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Shear strength characteristics of mixing slag-stone ballast reinforcement with tire geo-scrap using large-scale direct shear tests
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作者 Morteza Esmaeili Hamidreza Heydari +1 位作者 Maziar Mokhtari Sara Darvishi 《Railway Engineering Science》 2025年第1期94-107,共14页
Utilizing the ballast layer with more durable and stable characteristics can help avoid significant expenses due to decreased maintenance efforts.Strengthening the ballast layer with different types of reinforcements ... Utilizing the ballast layer with more durable and stable characteristics can help avoid significant expenses due to decreased maintenance efforts.Strengthening the ballast layer with different types of reinforcements or substituting the stone aggregates with the appropriate granular materials could potentially help to achieve this goal by reducing the ballast deterioration.One of the exquisite and most effective solutions to eliminate these challenges is to use waste materials such as steel slag aggregates and useless tires.Utilizing these waste materials in the ballasted railway track will contribute to sustainable development,an eco-friendly system,and green infrastructure.So in a state-of-the-art insightful,the ballast aggregates,including a mixture of steel slag and stone aggregates,are reinforced with a novel kind of geo-grid made of waste tire strips known as geo-scraps.This laboratory research tried to explain the shear strength behavior of the introduced mixing slag-stone ballast reinforced with tire geo-scrap.To achieve this goal,a series of large-scale direct shear tests were performed on the ballast which is reinforced by tire geo-scrap and included various combinations of slag and stone aggregates.The concluded results indicate that the optimal mixing ratio is attained by a combination of 75%slag and 25%stone aggregates which is reinforced by tire geo-scrap at a placing level of 120 mm.In this case,the shear strength,internal friction angle,vertical displacement,and dilatancy angle of stone–slag ballast reinforced with geo-scraps exhibited average changes of+28%,+9%,-28%,and-15%,respectively. 展开更多
关键词 Ballast deterioration Ballast stabilization Steel slag aggregates Large-scale direct shear test Waste tire geoscrap
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LDRA Testbed在动车EBCU软件测试中的应用与研究
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作者 王贤斌 《现代信息科技》 2025年第1期155-160,共6页
动车制动控制系统是高铁安全运行的重要保障。随着动车系统的复杂性和自动化程度的提高,对制动控制系统的软件测试也提出了更高的要求。文章通过将LDRA Testbed软件自动化测试工具应用于动车EBCU软件,详细介绍了静态分析、单元测试及集... 动车制动控制系统是高铁安全运行的重要保障。随着动车系统的复杂性和自动化程度的提高,对制动控制系统的软件测试也提出了更高的要求。文章通过将LDRA Testbed软件自动化测试工具应用于动车EBCU软件,详细介绍了静态分析、单元测试及集成测试的方法和步骤,并结合实际测试结果分析其有效性和重要性。通过全面的测试手段,不仅提高了EBCU软件的可靠性和安全性,还为动车制动控制系统的维护和优化提供了科学依据。 展开更多
关键词 动车 制动控制系统 testBED 静态分析 单元测试 集成测试
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pytest自动测试框架通用搭建方法研究
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作者 邢浩 孙孟宇 石杰 《山西电子技术》 2025年第1期102-105,共4页
Pytest是一种基于python的自动测试框架,可以实现测试代码的自动化执行,应用十分广泛。由于Pytest支持测试代码自动执行、并行执行、测试报告自动生成等多种功能,因此在搭建pytest开发环境时需要安装各种第三方插件和python依赖包,这给p... Pytest是一种基于python的自动测试框架,可以实现测试代码的自动化执行,应用十分广泛。由于Pytest支持测试代码自动执行、并行执行、测试报告自动生成等多种功能,因此在搭建pytest开发环境时需要安装各种第三方插件和python依赖包,这给pytest开发环境的搭建带来了麻烦。为了给pytest使用人员提供便利,对pytest自动测试框架的通用搭建方法进行了研究。首先介绍了pytest自动测试框架的应用领域和特点;然后分别对联网环境和离网环境下pytest的搭建方法进行了介绍;之后分析了不同操作系统下pytest安装方法的通用性;最后对pytest通用安装方法的应用效果进行了说明。 展开更多
关键词 pytest 自动测试框架 通用搭建方法 联网搭建 离网搭建
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Investigation on the test method of rupture forces of thermal bonding seams in nonwovens shopping bags
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作者 王来力 吴雄英 丁雪梅 《产业用纺织品》 北大核心 2009年第11期41-44,共4页
超声波热黏合的非织造布接缝不同于普通机织物和针织物等的车缝接缝。运用正交试验设计方法,对纺粘法PP非织造布购物袋热黏合接缝断裂强力测试中的试样宽度、拉伸速率和隔距三个因素进行优化。试验结果表明,试样宽度对纺粘法PP非织造... 超声波热黏合的非织造布接缝不同于普通机织物和针织物等的车缝接缝。运用正交试验设计方法,对纺粘法PP非织造布购物袋热黏合接缝断裂强力测试中的试样宽度、拉伸速率和隔距三个因素进行优化。试验结果表明,试样宽度对纺粘法PP非织造布热黏合接缝断裂强力的测试结果影响最大,并且接缝的断裂强力随着试样宽度的增加而增加。选用试样宽度为200mm、拉伸速率为50mm/min、隔距为100mm的组合所得出的测试结果能比较真实地反映实际的接缝断裂强力。 展开更多
关键词 非织造布 热黏合接缝 测试方法 正交试验
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Thermal-Hydraulic System Study of the Helium Cooled Pebble Bed (HCPB) Test Blanket Module (TBM) for ITER Using System Code RELAP5 被引量:2
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作者 金雪舟 R.Meyder 《Plasma Science and Technology》 SCIE EI CAS CSCD 2005年第2期2753-2757,共5页
The HCPB concept has been a European DEMO reference concept for nearly one decade. Detailed thermal-hydraulic study on the control behavior of the whole system is one of the important parts of this development. The th... The HCPB concept has been a European DEMO reference concept for nearly one decade. Detailed thermal-hydraulic study on the control behavior of the whole system is one of the important parts of this development. The thermal-hydraulic effect of the TBM-combined cooling circuit during a cyclic operation in ITER has been studied using the system code RELAP5. The RELAP5 is based on an one-dimensional, transient two-fluid model for the flow of a two-phase steam-water mixture that can contain noncondensable components like Helium. The RELAP5models are modified to take the cyclic operation of the circulator, heat, exchanger, bypass, valves etc in to account. A sequence of operational phases is investigated, starting from the cold state through the heating phase that brings the system to a stand-by condition, followed by typical power cycles applied in ITER. The results show that the implemented control mechanisms keep the inlet temperature to the TBM and the total mass flow rate at the required values through all phases. 展开更多
关键词 test blanket module helium cooled pebble bed RELAP5 cooling system
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Nondestructive testing method of wood moisture content based on a planar capacitance sensor model 被引量:3
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作者 WANG Jue LUO Yue-sheng LIU Shao-gang 《Forestry Studies in China》 CAS 2010年第3期142-146,共5页
For our research, a new hybrid experimental-computational method is presented. We applied a least squares fitting method (LSFM) to reconstruct the wood moisture content (WMC) from the data measured with a planar c... For our research, a new hybrid experimental-computational method is presented. We applied a least squares fitting method (LSFM) to reconstruct the wood moisture content (WMC) from the data measured with a planar capacitance sensor. A boundary element method (BEM) was used to compute the relationship between capacitance and the dielectric constant. A functional relationship between MC and the dielectric constant was identified by LSFM. The agreement of this final computation result with the experimental data indicates that this method can be used to estimate the WMC quickly and effectively with engineering analysis. Compared with popular statistical methods, a large number of experiments are avoided, some costs of testing are reduced and the efficiency of testing is enhanced. 展开更多
关键词 planar capacitance sensor nondestructive testing wood moisture content boundary element method least squares fitring method
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昆明烟区土壤线虫数量与环境因子的Mantel Test分析
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作者 施锘 李恩星 +9 位作者 陈江政 蒋碧霞 吴思昊 贺艳杰 王戈 王娜 白羽祥 周鹏 杜宇 李杰 《山东农业科学》 北大核心 2024年第10期153-158,共6页
为进一步明确昆明烟区影响线虫的环境因素,于2022年采集云南昆明烟区8个县(市、区)64个乡镇的320个植烟土壤样品,调查与测定样品采集地的海拔、土壤线虫数量以及土壤理化性质(pH值及有机质、水解性氮、速效钾和有效磷含量),并探讨土壤... 为进一步明确昆明烟区影响线虫的环境因素,于2022年采集云南昆明烟区8个县(市、区)64个乡镇的320个植烟土壤样品,调查与测定样品采集地的海拔、土壤线虫数量以及土壤理化性质(pH值及有机质、水解性氮、速效钾和有效磷含量),并探讨土壤线虫数量与植烟土壤环境因子之间的潜在关系。结果表明,昆明烟区土壤线虫数量一定程度上受到海拔及土壤理化性质的影响,海拔与有机质、水解性氮和速效钾呈显著正相关,pH值与有效磷呈极显著负相关,相关系数为-0.850;土壤线虫数量与土壤有效磷呈正相关,与海拔、pH值、有机质、水解性氮、速效钾呈负相关,其中与海拔、有机质和水解性氮的相关系数较大,分别为-0.751、-0.651和-0.568。通过Mantel test分析确定海拔、有机质和水解性氮含量是影响昆明烟区土壤线虫数量的重要因子。本结果可为有效防治土壤线虫提供科学依据。 展开更多
关键词 土壤线虫 海拔 土壤理化特性 Mantel test分析
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Unbound^(28)O,the heaviest oxygen isotope observed:a cutting-edge probe for testing nuclear models 被引量:1
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作者 Jian-Guo Li Bai-Shan Hu +1 位作者 Shuang Zhang Fu-Rong Xu 《Nuclear Science and Techniques》 SCIE EI CAS CSCD 2024年第2期1-2,共2页
The beyond-dripline oxygen isotopes^(27,28)O were recently observed at RIKEN,and were found to be unbound decaying into^(24)O by emitting neutrons.The unbound feature of the heaviest oxygen isotope,^(28)O,provides an ... The beyond-dripline oxygen isotopes^(27,28)O were recently observed at RIKEN,and were found to be unbound decaying into^(24)O by emitting neutrons.The unbound feature of the heaviest oxygen isotope,^(28)O,provides an excellent test for stateof-the-art nuclear models.The atomic nucleus is a self-organized quantum manybody system comprising specific numbers of protons Z and neutrons N. 展开更多
关键词 testING QUANTUM system
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A test method for evaluating the thermal environment of underground coal mine refuge alternatives
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作者 D.S.Yantek L.Yan +2 位作者 N.W.Damiano M.A.Reyes J.R.Srednicki 《International Journal of Mining Science and Technology》 SCIE EI CSCD 2019年第3期343-355,共13页
Since 2009,the Mine Safety and Health Administration(MSHA)has required mines to install refuge alternatives(RAs)in underground coal mines.One of the biggest concerns with occupied RAs is the possible severity of the r... Since 2009,the Mine Safety and Health Administration(MSHA)has required mines to install refuge alternatives(RAs)in underground coal mines.One of the biggest concerns with occupied RAs is the possible severity of the resulting thermal environment.In 30 CFR 7.504,the maximum allowable apparent temperature(AT)for an occupied RA is specified as 35℃(95°F).Manufacturers must conduct heat/humidity tests to demonstrate that their RAs meet the 35℃(95°F)AT limit.For these tests,heat input devices are used to input the metabolic heat of actual miners.A wide variety of test methods,sensors,and heat input devices could be used when conducting such tests.Since 2012,the National Institute for Occupational Safety and Health(NIOSH)has conducted over thirty 96-hour heat/humidity tests on four different RAs.This paper discusses the test equipment and procedures used during these investigations.This information is useful for RA manufacturers conducting RA heat/humidity tests,for other researchers investigating RA heat/humidity buildup,and for those who need to assess the thermal environment of any confined space where people may be trapped or are seeking refuge. 展开更多
关键词 REFUGE CHAMBER REFUGE ALTERNATIVE CONFINED space thermal environment test method Temperature
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Thermal analysis and tests of W/Cu brazing for primary collimator scraper in CSNS/RCS
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作者 Jie-Bing Yu Jia-Xin Chen +2 位作者 Ling Kang Jie-Feng Wu Yi-Qing Zou 《Nuclear Science and Techniques》 SCIE CAS CSCD 2017年第4期19-23,共5页
To the transverse beam collimation system in a rapid cycling synchrotron,an important component is the primary collimator,which improves emittance of the beam halo particles such that the particles outside the predefi... To the transverse beam collimation system in a rapid cycling synchrotron,an important component is the primary collimator,which improves emittance of the beam halo particles such that the particles outside the predefined trajectory can be absorbed by the secondary collimators.Given the material properties and power deposition distribution,the beam scraper of the primary collimator is a0.17 mm tungsten foil on a double face-wedged copper block of 121.5 mm x 20 mm.The heat is transferred to the outside by a φ34 mm copper rod.In this paper,for minimizing brazing thermal stress,we report our theoretical analysis and tests on brazing the tungsten and copper materials which differ greatly in size.We show that the thermal stress effect can be controlled effectively by creating stress relief grooves on the copper block and inserting a tungsten transition layer into the copper block.This innovation contributes to the successful R&D of the primary collimator.And this study may be of help for working out a brazing plan of similar structures. 展开更多
关键词 SCRAPER of PRIMARY COLLIMATOR of CSNS/RCS W/Cu BRAZING thermal analysis BRAZING tests
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Micromechanical testing and property upscaling of planetary rocks:A critical review 被引量:2
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作者 Yiwei Liu Guoping Zhang +1 位作者 Jiangmei Qiao Xuhai Tang 《International Journal of Mining Science and Technology》 SCIE EI CAS CSCD 2024年第9期1217-1241,共25页
Knowledge of the mechanical behavior of planetary rocks is indispensable for space explorations.The scarcity of pristine samples and the irregular shapes of planetary meteorites make it difficult to obtain representat... Knowledge of the mechanical behavior of planetary rocks is indispensable for space explorations.The scarcity of pristine samples and the irregular shapes of planetary meteorites make it difficult to obtain representative samples for conventional macroscale rock mechanics experiments(macro-RMEs).This critical review discusses recent advances in microscale RMEs(micro-RMEs)techniques and the upscaling methods for extracting mechanical parameters.Methods of mineralogical and microstructural analyses,along with non-destructive mechanical techniques,have provided new opportunities for studying planetary rocks with unprecedented precision and capabilities.First,we summarize several mainstream methods for obtaining the mineralogy and microstructure of planetary rocks.Then,nondestructive micromechanical testing methods,nanoindentation and atomic force microscopy(AFM),are detailed reviewed,illustrating the principles,advantages,influencing factors,and available testing results from literature.Subsequently,several feasible upscaling methods that bridge the micro-measurements of meteorite pieces to the strength of the intact body are introduced.Finally,the potential applications of planetary rock mechanics research to guiding the design and execution of space missions are environed,ranging from sample return missions and planetary defense to extraterrestrial construction.These discussions are expected to broaden the understanding of the microscale mechanical properties of planetary rocks and their significant role in deep space exploration. 展开更多
关键词 METEORITES Planetary rock mechanics Non-destructive testing Upscaling method Extraterrestrial construction Space exploration
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Aquifer Test求群孔抽水试验水文地质参数
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作者 李红伟 《中国高新科技》 2024年第5期56-57,129,共3页
在水文地质条件复杂的地区,往往采用大型的群孔抽水试验充分揭露含水层特征,获取水文地质参数。用Aquifer Test软件求解水文地质参数,则方便实用、简捷高效,可快速输出拟合图形和求参结果。Aquifer Test提供了丰富的求参方案,求参必须... 在水文地质条件复杂的地区,往往采用大型的群孔抽水试验充分揭露含水层特征,获取水文地质参数。用Aquifer Test软件求解水文地质参数,则方便实用、简捷高效,可快速输出拟合图形和求参结果。Aquifer Test提供了丰富的求参方案,求参必须结合当地当时的水文地质条件实际情况考虑,选择适合的方案和时空数据求取水文地质参数。 展开更多
关键词 群孔抽水试验 水文地质参数 Aquifer test
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Pilot Test Conducted for Thermal Recoveryof Viscous Crude in Baisc Basin
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《China Oil & Gas》 CAS 1997年第1期38-38,共1页
关键词 test Pilot test Conducted for thermal Recoveryof Viscous Crude in Baisc Basin
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Development of multi-functional anchorage support dynamic-static coupling performance test system and its application
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作者 Qi Wang Shuo Xu +4 位作者 Bei Jiang Chong Zhang Zhe Sun Jingxuan Liu Cailin Jiao 《International Journal of Mining Science and Technology》 SCIE EI CAS CSCD 2024年第3期339-349,共11页
In underground engineering with complex conditions,the bolt(cable)anchorage support system is in an environment where static and dynamic stresses coexist,under the action of geological conditions such as high stresses... In underground engineering with complex conditions,the bolt(cable)anchorage support system is in an environment where static and dynamic stresses coexist,under the action of geological conditions such as high stresses and strong disturbances and construction conditions such as the application of high prestress.It is essential to study the support components performance under dynamic-static coupling conditions.Based on this,a multi-functional anchorage support dynamic-static coupling performance test system(MAC system)is developed,which can achieve 7 types of testing functions,including single component performance,anchored net performance,anchored rock performance and so on.The bolt and cable mechanical tests are conducted by MAC system under different prestress levels.The results showed that compared to the non-prestress condition,the impact resistance performance of prestressed bolts(cables)is significantly reduced.In the prestress range of 50–160 k N,the maximum reduction rate of impact energy resisted by different types of bolts is 53.9%–61.5%compared to non-prestress condition.In the prestress range of 150–300 k N,the impact energy resisted by high-strength cable is reduced by76.8%–84.6%compared to non-prestress condition.The MAC system achieves dynamic-static coupling performance test,which provide an effective means for the design of anchorage support system. 展开更多
关键词 Anchorage support system Development of test system Dynamic-static coupling test Combined stress
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Research on aiming methods for small sample size shooting tests of two-dimensional trajectory correction fuse
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作者 Chen Liang Qiang Shen +4 位作者 Zilong Deng Hongyun Li Wenyang Pu Lingyun Tian Ziyang Lin 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2024年第3期506-517,共12页
The longitudinal dispersion of the projectile in shooting tests of two-dimensional trajectory corrections fused with fixed canards is extremely large that it sometimes exceeds the correction ability of the correction ... The longitudinal dispersion of the projectile in shooting tests of two-dimensional trajectory corrections fused with fixed canards is extremely large that it sometimes exceeds the correction ability of the correction fuse actuator.The impact point easily deviates from the target,and thus the correction result cannot be readily evaluated.However,the cost of shooting tests is considerably high to conduct many tests for data collection.To address this issue,this study proposes an aiming method for shooting tests based on small sample size.The proposed method uses the Bootstrap method to expand the test data;repeatedly iterates and corrects the position of the simulated theoretical impact points through an improved compatibility test method;and dynamically adjusts the weight of the prior distribution of simulation results based on Kullback-Leibler divergence,which to some extent avoids the real data being"submerged"by the simulation data and achieves the fusion Bayesian estimation of the dispersion center.The experimental results show that when the simulation accuracy is sufficiently high,the proposed method yields a smaller mean-square deviation in estimating the dispersion center and higher shooting accuracy than those of the three comparison methods,which is more conducive to reflecting the effect of the control algorithm and facilitating test personnel to iterate their proposed structures and algorithms.;in addition,this study provides a knowledge base for further comprehensive studies in the future. 展开更多
关键词 Two-dimensional trajectory correction fuse Small sample size test Compatibility test KL divergence Fusion bayesian estimation
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Evaluation Test Research of DR Inspection System for Circumferential Welds in Long Distance Pipeline
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作者 WANG Changjiang WANG Xue +4 位作者 ZHANG Shimin ZHAO Yan LYU Xinyu ZHONG Qian ZHOU Guangyan 《材料导报》 EI CAS CSCD 北大核心 2024年第22期223-229,共7页
Digital radiographic(DR)testing equipment has been widely promoted and applied in the inspection of circumferential welds in oil and gas pipelines.In order to establish a comprehensive quality control system for digit... Digital radiographic(DR)testing equipment has been widely promoted and applied in the inspection of circumferential welds in oil and gas pipelines.In order to establish a comprehensive quality control system for digital radiographic testing and fully evaluate the integrated system inspection ability of equipment,personnel,and processes,a scientific and standardized evaluation method to the system is very necessary.Here investigates the precedents of relevant non-destructive testing evaluation methods at home and abroad,considers the testing characteristics of DR equipment,develops a complete set of DR testing system evaluation procedures.It deeply studies the adaptability methods of program processes from defect production to slicing processing and data statistical calculation for digital radiographic testing evaluation.To check the repeatability and reliability of the detectable system,five process welds with 200 real metallographic defects were fabricated in the laboratory.From the detected results,the DR system has good repeatability in image quality,and the detectable defect size reaches 0.85 mm under achieving 90%detection probability at a confidence level of 95%,the error of detected defect length is±2 mm,and the error of detected defect localization is±5 mm.The qualitative and quantitative detection of defects are accurate and reliable.The test further confirmed the reliable detection ability of the DR detection system,and fully validated the scientific and practical evaluation method designed.The research on the evaluation test method can serve as an important link in the quality control system for the on-site application of digital ray equipment in long-distance pipelines.The designed program,test,and evaluation content can serve as an important basis for the formulation of relevant specifications or standards. 展开更多
关键词 digital ray evaluation test REPEATABILITY RELIABILITY
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THE SCHUR TEST OF COMPACT OPERATORS
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作者 Qijian KANG Maofa WANG 《Acta Mathematica Scientia》 SCIE CSCD 2024年第5期2041-2050,共10页
Infinite matrix theory is an important branch of function analysis.Every linear operator on a complex separable infinite dimensional Hilbert space corresponds to an infinite matrix with respect a orthonormal base of t... Infinite matrix theory is an important branch of function analysis.Every linear operator on a complex separable infinite dimensional Hilbert space corresponds to an infinite matrix with respect a orthonormal base of the space,but not every infinite matrix corresponds to an operator.The classical Schur test provides an elegant and useful criterion for the boundedness of linear operators,which is considered a respectable mathematical accomplishment.In this paper,we prove the compact version of the Schur test.Moreover,we provide the Schur test for the Schatten class S_(2).It is worth noting that our main results can be applicable to the general matrix without limitation on non-negative numbers.We finally provide the Schur test for compact operators from l_(p) into l_(q). 展开更多
关键词 Schur test compact operator infinite matrix
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Research on Automatic Test System of Engine Blade Natural Frequency
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作者 LU Yonghua LIU Jingjing +2 位作者 YANG Haibo HUANG Chuan MA Zhicheng 《Transactions of Nanjing University of Aeronautics and Astronautics》 EI CSCD 2024年第4期476-487,共12页
Blades are one of the important components on aircraft engines.If they break due to vibration failure,the normal operation of the entire engine will be offected.Therefore,it is necessary to measure their natural frequ... Blades are one of the important components on aircraft engines.If they break due to vibration failure,the normal operation of the entire engine will be offected.Therefore,it is necessary to measure their natural frequency before installing them on the engine to avoid resonance.At present,most blade vibration testing systems require manual operation by operators,which has high requirements for operators and the testing process is also very cumbersome.Therefore,the testing efficiency is low and cannot meet the needs of efficient testing.To solve the current problems of low testing efficiency and high operational requirements,a high-precision and high-efficiency automatic test system is designed.The testing accuracy of this system can reach ±1%,and the testing efficiency is improved by 37% compared to manual testing.Firstly,the influence of compression force and vibration exciter position on natural frequency test is analyzed by amplitude-frequency curve,so as to calibrate servo cylinder and fourdimensional motion platform.Secondly,the sine wave signal is used as the excitation to sweep the blade linearly,and the natural frequency is determined by the amplitude peak in the frequency domain.Finally,the accuracy experiment and efficiency experiment are carried out on the developed test system,whose results verify its high efficiency and high precision. 展开更多
关键词 BLADE vibration failure natural frequency automatic test system
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Investigation of the cell composition and gene expression in the delayed-type hypersensitivity tuberculin skin test
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作者 Hui-Juan Duan Hong-Qian Chu +4 位作者 Ting-Ming Cao Guang-Ming Dai Na Tian Gang Sheng Zhao-Gang Sun 《Military Medical Research》 SCIE CAS CSCD 2024年第1期148-151,共4页
Dear Editor,The tuberculin skin test(TST)reagents have continuously improved,with the ESAT6-CFP10(EC)test having recently been introduced,but are seldom based on the direction of the delayed-type hypersensitivity(DTH)... Dear Editor,The tuberculin skin test(TST)reagents have continuously improved,with the ESAT6-CFP10(EC)test having recently been introduced,but are seldom based on the direction of the delayed-type hypersensitivity(DTH)mechanism.Previous studies only partially showed the infiltration and activation of immune cells and the production of cytokines of the skin induration[1,2],and lack the detailed measurements of cell proportions and gene expression in the DTH response.Therefore,in this study,we revealed the comprehensive characteristics of DTH by single-cell RNA sequencing(scRNA-seq)in the guinea pig tuberculosis(TB)model[Experimental Animal Welfare Ethics Committee,Beijing Tuberculosis and Thoracic Tumor Research Institute(2021-064)]. 展开更多
关键词 Tuberculin skin test Delayed-type hypersensitivity Single-cell RNA sequencing
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Optimality of Group Testing with Differential Misclassification
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作者 LI Yiming ZHANG Hong LIU Aiyi 《应用概率统计》 CSCD 北大核心 2024年第4期644-662,共19页
Group testing is a method that can be used to estimate the prevalence of rare infectious diseases,which can effectively save time and reduce costs compared to the method of random sampling.However,previous literature ... Group testing is a method that can be used to estimate the prevalence of rare infectious diseases,which can effectively save time and reduce costs compared to the method of random sampling.However,previous literature only demonstrated the optimality of group testing strategy while estimating prevalence under some strong assumptions.This article weakens the assumption of misclassification rate in the previous literature,considers the misclassification rate of the infected samples as a differentiable function of the pool size,and explores some optimal properties of group testing for estimating prevalence in the presence of differential misclassification conforming to this assumption.This article theoretically demonstrates that the group testing strategy performs better than the sample by sample procedure in estimating disease prevalence when the total number of sample pools is given or the size of the test population is determined.Numerical simulation experiments were conducted to evaluate the performance of group tests in estimating prevalence in the presence of dilution effect. 展开更多
关键词 group testing sensitivity SPECIFICITY dilution effect differential misclassification PREVALENCE
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