Based on the thermal and velocity layer's theory,the experimental setup was established on large space atrium under nozzle outlet. A series of winter experiments were accomplished and the following conclusions cou...Based on the thermal and velocity layer's theory,the experimental setup was established on large space atrium under nozzle outlet. A series of winter experiments were accomplished and the following conclusions could be drawn. At the sunny day of winter in Shanghai,the thermal and velocity layer are similar. The height of the both layer is 10-30 mm,and the temperature gratitude is 5-10 ℃ /m. Decreasing the angle of the nozzle outlet can increase the layer height dramatically. The maximum temperature difference of the occupant zone has relation with the angle of the nozzle outlet. The less the angle of the nozzle outlet is set,the greater the temperature difference is. The occupant temperature differences at these angles of the nozzle outlet are 5.1-4.4 ℃. The velocity of the wind is 0.02 and 0.17 m/s and they can accord with design demand. So,it can decrease the temperature gratitude by about 30% and it can save 10%-15% energy consumption.展开更多
In this study a 10-storied residential building model was employed to clarify the ventilation characteristics of the atrium and the rooms,which were effected by the different forms of lateral openings.The experiment w...In this study a 10-storied residential building model was employed to clarify the ventilation characteristics of the atrium and the rooms,which were effected by the different forms of lateral openings.The experiment was conducted under the combined effect of wind force and thermal buoyancy,and the similarity requirements were satisfied.The results have shown that the different forms of lateral openings cause the different ventilation effect of the building,and also have some certain regularity.The conclusions provide a theoretical foundation for how to use the ventilation of atrium better in high-rise residential building.展开更多
右心房结构和功能在维持心血管系统稳态中扮演关键角色,其形态重构及功能异常与多种心血管疾病进程紧密相连。近年来,随着心脏磁共振(cardiac magnetic resonance,CMR)技术的快速发展,其在无创评估心脏解剖、功能及心肌组织病理特征方...右心房结构和功能在维持心血管系统稳态中扮演关键角色,其形态重构及功能异常与多种心血管疾病进程紧密相连。近年来,随着心脏磁共振(cardiac magnetic resonance,CMR)技术的快速发展,其在无创评估心脏解剖、功能及心肌组织病理特征方面展现出独特优势,为右心房功能的精确评价提供了新的视角和方法。本文重点阐述CMR评估右心房功能的常用参数并深入探讨其在多种心血管疾病中的临床应用,指出当前CMR在右心房功能评估领域的研究不足和挑战,指明未来研究方向。本文旨在提高对CMR评估右心房功能的全面认识,促进其在心血管疾病诊疗中的广泛应用,为疾病的早期诊断、病情评估及预后判断提供参考。展开更多
目的:探讨不同强度耐力运动对大鼠心房Ⅰ型胶原蛋白(Col-I)和Ⅲ型胶原蛋白(Col-III)的影响,并研究结缔组织生长因子(CTGF)的表达变化,为探究运动性心房纤颤的发生机制提供依据。方法:24只健康雄性SD大鼠随机分为安静组、中强度组和大强...目的:探讨不同强度耐力运动对大鼠心房Ⅰ型胶原蛋白(Col-I)和Ⅲ型胶原蛋白(Col-III)的影响,并研究结缔组织生长因子(CTGF)的表达变化,为探究运动性心房纤颤的发生机制提供依据。方法:24只健康雄性SD大鼠随机分为安静组、中强度组和大强度组,每组8只。进行16周的运动训练,每周训练5天,每天1小时。16周末处死大鼠摘取心脏后分离出右心房,应用RT-PCR、免疫荧光化学和Western Blot技术测定Col-I、Col-III和CTGF基因与蛋白的表达。结果:与安静组相比,大强度组Col-I m RNA和蛋白的表达显著升高(P<0.05和P<0.01);Col-III m RNA增加但无显著性,蛋白表达显著性升高(P<0.01);Col-I/Col-III蛋白表达的比值显著升高(P<0.01);CTGF m RNA和蛋白的表达均显著升高(P<0.05)。与安静组相比,中强度组Col-I m RNA和蛋白的表达增加,但无统计学差异;Col-III m RNA表达显著性降低(P<0.01),蛋白表达无显著性变化;Col-I/Col-III蛋白表达比值增高,但无显著性;CTGF m RNA表达增高而蛋白表达降低,但均无显著性。结论:长期大强度运动可导致大鼠心房Col-I和Col-III显著增加、Col-I/Col-III比例发生失衡,可能与长期大强度运动诱导大鼠心房CTGF的表达增加有关,构成了运动性心房纤颤发生的重要病理机制之一。展开更多
基金Project(09YZ229) supported by Innovation Program of Shanghai Municipal Education Commission, ChinaProject(J50502) supported by Leading Academic Discipline of Shanghai Municipal Education Commission,China+2 种基金Project(50478113) supported by the National Natural Science Foundation of ChinaProject(2006BAJ02A05) supported by the National Key Technology R&D Program,ChinaProject(08DZ1203600) supported by the Shanghai Municipal Sciences and Technology Committee,China
文摘Based on the thermal and velocity layer's theory,the experimental setup was established on large space atrium under nozzle outlet. A series of winter experiments were accomplished and the following conclusions could be drawn. At the sunny day of winter in Shanghai,the thermal and velocity layer are similar. The height of the both layer is 10-30 mm,and the temperature gratitude is 5-10 ℃ /m. Decreasing the angle of the nozzle outlet can increase the layer height dramatically. The maximum temperature difference of the occupant zone has relation with the angle of the nozzle outlet. The less the angle of the nozzle outlet is set,the greater the temperature difference is. The occupant temperature differences at these angles of the nozzle outlet are 5.1-4.4 ℃. The velocity of the wind is 0.02 and 0.17 m/s and they can accord with design demand. So,it can decrease the temperature gratitude by about 30% and it can save 10%-15% energy consumption.
基金Supported by the National Natural Science Foundation of China(50778064)Hunan Natural Science Foundation(07jj6088)
文摘In this study a 10-storied residential building model was employed to clarify the ventilation characteristics of the atrium and the rooms,which were effected by the different forms of lateral openings.The experiment was conducted under the combined effect of wind force and thermal buoyancy,and the similarity requirements were satisfied.The results have shown that the different forms of lateral openings cause the different ventilation effect of the building,and also have some certain regularity.The conclusions provide a theoretical foundation for how to use the ventilation of atrium better in high-rise residential building.
文摘右心房结构和功能在维持心血管系统稳态中扮演关键角色,其形态重构及功能异常与多种心血管疾病进程紧密相连。近年来,随着心脏磁共振(cardiac magnetic resonance,CMR)技术的快速发展,其在无创评估心脏解剖、功能及心肌组织病理特征方面展现出独特优势,为右心房功能的精确评价提供了新的视角和方法。本文重点阐述CMR评估右心房功能的常用参数并深入探讨其在多种心血管疾病中的临床应用,指出当前CMR在右心房功能评估领域的研究不足和挑战,指明未来研究方向。本文旨在提高对CMR评估右心房功能的全面认识,促进其在心血管疾病诊疗中的广泛应用,为疾病的早期诊断、病情评估及预后判断提供参考。
文摘目的:探讨不同强度耐力运动对大鼠心房Ⅰ型胶原蛋白(Col-I)和Ⅲ型胶原蛋白(Col-III)的影响,并研究结缔组织生长因子(CTGF)的表达变化,为探究运动性心房纤颤的发生机制提供依据。方法:24只健康雄性SD大鼠随机分为安静组、中强度组和大强度组,每组8只。进行16周的运动训练,每周训练5天,每天1小时。16周末处死大鼠摘取心脏后分离出右心房,应用RT-PCR、免疫荧光化学和Western Blot技术测定Col-I、Col-III和CTGF基因与蛋白的表达。结果:与安静组相比,大强度组Col-I m RNA和蛋白的表达显著升高(P<0.05和P<0.01);Col-III m RNA增加但无显著性,蛋白表达显著性升高(P<0.01);Col-I/Col-III蛋白表达的比值显著升高(P<0.01);CTGF m RNA和蛋白的表达均显著升高(P<0.05)。与安静组相比,中强度组Col-I m RNA和蛋白的表达增加,但无统计学差异;Col-III m RNA表达显著性降低(P<0.01),蛋白表达无显著性变化;Col-I/Col-III蛋白表达比值增高,但无显著性;CTGF m RNA表达增高而蛋白表达降低,但均无显著性。结论:长期大强度运动可导致大鼠心房Col-I和Col-III显著增加、Col-I/Col-III比例发生失衡,可能与长期大强度运动诱导大鼠心房CTGF的表达增加有关,构成了运动性心房纤颤发生的重要病理机制之一。
