以间苯二胺为原料,与酰化剂甲酸反应制得中间体N,N'-二甲酰基间苯二胺,再以NABH4-I2为还原剂合成得到产品N,N'-二甲基间苯二胺,对合成工艺进行了优化,并分析了还原机理,化合物的结构经IR,1 H NMR和MS分析确定.该法原料易得,反...以间苯二胺为原料,与酰化剂甲酸反应制得中间体N,N'-二甲酰基间苯二胺,再以NABH4-I2为还原剂合成得到产品N,N'-二甲基间苯二胺,对合成工艺进行了优化,并分析了还原机理,化合物的结构经IR,1 H NMR和MS分析确定.该法原料易得,反应条件要求低,收率高且成本更低.展开更多
3,5-dimethyl phenyl isocyanate was prepared by the method of trichloromethyl chloroformate in 70% yield.New compound N,N′-di-(3,5-dimethyl)phenyl-3,6-dimethyl-1,4-dihydro-1,2,4,5-tetrazine-1,4-dicarboamide was synthe...3,5-dimethyl phenyl isocyanate was prepared by the method of trichloromethyl chloroformate in 70% yield.New compound N,N′-di-(3,5-dimethyl)phenyl-3,6-dimethyl-1,4-dihydro-1,2,4,5-tetrazine-1,4-dicarboamide was synthesized by reacting 3,5-dimethyl phenyl isocyanate and 3,6-dimethyl-1,6-dihydro-1,2,4,5-tetrazine.Its post-disposal method had been improved.yield being 30.8%.Byproduct 1,3-bis-(3,5-dimethyphenyl)-1,3-diazetidine-2,4-dione have not been reported,too.Their structures were conformed by IR, 1HNMR and elemental analysis.展开更多
文摘3,5-dimethyl phenyl isocyanate was prepared by the method of trichloromethyl chloroformate in 70% yield.New compound N,N′-di-(3,5-dimethyl)phenyl-3,6-dimethyl-1,4-dihydro-1,2,4,5-tetrazine-1,4-dicarboamide was synthesized by reacting 3,5-dimethyl phenyl isocyanate and 3,6-dimethyl-1,6-dihydro-1,2,4,5-tetrazine.Its post-disposal method had been improved.yield being 30.8%.Byproduct 1,3-bis-(3,5-dimethyphenyl)-1,3-diazetidine-2,4-dione have not been reported,too.Their structures were conformed by IR, 1HNMR and elemental analysis.
