Introduction Regenerative medicine holds great promise for the treatment of diseases that are unbeatable at present,such as various gene and neurological disorders,cardiovascular diseases,as well as hematological mali...Introduction Regenerative medicine holds great promise for the treatment of diseases that are unbeatable at present,such as various gene and neurological disorders,cardiovascular diseases,as well as hematological malignancies.Realization of this potential remains limited by current challenges associated with the control of cell phenotype and function in cell culture.In this respect,the fate of cells is dictated by the in vivo microenvironment where these cells interact with both the extracellular matrix(ECM)and with neighboring cells.The ECM serves as a structural support for cells and provides,in concert with spatio-temporally arranged biochemical cues such as soluble factors,topographical and mechanical cues that direct cell adhesion,spreading,migra-展开更多
Small and medium-sized enterprises have developed rapidly under the guidance and support of the national industrial policy.Because of the influence of the post financial crisis,the rate of the global economy developme...Small and medium-sized enterprises have developed rapidly under the guidance and support of the national industrial policy.Because of the influence of the post financial crisis,the rate of the global economy development decreased and the market competition increased,the profit of small and medium-sized enterprises is on the decline or even in a loss.The paper,based on the value creation logic of Balanced Score Card,put forward that we should,with the Differentiation Strategy as the basis,using Strategy Map and Cascade Strategy,integrate the key internal procedures to increase the strategic preparation of intangible assets to guide the business model innovation of small and medium-sized enterprises and promote the rapid development of small and medium-sized enterprises.展开更多
基金supported by the National Institute of Health(NIH HL83008)
文摘Introduction Regenerative medicine holds great promise for the treatment of diseases that are unbeatable at present,such as various gene and neurological disorders,cardiovascular diseases,as well as hematological malignancies.Realization of this potential remains limited by current challenges associated with the control of cell phenotype and function in cell culture.In this respect,the fate of cells is dictated by the in vivo microenvironment where these cells interact with both the extracellular matrix(ECM)and with neighboring cells.The ECM serves as a structural support for cells and provides,in concert with spatio-temporally arranged biochemical cues such as soluble factors,topographical and mechanical cues that direct cell adhesion,spreading,migra-
基金the phased achievement of the social science research project of Shandong Province:Research on industrial transformation and upgrading of equipment manufacturing industry in Shandong Province(No:13CJJJ02)
文摘Small and medium-sized enterprises have developed rapidly under the guidance and support of the national industrial policy.Because of the influence of the post financial crisis,the rate of the global economy development decreased and the market competition increased,the profit of small and medium-sized enterprises is on the decline or even in a loss.The paper,based on the value creation logic of Balanced Score Card,put forward that we should,with the Differentiation Strategy as the basis,using Strategy Map and Cascade Strategy,integrate the key internal procedures to increase the strategic preparation of intangible assets to guide the business model innovation of small and medium-sized enterprises and promote the rapid development of small and medium-sized enterprises.