A compound ethyl(5S,6R)-2-(4-methylphenyl)-6-[(1R)-tert-butyldimethylsilyloxyethy]-penem-3-carboxylate was synthesized through displacement,acylation and Wittig cyclization reaction of optically active material(3R,4R)...A compound ethyl(5S,6R)-2-(4-methylphenyl)-6-[(1R)-tert-butyldimethylsilyloxyethy]-penem-3-carboxylate was synthesized through displacement,acylation and Wittig cyclization reaction of optically active material(3R,4R)-3-[(1R)-tert-butyldimethylsilyloxyethyl]-4-acetoxy-2-azetidi-none(4AA)upon thionocarboxlic acid.The intermediates and the target product were characterized by 1HNMR,IR,elementary analysis and MS.展开更多
A new method has been developed for separation and determination of zinc,copper,cobalt and nickel based on their colour chelates with 6,6″-dimethyl-4′-phenyl-2,2′:6′,2″-terpyridine（TPY） by ion pair high perform...A new method has been developed for separation and determination of zinc,copper,cobalt and nickel based on their colour chelates with 6,6″-dimethyl-4′-phenyl-2,2′:6′,2″-terpyridine（TPY） by ion pair high performance liquid chromatography in a reversed phase mode.The suitable conditions are the methanol-water（80:20,V/V） containing 10mmol/L NaH2PO4-H3PO4 buffer solution（pH=5.0） and 3.0mmol/L sodium dodecyl sulfonate as mobile phase,on a Symmetry C18 column（3.9mmID×150mm）,the flow rate of the mobile phase is 1.0mL/min.Spectrophotometric detection was made at 340nm.The detective limits are 0.05,0.10,2.00 and 0.50ng/mL respectively.The method has good selectivity and sensitivity.It has been applied to the separation and determination of zinc,copper,cobalt and nickel in human hair and tobacco and the result is satisfied.展开更多
文摘A compound ethyl(5S,6R)-2-(4-methylphenyl)-6-[(1R)-tert-butyldimethylsilyloxyethy]-penem-3-carboxylate was synthesized through displacement,acylation and Wittig cyclization reaction of optically active material(3R,4R)-3-[(1R)-tert-butyldimethylsilyloxyethyl]-4-acetoxy-2-azetidi-none(4AA)upon thionocarboxlic acid.The intermediates and the target product were characterized by 1HNMR,IR,elementary analysis and MS.
文摘A new method has been developed for separation and determination of zinc,copper,cobalt and nickel based on their colour chelates with 6,6″-dimethyl-4′-phenyl-2,2′:6′,2″-terpyridine（TPY） by ion pair high performance liquid chromatography in a reversed phase mode.The suitable conditions are the methanol-water（80:20,V/V） containing 10mmol/L NaH2PO4-H3PO4 buffer solution（pH=5.0） and 3.0mmol/L sodium dodecyl sulfonate as mobile phase,on a Symmetry C18 column（3.9mmID×150mm）,the flow rate of the mobile phase is 1.0mL/min.Spectrophotometric detection was made at 340nm.The detective limits are 0.05,0.10,2.00 and 0.50ng/mL respectively.The method has good selectivity and sensitivity.It has been applied to the separation and determination of zinc,copper,cobalt and nickel in human hair and tobacco and the result is satisfied.
