慢性病患者的长期管理是基层医疗的核心任务之一,患者的规律随访(TR)与疾病预后密切相关。近期Annals of Family Medicine刊发了一篇文章《Teamwork among Primary Care Staff to Achieve Regular Follow-Up of Chronic Patients》,该...慢性病患者的长期管理是基层医疗的核心任务之一,患者的规律随访(TR)与疾病预后密切相关。近期Annals of Family Medicine刊发了一篇文章《Teamwork among Primary Care Staff to Achieve Regular Follow-Up of Chronic Patients》,该文章指出慢性病患者的TR面临多重挑战,既往研究多聚焦于患者个体因素,而忽视了医疗团队动态对随访率的潜在影响。展开更多
Creutzfeldt-Jakob disease(CJD)is a rare neurodegenerative disorder characterized by abnormalities in the prion protein(PrP),the most common form of human prion disease.Although Genome-Wide Association Studies(GWAS)hav...Creutzfeldt-Jakob disease(CJD)is a rare neurodegenerative disorder characterized by abnormalities in the prion protein(PrP),the most common form of human prion disease.Although Genome-Wide Association Studies(GWAS)have identified numerous risk genes for CJD,the mechanisms underlying these risk loci remain poorly understood.This study aims to elucidate novel genetically prioritized candidate proteins associated with CJD in the human brain through an integrative analytical pipeline.Utilizing datasets from Protein Quantitative Trait Loci(pQTL)(NpQTL1=152,NpQTL2=376),expression QTL(eQTL)(N=452),and the CJD GWAS(NCJD=4110,NControls=13569),we implemented a systematic analytical pipeline.This pipeline included Proteome-Wide Association Study(PWAS),Mendelian randomization(MR),Bayesian colocalization,and Transcriptome-Wide Association Study(TWAS)to identify novel genetically prioritized candidate proteins implicated in CJD pathogenesis within the brain.Through PWAS,we identified that the altered abundance of six brain proteins was significantly associated with CJD.Two genes,STX6 and PDIA4,were established as lead causal genes for CJD,supported by robust evidence(False Discovery Rate<0.05 in MR analysis;PP4/(PP3+PP4)≥0.75 in Bayesian colocalization).Specifically,elevated levels of STX6 and PDIA4 were associated with an increased risk of CJD.Additionally,TWAS demonstrated that STX6 and PDIA4 were associated with CJD at the transcriptional level.展开更多
植物硝酸盐转运蛋白(Nitrate transporter,NRT)可有效转运NO-3,提升氮素利用效率。为了解析草地早熟禾(Poa pratensis)适应不同浓度及不同形态氮素、干旱胁迫机理,本研究以草地早熟禾为试材,对NRT1/PTR FAMILY 8.3基因进行克隆、生物信...植物硝酸盐转运蛋白(Nitrate transporter,NRT)可有效转运NO-3,提升氮素利用效率。为了解析草地早熟禾(Poa pratensis)适应不同浓度及不同形态氮素、干旱胁迫机理,本研究以草地早熟禾为试材,对NRT1/PTR FAMILY 8.3基因进行克隆、生物信息学分析,并分析了不同浓度及不同形态氮素以及干旱下该基因表达情况。研究结果:草地早熟禾NRT1/PTR FAMILY 8.3基因包含典型的主要协同转运蛋白超家族(Major facilitator superfamily,MFS)结构域,与二穗短柄草(Brachypodium distachyon)高度同源;荧光定量PCR分析表明,该基因根部、叶部的表达量显著高于茎部;氮浓度为7.5 mM时,不同形态氮素诱导下,NaNO3处理组有利于该基因表达;无氮、高氮组(0,15 mM NaNO3)基因的表达量显著高于适氮组(7.5 mM NaNO3);干旱胁迫可促进其表达。研究结果为探究NRT1/PTR FAMILY 8.3在不同氮素环境中的调节机制,培育氮素利用率高的优质草种提供理论基础。展开更多
In a manufacturing industry, mixed model assembly line(MMAL) is preferred in order to meet the variety in product demand. MMAL balancing helps in assembling products with similar characteristics in a random fashion. T...In a manufacturing industry, mixed model assembly line(MMAL) is preferred in order to meet the variety in product demand. MMAL balancing helps in assembling products with similar characteristics in a random fashion. The objective of this work aims in reducing the number of workstations, work load index between stations and within each station. As manual contribution of workers in final assembly line is more, ergonomics is taken as an additional objective function. Ergonomic risk level of a workstation is evaluated using a parameter called accumulated risk posture(ARP), which is calculated using rapid upper limb assessment(RULA) check sheet. This work is based on the case study of an MMAL problem in Rane(Madras) Ltd.(India), in which a problem based genetic algorithm(GA) has been proposed to minimize the mentioned objectives. The working of the genetic operators such as selection, crossover and mutation has been modified with respect to the addressed MMAL problem. The results show that there is a significant impact over productivity and the process time of the final assembled product, i.e., the rate of production is increased by 39.5% and the assembly time for one particular model is reduced to 13 min from existing 18 min. Also, the space required using the proposed assembly line is only 200 m2 against existing 350 m2. Further, the algorithm helps in reducing workers fatigue(i.e., ergonomic friendly).展开更多
This review article aims to give a comprehensive review of periodic orbits in the circular restricted three-body problem(CRTBP),which is a standard ideal model for the Earth-Moon system and is closest to the practical...This review article aims to give a comprehensive review of periodic orbits in the circular restricted three-body problem(CRTBP),which is a standard ideal model for the Earth-Moon system and is closest to the practical mechanical model.It focuses the attention on periodic orbits in the Earth-Moon system.This work is primarily motivated by a series of missions and plans that take advantages of the three-body periodic orbits near the libration points or around two gravitational celestial bodies.Firstly,simple periodic orbits and their classification that is usually considered to be early work before 1970 are summarized,and periodic orbits around Lagrange points,either planar or three-dimensional,are intensively studied during past decades.Subsequently,stability index of a periodic orbit and bifurcation analysis are presented,which demonstrate a guideline to find more periodic orbits inspired by bifurcation signals.Then,the practical techniques for computing a wide range of periodic orbits and associated quasi-periodic orbits,as well as constructing database of periodic orbits by numerical searching techniques are also presented.For those unstable periodic orbits,the station keeping maneuvers are reviewed.Finally,the applications of periodic orbits are presented,including those in practical missions,under consideration,and still in conceptual design stage.This review article has the function of bridging between engineers and researchers,so as to make it more convenient and faster for engineers to understand the complex restricted three-body problem(RTBP).At the same time,it can also provide some technical thinking for general researchers.展开更多
In order to overcome defects of the classical hidden Markov model (HMM), Markov family model (MFM), a new statistical model was proposed. Markov family model was applied to speech recognition and natural language proc...In order to overcome defects of the classical hidden Markov model (HMM), Markov family model (MFM), a new statistical model was proposed. Markov family model was applied to speech recognition and natural language processing. The speaker independently continuous speech recognition experiments and the part-of-speech tagging experiments show that Markov family model has higher performance than hidden Markov model. The precision is enhanced from 94.642% to 96.214% in the part-of-speech tagging experiments, and the work rate is reduced by 11.9% in the speech recognition experiments with respect to HMM baseline system.展开更多
The Myb family of proteins is a group offunctionally diverse transcriptional activatorsfound in both plants and animals that ischaracterized by a conserved DNA bindingdomain of approximately 50 amino acids.Inplants,My...The Myb family of proteins is a group offunctionally diverse transcriptional activatorsfound in both plants and animals that ischaracterized by a conserved DNA bindingdomain of approximately 50 amino acids.Inplants,Myb proteins are involved in control展开更多
MicroRNA（miRNA） is a class of important regulating non-coding small molecular RNA. The gma-MIR166 gene family consists of 21 members and their expression patterns diversify widely. It is important to analyze the evo...MicroRNA（miRNA） is a class of important regulating non-coding small molecular RNA. The gma-MIR166 gene family consists of 21 members and their expression patterns diversify widely. It is important to analyze the evolution of gma-MIR166 gene family in order to understand the evolutionary mechanisms of miRNAs in soybean. In this study, we implemented soybean wide genome block analysis, the molecular phylogeny of gma-MIR166 and block analysis of gma-MIR166 family. The results showed that both chromosome big segmental duplications and tandem duplications were main reasons contributed to the expanding of gmaMIR166 gene family. These findings suggested that gma-MIR166 gene family might originate from one or two ancient miRNA genes. The results of research provided a support for evolutionary study of miRNAs in soybean and related species in Fabaceae.展开更多
The ongoing need for better fuel economy and lower exhaust pollution of vehicles has increased the employment of electric power steering(EPS)in automotives.Optimal design of EPS for a product family reduces the develo...The ongoing need for better fuel economy and lower exhaust pollution of vehicles has increased the employment of electric power steering(EPS)in automotives.Optimal design of EPS for a product family reduces the development and fabrication costs significantly.In this paper,the TOPSIS method along with the NSGA-Ⅱis employed to find an optimum family of EPS for an automotive platform.A multi-objective optimization problem is defined considering road feel,steering portability,RMS of Ackerman error,and product family penalty function(PFPF)as the conflicting objective functions.The results for the single objective optimization problems and the ones for the multi-objective optimization problem,as well as two suggested trade-off design points are presented,compared and discussed.For the two suggested points,performance at one objective function is deteriorated by about 1%,while the commonality is increased by 20%–40%,which shows the effectiveness of the proposed method in first finding the non-dominated design points and then selecting the trade-off among the obtained points.The results indicate that the obtained trade-off points have superior performance within the product family with maximum number of common parts.展开更多
Let P（s, δ） be a sphere plant family described by the transfer function set where the coefficients of the denominator and numerator polynomials are affine in a real uncertain parameter vector δ satisfying the Eucl...Let P（s, δ） be a sphere plant family described by the transfer function set where the coefficients of the denominator and numerator polynomials are affine in a real uncertain parameter vector δ satisfying the Euclidean norm constraint ｜｜δ｜｜〈δ. The concept of stabilizability radius of P（s, δ） is introduced which is the norm bound δs for δ such that every member plant of P（s, δ） is stabilizable if and only if ｜｜δ｜｜〈δs. The stabilizability radius can be simply interpreted as the ＇largest sphere＇ around the nominal plant P（s,θ） such that P（s, δ） is stabilizable. The numerical method and the analytical method are presented to solve the stabilizability radius calculation problem of the sphere plants.展开更多
Background:Cotton(Gossypium hirsutum) provides the largest natural fiber for the textile manufacturing industries,but its production is on the decline due to the effects of salinity.Soil salt-alkalization leads to dam...Background:Cotton(Gossypium hirsutum) provides the largest natural fiber for the textile manufacturing industries,but its production is on the decline due to the effects of salinity.Soil salt-alkalization leads to damage in cotton growth and a decrease in yields.Hyperosmolality-gated calcium-permeable channels(OSCA) have been found to be involved in the detection of extracellular changes which trigger an increase in cytosolic free calcium concentration.Hyperosmolality-induced calcium ion increases have been widely speculated to be playing a role in osmosensing in plants.However,the molecular nature of the corresponding calcium ion channels remains unclearly.In this research work,we describe the OSCA genes and their putative function in osmosensing in plants by carrying out genomewide identification,characterization and functional analysis of the significantly up-regulated OSCA gene,GhOSCA1.1 through reverse genetics.Result:A total of 35,21 and 22 OSCA genes were identified in G.hirsutum,G.arboreum,and G.raimondii genomes,respectively,and were classified into four different clades according to their gene structure and phylogenetic relationship.Gene and protein structure analysis indicated that 35 GhOSCA genes contained a conserved RSN17 TM(PF02714) domain.Moreover,the cis-regulatory element analysis indicated that the OSCA genes were involved in response to abiotic stress.Furthermore,the knockdown of one of the highly up-regulated genes,GhOSCA1.1 showed that the virus-induced gene silenced(VIGS) plants were highly sensitive to dehydration and salinity stresses compared with the none VIGS plants as evident with higher concentration levels of oxidant enzymes compared with the antioxidant enzymes on the leaves of the stressed plants.Conclusion:This study provides the first systematic analysis of the OSCA gene family and will be important for understanding the putative functions of the proteins encoded by the OSCA genes in cotton.These results provide a new insight of defense responses in general and lay the foundation for further investigation of the molecular role played by the OSCA genes,thereby providing suitable approaches to improve crop performance under salinity and drought stress conditions.展开更多
Product family(PF) is the most important part of product platform. A new method is proposed to mine PF based on multi-space product data in PLM database. Product structure tree(PST) and bill of material(BOM) are used ...Product family(PF) is the most important part of product platform. A new method is proposed to mine PF based on multi-space product data in PLM database. Product structure tree(PST) and bill of material(BOM) are used as the data source. A PF can be obtained by mining physics space, logic space and attribute space of product data. In this work, firstly, a PLM database is described, consisting of data organization form, data structure, and data characteristics. Then the PF mining method introduces the sequence alignment techniques used in bio-informatics, which mainly includes data pre-processing, regularization, mining algorithm and cluster analysis. Finally, the feasibility and effectiveness of the proposed method are verified by a case study of high and middle pressure valve, demonstrating a feasible method to obtain PF from PLM database.展开更多
This essay studies various family-related factors that influence a child’s academic achievement in school in P.R. China. The factors are illustrated under three categories: the family’s social class and education, e...This essay studies various family-related factors that influence a child’s academic achievement in school in P.R. China. The factors are illustrated under three categories: the family’s social class and education, early home environment and family material condition. The author discusses the relevant factors by way of relating the knowledge of social environment to his own experiences as a student and then teacher in China. The essay closes with a discussion directing the public’s attention to the concern about home-related factors influencing a child’s academic achievements in school.展开更多
文摘慢性病患者的长期管理是基层医疗的核心任务之一,患者的规律随访(TR)与疾病预后密切相关。近期Annals of Family Medicine刊发了一篇文章《Teamwork among Primary Care Staff to Achieve Regular Follow-Up of Chronic Patients》,该文章指出慢性病患者的TR面临多重挑战,既往研究多聚焦于患者个体因素,而忽视了医疗团队动态对随访率的潜在影响。
文摘Creutzfeldt-Jakob disease(CJD)is a rare neurodegenerative disorder characterized by abnormalities in the prion protein(PrP),the most common form of human prion disease.Although Genome-Wide Association Studies(GWAS)have identified numerous risk genes for CJD,the mechanisms underlying these risk loci remain poorly understood.This study aims to elucidate novel genetically prioritized candidate proteins associated with CJD in the human brain through an integrative analytical pipeline.Utilizing datasets from Protein Quantitative Trait Loci(pQTL)(NpQTL1=152,NpQTL2=376),expression QTL(eQTL)(N=452),and the CJD GWAS(NCJD=4110,NControls=13569),we implemented a systematic analytical pipeline.This pipeline included Proteome-Wide Association Study(PWAS),Mendelian randomization(MR),Bayesian colocalization,and Transcriptome-Wide Association Study(TWAS)to identify novel genetically prioritized candidate proteins implicated in CJD pathogenesis within the brain.Through PWAS,we identified that the altered abundance of six brain proteins was significantly associated with CJD.Two genes,STX6 and PDIA4,were established as lead causal genes for CJD,supported by robust evidence(False Discovery Rate<0.05 in MR analysis;PP4/(PP3+PP4)≥0.75 in Bayesian colocalization).Specifically,elevated levels of STX6 and PDIA4 were associated with an increased risk of CJD.Additionally,TWAS demonstrated that STX6 and PDIA4 were associated with CJD at the transcriptional level.
文摘植物硝酸盐转运蛋白(Nitrate transporter,NRT)可有效转运NO-3,提升氮素利用效率。为了解析草地早熟禾(Poa pratensis)适应不同浓度及不同形态氮素、干旱胁迫机理,本研究以草地早熟禾为试材,对NRT1/PTR FAMILY 8.3基因进行克隆、生物信息学分析,并分析了不同浓度及不同形态氮素以及干旱下该基因表达情况。研究结果:草地早熟禾NRT1/PTR FAMILY 8.3基因包含典型的主要协同转运蛋白超家族(Major facilitator superfamily,MFS)结构域,与二穗短柄草(Brachypodium distachyon)高度同源;荧光定量PCR分析表明,该基因根部、叶部的表达量显著高于茎部;氮浓度为7.5 mM时,不同形态氮素诱导下,NaNO3处理组有利于该基因表达;无氮、高氮组(0,15 mM NaNO3)基因的表达量显著高于适氮组(7.5 mM NaNO3);干旱胁迫可促进其表达。研究结果为探究NRT1/PTR FAMILY 8.3在不同氮素环境中的调节机制,培育氮素利用率高的优质草种提供理论基础。
基金support and help of many individuals in the SASTRA University
文摘In a manufacturing industry, mixed model assembly line(MMAL) is preferred in order to meet the variety in product demand. MMAL balancing helps in assembling products with similar characteristics in a random fashion. The objective of this work aims in reducing the number of workstations, work load index between stations and within each station. As manual contribution of workers in final assembly line is more, ergonomics is taken as an additional objective function. Ergonomic risk level of a workstation is evaluated using a parameter called accumulated risk posture(ARP), which is calculated using rapid upper limb assessment(RULA) check sheet. This work is based on the case study of an MMAL problem in Rane(Madras) Ltd.(India), in which a problem based genetic algorithm(GA) has been proposed to minimize the mentioned objectives. The working of the genetic operators such as selection, crossover and mutation has been modified with respect to the addressed MMAL problem. The results show that there is a significant impact over productivity and the process time of the final assembled product, i.e., the rate of production is increased by 39.5% and the assembly time for one particular model is reduced to 13 min from existing 18 min. Also, the space required using the proposed assembly line is only 200 m2 against existing 350 m2. Further, the algorithm helps in reducing workers fatigue(i.e., ergonomic friendly).
文摘This review article aims to give a comprehensive review of periodic orbits in the circular restricted three-body problem(CRTBP),which is a standard ideal model for the Earth-Moon system and is closest to the practical mechanical model.It focuses the attention on periodic orbits in the Earth-Moon system.This work is primarily motivated by a series of missions and plans that take advantages of the three-body periodic orbits near the libration points or around two gravitational celestial bodies.Firstly,simple periodic orbits and their classification that is usually considered to be early work before 1970 are summarized,and periodic orbits around Lagrange points,either planar or three-dimensional,are intensively studied during past decades.Subsequently,stability index of a periodic orbit and bifurcation analysis are presented,which demonstrate a guideline to find more periodic orbits inspired by bifurcation signals.Then,the practical techniques for computing a wide range of periodic orbits and associated quasi-periodic orbits,as well as constructing database of periodic orbits by numerical searching techniques are also presented.For those unstable periodic orbits,the station keeping maneuvers are reviewed.Finally,the applications of periodic orbits are presented,including those in practical missions,under consideration,and still in conceptual design stage.This review article has the function of bridging between engineers and researchers,so as to make it more convenient and faster for engineers to understand the complex restricted three-body problem(RTBP).At the same time,it can also provide some technical thinking for general researchers.
基金Project(60763001)supported by the National Natural Science Foundation of ChinaProjects(2009GZS0027,2010GZS0072)supported by the Natural Science Foundation of Jiangxi Province,China
文摘In order to overcome defects of the classical hidden Markov model (HMM), Markov family model (MFM), a new statistical model was proposed. Markov family model was applied to speech recognition and natural language processing. The speaker independently continuous speech recognition experiments and the part-of-speech tagging experiments show that Markov family model has higher performance than hidden Markov model. The precision is enhanced from 94.642% to 96.214% in the part-of-speech tagging experiments, and the work rate is reduced by 11.9% in the speech recognition experiments with respect to HMM baseline system.
文摘The Myb family of proteins is a group offunctionally diverse transcriptional activatorsfound in both plants and animals that ischaracterized by a conserved DNA bindingdomain of approximately 50 amino acids.Inplants,Myb proteins are involved in control
基金Supported by Heilongjiang Postdoctoral Fund(LBH-Z12045)Northeast Agricultural University Innovation Foundation For Postgraduate(yjscx14053)
文摘MicroRNA（miRNA） is a class of important regulating non-coding small molecular RNA. The gma-MIR166 gene family consists of 21 members and their expression patterns diversify widely. It is important to analyze the evolution of gma-MIR166 gene family in order to understand the evolutionary mechanisms of miRNAs in soybean. In this study, we implemented soybean wide genome block analysis, the molecular phylogeny of gma-MIR166 and block analysis of gma-MIR166 family. The results showed that both chromosome big segmental duplications and tandem duplications were main reasons contributed to the expanding of gmaMIR166 gene family. These findings suggested that gma-MIR166 gene family might originate from one or two ancient miRNA genes. The results of research provided a support for evolutionary study of miRNAs in soybean and related species in Fabaceae.
文摘The ongoing need for better fuel economy and lower exhaust pollution of vehicles has increased the employment of electric power steering(EPS)in automotives.Optimal design of EPS for a product family reduces the development and fabrication costs significantly.In this paper,the TOPSIS method along with the NSGA-Ⅱis employed to find an optimum family of EPS for an automotive platform.A multi-objective optimization problem is defined considering road feel,steering portability,RMS of Ackerman error,and product family penalty function(PFPF)as the conflicting objective functions.The results for the single objective optimization problems and the ones for the multi-objective optimization problem,as well as two suggested trade-off design points are presented,compared and discussed.For the two suggested points,performance at one objective function is deteriorated by about 1%,while the commonality is increased by 20%–40%,which shows the effectiveness of the proposed method in first finding the non-dominated design points and then selecting the trade-off among the obtained points.The results indicate that the obtained trade-off points have superior performance within the product family with maximum number of common parts.
基金Project(JSPS.KAKENHI22560451) supported by the Japan Society for the Promotion of ScienceProject(69904003) supported by the National Natural Science Foundation of ChinaProject(YJ0267016) supported by the Advanced Ordnance Research Supporting Fund of China
文摘Let P（s, δ） be a sphere plant family described by the transfer function set where the coefficients of the denominator and numerator polynomials are affine in a real uncertain parameter vector δ satisfying the Euclidean norm constraint ｜｜δ｜｜〈δ. The concept of stabilizability radius of P（s, δ） is introduced which is the norm bound δs for δ such that every member plant of P（s, δ） is stabilizable if and only if ｜｜δ｜｜〈δs. The stabilizability radius can be simply interpreted as the ＇largest sphere＇ around the nominal plant P（s,θ） such that P（s, δ） is stabilizable. The numerical method and the analytical method are presented to solve the stabilizability radius calculation problem of the sphere plants.
基金funded by the National Natural Science Foundation of China(31530053/31621005)the National Key R&D Program(2016YFD0101401/2017YFD0101601)
文摘Background:Cotton(Gossypium hirsutum) provides the largest natural fiber for the textile manufacturing industries,but its production is on the decline due to the effects of salinity.Soil salt-alkalization leads to damage in cotton growth and a decrease in yields.Hyperosmolality-gated calcium-permeable channels(OSCA) have been found to be involved in the detection of extracellular changes which trigger an increase in cytosolic free calcium concentration.Hyperosmolality-induced calcium ion increases have been widely speculated to be playing a role in osmosensing in plants.However,the molecular nature of the corresponding calcium ion channels remains unclearly.In this research work,we describe the OSCA genes and their putative function in osmosensing in plants by carrying out genomewide identification,characterization and functional analysis of the significantly up-regulated OSCA gene,GhOSCA1.1 through reverse genetics.Result:A total of 35,21 and 22 OSCA genes were identified in G.hirsutum,G.arboreum,and G.raimondii genomes,respectively,and were classified into four different clades according to their gene structure and phylogenetic relationship.Gene and protein structure analysis indicated that 35 GhOSCA genes contained a conserved RSN17 TM(PF02714) domain.Moreover,the cis-regulatory element analysis indicated that the OSCA genes were involved in response to abiotic stress.Furthermore,the knockdown of one of the highly up-regulated genes,GhOSCA1.1 showed that the virus-induced gene silenced(VIGS) plants were highly sensitive to dehydration and salinity stresses compared with the none VIGS plants as evident with higher concentration levels of oxidant enzymes compared with the antioxidant enzymes on the leaves of the stressed plants.Conclusion:This study provides the first systematic analysis of the OSCA gene family and will be important for understanding the putative functions of the proteins encoded by the OSCA genes in cotton.These results provide a new insight of defense responses in general and lay the foundation for further investigation of the molecular role played by the OSCA genes,thereby providing suitable approaches to improve crop performance under salinity and drought stress conditions.
基金Project(51275362)supported by the National Natural Science Foundation of ChinaProject(2014ZX04015021)supported by National Science and Technology Major Project,China
文摘Product family(PF) is the most important part of product platform. A new method is proposed to mine PF based on multi-space product data in PLM database. Product structure tree(PST) and bill of material(BOM) are used as the data source. A PF can be obtained by mining physics space, logic space and attribute space of product data. In this work, firstly, a PLM database is described, consisting of data organization form, data structure, and data characteristics. Then the PF mining method introduces the sequence alignment techniques used in bio-informatics, which mainly includes data pre-processing, regularization, mining algorithm and cluster analysis. Finally, the feasibility and effectiveness of the proposed method are verified by a case study of high and middle pressure valve, demonstrating a feasible method to obtain PF from PLM database.
文摘This essay studies various family-related factors that influence a child’s academic achievement in school in P.R. China. The factors are illustrated under three categories: the family’s social class and education, early home environment and family material condition. The author discusses the relevant factors by way of relating the knowledge of social environment to his own experiences as a student and then teacher in China. The essay closes with a discussion directing the public’s attention to the concern about home-related factors influencing a child’s academic achievements in school.
