Objective According to the report from American Heart Association(AHA),cardiovascular diseases(CVDs)are the leading causes of death globally,and coronary artery disease(CAD),known as coronary atherosclerotic plaques,a...Objective According to the report from American Heart Association(AHA),cardiovascular diseases(CVDs)are the leading causes of death globally,and coronary artery disease(CAD),known as coronary atherosclerotic plaques,accounts for over 30%of cardiovascular diseases.Therefore,it is of great clinical significance to study the relationship between coronary bifurcations morphometrical feature change and coronary artery disease.Although coronary atherosclerosis has been extensively investigated,there is a lack of in-deep study on the differences in morphometric features between optimal and realistic geometry of coronary arterial trees.The purpose of the present paper is to determine the morphological changes in patients with CAD lesion compared with non-coronary artery disease(non-CAD)subjects.Methods Due to the difficulty of studying the coronary bifurcations in vivo,image-based in vitro anatomical 3D models have been widely used as a noninvasive method for morphometric measurement and clinical diagnosis of the coronary bifurcations.With the development of coronary computed tomography angiography(CTA)hardware and software technologies,the CTA imaging technique has been shown a promising application in the characterization,visualization,and identification of coronary artery disease in recent decades.The CTA images used to reconstruct three-dimensional(3D)coronary arterial trees are from Asia populations(Southern Chinese populations),including five cadavers without CAD lesion and 102 patients with CAD lesion.The best fit artery diameter was calculated as twice the average radius between the points in the centerlines and the points on the coronary arterial inner wall.The bifurcation angles between larger daughter artery and smaller daughter artery were determined by the intersection angle of their centerlines.Murray’s law was introduced to assess the deviation of the realistic vascular networks from its optimal state.Results Based on the morphometric analysis of coronary artery bifurcations in non-CAD subjects and patients with CAD lesion subjects,the most important finding is that morphological feature parameters of non-CAD subjects are closer to the optimal values than those of patients with CAD lesion.Moreover,by comparing the morphometric data between the left and right coronary arteries,the right coronary artery exhibits a structure closer to the optimal one in morphological feature than the left coronary artery.In addition,coronary arterial trees with CAD lesion have higher asymmetry and larger area expansion ratio(AER)than those of the coronary arterial trees without CAD lesion.Conclusions We morphologically found that the coronary arterial trees with CAD lesion and left are more likely to deviate from the optimal structure predicted by Murray’s law than those without CAD lesion and right.The degree to which coronary arterial system deviating from their optimal state may directly affect the incidence of coronary artery disease.This computer morpho-logical analysis strategy is illustrated to be effective in the distinguishing of the geometric differences between the healthy and diseased coronary arteries,and the analysis method may have a large potential in cardiovascular disease earlier diagnosis.展开更多
A relatively well-preserved rodent fossil,including its incisors,cheek teeth,and postcranial skeleton,was collected from the Baiyin Obo in Siziwang Banner,Nei Mongol.A multifaceted research approach was undertaken in ...A relatively well-preserved rodent fossil,including its incisors,cheek teeth,and postcranial skeleton,was collected from the Baiyin Obo in Siziwang Banner,Nei Mongol.A multifaceted research approach was undertaken in this study to conduct a comprehensive analysis on the newly discovered specimen.Based on a morphological comparison,the new specimen was identified as Hulgana cf.H.ertnia within the Ischyromyidae family.Incisive enamel microstructure analysis revealed the typical pauciserial enamel structure of Hulgana.Bone histological analysis indicates that the specimen represents a juvenile individual,which is consistent with the ontogenetic stage indicated by dental developmental stage and wear pattern.The application of geometric morphometrics to the calcaneus and bone histology of the femur and phalanx further substantiates the taxonomic classification of Hulgana as a terrestrial and cursorial rodent,exhibiting a degree of fossorial ability.This classification is analogous to that of certain extant cricetids and ground squirrels.展开更多
This research compares submarine morphology with seismic reflection profiles as they manifest tectonics in a rapidly transform continental margin (Monterey Bay,California).We study modern submarine processes integrati...This research compares submarine morphology with seismic reflection profiles as they manifest tectonics in a rapidly transform continental margin (Monterey Bay,California).We study modern submarine processes integrating seismic reflection profiles interpretation,slope stability and liquefaction potential analyses and geomorphic change obtained by using high-resolution multibeam展开更多
A study on the food and feeding habit of Chrysichthys nigrodigitatus （Lacepede） was conducted in River Niger within the region of Oshimili local government area of Delta State Nigeria. A total of 90 specimens were c...A study on the food and feeding habit of Chrysichthys nigrodigitatus （Lacepede） was conducted in River Niger within the region of Oshimili local government area of Delta State Nigeria. A total of 90 specimens were collected with the help of fishermen using gill net, cast net and traps. The fish samples were immediately taken to the laboratory for analysis. Morphometric characteristics such as weight, length, condition factor, egg weight, Gonado Somatic Index （GSI） and sex ratio were determined. The stomach content was analyzed using numerical method to determine the food content. The total length of the fish sampled ranged from 14.40-44.60 cm, while the standard length varied from 11.00 cm to 47.00 cm and the fish body weight ranged between 19.00 g to 503.20 g. Sex ratio 1 female to 1 male was observed. The mean condition factor for both male and female obtained was 1.67. Of all the 90 fishes sampled, none had empty gut representing 100%. The major food items were phytoplankton, plant part and Detritus. Out of 41 females sampled, only 17 had eggs and the eggs were matured at stage IV.展开更多
基金sponsored by the National Natural Science Foundation of China ( 11432006 ( J. Wu) , 11672109 ( Y. Fang) and 31500759 ( J. Lin) )the Fundamental Research Funds for the Central Universities
文摘Objective According to the report from American Heart Association(AHA),cardiovascular diseases(CVDs)are the leading causes of death globally,and coronary artery disease(CAD),known as coronary atherosclerotic plaques,accounts for over 30%of cardiovascular diseases.Therefore,it is of great clinical significance to study the relationship between coronary bifurcations morphometrical feature change and coronary artery disease.Although coronary atherosclerosis has been extensively investigated,there is a lack of in-deep study on the differences in morphometric features between optimal and realistic geometry of coronary arterial trees.The purpose of the present paper is to determine the morphological changes in patients with CAD lesion compared with non-coronary artery disease(non-CAD)subjects.Methods Due to the difficulty of studying the coronary bifurcations in vivo,image-based in vitro anatomical 3D models have been widely used as a noninvasive method for morphometric measurement and clinical diagnosis of the coronary bifurcations.With the development of coronary computed tomography angiography(CTA)hardware and software technologies,the CTA imaging technique has been shown a promising application in the characterization,visualization,and identification of coronary artery disease in recent decades.The CTA images used to reconstruct three-dimensional(3D)coronary arterial trees are from Asia populations(Southern Chinese populations),including five cadavers without CAD lesion and 102 patients with CAD lesion.The best fit artery diameter was calculated as twice the average radius between the points in the centerlines and the points on the coronary arterial inner wall.The bifurcation angles between larger daughter artery and smaller daughter artery were determined by the intersection angle of their centerlines.Murray’s law was introduced to assess the deviation of the realistic vascular networks from its optimal state.Results Based on the morphometric analysis of coronary artery bifurcations in non-CAD subjects and patients with CAD lesion subjects,the most important finding is that morphological feature parameters of non-CAD subjects are closer to the optimal values than those of patients with CAD lesion.Moreover,by comparing the morphometric data between the left and right coronary arteries,the right coronary artery exhibits a structure closer to the optimal one in morphological feature than the left coronary artery.In addition,coronary arterial trees with CAD lesion have higher asymmetry and larger area expansion ratio(AER)than those of the coronary arterial trees without CAD lesion.Conclusions We morphologically found that the coronary arterial trees with CAD lesion and left are more likely to deviate from the optimal structure predicted by Murray’s law than those without CAD lesion and right.The degree to which coronary arterial system deviating from their optimal state may directly affect the incidence of coronary artery disease.This computer morpho-logical analysis strategy is illustrated to be effective in the distinguishing of the geometric differences between the healthy and diseased coronary arteries,and the analysis method may have a large potential in cardiovascular disease earlier diagnosis.
文摘A relatively well-preserved rodent fossil,including its incisors,cheek teeth,and postcranial skeleton,was collected from the Baiyin Obo in Siziwang Banner,Nei Mongol.A multifaceted research approach was undertaken in this study to conduct a comprehensive analysis on the newly discovered specimen.Based on a morphological comparison,the new specimen was identified as Hulgana cf.H.ertnia within the Ischyromyidae family.Incisive enamel microstructure analysis revealed the typical pauciserial enamel structure of Hulgana.Bone histological analysis indicates that the specimen represents a juvenile individual,which is consistent with the ontogenetic stage indicated by dental developmental stage and wear pattern.The application of geometric morphometrics to the calcaneus and bone histology of the femur and phalanx further substantiates the taxonomic classification of Hulgana as a terrestrial and cursorial rodent,exhibiting a degree of fossorial ability.This classification is analogous to that of certain extant cricetids and ground squirrels.
文摘This research compares submarine morphology with seismic reflection profiles as they manifest tectonics in a rapidly transform continental margin (Monterey Bay,California).We study modern submarine processes integrating seismic reflection profiles interpretation,slope stability and liquefaction potential analyses and geomorphic change obtained by using high-resolution multibeam
文摘A study on the food and feeding habit of Chrysichthys nigrodigitatus （Lacepede） was conducted in River Niger within the region of Oshimili local government area of Delta State Nigeria. A total of 90 specimens were collected with the help of fishermen using gill net, cast net and traps. The fish samples were immediately taken to the laboratory for analysis. Morphometric characteristics such as weight, length, condition factor, egg weight, Gonado Somatic Index （GSI） and sex ratio were determined. The stomach content was analyzed using numerical method to determine the food content. The total length of the fish sampled ranged from 14.40-44.60 cm, while the standard length varied from 11.00 cm to 47.00 cm and the fish body weight ranged between 19.00 g to 503.20 g. Sex ratio 1 female to 1 male was observed. The mean condition factor for both male and female obtained was 1.67. Of all the 90 fishes sampled, none had empty gut representing 100%. The major food items were phytoplankton, plant part and Detritus. Out of 41 females sampled, only 17 had eggs and the eggs were matured at stage IV.
