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电子细胞模型Analog-Cell中前体mRNA剪接过程的模拟与研究 被引量:1
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作者 欧阳丹彤 王珏 +1 位作者 韩霄松 卢欣华 《软件学报》 EI CSCD 北大核心 2012年第9期2273-2284,共12页
真核细胞前体mRNA的剪接加工包含内含子剪切和外显子拼接两个过程,是真核细胞基因表达过程中的一个重要环节.针对这一环节,提出了一种模拟真核细胞前体mRNA内含子剪切及其选择性剪接的算法,并在自主研发的电子细胞模型Analog-Cell中实... 真核细胞前体mRNA的剪接加工包含内含子剪切和外显子拼接两个过程,是真核细胞基因表达过程中的一个重要环节.针对这一环节,提出了一种模拟真核细胞前体mRNA内含子剪切及其选择性剪接的算法,并在自主研发的电子细胞模型Analog-Cell中实现了该算法,且获得了符合生物学原理的模拟结果.模拟结果表明,该算法可使剪接体高效、准确地模拟内含子的剪接过程,并形成套索结构,同时有选择地将外显子片段拼接起来,最终形成成熟的mRNA. 展开更多
关键词 电子细胞 analog-Cell 选择性剪接 前体mRNA的剪接
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Feature evaluation and extraction based on neural network in analog circuit fault diagnosis 被引量:16
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作者 Yuan Haiying Chen Guangju Xie Yongle 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2007年第2期434-437,共4页
Choosing the right characteristic parameter is the key to fault diagnosis in analog circuit. The feature evaluation and extraction methods based on neural network are presented. Parameter evaluation of circuit feature... Choosing the right characteristic parameter is the key to fault diagnosis in analog circuit. The feature evaluation and extraction methods based on neural network are presented. Parameter evaluation of circuit features is realized by training results from neural network; the superior nonlinear mapping capability is competent for extracting fault features which are normalized and compressed subsequently. The complex classification problem on fault pattern recognition in analog circuit is transferred into feature processing stage by feature extraction based on neural network effectively, which improves the diagnosis efficiency. A fault diagnosis illustration validated this method. 展开更多
关键词 Fault diagnosis Feature extraction analog circuit Neural network Principal component analysis.
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Wavelet neural network based fault diagnosis in nonlinear analog circuits 被引量:16
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作者 Yin Shirong Chen Guangju Xie Yongle 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2006年第3期521-526,共6页
The theories of diagnosing nonlinear analog circuits by means of the transient response testing are studled. Wavelet analysis is made to extract the transient response signature of nonlinear circuits and compress the ... The theories of diagnosing nonlinear analog circuits by means of the transient response testing are studled. Wavelet analysis is made to extract the transient response signature of nonlinear circuits and compress the signature dada. The best wavelet function is selected based on the between-category total scatter of signature. The fault dictionary of nonlinear circuits is constructed based on improved back-propagation(BP) neural network. Experimental results demonstrate that the method proposed has high diagnostic sensitivity and fast fault identification and deducibility. 展开更多
关键词 fault diagnosis nonlinear analog circuits wavelet analysis neural networks.
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Analog Discovery 2在模拟电子技术实验案例中的应用 被引量:8
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作者 张涛 黄大刚 +1 位作者 包秀娟 王鸿鹏 《实验技术与管理》 CAS 北大核心 2020年第7期176-179,共4页
通过实际案例介绍了Analog Discovery 2(简称AD2)在模拟电子技术实验中的应用。简要介绍了AD2的功能和使用方法,并且以模电实验中的积分电路为例,详细介绍了基于Multisim、AD2和Waveforms开展实验的步骤和结果,并对仿真结果和实际结果... 通过实际案例介绍了Analog Discovery 2(简称AD2)在模拟电子技术实验中的应用。简要介绍了AD2的功能和使用方法,并且以模电实验中的积分电路为例,详细介绍了基于Multisim、AD2和Waveforms开展实验的步骤和结果,并对仿真结果和实际结果进行对比。教学实践表明,将该套件应用在模电实验中,弥补了传统虚拟仿真实验的不足,摆脱了空间、时间限制,灵活便携,可操作性强,便于拓展,结果清楚直观,值得推广。 展开更多
关键词 analog Discovery 2 虚拟仿真技术 模拟电子技术实验
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Analogies between Density Functional Theory Response Kernels and Derivatives of Thermodynamic State Functions 被引量:1
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作者 GEERLINGS Paul DE PROFT Frank FIAS Stijn 《物理化学学报》 SCIE CAS CSCD 北大核心 2018年第6期699-707,共9页
In view of its use as reactivity theory,Conceptual Density Functional Theory(DFT),introduced by Parr et al.,has mainly concentrated up to now on the E = E[N,v] functional.However,different ensemble representations can... In view of its use as reactivity theory,Conceptual Density Functional Theory(DFT),introduced by Parr et al.,has mainly concentrated up to now on the E = E[N,v] functional.However,different ensemble representations can be used involving other variables also,such as ρ and μ.In this study,these different ensemble representations(E,?,F,and R) are briefly reviewed.Particular attention is then given to the corresponding second-order(functional) derivatives,and their analogieswith the second-order derivatives of thermodynamic state functions U,F,H,and G,which are related to each other via Legendre transformations,just as the DFT functionals(Nalewajski and Parr,1982).Starting from an analysis of the convexity/concavity of the DFT functionals,for which explicit proofs are discussed for some cases,the positive/negative definiteness of the associated kernels is derived and a detailed comparison is made with the thermodynamic derivatives.The stability conditions in thermodynamics are similar in structure to the convexity/concavity conditions for the DFT functionals.Thus,the DFT functionals are scrutinized based on the convexity/concavity of their two variables,to yield the possibility of establishing a relationship between the three second-order reactivity descriptors derived from the considered functional.Considering two ensemble representations,F and ?,F is eliminated as it has two dependent(extensive)variables,N and ρ.For ?,on the other hand,which is concave for both of its intensive variables(μ and υ),an inequality is derived from its three second-order(functional) derivatives:the global softness,the local softness,and the softness kernel.Combined with the negative value of the diagonal element of the linear response function,this inequality is shown to be compatible with the Berkowitz-Parr relationship,which relates the functional derivatives of ρ with υ,at constant N and μ.This was recently at stake upon quantifying Kohn's Nearsightedness of Electronic Matter.The analogy of the resulting inequality and the thermodynamic inequality for the G derivatives is highlighted.Potential research paths for this study are briefly addressed;the analogies between finite-temperature DFT response functions and their thermodynamic counterparts and the quest for analogous relationships,as derived in this paper,for DFT functionals that are analogues of entropy-dimensioned thermodynamic functions such as the Massieu function. 展开更多
关键词 Conceptual DFT RESPONSE KERNELS analogY with lhermodynamics Stability-concavity/convexity
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Data-driven fault diagnosis method for analog circuits based on robust competitive agglomeration 被引量:1
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作者 Rongling Lang Zheping Xu Fei Gao 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2013年第4期706-712,共7页
The data-driven fault diagnosis methods can improve the reliability of analog circuits by using the data generated from it. The data have some characteristics, such as randomness and incompleteness, which lead to the ... The data-driven fault diagnosis methods can improve the reliability of analog circuits by using the data generated from it. The data have some characteristics, such as randomness and incompleteness, which lead to the diagnostic results being sensitive to the specific values and random noise. This paper presents a data-driven fault diagnosis method for analog circuits based on the robust competitive agglomeration (RCA), which can alleviate the incompleteness of the data by clustering with the competing process. And the robustness of the diagnostic results is enhanced by using the approach of robust statistics in RCA. A series of experiments are provided to demonstrate that RCA can classify the incomplete data with a high accuracy. The experimental results show that RCA is robust for the data needed to be classified as well as the parameters needed to be adjusted. The effectiveness of RCA in practical use is demonstrated by two analog circuits. 展开更多
关键词 DATA-DRIVEN fault diagnosis analog circuit robust competitive agglomeration (RCA).
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Multi-narrowband signals receiving method based on analog-to-information convertor and block sparsity 被引量:2
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作者 Hongyi Xu Haiqing Jiang Chaozhu Zhang 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2017年第4期643-653,共11页
The analog-to-information convertor (AIC) is a successful practice of compressive sensing (CS) theory in the analog signal acquisition. This paper presents a multi-narrowband signals sampling and reconstruction model ... The analog-to-information convertor (AIC) is a successful practice of compressive sensing (CS) theory in the analog signal acquisition. This paper presents a multi-narrowband signals sampling and reconstruction model based on AIC and block sparsity. To overcome the practical problems, the block sparsity is divided into uniform block and non-uniform block situations, and the block restricted isometry property and sub-sampling limit in different situations are analyzed respectively in detail. Theoretical analysis proves that using the block sparsity in AIC can reduce the restricted isometric constant, increase the reconstruction probability and reduce the sub -sampling rate. Simulation results show that the proposed model can complete sub -sampling and reconstruction for multi-narrowband signals. This paper extends the application range of AIC from the finite information rate signal to the multi-narrowband signals by using the potential relevance of support sets. The proposed receiving model has low complexity and is easy to implement, which can promote the application of CS theory in the radar receiver to reduce the burden of analog-to digital convertor (ADC) and solve bandwidth limitations of ADC. 展开更多
关键词 compressive sensing (CS) block sparsity analog-to-information convertor (AIC) multi-narrowband signals
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Robust Fault Diagnosis of Analog Circuits with Tolerances
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作者 Ying Deng1, Yigang He1 , Xu He2 ,Yichuang Sun3 1. College of Electrical and Information Engineering,Hunan University, 410082, Changsha, Hunan, China 2. Department of Computer Science, Hunan University, 410082, Changsha, Hunan, China 3. Department of Ele 《湖南大学学报(自然科学版)》 EI CAS CSCD 2000年第S2期133-138,共6页
A method for robust analog fault diagnosis using hybrid neural networks is proposed. The primary focus of the paper is to provide robust diagnosis using a mechanism to deal with the problem of element tolerances and r... A method for robust analog fault diagnosis using hybrid neural networks is proposed. The primary focus of the paper is to provide robust diagnosis using a mechanism to deal with the problem of element tolerances and reduce testing time. The proposed approach is based on the fault dictionary diagnosis method and backward propagation neural network (BPNN) and the adaptive resonance theory (ART) neural network. Simulation results show that the method is robust and fast for fault diagnosis of analog circuits with tolerances. 展开更多
关键词 analog CIRCUITS FAULT diagnosis TOLERANCES Artificial NEURAL networ|
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Discovery of a geomorphological analog to Martian araneiforms in the Qaidam Basin,Tibetan Plateau
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作者 Shengxing Zhang Yiliang Li Wei Leng 《中国科学技术大学学报》 CAS CSCD 北大核心 2024年第5期1-9,I0006,共10页
Araneiforms are spider-like ground patterns that are widespread in the southern polar regions of Mars.A gas erosion process driven by the seasonal sublimation of CO_(2)ice was proposed as an explanation for their form... Araneiforms are spider-like ground patterns that are widespread in the southern polar regions of Mars.A gas erosion process driven by the seasonal sublimation of CO_(2)ice was proposed as an explanation for their formation,which cannot occur on Earth due to the high climatic temperature.In this study,we propose an alternative mechanism that attrib-utes the araneiform formation to the erosion of upwelling salt water from the subsurface,relying on the identification of the first terrestrial analog found in a playa of the Qaidam Basin on the northern Tibetan Plateau.Morphological analysis indicates that the structures in the Qaidam Basin have fractal features comparable to araneiforms on Mars.A numerical model is developed to investigate the araneiform formation driven by the water-diffusion mechanism.The simulation res-ults indicate that the water-diffusion process,under varying ground conditions,may be responsible for the diverse aranei-form morphologies observed on both Earth and Mars.Our numerical simulations also demonstrate that the orientations of the saltwater diffusion networks are controlled by pre-existing polygonal cracks,which is consistent with observations of araneiforms on Mars and Earth.Our study thus suggests that a saltwater-related origin of the araneiform is possible and has significant implications for water searches on Mars. 展开更多
关键词 araneiform landform subsurface water Qaidam Basin Mars analog fractal simulations
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LG电子选用Analog Devices和TTPCom的无线技术为手机加入EDGE功能
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《电信科学》 北大核心 2004年第3期88-88,共1页
关键词 LG电子公司 analog Devices TTPCom公司 无线技术 手机 EDGE功能
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Signal modulating noise effect in bistable stochastic resonance systems and its analog simulation
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作者 肖方红 闫桂荣 谢世成 《Journal of Central South University of Technology》 EI 2006年第5期595-597,共3页
The effect of signal modulating noise in bistable stochastic resonance systems was studied theoretically and experimentally. A mathematical analysis was made on the bistable stochastic resonance model with small syste... The effect of signal modulating noise in bistable stochastic resonance systems was studied theoretically and experimentally. A mathematical analysis was made on the bistable stochastic resonance model with small system parameters. An analogue circuit was designed to perform the effect. The effect of signal modulating noise was shown in the analog simulation experiment. The analog experiment was conducted for two sinusoidal signals with different frequencies. The results show that there are a sinusoidal component corresponding to the input sinusoidal signal and a noise component presented as a Wiener process corresponding to the input white noise in the system output. By properly selecting system parameters, the effect of signal modulating noise can be manifested in the system output. 展开更多
关键词 signal modulating noise effect bistable system stochastic resonance analog simulation
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Reaction of N-phosphoryl alanine with uridine assisted by polymer nucleic acid analogs
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《厦门大学学报(自然科学版)》 CAS CSCD 北大核心 1999年第S1期198-198,共1页
关键词 acid Reaction of N-phosphoryl alanine with uridine assisted by polymer nucleic acid analogs
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Study on the Allosteric Modulators of Muscarinic M_2-Receptors: Synthesis of Unsymmetrical Analogous of W84
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作者 RuntaoLi UlrikeHolzgrabe 《厦门大学学报(自然科学版)》 CAS CSCD 北大核心 1999年第S1期450-450,共1页
关键词 Study on the Allosteric Modulators of Muscarinic M2-Receptors Synthesis of Unsymmetrical analogous of W84
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Study on the Allosteric Modulators of Muscarinic M_2-Receptors Ⅱ: Synthesis of W84 Analogous with PiperazinylDithiocarbonate
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作者 RuntaoLi UlrikeHolzgrabe 《厦门大学学报(自然科学版)》 CAS CSCD 北大核心 1999年第S1期451-451,共1页
关键词 Study on the Allosteric Modulators of Muscarinic M2-Receptors Synthesis of W84 analogous with PiperazinylDithiocarbonate
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Analog-sensitive蛋白激酶研究系统在植物病原真菌中的建立
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作者 孙忠娟 刘倩倩 +2 位作者 郭雨纤 王光辉 王晨芳 《生物技术通报》 CAS CSCD 北大核心 2022年第11期49-57,共9页
常用的基因敲除技术无法应用于某些特殊激酶的研究,旨为在植物病原真菌中建立基于蛋白激酶人工改造的analog-sensitive蛋白激酶研究系统,为蛋白激酶的研究提供新的思路和方法。采用网站预测蛋白激酶的“守门员”残基,用载体回补法对其... 常用的基因敲除技术无法应用于某些特殊激酶的研究,旨为在植物病原真菌中建立基于蛋白激酶人工改造的analog-sensitive蛋白激酶研究系统,为蛋白激酶的研究提供新的思路和方法。采用网站预测蛋白激酶的“守门员”残基,用载体回补法对其进行突变获得相应的类似物敏感型(analog-sensitive,as)突变体gpmk1-as与pmk1-as,并检测类似物敏感型蛋白激酶的功能及其对ATP类似物抑制剂1-NM-PP1的敏感性。结果显示,Gpmk1与Pmk1的守门员残基分别为Q103和Q104,此位点在多个代表性真菌中均十分保守;类似物敏感型突变体gpmk1-as的菌落生长速度与野生型PH-1一致,均快于Gpmk1敲除突变体,Pmk1-as能够产生与野生型Guy11一样成熟的黑化附着孢,而Pmk1敲除突变体无法产生;在5μmol/L的1-NM-PP1条件下,gpmk1-as的菌落生长速度下降,但PH-1正常生长,在10μmol/L的1-NM-PP条件下,pmk1-as无法形成附着孢,但Guy11可以形成成熟的黑化附着孢。结果表明,Gpmk1和Pmk1的类似物敏感型蛋白激酶均能行使正常的蛋白功能,却对ATP类似物抑制剂1-NM-PP1十分敏感。 展开更多
关键词 植物病原真菌 蛋白激酶 人工改造 化学遗传学技术 类似物敏感型
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Nano-scale Bias-scalable CMOS Analog Computational Circuits Using Margin Propagation
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作者 GU Ming 《机床与液压》 北大核心 2012年第19期1-8,共8页
Approximation techniques are useful for implementing pattern recognizers, communication decoders and sensory processing algorithms where computational precision is not critical to achieve the desired system level perf... Approximation techniques are useful for implementing pattern recognizers, communication decoders and sensory processing algorithms where computational precision is not critical to achieve the desired system level performance. In our previous work, we had proposed margin propagation (MP) as an efficient piece-wise linear (PWL) approximation technique to a log-sum-exp function and had demonstrated its advantages for implementing probabilistic decoders. In this paper, we present a systematic and a generalized approach for synthesizing analog piecewise-linear (PWL) computing circuits using the MP principle. MP circuits use only addition, subtraction and threshold operations and hence can be implemented using universal conservation principles like the Kirchoff's current law. Thus, unlike the conventional translinear CMOS current-mode circuits, the operation of the MP circuits are functionally similar in weak, moderate and strong inversion regimes of the MOS transistor making the design approach bias-scalable. This paper presents measured results from MP circuits prototyped in a 0.5μm standard CMOS process verifying the bias-scalable property. As an example, we apply the synthesis approach towards designing linear classifiers and verify its performance using measured results. 展开更多
关键词 机床行业 液压系统 产品介绍 创新
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含类虚拟同步发电机和柔性负荷的直流微电网大信号稳定控制方法 被引量:5
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作者 王慧 赵书强 +3 位作者 陈旭博 孟建辉 田艳军 高本锋 《电工技术学报》 北大核心 2025年第3期705-716,共12页
直流微电网稳态工作点切换、负荷变化较大时经常会出现暂态失稳现象,属于比较典型的“大信号失稳”工况,传统基于小信号的解决方法难以应对。为此,该文提出一种考虑类虚拟同步发电机(AVSG)控制参数和柔性负荷灵活调节的稳定控制方法。... 直流微电网稳态工作点切换、负荷变化较大时经常会出现暂态失稳现象,属于比较典型的“大信号失稳”工况,传统基于小信号的解决方法难以应对。为此,该文提出一种考虑类虚拟同步发电机(AVSG)控制参数和柔性负荷灵活调节的稳定控制方法。首先建立直流微电网的Takagi-Sugeno(TS)模糊模型。然后,借助线性矩阵不等式(LMI)工具构建Lyapunov函数以估计目标稳态点的吸引域。若目标稳态点的最大估计吸引域(LEDA)包含初始稳态点,则系统是渐近稳定的;否则存在失稳的风险。此时,利用灵活可调的虚拟阻尼、虚拟惯量和柔性负荷等资源,让目标稳态点的LEDA直接或者间接包含初始稳态点,从而消除振荡失稳的风险。研究结果表明:基于吸引域理论改进虚拟阻尼和虚拟惯量等控制参数以及工作点运行轨迹,是一种实用且有效保障系统稳定运行的方法。最后,通过硬件在环仿真(HIL)进行了验证。 展开更多
关键词 直流微电网 大信号稳定 吸引域估计 类虚拟同步发电机 柔性负荷
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波形的产生、分解与合成实验——模拟电子技术“口袋实验板”开发与应用 被引量:1
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作者 曾宪阳 杨红莉 +2 位作者 黄家才 张国玉 褚南峰 《实验室研究与探索》 北大核心 2025年第2期5-9,共5页
针对学生在“模拟电子技术”课程中兴趣不高和学习效果不佳的问题,设计了一款便携式口袋实验板,旨在提升学生的学习动力。该实验板具备开展多项与波形相关实验的功能,尤其侧重于波形产生、分解与合成等关键实验。首先,利用方波发生器产... 针对学生在“模拟电子技术”课程中兴趣不高和学习效果不佳的问题,设计了一款便携式口袋实验板,旨在提升学生的学习动力。该实验板具备开展多项与波形相关实验的功能,尤其侧重于波形产生、分解与合成等关键实验。首先,利用方波发生器产生方波信号,并通过带通滤波器提取基波、3次谐波、5次谐波以及7次谐波信号,完成波形的分解实验。然后通过移相器调节各信号相位,并通过加法器将这些信号叠加合成,最终还原为方波信号,完成波形的合成实验。该实验不仅可验证傅里叶级数理论,还可激发学生对“模拟电子技术”和“信号与系统”等课程的兴趣。此外,该口袋实验板有效解决了设备资源短缺问题,增强了学生学习的自主性和灵活性。 展开更多
关键词 波形的分解 波形的合成 口袋实验室 模拟电子技术
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高速电动机控制系统反馈信号调理电路实验方案设计 被引量:2
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作者 王飞飞 陈炫萧 金浩 《实验室研究与探索》 北大核心 2025年第2期127-132,共6页
为了解决高速磁浮电动机高精度反馈控制问题,设计了一套高速电动机控制系统信号调理电路实验方案,包含电路设计、频域理论计算、仿真验证与实验验证。通过二阶滤波环节的参数匹配,实现调理电路的频域指标设计,确保调理电路能够有效过滤... 为了解决高速磁浮电动机高精度反馈控制问题,设计了一套高速电动机控制系统信号调理电路实验方案,包含电路设计、频域理论计算、仿真验证与实验验证。通过二阶滤波环节的参数匹配,实现调理电路的频域指标设计,确保调理电路能够有效过滤噪声并满足频域指标要求;采用Simulink、Multisim仿真平台对所设计的电路进行时域与频域验证,确保其在理论模型下的可靠性和稳定性;基于Altium Designer完成电路原理图与印制电路板设计,确保电路紧凑性与可靠性;利用实验验证所设计电路有效性以及在不同负载和转速下电路对位移和电流信号处理的优异稳定性与灵敏度。通过对电动机磁悬浮轴承位移和电流信号的准确反馈,有效提升系统的响应速度和控制精度,实现高速磁悬浮电动机的高动态控制。 展开更多
关键词 模拟电路课程设计 磁悬浮轴承 信号调理电路 电动机转速测量
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基于广义换热网络的质量交换网络质能比拟及全局优化 被引量:1
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作者 肖媛 陈怡 +1 位作者 刘思琪 崔国民 《化工进展》 北大核心 2025年第1期121-134,共14页
质量交换网络是过程系统高效经济回收污染物或杂质的重要途径,其中组分浓度的小尺度特征对于其求解域和全局优化性能存在一定限制。基于质量传递和能量传递比拟理论,本文假设了单位高度塔板提供有效传质的塔板质量,建立了非连续传质的... 质量交换网络是过程系统高效经济回收污染物或杂质的重要途径,其中组分浓度的小尺度特征对于其求解域和全局优化性能存在一定限制。基于质量传递和能量传递比拟理论,本文假设了单位高度塔板提供有效传质的塔板质量,建立了非连续传质的板式塔和广义换热器的比拟关系;在此基础上,将小尺度质量交换网络比拟为广义换热网络,进而采用节点非结构模型和强制进化随机游走算法对广义换热网络进行全局优化;最后,将优化所得的广义换热网络回归为质量交换网络,使其满足传质可行性约束。算例分析表明,该方法可有效拓展质量交换网络搜索空间,提升流股匹配的多样性和全局优化性能。同时,灵活调整比拟尺度和协调系数能够进一步丰富优化路径,提升最优解的质量,获得了R2S3算例和R2S2算例优于文献最优的结构。 展开更多
关键词 过程系统 质量交换网络 质能比拟 广义换热网络 全局优化 强制进化随机游走算法
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