期刊文献+
共找到14,881篇文章
< 1 2 250 >
每页显示 20 50 100
ZBED2通过糖酵解代谢诱导肝细胞癌中PD-L1表达促进免疫逃逸的机制研究 被引量:2
1
作者 黄金石 丁亚亭 曹建中 《中国免疫学杂志》 北大核心 2025年第2期367-373,共7页
目的:探讨锌指BED结构域含蛋白2(ZBED2)通过糖酵解通路对肝细胞癌(HCC)免疫逃逸的影响及潜在机制。方法:生物信息学数据库分析ZBED2在HCC组织中的表达情况及二者的结合位点,分析ZBED2调控的通路,以及ZBED2与糖酵解基因的相关性。qPCR和W... 目的:探讨锌指BED结构域含蛋白2(ZBED2)通过糖酵解通路对肝细胞癌(HCC)免疫逃逸的影响及潜在机制。方法:生物信息学数据库分析ZBED2在HCC组织中的表达情况及二者的结合位点,分析ZBED2调控的通路,以及ZBED2与糖酵解基因的相关性。qPCR和Western blot检测ZBED2及程序性细胞死亡配体1(PD-L1)在HCC细胞中的表达,MTT检测细胞活力,细胞毒性实验检测CD8+T细胞毒性,ELISA检测细胞因子表达;细胞外流量分析仪检测胞外酸化率(ECAR)和耗氧率(OCR),qPCR检测糖酵解相关基因表达,试剂盒检测糖酵解指标,免疫组织化学染色检测肿瘤组织中CD8^(+)T细胞表达。结果:ZBED2在HCC中表达上调,过表达ZBED2可促进PD-L1表达,抑制CD8^(+)T细胞对HCC细胞的毒性。过表达ZBED2通过激活糖酵解通路抑制HCC中CD8^(+)T细胞活性,进一步添加糖酵解抑制剂2-脱氧-D-葡萄糖(2-DG)减弱了以上结果。体内实验发现,敲低ZBED2可抑制小鼠肿瘤生长及PD-L1表达,促进体内CD8+T细胞浸润。结论:ZBED2通过糖酵解代谢诱导HCC中PDL1表达,促进免疫逃逸。 展开更多
关键词 锌指bed结构域含蛋白2 糖酵解 肝细胞癌 免疫逃逸
在线阅读 下载PDF
紫菜zf-BED转录因子的鉴定与比较进化分析
2
作者 王若寒 高大海 《海洋与湖沼》 北大核心 2025年第5期1205-1214,共10页
zf-BED(zinc-finger BED)转录因子家族广泛参与调控植物生长发育以及逆境响应,但紫菜(Porphyra sensu lato)中zf-BED的组成和进化模式尚未明确。基于条斑紫菜(Pyropia yezoensis)、坛紫菜(Pyropia haitanensis)和脐形紫菜(Porphyra umbi... zf-BED(zinc-finger BED)转录因子家族广泛参与调控植物生长发育以及逆境响应,但紫菜(Porphyra sensu lato)中zf-BED的组成和进化模式尚未明确。基于条斑紫菜(Pyropia yezoensis)、坛紫菜(Pyropia haitanensis)和脐形紫菜(Porphyra umbilicalis)基因组数据,通过生物信息学方法鉴定到11个条斑紫菜、2个坛紫菜和1个脐形紫菜zf-BED基因。根据其结构域特征分为4个类别:陆地植物中常见的I类(zf-BED_DUFdomain_Dimer_Tnp_hAT)、II类(zf-BED)、IV类(zf-BED_DUFdomain)以及一个包含碳氮水解酶结构域,不同于陆地植物的新类别(zf-BED_C-N_Hydrolase)。基因同源性分析和系统发育分析的结果表明,条斑紫菜zf-BED基因与坛紫菜存在2个直系同源基因,与脐形紫菜存在1个直系同源基因,zf-BED基因在条斑紫菜中发生了特异性扩增。此外,紫菜与陆地植物zf-BED基因聚在一起,形成两个分支,推断其具有古老的起源。基于条斑紫菜和坛紫菜的营养藻丝、壳孢子囊枝及30日龄叶状体的转录组数据,发现zf-BED基因在不同发育阶段的表达模式存在差异。该研究系统分析了紫菜zf-BED的基因构成、系统发育关系和表达特征,揭示了该基因家族在紫菜中的进化特征及功能分化现象,为阐明紫菜zf-BED基因的生物学功能提供一定的理论依据。 展开更多
关键词 条斑紫菜 坛紫菜 脐形紫菜 zf-bed基因家族 生物信息学分析 表达分析
在线阅读 下载PDF
High-temperature stability and mechanical property optimization of laser powder bed fusion 316L steel after controlled annealing
3
作者 LI Wen-qi MENG Li-xin +3 位作者 ZHANG Qian-fen LU Hui-hu NIU Xiao-feng HOU Hua 《Journal of Central South University》 2025年第4期1179-1193,共15页
The research demonstrated that laser powder bed fusion(LPBF)coupled with controlled annealing at 1200°C,could significantly increase the proportion of coincidence site lattice(CSL)grain boundary,thereby achieving... The research demonstrated that laser powder bed fusion(LPBF)coupled with controlled annealing at 1200°C,could significantly increase the proportion of coincidence site lattice(CSL)grain boundary,thereby achieving an outstanding synergy of enhanced strength and exceptional ductility.The plastic deformation behavior,strain hardening behavior,and fracture behavior of LPBF 316L steel annealing at 1200℃for 20 h were studied through quasi-in-situ tensile process.It was found that LPBF 316L steel formed a certain proportion of deformation twins during the tensile process,and the formation of twins changed the crystal orientation,thus promoting further slip and crystal deformation.The synergistic effect of slip and twin promoted higher plasticity.LPBF process coupled with controlled annealing at 1200°C for 20 h leads to a ultimate tensile strength of 613 MPa and total elongation of 73.8%. 展开更多
关键词 laser powder bed fusion heat treatment microstructural evolution mechanical behavior plastic deformation behavior
在线阅读 下载PDF
A cohesion loss model for determining residual strength of deep bedded sandstone
4
作者 SONG Zhi-xiang ZHANG Jun-wen +12 位作者 ZHANG Yu-jie WU Shao-kang BAI Xu-yang ZHANG Li-chao ZHANG Sui-lin ZHANG Xu-wen FAN Guang-chen LI Wen-jun ZENG Ban-quan WANG Shi-ji SUN Xiao-yan SANG Pei-miao LI Ning 《Journal of Central South University》 2025年第7期2593-2618,共26页
Rock residual strength,as an important input parameter,plays an indispensable role in proposing the reasonable and scientific scheme about stope design,underground tunnel excavation and stability evaluation of deep ch... Rock residual strength,as an important input parameter,plays an indispensable role in proposing the reasonable and scientific scheme about stope design,underground tunnel excavation and stability evaluation of deep chambers.Therefore,previous residual strength models of rocks established were reviewed.And corresponding related problems were stated.Subsequently,starting from the effects of bedding and whole life-cycle evolution process,series of triaxial mechanical tests of deep bedded sandstone with five bedding angles were conducted under different confining pressures.Then,six residual strength models considering the effects of bedding and whole life-cycle evolution process were established and evaluated.Finally,a cohesion loss model for determining residual strength of deep bedded sandstone was verified.The results showed that the effects of bedding and whole life-cycle evolution process had both significant influences on the evolution characteristic of residual strength of deep bedded sandstone.Additionally,residual strength parameters:residual cohesion and residual internal friction angle of deep bedded sandstone were not constant,which both significantly changed with increasing bedding angle.Besides,the cohesion loss model was the most suitable for determining and estimating the residual strength of bedded rocks,which could provide more accurate theoretical guidance for the stability control of deep chambers. 展开更多
关键词 residual strength deep bedded sandstone whole life-cycle evolution process cohesion loss model rock mechanics
在线阅读 下载PDF
Seismic pseudo-static stability analysis of bedding jointed rock slope stability under the interaction of the upper dangerous rock mass and lower stepped slope mass based on acceleration assessment
5
作者 LI De-jian XIAO Yu +3 位作者 YANG Yan-song YU Peng-cheng ZHANG Ying-bin ZHAO Lian-heng 《Journal of Central South University》 2025年第7期2619-2637,共19页
In the practical slope engineering,the stability of lower sliding mass(region A)with back tensile cracks of the jointed rock slope attracts more attentions,but the upper rock mass(region B)may also be unstable.Therefo... In the practical slope engineering,the stability of lower sliding mass(region A)with back tensile cracks of the jointed rock slope attracts more attentions,but the upper rock mass(region B)may also be unstable.Therefore,in this study,based on the stepped failure mode of bedding jointed rock slopes,considering the influence of the upper rock mass on the lower stepped sliding mass,the improved failure model for analyzing the interaction force(F_(AB))between two regions is constructed,and the safety factors(F_(S))of two regions and whole region are derived.In addition,this paper proposes a method to determine the existence of F_(AB) using their respective acceleration values(a_(A) and a_(B))when regions A and B are unstable.The influences of key parameters on two regions and the whole region are analyzed.The results show that the variation of the F_(AB) and F_(S) of two regions can be obtained accurately based on the improved failure model.The accuracy of the improved failure model is verified by comparative analysis.The research results can explain the interaction mechanism of two regions and the natural phenomenon of slope failure caused by the development of cracks. 展开更多
关键词 bedding jointed rock slope upper dangerous rock mass stepped sliding interaction mechanism stability analysis
在线阅读 下载PDF
Effect of process parameters on microstructure and mechanical properties of a nickel-aluminum-bronze alloy fabricated by laser powder bed fusion 被引量:1
6
作者 HAN Chang-jun ZOU Yu-jin +7 位作者 HU Gao-ling DONG Zhi LI Kai HUANG Jin-miao LI Bo-yuan ZHOU Kun YANG Yong-qiang WANG Di 《Journal of Central South University》 SCIE EI CAS CSCD 2024年第8期2944-2960,共17页
This work investigated the effect of process parameters on densification,microstructure,and mechanical properties of a nickel-aluminum-bronze(NAB)alloy fabricated by laser powder bed fusion(LPBF)additive manufacturing... This work investigated the effect of process parameters on densification,microstructure,and mechanical properties of a nickel-aluminum-bronze(NAB)alloy fabricated by laser powder bed fusion(LPBF)additive manufacturing.The LPBF-printed NAB alloy samples with relative densities of over 98.5%were obtained under the volumetric energy density range of 200−250 J/mm^(3).The microstructure of the NAB alloy printed in both horizontal and vertical planes primarily consisted ofβ'martensitic phase and bandedαphase.In particular,a coarser-columnar grain structure and stronger crystallographic texture were achieved in the vertical plane,where the maximum texture intensity was 30.56 times greater than that of random textures at the(100)plane.Increasing the volumetric energy density resulted in a decrease in the columnar grain size,while increasing the amount ofαphase.Notably,β_(1)'martensitic structures with nanotwins and nanoscaleκ-phase precipitates were identified in the microstructure of LPBF-printed NAB samples with a volumetric energy density of 250 J/mm^(3).Furthermore,under optimal process parameters with a laser power of 350 W and scanning speed of 800 mm/s,significant improvements were observed in the microhardness(HV 386)and ultimate tensile strength(671 MPa),which was attributed to an increase in refined acicular martensite. 展开更多
关键词 copper alloy nickel-aluminum-bronze alloy laser powder bed fusion additive manufacturing
在线阅读 下载PDF
Characterization of a Powertrain Test Bed in the Context of Virtual Validation of Drivability
7
作者 Schmidt HENRIK Prokop GÜNTHER 《同济大学学报(自然科学版)》 EI CAS CSCD 北大核心 2024年第S01期9-19,共11页
Technological trends in the automotive industry toward a software-defined and autonomous vehicle require a reassessment of today’s vehicle development process.The validation process soaringly shapes after starting wi... Technological trends in the automotive industry toward a software-defined and autonomous vehicle require a reassessment of today’s vehicle development process.The validation process soaringly shapes after starting with hardware-in-the-loop testing of control units and reproducing real-world maneuvers and physical interaction chains.Here,the road-to-rig approach offers a vast potential to reduce validation time and costs significantly.The present research study investigates the maneuver reproduction of drivability phenomena at a powertrain test bed.Although drivability phenomena occur in the frequency range of most up to 30∙Hz,the design and characteristics substantially impact the test setup’s validity.By utilization of modal analysis,the influence of the test bed on the mechanical characteristic is shown.Furthermore,the sensitivity of the natural modes of each component,from either specimen or test bed site,is determined.In contrast,the uncertainty of the deployed measurement equipment also affects the validity.Instead of an accuracy class indication,we apply the ISO/IEC Guide 98 to the measurement equipment and the test bed setup to increase the fidelity of the validation task.In conclusion,the present paper contributes to a traceable validity determination of the road-to-rig approach by providing objective metrics and methods. 展开更多
关键词 powertrain test bed virtual validation modal analysis powertrain-hardware-in-the-loop DRIVABILITY measurement uncertainty
在线阅读 下载PDF
应用BED-CEIA方法估算江苏省男男性行为人群艾滋病病毒感染的新发感染率 被引量:23
8
作者 胡海洋 沈圣 +3 位作者 还锡萍 闫红静 肖瑶 蒋岩 《南京医科大学学报(自然科学版)》 CAS CSCD 北大核心 2010年第4期467-471,共5页
目的:了解江苏省男男性行为人群(MSM)艾滋病病毒(HIV)的感染状况,估算HIV在该人群中的新发感染率。方法:对2008年国家男男性行为人群艾滋病综合防治试点工作的710份样本,进行HIV-1初筛、复检及确证试验,检出的HIV-1阳性样本,再应用BEDHI... 目的:了解江苏省男男性行为人群(MSM)艾滋病病毒(HIV)的感染状况,估算HIV在该人群中的新发感染率。方法:对2008年国家男男性行为人群艾滋病综合防治试点工作的710份样本,进行HIV-1初筛、复检及确证试验,检出的HIV-1阳性样本,再应用BEDHIV-1IgG捕获酶免疫法(BED-CEIA)检出其中的新发感染样本,进而估算该人群的HIV-1新发感染率。结果:710份样本共检出HIV-1阳性样本40份,HIV-1感染率为5.63%;40份HIV-1阳性样本中的23份被判定为新发感染,感染者中新发感染的比例高达57.5%;校正后的HIV-1新发感染率为7.54%(95%CI:4.46%~10.62%)。结论:HIV-1在江苏省MSM人群中的流行已经处于较高水平且新发感染状况不容乐观,必须加大防控力度。 展开更多
关键词 艾滋病病毒 bed—CEIA 新发感染率 男男性行为人群
在线阅读 下载PDF
BED混合燃料稳定性及对高原地区发动机性能影响的研究 被引量:17
9
作者 刘少华 申立中 +2 位作者 张生斌 毕玉华 雷基林 《汽车工程》 EI CSCD 北大核心 2012年第9期816-820,共5页
为研究生物柴油-乙醇-柴油(简称BED)混合燃料对高原地区发动机的性能影响,在不同环境下进行了BED混合燃料的相溶性和稳定性测试的基础上,在高原环境下进行了高压共轨柴油机燃用纯柴油和6组不同比例BED混合燃料的台架试验。结果表明,生... 为研究生物柴油-乙醇-柴油(简称BED)混合燃料对高原地区发动机的性能影响,在不同环境下进行了BED混合燃料的相溶性和稳定性测试的基础上,在高原环境下进行了高压共轨柴油机燃用纯柴油和6组不同比例BED混合燃料的台架试验。结果表明,生物柴油、乙醇和柴油可在一定温度范围内按照不同比例配制成稳定的混合燃料,但其稳定性随温度降低而变差。当喷入气缸内燃料体积不变时,与燃用纯柴油相比,燃用BED混合燃料发动机的动力性下降;经济性有所改善,高速时改善效果更为明显;碳烟排放下降,高负荷时比低负荷时下降幅度更大。BED混合燃料的最佳喷油提前角随生物柴油比例的增加而减小,随乙醇比例的增加而增大。 展开更多
关键词 bed混合燃料 高原地区 稳定性 高压共轨柴油机 台架试验
在线阅读 下载PDF
“BED”信用评估方法 被引量:6
10
作者 赵振全 周佰成 赵云立 《中国软科学》 CSSCI 北大核心 2003年第11期154-160,共7页
本文根据中国工业企业的实际情况创新性地给出了新的信用评估体系(简称BED评估体系),该评估体系为10个等级64种评级结果,在定性分析方面与国际上的十等级制度接轨,同时具备在同一等级下的风险特征刻画;在定量分析方面又为企业的信用积... 本文根据中国工业企业的实际情况创新性地给出了新的信用评估体系(简称BED评估体系),该评估体系为10个等级64种评级结果,在定性分析方面与国际上的十等级制度接轨,同时具备在同一等级下的风险特征刻画;在定量分析方面又为企业的信用积分做了定量描述。该评估体系中的指标选择上我们根据中国特色进行了取舍,各个指标的权重采用层次分析法来确定。 展开更多
关键词 信用评估 指标体系 层次分析法 bed评估体系 工业企业
在线阅读 下载PDF
南极冰盖地形数据库BEDMAP 2述评 被引量:6
11
作者 陈昀 孙波 +2 位作者 刘春 崔祥斌 王甜甜 《极地研究》 CAS CSCD 北大核心 2014年第2期254-261,共8页
南极冰盖物质收支与不稳定性对全球气候变化和海平面升高有着重要影响,而冰盖厚度和冰下地形则是研究南极冰盖的物质平衡、动力及不稳定性极为重要的参数。自20世纪50年代以来,国际上针对南极冰盖开展了大量的冰雷达以及重、磁测量,这... 南极冰盖物质收支与不稳定性对全球气候变化和海平面升高有着重要影响,而冰盖厚度和冰下地形则是研究南极冰盖的物质平衡、动力及不稳定性极为重要的参数。自20世纪50年代以来,国际上针对南极冰盖开展了大量的冰雷达以及重、磁测量,这些测量结果被汇集并形成冰厚和冰下地形数据库,进而服务于冰盖模式和地球系统研究,最新推出的成果便是BEDMAP 2(Bedrock Mapping Project 2)。首先介绍了BEDMAP 2的数据来源、结构以及数据处理,并讨论了数据的质量评价,然后分析了BEDMAP 2中展示的整个南极冰盖与冰下地形及其特点。最后,对于BEDMAP 2对中国在南极冰盖考察和研究方面的作用进行了一些讨论与展望。 展开更多
关键词 南极冰盖 bedMAP 2 表面高程 冰厚 冰下地形
在线阅读 下载PDF
一类带Bedding反应函数的捕食模型在不同斑块环境中的扩散作用 被引量:1
12
作者 武海辉 窦霁虹 王秋芬 《陕西科技大学学报(自然科学版)》 2009年第5期139-144,共6页
研究了一类带Bedding类反应函数的捕食与被捕食扩散模型的整体及局部性态,证明了该模型在第一象限内存在一个吸引域,且它的一切正解是强持续生存的;得出系统的正平衡点是局部渐近稳定的充分条件;最后通过数值模拟仿真进一步验证了定理... 研究了一类带Bedding类反应函数的捕食与被捕食扩散模型的整体及局部性态,证明了该模型在第一象限内存在一个吸引域,且它的一切正解是强持续生存的;得出系统的正平衡点是局部渐近稳定的充分条件;最后通过数值模拟仿真进一步验证了定理的准确性,补充和完善了前人的结果. 展开更多
关键词 强持续生存 bedding反应函数 扩散率
在线阅读 下载PDF
The Effect of Grain Properties for Artificial Bedload Supply
13
作者 Markus PROMNY 《四川大学学报(工程科学版)》 EI CAS CSCD 北大核心 2005年第S1期30-33,共4页
The German Armed Forces University in Munich has conducted experiments in a laboratory flume to determine the influence of roundness on bed load transport.The investigations were assigned by the German Federal Institu... The German Armed Forces University in Munich has conducted experiments in a laboratory flume to determine the influence of roundness on bed load transport.The investigations were assigned by the German Federal Institute of Hydrology (BIG),with a focus on incipient motion,transport velocity and the depth of mixing into the riverbed. The results of the experiments show that the transport velocity of angular graim is lower and the critical shear stress for incipient motion is slightly higher than of well-ro... 展开更多
关键词 bed load supply bed load transport grain properties ROUNDNESS tracer experiments incipient motion transport velocity
在线阅读 下载PDF
Mechanism Study of Lateral Bed Pressure Wave of Large Scale CFB Boilers
14
作者 HU Nan LI Jinjing +2 位作者 LIU Xuemin YANG Hairui LV Junfu 《中国电机工程学报》 EI CSCD 北大核心 2013年第20期I0001-I0016,共16页
When large-scale circulating fluidized bed(CFB)boilers are working under a 1ow load condition.severe bed pressure swing often occurs and poses a serious threat to boiler stability and safety.Up to now,there are not en... When large-scale circulating fluidized bed(CFB)boilers are working under a 1ow load condition.severe bed pressure swing often occurs and poses a serious threat to boiler stability and safety.Up to now,there are not enough theoretical studies on the bed pressure swing phenomenon. 展开更多
关键词 large—scale circulating fluidized bed(CFB)boiler bed pressure swing RESONANCE fluidization reconstruction
在线阅读 下载PDF
Zbed6基因敲除对小鼠骨骼肌生长发育的影响及其分子作用机制研究 被引量:2
15
作者 刘铃 王圣楠 +3 位作者 王丹丹 马月辉 蒋琳 崔凯 《中国畜牧兽医》 CAS CSCD 北大核心 2023年第9期3641-3651,共11页
【目的】研究锌指BED结构域包含蛋白6(ZBED6)基因敲除对青春期小鼠骨骼肌生长发育的影响及其分子作用机制。【方法】以8周龄野生型(WT)和Zbed6基因敲除(Zbed6^(-/-))C57BL/6小鼠为试验对象,采集血液,用ELISA法检测血清睾酮含量;分离骨... 【目的】研究锌指BED结构域包含蛋白6(ZBED6)基因敲除对青春期小鼠骨骼肌生长发育的影响及其分子作用机制。【方法】以8周龄野生型(WT)和Zbed6基因敲除(Zbed6^(-/-))C57BL/6小鼠为试验对象,采集血液,用ELISA法检测血清睾酮含量;分离骨骼肌组织并记录肌肉重、肌肉率。通过骨骼肌组织切片和免疫组化分析检测骨骼肌肌纤维面积及IGF2蛋白表达水平。通过Illumina NovaseqTM6000高通量测序对WT和Zbed6^(-/-)雌、雄小鼠进行转录组测序分析,联合小鼠ZBED6靶基因数据,筛选在Zbed6基因敲除小鼠肌肉组织中发挥作用的下游靶基因,并通过实时荧光定量PCR验证转录组测序结果中差异表达基因的可靠性。【结果】与WT小鼠相比,Zbed6^(-/-)雌、雄小鼠肌肉重、肌肉率均极显著增加(P<0.01)。Zbed6基因敲除后,雌、雄小鼠骨骼肌Zbed6基因mRNA表达量显著降低(P<0.05),IGF2的mRNA及蛋白表达量均显著或极显著增加(P<0.05;P<0.01),血清睾酮含量极显著升高(P<0.01)。转录组测序结果显示,Zbed6^(-/-)组雄鼠骨骼肌中共筛选到38个差异表达基因,其中22个上调,16个基因下调;雌鼠骨骼肌中筛选到49个差异表达基因,其中19个基因上调,30个基因下调。共有10个差异表达基因在雌、雄小鼠中共同表达,其中Dock3、Lhx2、Brsk2、Caskin1、Gbe1为ZBED6靶基因。实时荧光定量PCR检测发现,4个差异表达基因的表达情况与转录组测序分析结果一致,证实测序结果准确可信。【结论】Zbed6^(-/-)促进青春期小鼠骨骼肌生长发育,增加血清睾酮含量,筛选出Dock3、Lhx2、Brsk2、Caskin1、Gbe1 5个ZBED6靶基因。研究结果为深入探究ZBED6功能提供了新的基因靶点和研究方向,有助于完善ZBED6功能图谱,为大动物品种改良和畜禽瘦肉性状遗传育种研究提供了重要的理论依据。 展开更多
关键词 锌指bed结构域包含蛋白6 骨骼肌 生长发育 转录组测序
在线阅读 下载PDF
瞬变电磁BEDS-FDTD三维正演新算法及稳定性验证 被引量:2
16
作者 柳尚斌 孙怀凤 +2 位作者 李文翰 王震 杨洋 《地球物理学报》 SCIE EI CAS CSCD 北大核心 2023年第2期841-853,共13页
常规FDTD的时间步长需满足Courant-Friedrich-Lewy(CFL)稳定性条件,导致时间迭代步过多,正演非常耗时.针对上述问题,本文采用Backward Euler(BE)差分方法近似Maxwell方程组中场对时间的一阶导数,使时间步长突破CFL限制;引入Direct Split... 常规FDTD的时间步长需满足Courant-Friedrich-Lewy(CFL)稳定性条件,导致时间迭代步过多,正演非常耗时.针对上述问题,本文采用Backward Euler(BE)差分方法近似Maxwell方程组中场对时间的一阶导数,使时间步长突破CFL限制;引入Direct Splitting(DS)策略将电磁场分量解耦,并将大型稀疏矩阵降阶和重构为一系列低阶且主对角占优的三对角矩阵,加快方程求解效率;而且,为了减少模型尺寸,针对上述改进的全新方程,本文采用双线性变换方法(bilinear transform, BT)推导了复频率偏移完全匹配层(complex frequency shifted perfectly matched layer, CFS-PML)吸收边界,形成瞬变电磁三维正演全新算法:BEDS-FDTD.首先采用von Neumann方法测试了新算法在有耗介质中、非均匀时间步长下的稳定性.之后,将BEDS-FDTD算法用于模型实验,并将模拟结果与层状模型的半解析解进行了对比,实验结果证明了新算法的计算精度能够满足需要;同时对新算法的计算效率进行了分析,当采用Tesla A100 GPU计算时,50×50×50网格数目的模型仅用10 s,即使网格数目增加到200×200×200,也仅需224 s.最后,将BEDS-FDTD算法用于复杂三维模型计算. 展开更多
关键词 瞬变电磁 三维正演 bedS CFS-PML 无条件稳定性
在线阅读 下载PDF
Chemical-looping gasification of biomass in a 10 kW_(th) interconnected fluidized bed reactor using Fe_2O_3/Al_2O_3 oxygen carrier 被引量:9
17
作者 HUSEYIN Sozen WEI Guo-qiang +2 位作者 LI Hai-bin HE Fang HUANG Zhen 《燃料化学学报》 EI CAS CSCD 北大核心 2014年第8期922-931,共10页
Abstract:The aim of this research is to design and operate a 10 kW hot chemical-looping gasification(CLG)unit using Fe2O3/Al2O3as an oxygen carrier and saw dust as a fuel.The effect of the operation temperature on gas... Abstract:The aim of this research is to design and operate a 10 kW hot chemical-looping gasification(CLG)unit using Fe2O3/Al2O3as an oxygen carrier and saw dust as a fuel.The effect of the operation temperature on gas composition in the air reactor and the fuel reactor,and the carbon conversion of biomass to CO2and CO in the fuel reactor have been experimentally studied.A total60 h run has been obtained with the same batch of oxygen carrier of iron oxide supported with alumina.The results show that CO and H2concentrations are increased with increasing temperature in the fuel reactor.It is also found that with increasing fuel reactor temperature,both the amount of residual char in the fuel reactor and CO2concentration of the exit gas from the air reactor are degreased.Carbon conversion rate and gasification efficiency are increased by increasing temperature and H2production at 870℃reaches the highest rate.Scanning electron microscopy(SEM),X-ray diffraction(XRD)and BET-surface area tests have been used to characterize fresh and reacted oxygen carrier particles.The results display that the oxygen carrier activity is not declined and the specific surface area of the oxygen carrier particles is not decreased significantly. 展开更多
关键词 chemical-looping gasification hot model BIOMASS Fe2O3/Al2O3 dual circulating fluidized bed
在线阅读 下载PDF
Discrete element method of improved performance of railway ballast bed using elastic sleeper 被引量:10
18
作者 高亮 罗奇 +2 位作者 徐旸 井国庆 蒋函珂 《Journal of Central South University》 SCIE EI CAS CSCD 2015年第8期3223-3231,共9页
With the development of high-speed and heavy-haul railway in China, problems like insufficient thickness of ballast bed and overlarge track stiffness are obvious. Ballast may break into small particles and their conta... With the development of high-speed and heavy-haul railway in China, problems like insufficient thickness of ballast bed and overlarge track stiffness are obvious. Ballast may break into small particles and their contact status will deteriorate under cyclic loading, resulting in ballast degradation. Discrete element method(DEM) was used to research improved performance of ballast bed using elastic sleeper. Clusters were generated by bonding spheres to model real ballasts, while broken bonds were utilized to distinguish breakage. Two kinds of ballast beds with elastic sleeper and conventional sleeper were established, respectively. After applying cyclic loading to the models, differences of mechanical properties between two models were analyzed by contrasting their dynamic behavior indexes, such as particle contact force, sleeper settlement, vibration velocity and acceleration, breakage characteristic. The results illustrate that compared with conventional sleeper, elastic sleeper increases sleeper settlement, while reduces ballast vibration and contact force between particles, which could depress ballast breakage. 展开更多
关键词 railway ballast bed discrete element method elastic sleeper BREAKAGE mechanical property
在线阅读 下载PDF
Modularized dry coal beneficiation technique based on gas-solid fluidized bed 被引量:7
19
作者 赵跃民 李功民 +4 位作者 骆振福 梁春成 唐利刚 陈增强 邢洪波 《Journal of Central South University》 SCIE EI CAS 2011年第2期374-380,共7页
A 40-60 t/h modularized dry coal beneficiation process with a novel method to control the bed was designed around a gas-solid fluidized bed separator. Furthermore, the hydrodynamics of medium-solids consisting of wide... A 40-60 t/h modularized dry coal beneficiation process with a novel method to control the bed was designed around a gas-solid fluidized bed separator. Furthermore, the hydrodynamics of medium-solids consisting of wide-size-range magnetite powder (0.3-0.06 ram) and 〈1 mm fine coal were numerically studied. The simulation results show that the fluidization performance of the wide-size-range medium-solid bed is good. The separation performance of the modularized system was then investigated in detail using a mixture of 〈0.3 mm magnetite powder (mass fraction of 0.3-0.06 mm particles is 91.38 %) and 〈1 mm fine coal as solid media. The experimental results show that at separation densities of 1.33 g/cm^3 or 1.61 g/cm^3, 50-6 mm coal can be separated effectively with probable error, E, values of 0.05 g/cm^3 and 0.06 g/cm^3, respectively. This technique is beneficial for saving water resources and for the clean utilization of coal. 展开更多
关键词 dry coal beneficiation MODULARIZATION gas-solid fluidized bed wide-size-range medium-solids
在线阅读 下载PDF
Strength and thermal behavior of low weight foam geopolymer using circulating fluidized bed combustion fly ash 被引量:7
20
作者 刘泽 邵宁宁 +3 位作者 秦俊峰 孔凡龙 王春雪 王栋民 《Journal of Central South University》 SCIE EI CAS CSCD 2015年第9期3633-3640,共8页
A comparative study of the influence of elevated temperature on foam geopolymer using circulating fluidized bed combustion fly ash(CFA) was reported. Foam geopoymers were prepared with different amounts of foam agen... A comparative study of the influence of elevated temperature on foam geopolymer using circulating fluidized bed combustion fly ash(CFA) was reported. Foam geopoymers were prepared with different amounts of foam agent and different Si O2/Al2O3 molar ratios of 3.1, 3.4, and 3.8. The mechanical, thermo-physical properties and microstructure of the foam geopolymers before and after exposure to elevated temperature of 800, 1000, and 1200 ℃ were investigated. The specimen with Si O2/Al2O3 molar ratio of 3.8 exhibits the highest compressive strength, better microstructure and dimension stability before and after firing. Carnegeite, nepheline, and zeolite crystalline phases appearing after exposure may contribute to the good post-exposure strength. Low weight foam geopolymer using CFA can increase strength and maintain higher stability as high as 1000 ℃. 展开更多
关键词 foam geopolymer circulating fluidized bed combustion fly ash thermal analysis MICROSTRUCTURE STRENGTH
在线阅读 下载PDF
上一页 1 2 250 下一页 到第
使用帮助 返回顶部