Blasting operations,which are crucial to open-pit mine production due to their simplicity and efficiency,require precise control through accurate vibration velocity calculations.The conventional Sadowski formula mainl...Blasting operations,which are crucial to open-pit mine production due to their simplicity and efficiency,require precise control through accurate vibration velocity calculations.The conventional Sadowski formula mainly focuses on blast center distance but neglects the amplification effect of blasting vibration waves by terraced terrain,from which the calculated blasting vibration velocities are smaller than the actual values,affecting the safety of the project.To address this issue,our model introduces the influences of slope and time into Sadowski formula to measure safety through blast vibration displacement.In the northern section of the open-pit quartz mine in Jinchang City,Gansu Province,China,the data of a continuous blasting slope project are referred to.Our findings reveal a noticeable vibration amplification effect during blasting when a multi-stage slope platform undergoes a sudden cross-sectional change near the upper overhanging surface.The amplification vibration coefficient increases with height,while vibration waves within rocks decrease from bottom to top.Conversely,platforms without distinct crosssectional changes exhibit no pronounced amplification during blasting.In addition,the vibration intensity decreases with distance as the rock height difference change propagates.The results obtained by the proposed blast vibration displacement equation incorporating slope shape influence closely agree with real-world scenarios.According to Pearson correlation coefficient(PPMCC)analysis,the average accuracy rate of our model is 88.84%,which exceeds the conventional Sadowski formula(46.92%).展开更多
Quantum states are essential resource for quantum-enhanced applications.Loss incurred in the distribution channel,however,dissipates the high signal-to-noise ratio advantage enjoyed by the squeezed state.Here,we first...Quantum states are essential resource for quantum-enhanced applications.Loss incurred in the distribution channel,however,dissipates the high signal-to-noise ratio advantage enjoyed by the squeezed state.Here,we first demonstrate noise immunity enhancement by using phase-sensitive amplifier(PSA)with measurement-based noiseless linear amplifier(MB-NLA).We explore the signal transfer capability with the amplifier in a noisy channel.The MB-NLA enhanced PSA has obvious suppression effect on channel noises,especially it has improvement for the noise contaminated signal.Better performance can be achieved by flexibly adjusting amplifier parameters.With the amplifier,it is promising to overcome the entanglement-distribution loss and show its superiority in squeezing based quantum sensing.展开更多
Post-processing is indispensable in quantum key distribution （QKD）, which is aimed at sharing secret keys between two distant parties. It mainly consists of key reconciliation and privacy amplification, which is use...Post-processing is indispensable in quantum key distribution （QKD）, which is aimed at sharing secret keys between two distant parties. It mainly consists of key reconciliation and privacy amplification, which is used for sharing the same keys and for distilling unconditional secret keys. In this paper, we focus on speeding up the privacy amplification process by choosing a simple multiplicative universal class of hash functions. By constructing an optimal multiplication algorithm based on four basic multiplication algorithms, we give a fast software implementation of length-adaptive privacy amplification. ＂Length-adaptive＂ indicates that the implementation of privacy amplification automatically adapts to different lengths of input blocks. When the lengths of the input blocks are 1 Mbit and 10 Mbit, the speed of privacy amplification can be as fast as 14.86 Mbps and 10.88 Mbps, respectively. Thus, it is practical for GHz or even higher repetition frequency QKD systems.展开更多
A novel coronavirus of zoonotic origin(SARSCoV-2)has recently been recognized in patients with acute respiratory disease.COVID-19 causative agent is structurally and genetically similar to SARS and bat SARS-like coron...A novel coronavirus of zoonotic origin(SARSCoV-2)has recently been recognized in patients with acute respiratory disease.COVID-19 causative agent is structurally and genetically similar to SARS and bat SARS-like coronaviruses.The drastic increase in the number of coronavirus and its genome sequence have given us an unprecedented opportunity to perform bioinformatics and genomics analysis on this class of viruses.Clinical tests like PCR and ELISA for rapid detection of this virus are urgently needed for early identification of infected patients.However,these techniques are expensive and not readily available for point-of-care(POC)applications.Currently,lack of any rapid,available,and reliable POC detection method gives rise to the progression of COVID-19 as a horrible global problem.To solve the negative features of clinical investigation,we provide a brief introduction of the general features of coronaviruses and describe various amplification assays,sensing,biosensing,immunosensing,and aptasensing for the determination of various groups of coronaviruses applied as a template for the detection of SARS-CoV-2.All sensing and biosensing techniques developed for the determination of various classes of coronaviruses are useful to recognize the newly immerged coronavirus,i.e.,SARS-CoV-2.Also,the introduction of sensing and biosensing methods sheds light on the way of designing a proper screening system to detect the virus at the early stage of infection to tranquilize the speed and vastity of spreading.Among other approaches investigated among molecular approaches and PCR or recognition of viral diseases,LAMP-based methods and LFAs are of great importance for their numerous benefits,which can be helpful to design a universal platform for detection of future emerging pathogenic viruses.展开更多
In order to study the altered molecular events during laryngeal carcinogenesis and elucidate the role of Haras oncogene amplification and mutation. we have examined their profile by polymerase chain reaction (PCR) and...In order to study the altered molecular events during laryngeal carcinogenesis and elucidate the role of Haras oncogene amplification and mutation. we have examined their profile by polymerase chain reaction (PCR) and selective oligonucleotide hybridization. We analyzed the mutational status of codon 12 of Haras in 22 laryngeal carcinomas and 10 normal tissues. and found that 7 of 22 laryngeal carcinomas contained a Ha-ras mutation at codon 12. The frequency of mutation was 32%. None of the normal tissues revealed mutation. Moreover. no amplification was found in cancers when compared to the normal. Ourfindings indicated that the activated Ha-ras gene existed in laryngeal carcinoma. and activation of the Haras gene by mutation at codon 12 might play a key role in laryngeal carcinogenesis.展开更多
FinFET technologies are becoming the mainstream process as technology scales down. Based on a 28-nm bulk p- FinFET device, we have investigated the fin width and height dependence of bipolar amplification for heavy-io...FinFET technologies are becoming the mainstream process as technology scales down. Based on a 28-nm bulk p- FinFET device, we have investigated the fin width and height dependence of bipolar amplification for heavy-ion-irradiated FinFETs by 3D TCAD numerical simulation. Simulation results show that due to a well bipolar conduction mechanism rather than a channel （fin） conduction path, the transistors with narrower fins exhibit a diminished bipolar amplification effect, while the fin height presents a trivial effect on the bipolar amplification and charge collection. The results also indicate that the single event transient （SET） pulse width can be mitigated about 35% at least by optimizing the ratio of fin width and height, which can provide guidance for radiation-hardened applications in bulk FinFET technology.展开更多
Using three-dimensional technology computer-aided design （TCAD） simulation, parasitic bipolar amplification in a single event transient （SET） current of a single transistor and its temperature dependence are studi...Using three-dimensional technology computer-aided design （TCAD） simulation, parasitic bipolar amplification in a single event transient （SET） current of a single transistor and its temperature dependence are studied. We quantify the contributions of different current components in a SET current pulse, and it is found that the proportion of parasitic bipolar amplification in total collected charge is about 30% in both ]30-nm and 90-nm technologies. The temperature dependence of parasitic bipolar amplification and the mechanism of the SET pulse are also investigated and quantified. The results show that the proportion of charge induced by parasitic bipolar increases with rising temperature, which illustrates that the parasitic bipolar amplification plays an important role in the charge collection of a single transistor.展开更多
The rapid and accurate detection of peanuts and soybeans allergen is important to the food safety. In this study, Cu-TCPP nanosheet, a kind of ultra-thin metal-organic framework(MOF)was synthesized and applied in loop...The rapid and accurate detection of peanuts and soybeans allergen is important to the food safety. In this study, Cu-TCPP nanosheet, a kind of ultra-thin metal-organic framework(MOF)was synthesized and applied in loop-mediated isothermal amplification(named Cu-TCPP@LAMP), which can inhibit the non-specific amplification by absorbing and precise temperature releasing of single primer. As thus, Cu-TCPP@LAMP can achieve high sensitivity and specific amplification of the target gene. As a result, peanut and soybean allergens genes contained in food were successfully detected with a favorable detection sensitivity(5 ng/μL for peanuts and 10 ng/μL for soybeans)and reliable repeatability(The coefficient of variation was 3.38% for peanuts and 3.33% for soybeans). Moreover, the established method was utilized for detection of several commercial products, and had a high consistency with the standard method. Apart from food allergens, this novel assay can be widely used in other areas, such as pathogen detection, tumor nucleic acid detection and so on.展开更多
The sense of mammalian hearing exhibits nonlinear phenomena which are most significant to hearing function, such as nonlinear dynamic compression, nonlinear tuning and combination tones. These nonlinear phenomena are ...The sense of mammalian hearing exhibits nonlinear phenomena which are most significant to hearing function, such as nonlinear dynamic compression, nonlinear tuning and combination tones. These nonlinear phenomena are suggested to originate from the Hopf amplification within the cochlea, while the mechanism underlying the Hopf amplification remains elusive. According to the experimental results of force-gating channel operation in hair cells, through a theoretic model, this work reveals a velocity-dependent open probability of force-gating channels in auditory hair cells, and a velocity-dependent active force produced by the force-gating channel operating, which makes sensors hear typical Hopf vibrators with nonlinear hearing phenomena.展开更多
Piezoelectric friction-inertial motor is known for its promise for a long-range and high-resolution motion.The movement of the slider/rotor of the motor is achieved by stick-slip effect.We report a relaxor-based-ferro...Piezoelectric friction-inertial motor is known for its promise for a long-range and high-resolution motion.The movement of the slider/rotor of the motor is achieved by stick-slip effect.We report a relaxor-based-ferroelectric-single-crystal cymbal actuator and a miniature piezoelectric friction-inertial linear motor(abbreviated as PFILM)fabricated with the cymbal actuator.The cymbal actuator is fabricated with a 10 mm diameter disk of 0.70Pb(Mg_(1/3)Nb_(2/3))O_3-0.30PbTiO_3 single crystal.The displacement of the cymbal actuator increases almost proportionally from 0to 23μm with driving voltage up to 500 V,and the minimal hysteresis is observed.The cymbalPFILM with 20 mm motion range works under driving voltage frequency of ca.100 Hz to ca.5kHz,the fastest speed is obtained with 3.5kHz and the no-load speed is 14mm/s and the maximum thrust force is 98 mN.Compared with a PFILM based on multilayer piezoelectric ceramic,the proposed motor has a larger stroke under DC/quasistatic input voltage in fine motion mode,but a smaller driving force in long-travel mode due to lower resonance frequency.展开更多
Single-photon entanglement(SPE) is an important source in quantum communication. In this paper, we put forward a single-photon-assisted noiseless linear amplification protocol to protect the SPE of an arbitrary polari...Single-photon entanglement(SPE) is an important source in quantum communication. In this paper, we put forward a single-photon-assisted noiseless linear amplification protocol to protect the SPE of an arbitrary polarization–time-bin qudit from the photon transmission loss caused by the practical channel noise. After the amplification, the fidelity of the SPE can be effectively increased. Meanwhile, the encoded polarization–time-bin features of the qudit can be well preserved. The protocol can be realized under the current experimental conditions. Moreover, the amplification protocol can be extended to resist complete photon loss and partial photon loss during the photon transmission. After the amplification, we can not only increase the fidelity of the target state, but also solve the decoherence problem simultaneously. Based on the above features, our amplification protocol may be useful in future quantum communication.展开更多
A novel high-birefringence photonic crystal fiber （HB-PCF） with two zero-dispersion wavelengths （ZDWs） is designed, and an extraordinarily high modal birefringence of 1.56×10-2 is obtained at pump wavelength ...A novel high-birefringence photonic crystal fiber （HB-PCF） with two zero-dispersion wavelengths （ZDWs） is designed, and an extraordinarily high modal birefringence of 1.56×10-2 is obtained at pump wavelength λp=1850nm. With the designed HB-PCF, the effect of the pump parameters on the modulation instability （MI） in the anomalous dispersion region close to the second ZDWs of the HB-PCF is comprehensively studied in this work. A broadband and tunable optical amplification is achieved by controlling the pump power and the pump wavelength based on the combined operation of Raman effect and cross phase modulation. By optimizing the pump parameters, the amplification bandwidth along the fiber slow axis reaches 152 nm for the pump power Pp=280W and the pump wavelength λp=1675nm, while the gain bandwidth along the fiber fast axis is 165 nm for the pump power Pp=600W and the pump wavelength λp=1818nm.展开更多
Brillouin amplification is a new method to obtain high power hundred-picosecond laser pulses for shock ignition. The laser pulse＇s intensity can be amplified to 10 GW/cm^2 through this method. In order to determine t...Brillouin amplification is a new method to obtain high power hundred-picosecond laser pulses for shock ignition. The laser pulse＇s intensity can be amplified to 10 GW/cm^2 through this method. In order to determine the near-field quality, the relationship between the Brillouin amplification gain and the B integral in the stimulated Brillouin scattering（SBS） energy transfer process was studied, and numerical simulations and calculations were carried out to explain the process. For achieving an output intensity of 10 GW/cm^2 under the condition that the effect of small–scale self-focusing is insignificant in the Brillouin amplification, the influence of the configuration parameters on the Brillouin amplification and the B integral was investigated. The results showed that the 10 GW/cm^2 high power output can be obtained by optimizing the intensities of the pump and Stokes light and choosing an appropriate SBS medium.展开更多
A new scheme of multibeam Raman amplification(MRA)is proposed in virtue of the collective mode by sharing a common scattered light.Multiple laser beams can provide a higher growth rate,but the overlapping region limit...A new scheme of multibeam Raman amplification(MRA)is proposed in virtue of the collective mode by sharing a common scattered light.Multiple laser beams can provide a higher growth rate,but the overlapping region limits the amplification length.We suggest to use a finite-duration seed to facilitate MRA in a short distance.Through two-dimensional particle-in-cell simulations,we find that two-beam Raman amplification has a much higher growth rate than that of singlebeam one.This growth rate depends on the initial seed amplitude,electron temperature,and seed duration.An empirical criterion,γ0τc=1,whereγ0 is the theoretical growth rate of MRA,is used to choose a proper duration for a higher growth rate.After a total amplification length of 320µm,the two-beam Raman amplification shows nonlinear features of pulse compression and a bow-shape wave front,indicating that the amplification has finally entered the self-similar regime.展开更多
In theory, we study the quantum tluctuatlons ot tlae suDllarmonlc renecteu nela Irom a ulplc-rc^ulltUtt IdU^ClIClatC optical parametric amplifier （OPA） inside an optical cavity. We discuss two cases, where the linew...In theory, we study the quantum tluctuatlons ot tlae suDllarmonlc renecteu nela Irom a ulplc-rc^ulltUtt IdU^ClIClatC optical parametric amplifier （OPA） inside an optical cavity. We discuss two cases, where the linewidth of the harmonic field is either much narrower or broader than the subharmonic field. Since an electromagnetically-induced-transparency （EIT）-like effect can be simulated in a triple-resonant OPA, the output spectra from a triple-resonant OPA with a squeezed vacuum input may simulate the phenomenon of the response of an EIT medium for squeezed states. This scheme can be implemented with present experimental setups.展开更多
In this paper, a new method is proposed to study the mechanism of charge collection in single event transient （SET） production in 90 nm bulk complementary metal oxide semiconductor （CMOS） technology. We find that ...In this paper, a new method is proposed to study the mechanism of charge collection in single event transient （SET） production in 90 nm bulk complementary metal oxide semiconductor （CMOS） technology. We find that different from the case in the pMOSFET, the parasitic bipolar amplification effect （bipolar effect） in the balanced inverter does not exist in the nMOSFET after the ion striking. The influence of the suhstrate process on the bipolar effect is also studied in the pMOSFET. We find that the bipolar effect can be effectively mitigated by a buried deep P＋-well layer and can be removed by a buried SO2 layer.展开更多
Objective：Duchenne muscular dystrophy （DMD） and Becker muscular dystrophy （BMD） are X-linked disorders caused by mutations in the dystrophin gene. The majority of recognized mutations are copy number changes of i...Objective：Duchenne muscular dystrophy （DMD） and Becker muscular dystrophy （BMD） are X-linked disorders caused by mutations in the dystrophin gene. The majority of recognized mutations are copy number changes of individual exons. The objective of the present study was to assess the multiplex ligation-dependent probe amplification （MLPA） effects of detection of gene mutations. Methods： Samples of 20 control males and 80 males and their mothers referred to our diagnostic facility on the clinical suspi- cion of DMD or BMD were tested by MLPA and multiplex PCR. Results ： The mean DQs for all peak of 20 control male samples was 1.02 （range from 0.83 to 1.21） by MLPA. Deletions or duplications were iden- tified in 6 out of 31 families that had been previously tested as negative by multiplex PCR. One case of complex rearrangement involving a duplication of two regions： dupEX3-9 and dupEX 17-41 were found by MLPA. Conclusions： MLPA is a highly sensitive method and rapid alternative to multiplex PCR for detec- tion of DMD and BMD.展开更多
We report on the auditory Hopf amplification contributed by the electrical energy of the hair cell during its bundle deflecting. An energy method to calculate the active force is adopted according to the electrical en...We report on the auditory Hopf amplification contributed by the electrical energy of the hair cell during its bundle deflecting. An energy method to calculate the active force is adopted according to the electrical energy consumption of the hair cell. After some experimental data was analyzed and simulated, we find that the electrical energy determines the value of the active force and enlarges the mechanical response of the hair bundle. This amplification is controlled by the cell voltage and makes the sensor a Hopf vibrator with hearing nonlinear characteristics. A velocity-dependent active force derived previously from the force-gating channel operation strongly reinforces our conclusion.展开更多
Noiseless linear amplification （NLA）, first proposed by Ralpha et al., is a nondeterministic amplification process which gives gain to the Fock state ｜n） → gn｜n）, with g being the amplification gain. We here gi...Noiseless linear amplification （NLA）, first proposed by Ralpha et al., is a nondeterministic amplification process which gives gain to the Fock state ｜n） → gn｜n）, with g being the amplification gain. We here give a general frame- work for improving the NLA scheme with arbitrary general local unitary operations. We derive the improvement in the amplification gain in 0 1 photon subspace. In particular, we study if the local unitary is composed of sin- gle mode squeezing and coherent displacement operation. Finally, numerical simulations show that local unitary operation could give a further enhancement in the amplification gain as well as the success probability, making the NLA more feasible in future optic quantum communications.展开更多
Using a pump with a multi-line spectrum to broaden the Brillouin gain bandwidth is an effective way to achieve lowdistortion amplification with high gain. Here, we theoretically and experimentally investigate the gene...Using a pump with a multi-line spectrum to broaden the Brillouin gain bandwidth is an effective way to achieve lowdistortion amplification with high gain. Here, we theoretically and experimentally investigate the generation of a broadband Brillouin gain spectrum based on multi-frequency intensity modulation in an optical fiber. The arbitrary bandwidth of the Brillouin gain spectrum of stimulated Brillouin scattering(SBS) can be obtained as expected. In our experiment, a broadband Brillouin gain spectrum with a bandwidth of about 200 MHz is demonstrated. We also achieve a low-distortion amplification of a weak signal, whose maximum magnification is 65 d B for a-68-dBm input power signal.展开更多
文摘Blasting operations,which are crucial to open-pit mine production due to their simplicity and efficiency,require precise control through accurate vibration velocity calculations.The conventional Sadowski formula mainly focuses on blast center distance but neglects the amplification effect of blasting vibration waves by terraced terrain,from which the calculated blasting vibration velocities are smaller than the actual values,affecting the safety of the project.To address this issue,our model introduces the influences of slope and time into Sadowski formula to measure safety through blast vibration displacement.In the northern section of the open-pit quartz mine in Jinchang City,Gansu Province,China,the data of a continuous blasting slope project are referred to.Our findings reveal a noticeable vibration amplification effect during blasting when a multi-stage slope platform undergoes a sudden cross-sectional change near the upper overhanging surface.The amplification vibration coefficient increases with height,while vibration waves within rocks decrease from bottom to top.Conversely,platforms without distinct crosssectional changes exhibit no pronounced amplification during blasting.In addition,the vibration intensity decreases with distance as the rock height difference change propagates.The results obtained by the proposed blast vibration displacement equation incorporating slope shape influence closely agree with real-world scenarios.According to Pearson correlation coefficient(PPMCC)analysis,the average accuracy rate of our model is 88.84%,which exceeds the conventional Sadowski formula(46.92%).
基金the National Natural Science Foundation of China(Grant No.12074233)the National Key Research and Development Program of China(Grant No.2021YFC2201802)Shanxi(1331 Project)。
文摘Quantum states are essential resource for quantum-enhanced applications.Loss incurred in the distribution channel,however,dissipates the high signal-to-noise ratio advantage enjoyed by the squeezed state.Here,we first demonstrate noise immunity enhancement by using phase-sensitive amplifier(PSA)with measurement-based noiseless linear amplifier(MB-NLA).We explore the signal transfer capability with the amplifier in a noisy channel.The MB-NLA enhanced PSA has obvious suppression effect on channel noises,especially it has improvement for the noise contaminated signal.Better performance can be achieved by flexibly adjusting amplifier parameters.With the amplifier,it is promising to overcome the entanglement-distribution loss and show its superiority in squeezing based quantum sensing.
基金supported by the National Basic Research Program of China(Grant Nos.2011CBA00200 and 2011CB921200)the National Natural Science Foundation of China(Grant Nos.60921091 and 61101137)
文摘Post-processing is indispensable in quantum key distribution （QKD）, which is aimed at sharing secret keys between two distant parties. It mainly consists of key reconciliation and privacy amplification, which is used for sharing the same keys and for distilling unconditional secret keys. In this paper, we focus on speeding up the privacy amplification process by choosing a simple multiplicative universal class of hash functions. By constructing an optimal multiplication algorithm based on four basic multiplication algorithms, we give a fast software implementation of length-adaptive privacy amplification. ＂Length-adaptive＂ indicates that the implementation of privacy amplification automatically adapts to different lengths of input blocks. When the lengths of the input blocks are 1 Mbit and 10 Mbit, the speed of privacy amplification can be as fast as 14.86 Mbps and 10.88 Mbps, respectively. Thus, it is practical for GHz or even higher repetition frequency QKD systems.
基金Nanjing Forestry University[Grant Nos.163020139,164020818,163020217 and 16302023]National Natural Science Foundation of China(5201101466).
文摘A novel coronavirus of zoonotic origin(SARSCoV-2)has recently been recognized in patients with acute respiratory disease.COVID-19 causative agent is structurally and genetically similar to SARS and bat SARS-like coronaviruses.The drastic increase in the number of coronavirus and its genome sequence have given us an unprecedented opportunity to perform bioinformatics and genomics analysis on this class of viruses.Clinical tests like PCR and ELISA for rapid detection of this virus are urgently needed for early identification of infected patients.However,these techniques are expensive and not readily available for point-of-care(POC)applications.Currently,lack of any rapid,available,and reliable POC detection method gives rise to the progression of COVID-19 as a horrible global problem.To solve the negative features of clinical investigation,we provide a brief introduction of the general features of coronaviruses and describe various amplification assays,sensing,biosensing,immunosensing,and aptasensing for the determination of various groups of coronaviruses applied as a template for the detection of SARS-CoV-2.All sensing and biosensing techniques developed for the determination of various classes of coronaviruses are useful to recognize the newly immerged coronavirus,i.e.,SARS-CoV-2.Also,the introduction of sensing and biosensing methods sheds light on the way of designing a proper screening system to detect the virus at the early stage of infection to tranquilize the speed and vastity of spreading.Among other approaches investigated among molecular approaches and PCR or recognition of viral diseases,LAMP-based methods and LFAs are of great importance for their numerous benefits,which can be helpful to design a universal platform for detection of future emerging pathogenic viruses.
文摘In order to study the altered molecular events during laryngeal carcinogenesis and elucidate the role of Haras oncogene amplification and mutation. we have examined their profile by polymerase chain reaction (PCR) and selective oligonucleotide hybridization. We analyzed the mutational status of codon 12 of Haras in 22 laryngeal carcinomas and 10 normal tissues. and found that 7 of 22 laryngeal carcinomas contained a Ha-ras mutation at codon 12. The frequency of mutation was 32%. None of the normal tissues revealed mutation. Moreover. no amplification was found in cancers when compared to the normal. Ourfindings indicated that the activated Ha-ras gene existed in laryngeal carcinoma. and activation of the Haras gene by mutation at codon 12 might play a key role in laryngeal carcinogenesis.
基金supported by the National Natural Science of China(Grant No.61376109)
文摘FinFET technologies are becoming the mainstream process as technology scales down. Based on a 28-nm bulk p- FinFET device, we have investigated the fin width and height dependence of bipolar amplification for heavy-ion-irradiated FinFETs by 3D TCAD numerical simulation. Simulation results show that due to a well bipolar conduction mechanism rather than a channel （fin） conduction path, the transistors with narrower fins exhibit a diminished bipolar amplification effect, while the fin height presents a trivial effect on the bipolar amplification and charge collection. The results also indicate that the single event transient （SET） pulse width can be mitigated about 35% at least by optimizing the ratio of fin width and height, which can provide guidance for radiation-hardened applications in bulk FinFET technology.
基金Project supported by the National Natural Science Foundation of China (Grant Nos. 60836004, 61076025, and 61006070)the Specialized Research Fund for the Doctoral Program of Higher Education of China (Grant No. 20104307120006)
文摘Using three-dimensional technology computer-aided design （TCAD） simulation, parasitic bipolar amplification in a single event transient （SET） current of a single transistor and its temperature dependence are studied. We quantify the contributions of different current components in a SET current pulse, and it is found that the proportion of parasitic bipolar amplification in total collected charge is about 30% in both ]30-nm and 90-nm technologies. The temperature dependence of parasitic bipolar amplification and the mechanism of the SET pulse are also investigated and quantified. The results show that the proportion of charge induced by parasitic bipolar increases with rising temperature, which illustrates that the parasitic bipolar amplification plays an important role in the charge collection of a single transistor.
基金the Science and Technology Joint Project of the Yangtze River Delta (19395810100)Shanghai Agriculture Project (19391901500)+2 种基金the National Key Research and Development Program of China (2016YFD0501101)the Shanghai Science and Technology Innovation Foundation (19441903900 and 19XD1433000)Project of National Natural Science Foundation of China (82003705)。
文摘The rapid and accurate detection of peanuts and soybeans allergen is important to the food safety. In this study, Cu-TCPP nanosheet, a kind of ultra-thin metal-organic framework(MOF)was synthesized and applied in loop-mediated isothermal amplification(named Cu-TCPP@LAMP), which can inhibit the non-specific amplification by absorbing and precise temperature releasing of single primer. As thus, Cu-TCPP@LAMP can achieve high sensitivity and specific amplification of the target gene. As a result, peanut and soybean allergens genes contained in food were successfully detected with a favorable detection sensitivity(5 ng/μL for peanuts and 10 ng/μL for soybeans)and reliable repeatability(The coefficient of variation was 3.38% for peanuts and 3.33% for soybeans). Moreover, the established method was utilized for detection of several commercial products, and had a high consistency with the standard method. Apart from food allergens, this novel assay can be widely used in other areas, such as pathogen detection, tumor nucleic acid detection and so on.
基金Supported by the National Natural Science Foundation of China under Grant No 11374118the Science Foundation of Hubei Province under Grant No 2013CFB289
文摘The sense of mammalian hearing exhibits nonlinear phenomena which are most significant to hearing function, such as nonlinear dynamic compression, nonlinear tuning and combination tones. These nonlinear phenomena are suggested to originate from the Hopf amplification within the cochlea, while the mechanism underlying the Hopf amplification remains elusive. According to the experimental results of force-gating channel operation in hair cells, through a theoretic model, this work reveals a velocity-dependent open probability of force-gating channels in auditory hair cells, and a velocity-dependent active force produced by the force-gating channel operating, which makes sensors hear typical Hopf vibrators with nonlinear hearing phenomena.
基金supported by the National Natural Science Foundation of China(No.51105193)the Natural Science Foundation of Jiangsu Province(No.BK20131362)+1 种基金the Priority Academic Program Development of Jiangsu Higher Education InstitutionsJiangsu Students′Platform for Innovation and Entrepreneurship Training Program(No.201613655016X)
文摘Piezoelectric friction-inertial motor is known for its promise for a long-range and high-resolution motion.The movement of the slider/rotor of the motor is achieved by stick-slip effect.We report a relaxor-based-ferroelectric-single-crystal cymbal actuator and a miniature piezoelectric friction-inertial linear motor(abbreviated as PFILM)fabricated with the cymbal actuator.The cymbal actuator is fabricated with a 10 mm diameter disk of 0.70Pb(Mg_(1/3)Nb_(2/3))O_3-0.30PbTiO_3 single crystal.The displacement of the cymbal actuator increases almost proportionally from 0to 23μm with driving voltage up to 500 V,and the minimal hysteresis is observed.The cymbalPFILM with 20 mm motion range works under driving voltage frequency of ca.100 Hz to ca.5kHz,the fastest speed is obtained with 3.5kHz and the no-load speed is 14mm/s and the maximum thrust force is 98 mN.Compared with a PFILM based on multilayer piezoelectric ceramic,the proposed motor has a larger stroke under DC/quasistatic input voltage in fine motion mode,but a smaller driving force in long-travel mode due to lower resonance frequency.
基金Project supported by the National Natural Science Foundation of China(Grant Nos.11474168 and 11747161)the Priority Academic Program Development of Jiangsu Higher Education Institutions,Chinathe China Postdoctoral Science Foundation(Grant No.2018M642293)
文摘Single-photon entanglement(SPE) is an important source in quantum communication. In this paper, we put forward a single-photon-assisted noiseless linear amplification protocol to protect the SPE of an arbitrary polarization–time-bin qudit from the photon transmission loss caused by the practical channel noise. After the amplification, the fidelity of the SPE can be effectively increased. Meanwhile, the encoded polarization–time-bin features of the qudit can be well preserved. The protocol can be realized under the current experimental conditions. Moreover, the amplification protocol can be extended to resist complete photon loss and partial photon loss during the photon transmission. After the amplification, we can not only increase the fidelity of the target state, but also solve the decoherence problem simultaneously. Based on the above features, our amplification protocol may be useful in future quantum communication.
基金the National Natural Science Foundation of China(Grant No.11226148)the Scientific Research Foundation of Zhejiang Province,China(Grant No.LY12F05006)the Education Department Foundation of Zhejiang Province,China(Grant No.Y201121906)
文摘A novel high-birefringence photonic crystal fiber （HB-PCF） with two zero-dispersion wavelengths （ZDWs） is designed, and an extraordinarily high modal birefringence of 1.56×10-2 is obtained at pump wavelength λp=1850nm. With the designed HB-PCF, the effect of the pump parameters on the modulation instability （MI） in the anomalous dispersion region close to the second ZDWs of the HB-PCF is comprehensively studied in this work. A broadband and tunable optical amplification is achieved by controlling the pump power and the pump wavelength based on the combined operation of Raman effect and cross phase modulation. By optimizing the pump parameters, the amplification bandwidth along the fiber slow axis reaches 152 nm for the pump power Pp=280W and the pump wavelength λp=1675nm, while the gain bandwidth along the fiber fast axis is 165 nm for the pump power Pp=600W and the pump wavelength λp=1818nm.
基金Project supported by the National Natural Science Foundation of China(Grant Nos.61378007 and 61138005)the Fundamental Research Funds for the Central Universities,China(Grant No.HIT.IBRSEM.A.201409)
文摘Brillouin amplification is a new method to obtain high power hundred-picosecond laser pulses for shock ignition. The laser pulse＇s intensity can be amplified to 10 GW/cm^2 through this method. In order to determine the near-field quality, the relationship between the Brillouin amplification gain and the B integral in the stimulated Brillouin scattering（SBS） energy transfer process was studied, and numerical simulations and calculations were carried out to explain the process. For achieving an output intensity of 10 GW/cm^2 under the condition that the effect of small–scale self-focusing is insignificant in the Brillouin amplification, the influence of the configuration parameters on the Brillouin amplification and the B integral was investigated. The results showed that the 10 GW/cm^2 high power output can be obtained by optimizing the intensities of the pump and Stokes light and choosing an appropriate SBS medium.
基金supported by the Strategic Priority Research Program of Chinese Academy of Sciences(Grant No.XDA25050700)the National Natural Science Foundation of China(Grant No.11805062)+2 种基金Science Challenge Project(Grant No.TZ2016005)Natural Science Foundation of Hunan Province,China(Grant Nos.2020JJ5029 and 2020JJ5031)the Project of Science and Technology on Plasma Physics Laboratory(Grant No.6142A04190111)。
文摘A new scheme of multibeam Raman amplification(MRA)is proposed in virtue of the collective mode by sharing a common scattered light.Multiple laser beams can provide a higher growth rate,but the overlapping region limits the amplification length.We suggest to use a finite-duration seed to facilitate MRA in a short distance.Through two-dimensional particle-in-cell simulations,we find that two-beam Raman amplification has a much higher growth rate than that of singlebeam one.This growth rate depends on the initial seed amplitude,electron temperature,and seed duration.An empirical criterion,γ0τc=1,whereγ0 is the theoretical growth rate of MRA,is used to choose a proper duration for a higher growth rate.After a total amplification length of 320µm,the two-beam Raman amplification shows nonlinear features of pulse compression and a bow-shape wave front,indicating that the amplification has finally entered the self-similar regime.
基金supported by the National Basic Research Program of China (Grant No. 2011CB921601)the National Natural Science Foundation of China for Excellent Research Team (Grant No. 61121064)+1 种基金the Specialized Research Fund for the Doctoral Program of Higher Education of China (Grant No. 20111401130001)the Graduate Outstanding Innovation Item of Shanxi Province, China (Grant No. 20113001)
文摘In theory, we study the quantum tluctuatlons ot tlae suDllarmonlc renecteu nela Irom a ulplc-rc^ulltUtt IdU^ClIClatC optical parametric amplifier （OPA） inside an optical cavity. We discuss two cases, where the linewidth of the harmonic field is either much narrower or broader than the subharmonic field. Since an electromagnetically-induced-transparency （EIT）-like effect can be simulated in a triple-resonant OPA, the output spectra from a triple-resonant OPA with a squeezed vacuum input may simulate the phenomenon of the response of an EIT medium for squeezed states. This scheme can be implemented with present experimental setups.
基金Project supported by the Key Program of the National Natural Science Foundation of China(Grant No.60836004)the National Natural Science Foundation of China(Grant Nos.61006070 and 61076025)
文摘In this paper, a new method is proposed to study the mechanism of charge collection in single event transient （SET） production in 90 nm bulk complementary metal oxide semiconductor （CMOS） technology. We find that different from the case in the pMOSFET, the parasitic bipolar amplification effect （bipolar effect） in the balanced inverter does not exist in the nMOSFET after the ion striking. The influence of the suhstrate process on the bipolar effect is also studied in the pMOSFET. We find that the bipolar effect can be effectively mitigated by a buried deep P＋-well layer and can be removed by a buried SO2 layer.
文摘Objective：Duchenne muscular dystrophy （DMD） and Becker muscular dystrophy （BMD） are X-linked disorders caused by mutations in the dystrophin gene. The majority of recognized mutations are copy number changes of individual exons. The objective of the present study was to assess the multiplex ligation-dependent probe amplification （MLPA） effects of detection of gene mutations. Methods： Samples of 20 control males and 80 males and their mothers referred to our diagnostic facility on the clinical suspi- cion of DMD or BMD were tested by MLPA and multiplex PCR. Results ： The mean DQs for all peak of 20 control male samples was 1.02 （range from 0.83 to 1.21） by MLPA. Deletions or duplications were iden- tified in 6 out of 31 families that had been previously tested as negative by multiplex PCR. One case of complex rearrangement involving a duplication of two regions： dupEX3-9 and dupEX 17-41 were found by MLPA. Conclusions： MLPA is a highly sensitive method and rapid alternative to multiplex PCR for detec- tion of DMD and BMD.
基金Supported by the National Natural Science Foundation of China under Grant Nos 11374118 and 90820001the Science Foundation of Hubei Province under Grant No 2013CFB289
文摘We report on the auditory Hopf amplification contributed by the electrical energy of the hair cell during its bundle deflecting. An energy method to calculate the active force is adopted according to the electrical energy consumption of the hair cell. After some experimental data was analyzed and simulated, we find that the electrical energy determines the value of the active force and enlarges the mechanical response of the hair bundle. This amplification is controlled by the cell voltage and makes the sensor a Hopf vibrator with hearing nonlinear characteristics. A velocity-dependent active force derived previously from the force-gating channel operation strongly reinforces our conclusion.
基金Supported by the National Natural Science Foundation of China under Grant Nos 11304013,11204197,11204379 and 11074244the National Basic Research Program of China under Grant No 2011CBA00200+1 种基金the Doctor Science Research Foundation of Ministry of Education of China under Grant No 20113402110059Civil Aerospace 2013669
文摘Noiseless linear amplification （NLA）, first proposed by Ralpha et al., is a nondeterministic amplification process which gives gain to the Fock state ｜n） → gn｜n）, with g being the amplification gain. We here give a general frame- work for improving the NLA scheme with arbitrary general local unitary operations. We derive the improvement in the amplification gain in 0 1 photon subspace. In particular, we study if the local unitary is composed of sin- gle mode squeezing and coherent displacement operation. Finally, numerical simulations show that local unitary operation could give a further enhancement in the amplification gain as well as the success probability, making the NLA more feasible in future optic quantum communications.
基金Project supported by the National Natural Science Foundation of China(Grant No.61605034)
文摘Using a pump with a multi-line spectrum to broaden the Brillouin gain bandwidth is an effective way to achieve lowdistortion amplification with high gain. Here, we theoretically and experimentally investigate the generation of a broadband Brillouin gain spectrum based on multi-frequency intensity modulation in an optical fiber. The arbitrary bandwidth of the Brillouin gain spectrum of stimulated Brillouin scattering(SBS) can be obtained as expected. In our experiment, a broadband Brillouin gain spectrum with a bandwidth of about 200 MHz is demonstrated. We also achieve a low-distortion amplification of a weak signal, whose maximum magnification is 65 d B for a-68-dBm input power signal.
