该...当前基于MapGuide乃至其他GIS的开发领域存在着大量重复性数据访问工作,根据ORM的三层数据访问结构的工作原理,提出并初步设计了一个基于MapGuide的OSM(Object/Spatial Data Mapping)开发模式,即实现对象到空间数据的永久性映射,使用该模式可以提高开发效率、降低维护复杂度。展开更多
随着开源网络地图服务Open Street Map(OSM)数据精度的提高和数据覆盖范围的扩大,其应用已逐渐渗透到各个领域,国内外专家学者对OSM的研究也不断地深入。为探究OSM在极地科考领域的应用实现,同时促进我国极地信息化事业的快速发展,从应...随着开源网络地图服务Open Street Map(OSM)数据精度的提高和数据覆盖范围的扩大,其应用已逐渐渗透到各个领域,国内外专家学者对OSM的研究也不断地深入。为探究OSM在极地科考领域的应用实现,同时促进我国极地信息化事业的快速发展,从应用角度出发,论证了OSM在补充谷歌地图实现"雪龙在线"网络信息平台功能的可行性。实现了本地OSM全球地图数据库的建设,并在实现极地网络地图服务(WMS)功能基础之上提出多源空间数据的融合与可视化表达的技术路线,为极地海冰检测与动态变化研究提供了有利的支持,为极地主管部门决策的制定与实施提供了可靠的保障。展开更多
Background Neonatal mouse heart can completely regenerate after amputating 15%of ventricular apex.However,the regenerative ability is lost by 7 day-post-birth.Cardiomyocyte dedifferentiation is the only way of existin...Background Neonatal mouse heart can completely regenerate after amputating 15%of ventricular apex.However,the regenerative ability is lost by 7 day-post-birth.Cardiomyocyte dedifferentiation is the only way of existing myocytes returning to cell cycle and initiating proliferation.Oncostatin M(OSM)was demonstrated to promote cardiomyocyte dedifferentiation after cardiac injury,while its role in heart regeneration has not been addressed.Modulating the progress of dedifferentiationproliferation through OSM may provide a clinical therapy for preventing further deterioration of patients with heart injury and restoring the lost myocardium.展开更多
目的探讨白血病抑制因子受体(leukemia inhibitory factor receptor,LIFR)在非ST段抬高型心肌梗死(non-ST-segment elevation myocardial infarction,NSTEMI)患者中的表达情况及其与心肌重构的可能关联。方法前瞻性选取2023年1月至2024...目的探讨白血病抑制因子受体(leukemia inhibitory factor receptor,LIFR)在非ST段抬高型心肌梗死(non-ST-segment elevation myocardial infarction,NSTEMI)患者中的表达情况及其与心肌重构的可能关联。方法前瞻性选取2023年1月至2024年11月于武汉大学人民医院行冠状动脉造影的急性心肌梗死患者188例,根据是否诊断为NSTEMI分为对照组94例和NSTEMI组94例。收集患者一般临床资料,采用线性回归分析LIFR及与其他指标的相关性。结果与对照组比较,NSTEMI组吸烟史、LIFR、N末端B型钠尿肽前体、肌钙蛋白I、肌酐、尿酸、白细胞计数显著升高,左心室射血分数显著降低,差异有统计学意义[48.94%vs 13.83%,P<0.01;5.82(4.23,8.11)mmol/L vs 0.97(0.60,1.41)mmol/L,P<0.01;2.53(1.24,9.71)pg/L vs 0.03(0.02,0.04),P<0.01;18.57(4.11,250.00)ng/L vs 0.00(0.00,0.00)ng/L,P<0.01;82.50(68.00,121.25)μmol/L vs 68.50(53.00,88.25)μmol/L,P<0.01;411.00(349.00,521.25)μmol/L vs 337.00(286.75,406.00)μmol/L,P<0.01;10.21(8.71,13.09)×10~9/L vs 6.22(4.67,7.46)×10~9/L,P<0.01;47.00(38.00,54.00)%vs 59.00(56.00,60.00)%,P<0.01]。心肌梗死患者血清LIFR与N末端B型钠尿肽前体、肌钙蛋白I及白细胞计数呈正相关(β=1.403,95%CI:10597.867~17327.087,P=0.000;β=0.232,95%CI:114.558~1769.808,P=0.026;β=0.336,95%CI:0.164~0.617,P=0.001)。结论LIFR可能通过炎症参与心肌梗死后心肌重构和心力衰竭的发展。展开更多
A series of materials Ce0.3+xZr0.6-xY0.1O1.95 were prepared by co-precipitation routine and the property of these materials was studied by means of oxygen storage capacity, temperature programming reduction, X-ray dif...A series of materials Ce0.3+xZr0.6-xY0.1O1.95 were prepared by co-precipitation routine and the property of these materials was studied by means of oxygen storage capacity, temperature programming reduction, X-ray diffraction, transmission electronic microscope, and X-ray photoelectron spectroscopy. The results indicate that the materials with a low Ce/Zr molar ratio possess higher cerium atom utilization ratio, reducibility and thermal stability than the materials with a high Ce/Zr ratio, and Ce0.35Zr0.55Y0.1O1.95 possesses the best properties.展开更多
The oxygen storage material (OSM) Ce0.35Zr0.55Y0.1O1.95 was prepared by co-precipitation routine and studied by means of TEM, XRD, XPS, BET, H2-TPR and oxygen storage capacity (OSC) measurements. The results indicated...The oxygen storage material (OSM) Ce0.35Zr0.55Y0.1O1.95 was prepared by co-precipitation routine and studied by means of TEM, XRD, XPS, BET, H2-TPR and oxygen storage capacity (OSC) measurements. The results indicated that this material possessed plenty of Ce3+ and lattice oxygen vacancy (percentage of Ce3+ was 59.6%) and high cerium atom utilization ratio (80.04%). The porous material was with an average BET surface area of 97 m2·g-1 and pore volume of 0.26 mL·g-1. After aged at 1 000 ℃ in air for 5 h, the sample still possessed plenty of Ce3+ and lattice oxygen vacancy (percentage of Ce3+ was 57.1%), and showed high cerium atom utilization ratio (78.25%), and high thermal stability.展开更多
文摘当前基于MapGuide乃至其他GIS的开发领域存在着大量重复性数据访问工作,根据ORM的三层数据访问结构的工作原理,提出并初步设计了一个基于MapGuide的OSM(Object/Spatial Data Mapping)开发模式,即实现对象到空间数据的永久性映射,使用该模式可以提高开发效率、降低维护复杂度。
文摘随着开源网络地图服务Open Street Map(OSM)数据精度的提高和数据覆盖范围的扩大,其应用已逐渐渗透到各个领域,国内外专家学者对OSM的研究也不断地深入。为探究OSM在极地科考领域的应用实现,同时促进我国极地信息化事业的快速发展,从应用角度出发,论证了OSM在补充谷歌地图实现"雪龙在线"网络信息平台功能的可行性。实现了本地OSM全球地图数据库的建设,并在实现极地网络地图服务(WMS)功能基础之上提出多源空间数据的融合与可视化表达的技术路线,为极地海冰检测与动态变化研究提供了有利的支持,为极地主管部门决策的制定与实施提供了可靠的保障。
文摘Background Neonatal mouse heart can completely regenerate after amputating 15%of ventricular apex.However,the regenerative ability is lost by 7 day-post-birth.Cardiomyocyte dedifferentiation is the only way of existing myocytes returning to cell cycle and initiating proliferation.Oncostatin M(OSM)was demonstrated to promote cardiomyocyte dedifferentiation after cardiac injury,while its role in heart regeneration has not been addressed.Modulating the progress of dedifferentiationproliferation through OSM may provide a clinical therapy for preventing further deterioration of patients with heart injury and restoring the lost myocardium.
文摘目的探讨白血病抑制因子受体(leukemia inhibitory factor receptor,LIFR)在非ST段抬高型心肌梗死(non-ST-segment elevation myocardial infarction,NSTEMI)患者中的表达情况及其与心肌重构的可能关联。方法前瞻性选取2023年1月至2024年11月于武汉大学人民医院行冠状动脉造影的急性心肌梗死患者188例,根据是否诊断为NSTEMI分为对照组94例和NSTEMI组94例。收集患者一般临床资料,采用线性回归分析LIFR及与其他指标的相关性。结果与对照组比较,NSTEMI组吸烟史、LIFR、N末端B型钠尿肽前体、肌钙蛋白I、肌酐、尿酸、白细胞计数显著升高,左心室射血分数显著降低,差异有统计学意义[48.94%vs 13.83%,P<0.01;5.82(4.23,8.11)mmol/L vs 0.97(0.60,1.41)mmol/L,P<0.01;2.53(1.24,9.71)pg/L vs 0.03(0.02,0.04),P<0.01;18.57(4.11,250.00)ng/L vs 0.00(0.00,0.00)ng/L,P<0.01;82.50(68.00,121.25)μmol/L vs 68.50(53.00,88.25)μmol/L,P<0.01;411.00(349.00,521.25)μmol/L vs 337.00(286.75,406.00)μmol/L,P<0.01;10.21(8.71,13.09)×10~9/L vs 6.22(4.67,7.46)×10~9/L,P<0.01;47.00(38.00,54.00)%vs 59.00(56.00,60.00)%,P<0.01]。心肌梗死患者血清LIFR与N末端B型钠尿肽前体、肌钙蛋白I及白细胞计数呈正相关(β=1.403,95%CI:10597.867~17327.087,P=0.000;β=0.232,95%CI:114.558~1769.808,P=0.026;β=0.336,95%CI:0.164~0.617,P=0.001)。结论LIFR可能通过炎症参与心肌梗死后心肌重构和心力衰竭的发展。
文摘A series of materials Ce0.3+xZr0.6-xY0.1O1.95 were prepared by co-precipitation routine and the property of these materials was studied by means of oxygen storage capacity, temperature programming reduction, X-ray diffraction, transmission electronic microscope, and X-ray photoelectron spectroscopy. The results indicate that the materials with a low Ce/Zr molar ratio possess higher cerium atom utilization ratio, reducibility and thermal stability than the materials with a high Ce/Zr ratio, and Ce0.35Zr0.55Y0.1O1.95 possesses the best properties.
文摘The oxygen storage material (OSM) Ce0.35Zr0.55Y0.1O1.95 was prepared by co-precipitation routine and studied by means of TEM, XRD, XPS, BET, H2-TPR and oxygen storage capacity (OSC) measurements. The results indicated that this material possessed plenty of Ce3+ and lattice oxygen vacancy (percentage of Ce3+ was 59.6%) and high cerium atom utilization ratio (80.04%). The porous material was with an average BET surface area of 97 m2·g-1 and pore volume of 0.26 mL·g-1. After aged at 1 000 ℃ in air for 5 h, the sample still possessed plenty of Ce3+ and lattice oxygen vacancy (percentage of Ce3+ was 57.1%), and showed high cerium atom utilization ratio (78.25%), and high thermal stability.
