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The construction of polycistronic retroviral vector
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作者 Guan-Hua Lai, Shi-Shu ChenResearch Center for Human Gene Therapy, ShanghaiSecond Medical University, Shanghai 200025 《中国实验血液学杂志》 CAS CSCD 1997年第3期332-332,共1页
Objective: In order to coordinately express amarker gene and therapeutic genes in one vector, apolycistronic retroviral vector was constructed withthe internal ribosome entry site from encephalo-myocarditis and polio ... Objective: In order to coordinately express amarker gene and therapeutic genes in one vector, apolycistronic retroviral vector was constructed withthe internal ribosome entry site from encephalo-myocarditis and polio virus, which was able to expressthree different genes simultaneously. Methods: Thevector used mouse moloney leukemia virus sequencesfor viral expression and packaging functions 展开更多
关键词 RIBOSOME encephalo packaging entry myocarditis HEPATOMA PRODUCER TITER PROMOTER capable
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