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m^(6)A modification of lncRNA in middle ear cholesteatoma
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作者 HE Jun XIE Shumin +3 位作者 JIN Li FU Jinfeng YUAN Qiulin LIU Wei 《中南大学学报(医学版)》 CAS CSCD 北大核心 2024年第5期667-678,共12页
Objective:Middle ear cholesteatoma is a non-tumorous condition that typically leads to hearing loss,bone destruction,and other severe complications.Despite surgery being the primary treatment,the recurrence rate remai... Objective:Middle ear cholesteatoma is a non-tumorous condition that typically leads to hearing loss,bone destruction,and other severe complications.Despite surgery being the primary treatment,the recurrence rate remains high.Therefore,exploring the molecular mechanisms underlying cholesteatoma is crucial for discovering new therapeutic approaches.This study aims to explore the involvement of N6-methyladenosine(m^(6)A)methylation in long non-coding RNAs(lncRNAs)in the biological functions and related pathways of middle ear cholesteatoma.Methods:The m^(6)A modification patterns of lncRNA in middle ear cholesteatoma tissues(n=5)and normal post-auricular skin tissues(n=5)were analyzed using an lncRNA m^(6)A transcriptome microarray.Gene Ontology(GO)and Kyoto Encyclopedia of Genes and Genomes(KEGG)pathway analyses were conducted to identify potential biological functions and signaling pathways involved in the pathogenesis of middle ear cholesteatoma.Methylated RNA immunoprecipitation(MeRIP)-PCR was used to validate the m^(6)A modifications in cholesteatoma and normal skin tissues.Results:Compared with normal skin tissues,1525 lncRNAs were differentially methylated in middle ear cholesteatoma tissues,with 1048 showing hypermethylation and 477 showing hypomethylation[fold change(FC)≥3 or<1/3,P<0.05].GO enrichment analysis indicated that hypermethylated lncRNAs were involved in protein phosphatase inhibitor activity,neuron-neuron synapse,and regulation ofα-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid(AMPA)receptor activity.Hypomethylated lncRNAs were associated with mRNA methyltransferase activity,secretory granule membrane,and mRNA methylation.KEGG analysis revealed that hypermethylated lncRNAs were mainly associated with 5 pathways:the Hedgehog signaling pathway,viral protein interaction with cytokines and cytokine receptors,mitogen-activated protein kinase(MAPK)signaling pathway,cytokine-cytokine receptor interaction,and adrenergic signaling in cardiomyocytes.Hypomethylated lncRNAs were mainly involved in 4 pathways:Renal cell carcinoma,tumor necrosis factor signaling pathway,transcriptional misregulation in cancer,and cytokine-cytokine receptor interaction.Additionally,MeRIP-PCR confirmed the changes in m^(6)A methylation levels in NR_033339,NR_122111,NR_130744,and NR_026800,consistent with microarray analysis.Real-time PCR also confirmed the significant upregulation of MAPK1 and NF-κB,key genes in the MAPK signaling pathway.Conclusion:This study reveals the m^(6)A modification patterns of lncRNAs in middle ear cholesteatoma,suggests a direction for further research into the role of lncRNA m^(6)A modification in the etiology of cholesteatoma.The findings provide potential therapeutic targets for the treatment of middle ear cholesteatoma. 展开更多
关键词 long non-coding RNA m6A modifications middle ear cholesteatoma
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“Big Middle”:国外零售业演化理论新发展 被引量:3
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作者 韩耀 《世界经济与政治论坛》 CSSCI 北大核心 2008年第1期112-118,共7页
以计算机信息及其网络技术为代表的新技术革命带来社会经济的巨大变革,在这一背景下,零售业的演化路径也发生了改变,由原来的向"低价格水平"或"高服务水平"的两极化发展转变为向"较低的价格和较高的服务"... 以计算机信息及其网络技术为代表的新技术革命带来社会经济的巨大变革,在这一背景下,零售业的演化路径也发生了改变,由原来的向"低价格水平"或"高服务水平"的两极化发展转变为向"较低的价格和较高的服务"的中间化发展,由此形成了一个新的以现代技术,尤其是信息、网络技术为支撑的"大规模中间市场"。本文在介绍关于零售业演化的"Big Middle"理论的基础上,对于"Big Middle"的形成机理进行了分析,进而从技术进步的角度说明"Big Middle"形成的条件,并就"Big Middle"与信息技术的应用之间的关系进行了探讨。 展开更多
关键词 零售业 BIG middle 市场空间 信息技术
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Mechanical characteristics of intact Middle Pleistocene Epoch loess in northwestern China 被引量:4
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作者 钟祖良 刘新荣 《Journal of Central South University》 SCIE EI CAS 2012年第4期1163-1168,共6页
In order to research the mechanical characteristics of intact Middle Pleistocene Epoch loess, triaxial shear tests and isotonic compression test of intact Middle Pleistocene Epoch loess were conducted by improved SJ-I... In order to research the mechanical characteristics of intact Middle Pleistocene Epoch loess, triaxial shear tests and isotonic compression test of intact Middle Pleistocene Epoch loess were conducted by improved SJ-IA triaxial shear equipment. According to test results, it can be found that the intact Middle Pleistocene Epoch loess has the properties of shear dilatancy and shear shrinkage. With the increase of confining pressure, stress-strain curve develops from softening to hardening. The failure mode of intact Middle Pleistocene Epoch loess is shear failure with the rupture angle between 55° and 61°. And it is better to determine the yield stress (py, qy) of the intact loess under different confining pressures by using the εv-q/p curve. Along with the increase of confining pressure, yield deviatoric stress qy and yield spherical stress py present logarithmic relationship. Besides, the strength parameters, elastic modulus K and G of intact loess, are obtained, which are benefit for loess projects design. 展开更多
关键词 yield stress compression testing failure model middle Pleistocene Epoch loess
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Advances in the study of the Middle and Upper Atmosphere 被引量:3
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作者 CHEN Zeyu CHEN Hongbin 《空间科学学报》 CAS CSCD 北大核心 2004年第z1期128-133,共6页
The research activities of the middle and upper atmosphere in China paced abig stride in the recent years. This paper provides an brief overview of theadvances in main aspects of the study in China during the past fou... The research activities of the middle and upper atmosphere in China paced abig stride in the recent years. This paper provides an brief overview of theadvances in main aspects of the study in China during the past four years. 展开更多
关键词 middle and UPPER ATMOSPHERE
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THE FIRST DISCOVERY OF MIDDLE MIOCENE RODENTS FROM THE NORTHERN JUNGGAR BASIN, CHINA 被引量:4
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《古脊椎动物学报》 1988年第4期259-264,共6页
During the field season of 1982 in Northern Junggar Basin, surface collecting by the field party of IVPP at the outcrops of Halamagai Formation provided 7 isolated cheek teeth of rodents associated with some macromamm... During the field season of 1982 in Northern Junggar Basin, surface collecting by the field party of IVPP at the outcrops of Halamagai Formation provided 7 isolated cheek teeth of rodents associated with some macromammals typical of middle Miocene age: Platybelodon, Stephanocemas thomsoni, Lagomeryx sp., etc.It is the first time that the Miocene rodents are discovered in this region. They belong to 3 genera, 4 species:Sinomylagaulus halamagaiensis gen. et sp. nov.Atlantoxerus junggarensis sp. nov.A. giganteus sp. nov.Amblycastor tungurensis Stirton, 1934Many thanks are due to Drs. V. Fahlbusch, N. Schmidt-Kittler, P. Mein and N. S. Shevyreva for their sending me the comparative materials, reprints and profitable discussion. The colleagues of IVPP field party put in a lot of hard work to collect this material. Mr. Shen Wenlong made the textfigures. To all these persons the author wants to express her heartfelt gratitudes.All the specimens herein described are stored in the collections of IVPP. 展开更多
关键词 Northern Junggar Basin middle Miocene Lower Halamagai Formation RODENTIA
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Advances in the Studies of the Middle and Upper Atmosphere in 2004-2006 被引量:6
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作者 CHEN Zeyu LIU Renqiang +4 位作者 CHEN Hongbin CHEN Wen LU Daren XU Jiyao HU Xiong 《空间科学学报》 CAS CSCD 北大核心 2006年第z1期61-70,共10页
This paper summarizes the research results obtained by Chinese scientists and/or through international collaborations during 2004 to 2006.Within the context of COSPAR,the progresses in the studies of the middle and up... This paper summarizes the research results obtained by Chinese scientists and/or through international collaborations during 2004 to 2006.Within the context of COSPAR,the progresses in the studies of the middle and upper atmosphere in China in the past two years are introduced with focusing the developments in facilities and instruments,and the advancements in scientific issues,e.g.,dynamics related processes,atmospheric constituents,and the coupling with the lower atmosphere. 展开更多
关键词 middle and upper atmosphere
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Advances in the Researches of the Middle and Upper Atmosphere in China in 2012–2014 被引量:1
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作者 CHEN Zeyu CHEN Hongbin +11 位作者 XU Jiyao BIAN Jianchun QIE Xiushu Lü Daren CHEN Wen REN Rongcai ZHANG Shaodong DOU Xiankang LI Tao HU Xiong HU Yongyun TIAN Wenshou 《空间科学学报》 CAS CSCD 北大核心 2014年第5期669-687,共19页
In this report we summarize the research results by Chinese scientists in 2012–2014. The focuses are placed on the researches of the middle and upper atmosphere, specifically the researches related to ground-based ob... In this report we summarize the research results by Chinese scientists in 2012–2014. The focuses are placed on the researches of the middle and upper atmosphere, specifically the researches related to ground-based observation capability development, dynamical processes, the property of circulation and chemistry-climate coupling of the middle atmospheric layers. 展开更多
关键词 middle and UPPER ATMOSPHERE Composition Structure Dynamics INFRASTRUCTURE Monitoring CAMPAIGN
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Middle range wireless power transfer systems with multiple resonators 被引量:1
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作者 陈新 张桂香 《Journal of Central South University》 SCIE EI CAS CSCD 2015年第6期2127-2136,共10页
The equivalent two-port network model of a middle range wireless power transfer(WPT) system was presented based on strongly coupled multiple resonators. The key parameters of the WPT system include self-inductance, re... The equivalent two-port network model of a middle range wireless power transfer(WPT) system was presented based on strongly coupled multiple resonators. The key parameters of the WPT system include self-inductance, resistance, parasitic capacitance, mutual inductance and S-parameters of coils & resonators were analyzed. The impedance matching method was used to optimize load power and transmission efficiency of the multi-resonator WPT system, and the impedance matching method was realized through adjusting the distances between the coils and resonators. Experiments show that the impedance matching method can effectively improve load power and transmission efficiency for middle range wireless power transfer systems with multiple resonators, at distances up to 3 times the coil radius with efficiency more than 70% and load power also close to 3.5 W. 展开更多
关键词 wireless power transfer middle range multiple resonators S-PARAMETERS two-port network impedance matching
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ADVANCES ON STUDY OF MIDDLE AND UPPER ATMOSPHERE AND THEIR COUPLING WITH LOWER ATMOSPHERE 被引量:1
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作者 LU Daren YI Fan XU Jiyao 《空间科学学报》 CAS CSCD 北大核心 2002年第z1期111-119,共9页
In this paper advances on study of middle and upper atmosphere and their cou pling with lower atmosphere in China in recent two years are briefly reviewed.This review emphasized three aspects, ie. (1) analysis and obs... In this paper advances on study of middle and upper atmosphere and their cou pling with lower atmosphere in China in recent two years are briefly reviewed.This review emphasized three aspects, ie. (1) analysis and observation of mid and upper atmosphere over China; (2) theoretical and modelling study of grav ity wave activities in middle atmosphere and their relation to lower atmospheric processes; (3) coupling between the stratosphere and troposphere. 展开更多
关键词 middle atmosphere GRAVITY waves Stratosphere-Troposphere Exchange(STE)
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THE EVOLUTION OF LANPING RIFT BASIN FROM LADINIAN IN MIDDLE TRIASSIC EPOCH TO EARLY JURASSIC EPOCH
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作者 Zhu Lidong,Wang Chengshan,Liu Dengzhong 《地学前缘》 EI CAS CSCD 2000年第S1期290-290,共1页
Lanping basin was a massif (land massif) in late Palaeozoic Era. The ocean of Jinshajiang separated it from Yangtze plate in east. Lancangjiang ocean separated it from Yunnan—Tibet plate in west. From late Permian Ep... Lanping basin was a massif (land massif) in late Palaeozoic Era. The ocean of Jinshajiang separated it from Yangtze plate in east. Lancangjiang ocean separated it from Yunnan—Tibet plate in west. From late Permian Epoch, the oceanic crust of Jinshajiang subduced the west from east, the one of Lancangjiang down went the east from west, and then the Yunnan—Tibet ancient land gradually closed to the Yangtze. In the end of the Permian Period, two continents and Lanping plate touched together, and the evolution history of the Paleotethys was end. Hercynian orogenic belt in the east and west sides of Lanping had volcanic rock colliding in early—middle Triassic Epoch. In Ladinian in middle Triassic and Carnian in late Triassic, the north side of Lanping basin formed the serial volcanic rock of spilite—quartz keratophyre because mantle\|derived magma causing by delamination rose and mixed with the constituent of continental crust. The volcanic rock overlapped the middle Triassic and late Palaeozoic stratum in angular unconformity. It was the feature of double peak or evolution from the basic to the acid. The race element distribution of volcanic rock was same as the one of tholeiite in island and inter\|arc basin. The rate of lead isotope of the volcanic rock was much higher. These points all distributed above the NHRL in Pb\|Pb. This indicated that the Pb of volcanic rock was the mantle\|derived magma mixed with crust one. The large\|area progression in Lanping rift basin begun in late Carnian.. The east side in Lanping basin developed the sedimentary system that was granule gravel (grit) rock in border facies—limestone in beach facies—black shale, and the middle had black shale, banded siliceous rock, brecciform limestone in late Carnian to Norian. The geochemistry research of siliceous rock showed that the genesis of the chert was hot water. The development of brecciform limestone was related with action of central\|axis rift. The Lanping rift basin went into consuming stage in Rhaetian Epoch of the late Triassic. The basin developed clastic rock bearing coal of continental\|oceanic alternation facies. In early Jurassic, the sedimentary area atrophied further, and the fine lacustrine sediment whose thickness was not great developed in the east of central\|axis. The west stratum of the basin in late Triassic Epoch touched directly with the one in middle Jurassic. Lanping basin was going into another evolution stage that was down\|warped basin. 展开更多
关键词 Lanping RIFT basin LADINIAN in middle TRIASSIC to early JU rassic EPOCH
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Middle Jurassic Palaeoclimatic Conditions as Inferred by the Diverse Fossil Wood Floras in Beipiao,Western Liaoning,China
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作者 Zikun Jiang~(1,2),Yongdong Wang~1,Ning Tian~2 1.Nanjing Institute of Geology and Paleontology,Chinese Academy of Sciences,Nanjing 210008,China. 2.Graduate School of Chinese Academy of Sciences,Beijing 100049,China 《地学前缘》 EI CAS CSCD 北大核心 2009年第S1期259-259,共1页
The Middle Jurassic system is well developed and exposed in western Liaoning Province including two formations,the Tiaojishan Formation and the Haifanggou Formation.The Tiaojishan Formation is represented by intermedi... The Middle Jurassic system is well developed and exposed in western Liaoning Province including two formations,the Tiaojishan Formation and the Haifanggou Formation.The Tiaojishan Formation is represented by intermediate extrusive and pyroclastic rocks,with intercalations of basic volcanic and sedimentary rocks.Diverse silicified wood specimens were recovered from this formation in Lamaying, 展开更多
关键词 FOSSIL wood PALAEOCLIMATE middle JURASSIC Tiaojishan Formation western LIAONING
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REVIEW OF MIDDLE AND UPPER ATMOSPHERIC RESEARCH IN CHINA
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作者 WANG Ying-jian(Center for Space Science and Applied Researeh,The Chinese Academy of Sciences, Beijing 100080) 《空间科学学报》 CAS CSCD 北大核心 1998年第S1期53-60,共8页
In past two years, the studies of planetary waves, gravity waves, photochemical processes and effects of solar and human activities in China have made encouraging progress. Some new instruments, e.g., VHF radar, sodiu... In past two years, the studies of planetary waves, gravity waves, photochemical processes and effects of solar and human activities in China have made encouraging progress. Some new instruments, e.g., VHF radar, sodium lidar,mesospheric microwave measurements and tilting filter photometer etc., have bring into operation, it enhances the observing ability to middle and upper atn1osphere greatly. In this paper main progress of the research in the upper stratosphere, mesosphere and lower thermosphere in China in the past two years is reviewed. 展开更多
关键词 middle and UPPER ATMOSPHERE middle ATMOSPHERIC dynamics middle ATMOSPHERIC PHOTOCHEMISTRY ATMOSPHERIC REMOTE sensing
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Clay Minerals of the Middle Jurassic Through Lower Cretaceous in Guangyuan Area,Northern Sichuan:Implications to Paleoclimate
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作者 Ke Cao~1,Xianghui Li~2 1.School of Earth Sciences and Resources,China University of Geosciences(Beijing),Beijing 100083,china. 2.Nanjing University,Nanjing 210093,China 《地学前缘》 EI CAS CSCD 北大核心 2009年第S1期111-111,共1页
Clay mineral analyses of the Middle Jurassic through the Early Cretaceous sedimentary rocks from the Guangyuan-Jian’ge section,Sichuan Basin (southwestern China)were undertaken in this article, which is aiming to rec... Clay mineral analyses of the Middle Jurassic through the Early Cretaceous sedimentary rocks from the Guangyuan-Jian’ge section,Sichuan Basin (southwestern China)were undertaken in this article, which is aiming to reconstruct the palaeoclimate of the area.Relative contents of the four clay minerals, smectite(25.8%-1.0%-46.8%),kaolinite(31.0%- 12.5%-12.6%),illite(31.3%-68.0%-28.0%)and chlorite(11.8%-8.5%-12.6%),as the target clay minerals,illite crystalline index(0.26-0.31-0.27)and chemical index(0.62-0.66-0.79)are used as indicator of paleoclimate.It is indicated that changes of 展开更多
关键词 middle Jurassic-Early CRETACEOUS clay mineral climate SICHUAN Basin
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The Paleogeographic Reconstruction for the Central Regions of the Western Siberian Basin in the Middle Jurassic Epoch
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作者 Aleksey Yu.Popov Lyudmila G.Vakulenko Valeriy A.Kazanenkov 《地学前缘》 EI CAS CSCD 北大核心 2009年第S1期193-193,共1页
The complex investigation of the Bathonian sedimentary deposits in central regions of the WestSiberian basin was done.On the basis both of lithofacial analysis of core clefts and the geophysical investigation data and... The complex investigation of the Bathonian sedimentary deposits in central regions of the WestSiberian basin was done.On the basis both of lithofacial analysis of core clefts and the geophysical investigation data and taking into account the tectonic features of the Jurassic structural storey the sedimenttological model of deposits was built and the main regularities of its building were identified.At the initial stage the framework of alluvial lower plain 展开更多
关键词 PALEOGEOGRAPHY LITHOLOGY sediment-tary environments middle JURASSIC Western Siberia
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Statistical inference for dependence competing risks model under middle censoring
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作者 WANG Yan SHI Yimin WU Min 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2019年第1期209-222,共14页
Middle censoring is an important censoring scheme,in which the actual failure data of an observation becomes unobservable if it falls into a random interval. This paper considers the statistical analysis of the depend... Middle censoring is an important censoring scheme,in which the actual failure data of an observation becomes unobservable if it falls into a random interval. This paper considers the statistical analysis of the dependent competing risks model by using the Marshall-Olkin bivariate Weibull(MOBW) distribution.The maximum likelihood estimations(MLEs), midpoint approximation(MPA) estimations and approximate confidence intervals(ACIs) of the unknown parameters are obtained. In addition, the Bayes approach is also considered based on the Gamma-Dirichlet prior of the scale parameters, with the given shape parameter.The acceptance-rejection sampling method is used to obtain the Bayes estimations and construct credible intervals(CIs). Finally,two numerical examples are used to show the performance of the proposed methods. 展开更多
关键词 middle CENSORING DEPENDENT competing RISKS model Marshall-Olkin BIVARIATE Weibull (MOBW) distribution acceptancerejection sampling.
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Advances in Researches on the Middle and Upper Atmosphere in 2010—2012
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作者 CHEN Zeyu CHEN Hongbin +5 位作者 LIU Xiao HU Xiong BIAN Jianchu CHEN Wen ZHANG Shaodong XUE Xianghui 《空间科学学报》 CAS CSCD 北大核心 2012年第5期681-692,共12页
This article summarizes the researches on the middle and upper atmosphere by Chinese scientists in 2010-2012.The focuses are placed on the advances in construction of ground-based remote sensing facilities,the mean st... This article summarizes the researches on the middle and upper atmosphere by Chinese scientists in 2010-2012.The focuses are placed on the advances in construction of ground-based remote sensing facilities,the mean state and long-term changes in the middle atmosphere circulation, the prevailing dynamical processes,and the coupling of the middle atmospheric layers. 展开更多
关键词 Upper atmosphere middle atmosphere STRATOSPHERE Troposphere COUPLING
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The Sustainable Utilization of Lake Resources in the Middle and Lower Reaches of Yangtze River
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作者 CAO Jian tingDoctor, College of Water Resources and Environment, Hohai University, Nanjing 210098, China WANG Su minProfessor, Nanjing Institute of Geography and Limnology, Chinese Academy of Sciences, Nanjing 210008, China 《人民长江》 北大核心 2001年第S1期57-60,共4页
Based on geographical and hydrological characteristics of lakes in the middle and lower reaches of Yangtze River, this paper analyzes the factors restricting the sustainable utilization of lake resources, including th... Based on geographical and hydrological characteristics of lakes in the middle and lower reaches of Yangtze River, this paper analyzes the factors restricting the sustainable utilization of lake resources, including the conflict among agriculture water conservancy, and fishery, lake water pollution and eutrophication, lake siltation and swamping. The countermeasures and suggestions, such as improving the strategic status of lake harnessing, strengthening integrated management of lakes and their watershed, strengthening researches on lake environment and lake resources, are proposed to practice the sustainable utilization of lake resources. 展开更多
关键词 LAKE RESOURCES harnessing integrated management middle and lower reaches of YANGTZE River
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Advances in the Researches of the Middle and Upper Atmosphere in China
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作者 CHEN Zeyu CHEN Hongbin +8 位作者 XU Jiyao HUANG Kaiming XUE Xianghui HU Dingzhu CHEN Wen YANG Guotao TIAN Wenshou HU Yongyun XIA Yan 《空间科学学报》 CAS CSCD 北大核心 2020年第5期856-874,共19页
In this report we summarize the research results by Chinese scientists in 2018–2020.The focuses are placed on the researches of the middle and upper atmosphere,specifically the researches on atmospheric structure and... In this report we summarize the research results by Chinese scientists in 2018–2020.The focuses are placed on the researches of the middle and upper atmosphere,specifically the researches on atmospheric structure and composition,climate and chemistry-climate coupling and climate modelling,dynamics in particular those inducing the coupling of the atmospheric layers. 展开更多
关键词 middle and upper atmosphere Structure and composition CLIMATE Layer coupling
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Advances in the Researches of the Middle and Upper Atmosphere in China in 2020-2022
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作者 CHEN Zeyu XU Jiyao +14 位作者 CHEN Hongbin CHEN Wen REN Rongcai HU Xiong ZHU Yajun XUE Xianghui LU Gaopeng ZHANG Shaodong HUANG Kaiming TIAN Wenshou ZHANG Jiankai HU Dingzhu RAO Jian HU Yongyun XIA Yan 《空间科学学报》 CAS CSCD 北大核心 2022年第4期684-711,共28页
This report reviews the researches for the middle and upper atmosphere in 2020-2022 by Chinese scientists.The report consists of five parts introducing primarily the results from the aspects of the development of infr... This report reviews the researches for the middle and upper atmosphere in 2020-2022 by Chinese scientists.The report consists of five parts introducing primarily the results from the aspects of the development of infrastructure,the structure and composition,the climate and modeling,the dynamics for the middle and upper atmosphere,and Coupling between Stratosphere and Troposphere,respectively. 展开更多
关键词 middle and upper atmosphere Structure and composition CLIMATE DYNAMICS
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Advances in the Researches of the Middle and Upper Atmosphere in China
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作者 CHEN Zeyu CHEN Hongbin +13 位作者 XU Jiyao LU Daren ZHANG Shaodong XUE Xianghui TIAN Wenshou LIU Renqiang CHEN Wen HU Yongyun WANG Rui HU Dingzhu HU Xiong YANG Guotao GONG Yun LU Gaopeng 《空间科学学报》 CAS CSCD 北大核心 2018年第5期763-780,共18页
In this paper we summarize the research results by Chinese scientists in 2016–2018. The focuses are placed on the researches of the middle and upper atmosphere, specifically the researches associated with groundbased... In this paper we summarize the research results by Chinese scientists in 2016–2018. The focuses are placed on the researches of the middle and upper atmosphere, specifically the researches associated with groundbased observation capability development, dynamical processes, and properties of circulation and chemistryclimate coupling of the middle atmospheric layers. 展开更多
关键词 middle and upper atmosphere Dynamical and micro-physical-chemical process Observation infrastructure
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